Exact Mass: 341.2515

Exact Mass Matches: 341.2515

Found 42 metabolites which its exact mass value is equals to given mass value 341.2515, within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error 0.001 dalton.

trans-2-Dodecenoylcarnitine

(4S)-4-[(2E)-Dodec-2-enoyloxy]-4-(trimethylazaniumyl)butanoic acid

C19H35NO4 (341.2566)


trans-2-Dodecenoylcarnitine is an acylcarnitine. More specifically, it is an trans-2-dodecenoic acid ester of carnitine. Acylcarnitines were first discovered more than 70 year ago (PMID: 13825279). It is believed that there are more than 1000 types of acylcarnitines in the human body. The general role of acylcarnitines is to transport acyl-groups (organic acids and fatty acids) from the cytoplasm into the mitochondria so that they can be broken down to produce energy.  This process is known as beta-oxidation. According to a recent review [Dambrova et al. 2021, Physiological Reviews], acylcarnitines (ACs) can be classified into 9 different categories depending on the type and size of their acyl-group: 1) short-chain ACs; 2) medium-chain ACs; 3) long-chain ACs; 4) very long-chain ACs; 5) hydroxy ACs; 6) branched chain ACs; 7) unsaturated ACs; 8) dicarboxylic ACs and 9) miscellaneous ACs. Short-chain ACs have acyl-groups with two to five carbons (C2-C5), medium-chain ACs have acyl-groups with six to thirteen carbons (C6-C13), long-chain ACs have acyl-groups with fourteen to twenty once carbons (C14-C21) and very long-chain ACs have acyl groups with more than 22 carbons. trans-2-Dodecenoylcarnitine is therefore classified as a medium chain AC. As a medium-chain acylcarnitine trans-2-dodecenoylcarnitine is somewhat less abundant than short-chain acylcarnitines. These are formed either through esterification with L-carnitine or through the peroxisomal metabolism of longer chain acylcarnitines (PMID: 30540494). Many medium-chain acylcarnitines can serve as useful markers for inherited disorders of fatty acid metabolism. In particular trans-2-dodecenoylcarnitine is elevated in the blood or plasma of individuals with mitochondrial dysfunction in diabetes patients (PMID: 28726959) and children obesity (PMID: 23108202). It is also decreased in the blood or plasma of individuals with placental abruption (PMID: 27300725) increase in dodecanoylcarnitine/dodecenoylcarnitine (c12 / c12:1). Carnitine octanoyltransferase (CrOT, EC:2.3.1.137) is responsible for the synthesis of all medium-chain (MCAC, C5-C12) and medium-length branched-chain acylcarnitines in peroxisomes (PMID: 10486279). The study of acylcarnitines is an active area of research and it is likely that many novel acylcarnitines will be discovered in the coming years. It is also likely that many novel roles in health and disease will be uncovered. An excellent review of the current state of knowledge for acylcarnitines is available at [Dambrova et al. 2021, Physiological Reviews].

   

(9E)-Dodecenoylcarnitine

3-(dodec-9-enoyloxy)-4-(trimethylazaniumyl)butanoate

C19H35NO4 (341.2566)


