Exact Mass: 330.9926024

Exact Mass Matches: 330.9926024

Found 15 metabolites which its exact mass value is equals to given mass value 330.9926024, within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error 0.001 dalton.

Hydroflumethiazide

1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1λ⁶,2,4-benzothiadiazine-7-sulfonamide

C8H8F3N3O4S2 (330.9908324)


Hydroflumethiazide is only found in individuals that have used or taken this drug. It is a thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p822)Hydroflumethiazide is a thiazide diuretic that inhibits water reabsorption in the nephron by inhibiting the sodium-chloride symporter (SLC12A3) in the distal convoluted tubule, which is responsible for 5\\% of total sodium reabsorption. Normally, the sodium-chloride symporter transports sodium and chloride from the lumen into the epithelial cell lining the distal convoluted tubule. The energy for this is provided by a sodium gradient established by sodium-potassium ATPases on the basolateral membrane. Once sodium has entered the cell, it is transported out into the basolateral interstitium via the sodium-potassium ATPase, causing an increase in the osmolarity of the interstitium, thereby establishing an osmotic gradient for water reabsorption. By blocking the sodium-chloride symporter, Hydroflumethiazide effectively reduces the osmotic gradient and water reabsorption throughout the nephron. C - Cardiovascular system > C03 - Diuretics > C03A - Low-ceiling diuretics, thiazides > C03AA - Thiazides, plain D045283 - Natriuretic Agents > D004232 - Diuretics > D049993 - Sodium Chloride Symporter Inhibitors C78275 - Agent Affecting Blood or Body Fluid > C448 - Diuretic > C49185 - Thiazide Diuretic D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D045283 - Natriuretic Agents D049990 - Membrane Transport Modulators

   

Chlozolinate

Ethyl 3-(3,5-dichlorophenyl)-5-methyl-2,4-dioxo-1,3-oxazolidine-5-carboxylic acid

C13H11Cl2NO5 (331.0014256)


   
   

2-CHLORO-N-{4-[(1,3-THIAZOL-2-YLAMINO)SULFONYL]PHENYL}ACETAMIDE

2-CHLORO-N-{4-[(1,3-THIAZOL-2-YLAMINO)SULFONYL]PHENYL}ACETAMIDE

C11H10ClN3O3S2 (330.98521)


   

6-BROMO-2-(5-METHYL-FURAN-2-YL)QUINOLINE-4-CARBOXYLICACID

6-BROMO-2-(5-METHYL-FURAN-2-YL)QUINOLINE-4-CARBOXYLICACID

C15H10BrNO3 (330.98440100000005)


   

4-((3-BROMOPHENYL)AMINO)QUINAZOLINE-6,7-DIOL

4-((3-BROMOPHENYL)AMINO)QUINAZOLINE-6,7-DIOL

C14H10BrN3O2 (330.995634)


   
   

2-[[(4-CHLOROPHENYL)SULFONYL]METHYL]-1,3-THIAZOLE-4-CARBOHYDRAZIDE

2-[[(4-CHLOROPHENYL)SULFONYL]METHYL]-1,3-THIAZOLE-4-CARBOHYDRAZIDE

C11H10ClN3O3S2 (330.98521)


   
   

4-Thiomorpholinecarbodithioic acid [2-(4-chlorophenyl)-2-oxoethyl] ester

4-Thiomorpholinecarbodithioic acid [2-(4-chlorophenyl)-2-oxoethyl] ester

C13H14ClNOS3 (330.9926024)


   
   

5-bromo-2-spiro[1,2-dihydro-4,1,2-benzoxadiazine-3,3-1H-indole]one

5-bromo-2-spiro[1,2-dihydro-4,1,2-benzoxadiazine-3,3-1H-indole]one

C14H10BrN3O2 (330.995634)


   
   

hydroflumethiazide

hydroflumethiazide

C8H8F3N3O4S2 (330.9908324)


C - Cardiovascular system > C03 - Diuretics > C03A - Low-ceiling diuretics, thiazides > C03AA - Thiazides, plain D045283 - Natriuretic Agents > D004232 - Diuretics > D049993 - Sodium Chloride Symporter Inhibitors C78275 - Agent Affecting Blood or Body Fluid > C448 - Diuretic > C49185 - Thiazide Diuretic D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D045283 - Natriuretic Agents D049990 - Membrane Transport Modulators