Exact Mass: 357.0759

Exact Mass Matches: 357.0759

Found 1 metabolites which its exact mass value is equals to given mass value 357.0759, within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error 8.0E-6 dalton.

Ischemin (sodium)

Ischemin (sodium)

C15H16N3NaO4S (357.0759)


Ischemin sodium is a CBP bromodomain inhibitor that inhibits p53 interaction with CBP and transcriptional activity in cells. Ischemin sodium salt inhibits p53-induced p21 activation with an IC50 value of 5 μM. Ischemin sodium salt also prevents apoptosis in ischemic cardiomyocytes. Ischemin sodium salt can be used in the study of cardiovascular diseases (such as myocardial ischemia)[1].