(9E)-Dodecenoylcarnitine is an acylcarnitine. More specifically, it is an (9E)-dodec-9-enoic acid ester of carnitine. Acylcarnitines were first discovered more than 70 year ago (PMID: 13825279). It is believed that there are more than 1000 types of acylcarnitines in the human body. The general role of acylcarnitines is to transport acyl-groups (organic acids and fatty acids) from the cytoplasm into the mitochondria so that they can be broken down to produce energy. This process is known as beta-oxidation. According to a recent review [Dambrova et al. 2021, Physiological Reviews], acylcarnitines (ACs) can be classified into 9 different categories depending on the type and size of their acyl-group: 1) short-chain ACs; 2) medium-chain ACs; 3) long-chain ACs; 4) very long-chain ACs; 5) hydroxy ACs; 6) branched chain ACs; 7) unsaturated ACs; 8) dicarboxylic ACs and 9) miscellaneous ACs. Short-chain ACs have acyl-groups with two to five carbons (C2-C5), medium-chain ACs have acyl-groups with six to thirteen carbons (C6-C13), long-chain ACs have acyl-groups with fourteen to twenty once carbons (C14-C21) and very long-chain ACs have acyl groups with more than 22 carbons. (9E)-Dodecenoylcarnitine is therefore classified as a medium chain AC. As a medium-chain acylcarnitine (9E)-Dodecenoylcarnitine is somewhat less abundant than short-chain acylcarnitines. These are formed either through esterification with L-carnitine or through the peroxisomal metabolism of longer chain acylcarnitines (PMID: 30540494). Many medium-chain acylcarnitines can serve as useful markers for inherited disorders of fatty acid metabolism. In particular (9E)-Dodecenoylcarnitine is elevated in the blood or plasma of individuals with mitochondrial dysfunction in diabetes patients (PMID: 28726959) and children obesity (PMID: 23108202). It is also decreased in the blood or plasma of individuals with placental abruption (PMID: 27300725) increase in dodecanoylcarnitine/dodecenoylcarnitine (c12 / c12:1). Carnitine octanoyltransferase (CrOT, EC:2.3.1.137) is responsible for the synthesis of all medium-chain (MCAC, C5-C12) and medium-length branched-chain acylcarnitines in peroxisomes (PMID: 10486279). The study of acylcarnitines is an active area of research and it is likely that many novel acylcarnitines will be discovered in the coming years. It is also likely that many novel roles in health and disease will be uncovered. An excellent review of the current state of knowledge for acylcarnitines is available at [Dambrova et al. 2021, Physiological Reviews].

   

4-Dodecenoylcarnitine

3-(dodec-4-enoyloxy)-4-(trimethylazaniumyl)butanoate

C19H35NO4 (341.2566)


4-Dodecenoylcarnitine is an acylcarnitine. More specifically, it is an dodec-4-enoic acid ester of carnitine. Acylcarnitines were first discovered more than 70 year ago (PMID: 13825279). It is believed that there are more than 1000 types of acylcarnitines in the human body. The general role of acylcarnitines is to transport acyl-groups (organic acids and fatty acids) from the cytoplasm into the mitochondria so that they can be broken down to produce energy. This process is known as beta-oxidation. According to a recent review [Dambrova et al. 2021, Physiological Reviews], acylcarnitines (ACs) can be classified into 9 different categories depending on the type and size of their acyl-group: 1) short-chain ACs; 2) medium-chain ACs; 3) long-chain ACs; 4) very long-chain ACs; 5) hydroxy ACs; 6) branched chain ACs; 7) unsaturated ACs; 8) dicarboxylic ACs and 9) miscellaneous ACs. Short-chain ACs have acyl-groups with two to five carbons (C2-C5), medium-chain ACs have acyl-groups with six to thirteen carbons (C6-C13), long-chain ACs have acyl-groups with fourteen to twenty once carbons (C14-C21) and very long-chain ACs have acyl groups with more than 22 carbons. 4-Dodecenoylcarnitine is therefore classified as a medium chain AC. As a medium-chain acylcarnitine 4-Dodecenoylcarnitine is somewhat less abundant than short-chain acylcarnitines. These are formed either through esterification with L-carnitine or through the peroxisomal metabolism of longer chain acylcarnitines (PMID: 30540494). Many medium-chain acylcarnitines can serve as useful markers for inherited disorders of fatty acid metabolism. In particular 4-Dodecenoylcarnitine is elevated in the blood or plasma of individuals with mitochondrial dysfunction in diabetes patients (PMID: 28726959) and children obesity (PMID: 23108202). It is also decreased in the blood or plasma of individuals with placental abruption (PMID: 27300725) increase in dodecanoylcarnitine/dodecenoylcarnitine (c12 / c12:1). Carnitine octanoyltransferase (CrOT, EC:2.3.1.137) is responsible for the synthesis of all medium-chain (MCAC, C5-C12) and medium-length branched-chain acylcarnitines in peroxisomes (PMID: 10486279). The study of acylcarnitines is an active area of research and it is likely that many novel acylcarnitines will be discovered in the coming years. It is also likely that many novel roles in health and disease will be uncovered. An excellent review of the current state of knowledge for acylcarnitines is available at [Dambrova et al. 2021, Physiological Reviews].

