Exact Mass: 292.168788

Exact Mass Matches: 292.168788

Found 4 metabolites which its exact mass value is equals to given mass value 292.168788, within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error 0.0002 dalton.

Lerisetron

1-benzyl-2-(piperazin-1-yl)-1H-1,3-benzodiazole

C18H20N4 (292.168788)


C78272 - Agent Affecting Nervous System > C66885 - Serotonin Antagonist > C94726 - 5-HT3 Receptor Antagonist C78272 - Agent Affecting Nervous System > C267 - Antiemetic Agent Lerisetron is a potent 5-HT3 antagonists and possess high-affinity binding for the 5-HT3 receptors with pKi value of 9.2. Lerisetron has a potent ability to inhibit the 5-HT-evoked reflex bradycardia in urethane-anesthetized rats[1].

   

6-Ethyl-5-methyl-3-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-2-py razinecarbonitrile

6-Ethyl-5-methyl-3-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-2-py razinecarbonitrile

C18H20N4 (292.168788)


   

N-(3-phenyl-2-propen-1-ylidene)-4-(2-pyridinyl)-1-piperazinamine

N-(3-phenyl-2-propen-1-ylidene)-4-(2-pyridinyl)-1-piperazinamine

C18H20N4 (292.168788)


   

Deschloroclozapine

Deschloroclozapine

C18H20N4 (292.168788)


Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist. Deschloroclozapine binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively. [11C]-Deschloroclozapine is developed as a promising PET tracer for DREADD imaging[1][2][3].