Exact Mass: 357.0759

Exact Mass Matches: 357.0759

Found 1 metabolites which its exact mass value is equals to given mass value 357.0759, within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error 4.0E-5 dalton.

Ischemin (sodium)

Ischemin (sodium)

C15H16N3NaO4S (357.0759)


Ischemin sodium is a CBP bromodomain inhibitor that inhibits p53 interaction with CBP and transcriptional activity in cells. Ischemin sodium salt inhibits p53-induced p21 activation with an IC50 value of 5 μM. Ischemin sodium salt also prevents apoptosis in ischemic cardiomyocytes. Ischemin sodium salt can be used in the study of cardiovascular diseases (such as myocardial ischemia)[1].