   

11-Dodecenoylcarnitine

3-(dodec-11-enoyloxy)-4-(trimethylazaniumyl)butanoate

C19H35NO4 (341.2566)


11-Dodecenoylcarnitine is an acylcarnitine. More specifically, it is an Dodecenoylcarnitine ester of carnitine. Acylcarnitines were first discovered more than 70 year ago (PMID: 13825279). It is believed that there are more than 1000 types of acylcarnitines in the human body. The general role of acylcarnitines is to transport acyl-groups (organic acids and fatty acids) from the cytoplasm into the mitochondria so that they can be broken down to produce energy. This process is known as beta-oxidation. According to a recent review [Dambrova et al. 2021, Physiological Reviews], acylcarnitines (ACs) can be classified into 9 different categories depending on the type and size of their acyl-group: 1) short-chain ACs; 2) medium-chain ACs; 3) long-chain ACs; 4) very long-chain ACs; 5) hydroxy ACs; 6) branched chain ACs; 7) unsaturated ACs; 8) dicarboxylic ACs and 9) miscellaneous ACs. Short-chain ACs have acyl-groups with two to five carbons (C2-C5), medium-chain ACs have acyl-groups with six to thirteen carbons (C6-C13), long-chain ACs have acyl-groups with fourteen to twenty once carbons (C14-C21) and very long-chain ACs have acyl groups with more than 22 carbons. 11-Dodecenoylcarnitine is therefore classified as a medium chain AC. As a medium-chain acylcarnitine 11-Dodecenoylcarnitine is somewhat less abundant than short-chain acylcarnitines. These are formed either through esterification with L-carnitine or through the peroxisomal metabolism of longer chain acylcarnitines (PMID: 30540494). Many medium-chain acylcarnitines can serve as useful markers for inherited disorders of fatty acid metabolism. In particular 11-Dodecenoylcarnitine is elevated in the blood or plasma of individuals with mitochondrial dysfunction in diabetes patients (PMID: 28726959) and children obesity (PMID: 23108202). It is also decreased in the blood or plasma of individuals with placental abruption (PMID: 27300725) increase in dodecanoylcarnitine/dodecenoylcarnitine (c12 / c12:1). Carnitine octanoyltransferase (CrOT, EC:2.3.1.137) is responsible for the synthesis of all medium-chain (MCAC, C5-C12) and medium-length branched-chain acylcarnitines in peroxisomes (PMID: 10486279). The study of acylcarnitines is an active area of research and it is likely that many novel acylcarnitines will be discovered in the coming years. It is also likely that many novel roles in health and disease will be uncovered. An excellent review of the current state of knowledge for acylcarnitines is available at [Dambrova et al. 2021, Physiological Reviews].

   

5-Dodecenoylcarnitine

3-(dodec-5-enoyloxy)-4-(trimethylazaniumyl)butanoate

C19H35NO4 (341.2566)


5-Dodecenoylcarnitine is an acylcarnitine. More specifically, it is an dodec-5-enoic acid ester of carnitine. Acylcarnitines were first discovered more than 70 year ago (PMID: 13825279). It is believed that there are more than 1000 types of acylcarnitines in the human body. The general role of acylcarnitines is to transport acyl-groups (organic acids and fatty acids) from the cytoplasm into the mitochondria so that they can be broken down to produce energy. This process is known as beta-oxidation. According to a recent review [Dambrova et al. 2021, Physiological Reviews], acylcarnitines (ACs) can be classified into 9 different categories depending on the type and size of their acyl-group: 1) short-chain ACs; 2) medium-chain ACs; 3) long-chain ACs; 4) very long-chain ACs; 5) hydroxy ACs; 6) branched chain ACs; 7) unsaturated ACs; 8) dicarboxylic ACs and 9) miscellaneous ACs. Short-chain ACs have acyl-groups with two to five carbons (C2-C5), medium-chain ACs have acyl-groups with six to thirteen carbons (C6-C13), long-chain ACs have acyl-groups with fourteen to twenty once carbons (C14-C21) and very long-chain ACs have acyl groups with more than 22 carbons. 5-Dodecenoylcarnitine is therefore classified as a medium chain AC. As a medium-chain acylcarnitine 5-Dodecenoylcarnitine is somewhat less abundant than short-chain acylcarnitines. These are formed either through esterification with L-carnitine or through the peroxisomal metabolism of longer chain acylcarnitines (PMID: 30540494). Many medium-chain acylcarnitines can serve as useful markers for inherited disorders of fatty acid metabolism. In particular 5-Dodecenoylcarnitine is elevated in the blood or plasma of individuals with mitochondrial dysfunction in diabetes patients (PMID: 28726959) and children obesity (PMID: 23108202). It is also decreased in the blood or plasma of individuals with placental abruption (PMID: 27300725) increase in dodecanoylcarnitine/dodecenoylcarnitine (c12 / c12:1). Carnitine octanoyltransferase (CrOT, EC:2.3.1.137) is responsible for the synthesis of all medium-chain (MCAC, C5-C12) and medium-length branched-chain acylcarnitines in peroxisomes (PMID: 10486279). The study of acylcarnitines is an active area of research and it is likely that many novel acylcarnitines will be discovered in the coming years. It is also likely that many novel roles in health and disease will be uncovered. An excellent review of the current state of knowledge for acylcarnitines is available at [Dambrova et al. 2021, Physiological Reviews].

   

7-Dodecenoylcarnitine

3-(dodec-7-enoyloxy)-4-(trimethylazaniumyl)butanoate

C19H35NO4 (341.2566)


7-Dodecenoylcarnitine is an acylcarnitine. More specifically, it is an dodec-7-enoic acid ester of carnitine. Acylcarnitines were first discovered more than 70 year ago (PMID: 13825279). It is believed that there are more than 1000 types of acylcarnitines in the human body. The general role of acylcarnitines is to transport acyl-groups (organic acids and fatty acids) from the cytoplasm into the mitochondria so that they can be broken down to produce energy. This process is known as beta-oxidation. According to a recent review [Dambrova et al. 2021, Physiological Reviews], acylcarnitines (ACs) can be classified into 9 different categories depending on the type and size of their acyl-group: 1) short-chain ACs; 2) medium-chain ACs; 3) long-chain ACs; 4) very long-chain ACs; 5) hydroxy ACs; 6) branched chain ACs; 7) unsaturated ACs; 8) dicarboxylic ACs and 9) miscellaneous ACs. Short-chain ACs have acyl-groups with two to five carbons (C2-C5), medium-chain ACs have acyl-groups with six to thirteen carbons (C6-C13), long-chain ACs have acyl-groups with fourteen to twenty once carbons (C14-C21) and very long-chain ACs have acyl groups with more than 22 carbons. 7-Dodecenoylcarnitine is therefore classified as a medium chain AC. As a medium-chain acylcarnitine 7-Dodecenoylcarnitine is somewhat less abundant than short-chain acylcarnitines. These are formed either through esterification with L-carnitine or through the peroxisomal metabolism of longer chain acylcarnitines (PMID: 30540494). Many medium-chain acylcarnitines can serve as useful markers for inherited disorders of fatty acid metabolism. In particular 7-Dodecenoylcarnitine is elevated in the blood or plasma of individuals with mitochondrial dysfunction in diabetes patients (PMID: 28726959) and children obesity (PMID: 23108202). It is also decreased in the blood or plasma of individuals with placental abruption (PMID: 27300725) increase in dodecanoylcarnitine/dodecenoylcarnitine (c12 / c12:1). Carnitine octanoyltransferase (CrOT, EC:2.3.1.137) is responsible for the synthesis of all medium-chain (MCAC, C5-C12) and medium-length branched-chain acylcarnitines in peroxisomes (PMID: 10486279). The study of acylcarnitines is an active area of research and it is likely that many novel acylcarnitines will be discovered in the coming years. It is also likely that many novel roles in health and disease will be uncovered. An excellent review of the current state of knowledge for acylcarnitines is available at [Dambrova et al. 2021, Physiological Reviews].

   

8-Dodecenoylcarnitine

3-(dodec-8-enoyloxy)-4-(trimethylazaniumyl)butanoate

C19H35NO4 (341.2566)


8-Dodecenoylcarnitine is an acylcarnitine. More specifically, it is an dodec-8-enoic acid ester of carnitine. Acylcarnitines were first discovered more than 70 year ago (PMID: 13825279). It is believed that there are more than 1000 types of acylcarnitines in the human body. The general role of acylcarnitines is to transport acyl-groups (organic acids and fatty acids) from the cytoplasm into the mitochondria so that they can be broken down to produce energy. This process is known as beta-oxidation. According to a recent review [Dambrova et al. 2021, Physiological Reviews], acylcarnitines (ACs) can be classified into 9 different categories depending on the type and size of their acyl-group: 1) short-chain ACs; 2) medium-chain ACs; 3) long-chain ACs; 4) very long-chain ACs; 5) hydroxy ACs; 6) branched chain ACs; 7) unsaturated ACs; 8) dicarboxylic ACs and 9) miscellaneous ACs. Short-chain ACs have acyl-groups with two to five carbons (C2-C5), medium-chain ACs have acyl-groups with six to thirteen carbons (C6-C13), long-chain ACs have acyl-groups with fourteen to twenty once carbons (C14-C21) and very long-chain ACs have acyl groups with more than 22 carbons. 8-Dodecenoylcarnitine is therefore classified as a medium chain AC. As a medium-chain acylcarnitine 8-Dodecenoylcarnitine is somewhat less abundant than short-chain acylcarnitines. These are formed either through esterification with L-carnitine or through the peroxisomal metabolism of longer chain acylcarnitines (PMID: 30540494). Many medium-chain acylcarnitines can serve as useful markers for inherited disorders of fatty acid metabolism. In particular 8-Dodecenoylcarnitine is elevated in the blood or plasma of individuals with mitochondrial dysfunction in diabetes patients (PMID: 28726959) and children obesity (PMID: 23108202). It is also decreased in the blood or plasma of individuals with placental abruption (PMID: 27300725) increase in dodecanoylcarnitine/dodecenoylcarnitine (c12 / c12:1). Carnitine octanoyltransferase (CrOT, EC:2.3.1.137) is responsible for the synthesis of all medium-chain (MCAC, C5-C12) and medium-length branched-chain acylcarnitines in peroxisomes (PMID: 10486279). The study of acylcarnitines is an active area of research and it is likely that many novel acylcarnitines will be discovered in the coming years. It is also likely that many novel roles in health and disease will be uncovered. An excellent review of the current state of knowledge for acylcarnitines is available at [Dambrova et al. 2021, Physiological Reviews].

   

2-Dodecenoylcarnitine

3-(dodec-2-enoyloxy)-4-(trimethylazaniumyl)butanoate

C19H35NO4 (341.2566)


2-Dodecenoylcarnitine is an acylcarnitine. More specifically, it is an dodec-2-enoic acid ester of carnitine. Acylcarnitines were first discovered more than 70 year ago (PMID: 13825279). It is believed that there are more than 1000 types of acylcarnitines in the human body. The general role of acylcarnitines is to transport acyl-groups (organic acids and fatty acids) from the cytoplasm into the mitochondria so that they can be broken down to produce energy. This process is known as beta-oxidation. According to a recent review [Dambrova et al. 2021, Physiological Reviews], acylcarnitines (ACs) can be classified into 9 different categories depending on the type and size of their acyl-group: 1) short-chain ACs; 2) medium-chain ACs; 3) long-chain ACs; 4) very long-chain ACs; 5) hydroxy ACs; 6) branched chain ACs; 7) unsaturated ACs; 8) dicarboxylic ACs and 9) miscellaneous ACs. Short-chain ACs have acyl-groups with two to five carbons (C2-C5), medium-chain ACs have acyl-groups with six to thirteen carbons (C6-C13), long-chain ACs have acyl-groups with fourteen to twenty once carbons (C14-C21) and very long-chain ACs have acyl groups with more than 22 carbons. 2-Dodecenoylcarnitine is therefore classified as a medium chain AC. As a medium-chain acylcarnitine 2-Dodecenoylcarnitine is somewhat less abundant than short-chain acylcarnitines. These are formed either through esterification with L-carnitine or through the peroxisomal metabolism of longer chain acylcarnitines (PMID: 30540494). Many medium-chain acylcarnitines can serve as useful markers for inherited disorders of fatty acid metabolism. In particular 2-Dodecenoylcarnitine is elevated in the blood or plasma of individuals with mitochondrial dysfunction in diabetes patients (PMID: 28726959) and children obesity (PMID: 23108202). It is also decreased in the blood or plasma of individuals with placental abruption (PMID: 27300725) increase in dodecanoylcarnitine/dodecenoylcarnitine (c12 / c12:1). Carnitine octanoyltransferase (CrOT, EC:2.3.1.137) is responsible for the synthesis of all medium-chain (MCAC, C5-C12) and medium-length branched-chain acylcarnitines in peroxisomes (PMID: 10486279). The study of acylcarnitines is an active area of research and it is likely that many novel acylcarnitines will be discovered in the coming years. It is also likely that many novel roles in health and disease will be uncovered. An excellent review of the current state of knowledge for acylcarnitines is available at [Dambrova et al. 2021, Physiological Reviews].

   

3-Dodecenoylcarnitine

3-(dodec-3-enoyloxy)-4-(trimethylazaniumyl)butanoate

C19H35NO4 (341.2566)


3-Dodecenoylcarnitine is an acylcarnitine. More specifically, it is an dodec-3-enoic acid ester of carnitine. Acylcarnitines were first discovered more than 70 year ago (PMID: 13825279). It is believed that there are more than 1000 types of acylcarnitines in the human body. The general role of acylcarnitines is to transport acyl-groups (organic acids and fatty acids) from the cytoplasm into the mitochondria so that they can be broken down to produce energy. This process is known as beta-oxidation. According to a recent review [Dambrova et al. 2021, Physiological Reviews], acylcarnitines (ACs) can be classified into 9 different categories depending on the type and size of their acyl-group: 1) short-chain ACs; 2) medium-chain ACs; 3) long-chain ACs; 4) very long-chain ACs; 5) hydroxy ACs; 6) branched chain ACs; 7) unsaturated ACs; 8) dicarboxylic ACs and 9) miscellaneous ACs. Short-chain ACs have acyl-groups with two to five carbons (C2-C5), medium-chain ACs have acyl-groups with six to thirteen carbons (C6-C13), long-chain ACs have acyl-groups with fourteen to twenty once carbons (C14-C21) and very long-chain ACs have acyl groups with more than 22 carbons. 3-Dodecenoylcarnitine is therefore classified as a medium chain AC. As a medium-chain acylcarnitine 3-Dodecenoylcarnitine is somewhat less abundant than short-chain acylcarnitines. These are formed either through esterification with L-carnitine or through the peroxisomal metabolism of longer chain acylcarnitines (PMID: 30540494). Many medium-chain acylcarnitines can serve as useful markers for inherited disorders of fatty acid metabolism. In particular 3-Dodecenoylcarnitine is elevated in the blood or plasma of individuals with mitochondrial dysfunction in diabetes patients (PMID: 28726959) and children obesity (PMID: 23108202). It is also decreased in the blood or plasma of individuals with placental abruption (PMID: 27300725) increase in dodecanoylcarnitine/dodecenoylcarnitine (c12 / c12:1). Carnitine octanoyltransferase (CrOT, EC:2.3.1.137) is responsible for the synthesis of all medium-chain (MCAC, C5-C12) and medium-length branched-chain acylcarnitines in peroxisomes (PMID: 10486279). The study of acylcarnitines is an active area of research and it is likely that many novel acylcarnitines will be discovered in the coming years. It is also likely that many novel roles in health and disease will be uncovered. An excellent review of the current state of knowledge for acylcarnitines is available at [Dambrova et al. 2021, Physiological Reviews].

   

6-Dodecenoylcarnitine

3-(dodec-6-enoyloxy)-4-(trimethylazaniumyl)butanoate

C19H35NO4 (341.2566)


6-Dodecenoylcarnitine is an acylcarnitine. More specifically, it is an dodec-6-enoic acid ester of carnitine. Acylcarnitines were first discovered more than 70 year ago (PMID: 13825279). It is believed that there are more than 1000 types of acylcarnitines in the human body. The general role of acylcarnitines is to transport acyl-groups (organic acids and fatty acids) from the cytoplasm into the mitochondria so that they can be broken down to produce energy. This process is known as beta-oxidation. According to a recent review [Dambrova et al. 2021, Physiological Reviews], acylcarnitines (ACs) can be classified into 9 different categories depending on the type and size of their acyl-group: 1) short-chain ACs; 2) medium-chain ACs; 3) long-chain ACs; 4) very long-chain ACs; 5) hydroxy ACs; 6) branched chain ACs; 7) unsaturated ACs; 8) dicarboxylic ACs and 9) miscellaneous ACs. Short-chain ACs have acyl-groups with two to five carbons (C2-C5), medium-chain ACs have acyl-groups with six to thirteen carbons (C6-C13), long-chain ACs have acyl-groups with fourteen to twenty once carbons (C14-C21) and very long-chain ACs have acyl groups with more than 22 carbons. 6-Dodecenoylcarnitine is therefore classified as a medium chain AC. As a medium-chain acylcarnitine 6-Dodecenoylcarnitine is somewhat less abundant than short-chain acylcarnitines. These are formed either through esterification with L-carnitine or through the peroxisomal metabolism of longer chain acylcarnitines (PMID: 30540494). Many medium-chain acylcarnitines can serve as useful markers for inherited disorders of fatty acid metabolism. In particular 6-Dodecenoylcarnitine is elevated in the blood or plasma of individuals with mitochondrial dysfunction in diabetes patients (PMID: 28726959) and children obesity (PMID: 23108202). It is also decreased in the blood or plasma of individuals with placental abruption (PMID: 27300725) increase in dodecanoylcarnitine/dodecenoylcarnitine (c12 / c12:1). Carnitine octanoyltransferase (CrOT, EC:2.3.1.137) is responsible for the synthesis of all medium-chain (MCAC, C5-C12) and medium-length branched-chain acylcarnitines in peroxisomes (PMID: 10486279). The study of acylcarnitines is an active area of research and it is likely that many novel acylcarnitines will be discovered in the coming years. It is also likely that many novel roles in health and disease will be uncovered. An excellent review of the current state of knowledge for acylcarnitines is available at [Dambrova et al. 2021, Physiological Reviews].

   

Dodecenoylcarnitine

3-Hydroxy-4-oxo-3-[(trimethylazaniumyl)methyl]pentadec-5-enoic acid

C19H35NO4 (341.2566)


   

(+)-Panacosmine

(+)-Panacosmine

C21H31N3O (341.2467)


   

341A Allopumiliotoxin

341A Allopumiliotoxin

C19H35NO4 (341.2566)


   

CAY10580

2-(3-hydroxyoctyl)-5-oxo-1-pyrrolidineheptanoic acid

C19H35NO4 (341.2566)


   

(4R,6R,6S,7S,8R)-6-(2-hydroxypentan-2-yl)-4,8-dimethyldecahydro-5H-spiro[indolizine-6,2-pyran]-7,8-diol

(4R,6R,6S,7S,8R)-6-(2-hydroxypentan-2-yl)-4,8-dimethyldecahydro-5H-spiro[indolizine-6,2-pyran]-7,8-diol

C19H35NO4 (341.2566)


   

CAR 12:1

3-[(5Z)-dodecenoyloxy]-4-(trimethylazaniumyl)butanoate

C19H35NO4 (341.2566)


   
   

Fentanyl-d5 bromide

Fentanyl-d5 bromide

C22H23D5N2O (341.2515)


   

7-[2-(3-Hydroxyoctyl)-5-oxopyrrolidin-1-YL]heptanoic acid

7-[2-(3-Hydroxyoctyl)-5-oxopyrrolidin-1-YL]heptanoic acid

C19H35NO4 (341.2566)


   

3-Carbamoyl-2-tetradecanamidopropanoate

3-Carbamoyl-2-tetradecanamidopropanoate

C18H33N2O4- (341.244)


   

(E)-3-hydroxy-4-oxo-3-[(trimethylazaniumyl)methyl]pentadec-5-enoate

(E)-3-hydroxy-4-oxo-3-[(trimethylazaniumyl)methyl]pentadec-5-enoate

C19H35NO4 (341.2566)


   

2-Dodecenoylcarnitine

2-Dodecenoylcarnitine

C19H35NO4 (341.2566)


   

4-Dodecenoylcarnitine

4-Dodecenoylcarnitine

C19H35NO4 (341.2566)


   

5-Dodecenoylcarnitine

5-Dodecenoylcarnitine

C19H35NO4 (341.2566)


   

7-Dodecenoylcarnitine

7-Dodecenoylcarnitine

C19H35NO4 (341.2566)


   

8-Dodecenoylcarnitine

8-Dodecenoylcarnitine

C19H35NO4 (341.2566)


   

3-Dodecenoylcarnitine

3-Dodecenoylcarnitine

C19H35NO4 (341.2566)


   

6-Dodecenoylcarnitine

6-Dodecenoylcarnitine

C19H35NO4 (341.2566)


   

(9E)-Dodecenoylcarnitine

(9E)-Dodecenoylcarnitine

C19H35NO4 (341.2566)


   

O-[(5Z)-dodecenoyl]carnitine

O-[(5Z)-dodecenoyl]carnitine

C19H35NO4 (341.2566)


An O-dodecenoylcarnitine having (5Z)-dodecenoyl as the acyl substituent.

   

trans-2-Dodecenoylcarnitine

trans-2-Dodecenoylcarnitine

C19H35NO4 (341.2566)


   

O-dodecenoylcarnitine

O-dodecenoylcarnitine

C19H35NO4 (341.2566)


An O-acylcarnitine in which the acyl group specified is dodecenoyl.

   

O-dodecenoyl-L-carnitine

O-dodecenoyl-L-carnitine

C19H35NO4 (341.2566)


An O-acyl-L-carnitine that is L-carnitine having dodecenoyl group as the acyl substituent in which the position of the double bond is unspecified.

   

NA-Ser 16:1(9Z)

NA-Ser 16:1(9Z)

C19H35NO4 (341.2566)


   

NA-Thr 15:1(9Z)

NA-Thr 15:1(9Z)

C19H35NO4 (341.2566)


   
   
   

(4'r,6r,6's,7s,8r,8as)-6'-[(2r)-2-hydroxypentan-2-yl]-4',8-dimethyl-hexahydrospiro[indolizine-6,2'-oxane]-7,8-diol

(4'r,6r,6's,7s,8r,8as)-6'-[(2r)-2-hydroxypentan-2-yl]-4',8-dimethyl-hexahydrospiro[indolizine-6,2'-oxane]-7,8-diol

C19H35NO4 (341.2566)


   

1-{3-[(2s,6r,8r,9r,11s,13s)-13-(prop-2-en-1-yl)-1,7-diazatetracyclo[7.3.1.0²,⁷.0⁶,¹¹]tridecan-8-yl]-5,6-dihydro-4h-pyridin-1-yl}ethanone

1-{3-[(2s,6r,8r,9r,11s,13s)-13-(prop-2-en-1-yl)-1,7-diazatetracyclo[7.3.1.0²,⁷.0⁶,¹¹]tridecan-8-yl]-5,6-dihydro-4h-pyridin-1-yl}ethanone

C21H31N3O (341.2467)


   

1-{3-[(2s,8r,9r,11s,13s)-13-(prop-2-en-1-yl)-1,7-diazatetracyclo[7.3.1.0²,⁷.0⁶,¹¹]tridecan-8-yl]-5,6-dihydro-4h-pyridin-1-yl}ethanone

1-{3-[(2s,8r,9r,11s,13s)-13-(prop-2-en-1-yl)-1,7-diazatetracyclo[7.3.1.0²,⁷.0⁶,¹¹]tridecan-8-yl]-5,6-dihydro-4h-pyridin-1-yl}ethanone

C21H31N3O (341.2467)


   

6'-(2-hydroxypentan-2-yl)-4',8-dimethyl-hexahydrospiro[indolizine-6,2'-oxane]-7,8-diol

6'-(2-hydroxypentan-2-yl)-4',8-dimethyl-hexahydrospiro[indolizine-6,2'-oxane]-7,8-diol

C19H35NO4 (341.2566)


   

1-{3-[13-(prop-2-en-1-yl)-1,7-diazatetracyclo[7.3.1.0²,⁷.0⁶,¹¹]tridecan-8-yl]-5,6-dihydro-4h-pyridin-1-yl}ethanone

1-{3-[13-(prop-2-en-1-yl)-1,7-diazatetracyclo[7.3.1.0²,⁷.0⁶,¹¹]tridecan-8-yl]-5,6-dihydro-4h-pyridin-1-yl}ethanone

C21H31N3O (341.2467)