Exact Mass: 291.13179560000003

Exact Mass Matches: 291.13179560000003

Found 147 metabolites which its exact mass value is equals to given mass value 291.13179560000003, within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error 0.001 dalton.

Naproanilide

naproanilide (JMAF only)

C19H17NO2 (291.1259222)

S-(2-Methylbutanoyl)-dihydrolipoamide

[Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase]

C13H25NO2S2 (291.13266300000004)

S-(2-Methylbutanoyl)-dihydrolipoamide-E is an intermediate in isoleucine degradation. S-(2-Methylbutanoyl)-dihydrolipoamide is normally conjugated to a lysine residue of the methylpropanoyltransferase enzyme (E stands for enzyme). The structure shown here is the free form. Specifically S-(2-Methylbutanoyl)-dihydrolipoamide-E is the 2-methylbutanoyl thioester of the reduced lipoyllysine residue in dihydrolipoyllysine-residue (2-methylpropanoyl)transferase. [HMDB] S-(2-Methylbutanoyl)-dihydrolipoamide-E is an intermediate in isoleucine degradation. S-(2-Methylbutanoyl)-dihydrolipoamide is normally conjugated to a lysine residue of the methylpropanoyltransferase enzyme (E stands for enzyme). The structure shown here is the free form. Specifically S-(2-Methylbutanoyl)-dihydrolipoamide-E is the 2-methylbutanoyl thioester of the reduced lipoyllysine residue in dihydrolipoyllysine-residue (2-methylpropanoyl)transferase.

S-(3-Methylbutanoyl)-dihydrolipoamide-E

[Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase]

C13H25NO2S2 (291.13266300000004)

S-(3-Methylbutanoyl)-dihydrolipoamide-E is an intermediate in valine, leucine and isoleucine degradation(KEGG ID C15975 ). It is the second to last step in the synthesis of branched chain fatty acid and is converted from 3-methyl-hydroxybutyl-ThPP via the enzyme 2-oxoisovalerate dehydrogenase [EC:1.2.4.4]. It is then converted to 3-methylbutanoyl-CoA via the enzyme dihydrolipoyllysine-residue (2-methylpropanoyl)transferase[EC:2.3.1.168]. [HMDB] S-(3-Methylbutanoyl)-dihydrolipoamide-E is an intermediate in valine, leucine and isoleucine degradation(KEGG ID C15975 ). It is the second to last step in the synthesis of branched chain fatty acid and is converted from 3-methyl-hydroxybutyl-ThPP via the enzyme 2-oxoisovalerate dehydrogenase [EC:1.2.4.4]. It is then converted to 3-methylbutanoyl-CoA via the enzyme dihydrolipoyllysine-residue (2-methylpropanoyl)transferase[EC:2.3.1.168].

Benzhydramine HCl

Diphenhydramine Hydrochloride

C17H21NO.HCl (291.13898320000004)

D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D000777 - Anesthetics D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents C78272 - Agent Affecting Nervous System > C267 - Antiemetic Agent D005765 - Gastrointestinal Agents > D000932 - Antiemetics D018926 - Anti-Allergic Agents Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB)[1][2].

Seryltryptophan

(2S)-2-{[(2S)-2-amino-1,3-dihydroxypropylidene]amino}-3-(1H-indol-3-yl)propanoate

C14H17N3O4 (291.1219002)

Seryltryptophan is a dipeptide composed of serine and tryptophan. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis.

Tryptophyl-Serine

2-{[2-amino-1-hydroxy-3-(1H-indol-3-yl)propylidene]amino}-3-hydroxypropanoate

C14H17N3O4 (291.1219002)

Tryptophyl-Serine is a dipeptide composed of tryptophan and serine. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis. This dipeptide has not yet been identified in human tissues or biofluids and so it is classified as an Expected metabolite.

2-hydroxy-3-methylbutanedioylcarnitine

3-[(3-carboxy-2-hydroxy-3-methylpropanoyl)oxy]-4-(trimethylazaniumyl)butanoate

C12H21NO7 (291.13179560000003)

2-hydroxy-3-methylbutanedioylcarnitine is an acylcarnitine. More specifically, it is an 2-hydroxy-3-methylbutanedioic acid ester of carnitine. Acylcarnitines were first discovered more than 70 year ago (PMID: 13825279). It is believed that there are more than 1000 types of acylcarnitines in the human body. The general role of acylcarnitines is to transport acyl-groups (organic acids and fatty acids) from the cytoplasm into the mitochondria so that they can be broken down to produce energy. This process is known as beta-oxidation. According to a recent review [Dambrova et al. 2021, Physiological Reviews], acylcarnitines (ACs) can be classified into 9 different categories depending on the type and size of their acyl-group: 1) short-chain ACs; 2) medium-chain ACs; 3) long-chain ACs; 4) very long-chain ACs; 5) hydroxy ACs; 6) branched chain ACs; 7) unsaturated ACs; 8) dicarboxylic ACs and 9) miscellaneous ACs. Short-chain ACs have acyl-groups with two to five carbons (C2-C5), medium-chain ACs have acyl-groups with six to thirteen carbons (C6-C13), long-chain ACs have acyl-groups with fourteen to twenty once carbons (C14-C21) and very long-chain ACs have acyl groups with more than 22 carbons. 2-hydroxy-3-methylbutanedioylcarnitine is therefore classified as a short chain AC. As a short-chain acylcarnitine 2-hydroxy-3-methylbutanedioylcarnitine is a member of the most abundant group of carnitines in the body, comprising more than 50\\% of all acylcarnitines quantified in tissues and biofluids (PMID: 31920980). Some short-chain carnitines have been studied as supplements or treatments for a number of diseases, including neurological disorders and inborn errors of metabolism. Carnitine acetyltransferase (CrAT, EC:2.3.1.7) is responsible for the synthesis of all short-chain and short branched-chain acylcarnitines (PMID: 23485643). The study of acylcarnitines is an active area of research and it is likely that many novel acylcarnitines will be discovered in the coming years. It is also likely that many novel roles in health and disease will be uncovered. An excellent review of the current state of knowledge for acylcarnitines is available at [Dambrova et al. 2021, Physiological Reviews].

Dmean

2-(1-{6-[(2-hydroxyethyl)(methyl)amino]naphthalen-2-yl}ethylidene)propanedinitrile

C18H17N3O (291.1371552)

methyl 5-acetamido-1,7-anhydro-3,5-dideoxy-beta-D-glycero-D-galacto-nonulopyranoside

C12H21NO7 (291.13179560000003)

benzosimuline

C19H17NO2 (291.1259222)

CHEMBL1162137

C18H17N3O (291.1371552)

Cys Val Ala

C11H21N3O4S (291.1252706)

Cys Ile Gly

C11H21N3O4S (291.1252706)

Ala Cys Val

C11H21N3O4S (291.1252706)

Ala Met Ala

C11H21N3O4S (291.1252706)

Cys Gly Ile

C11H21N3O4S (291.1252706)

Ala Val Cys

C11H21N3O4S (291.1252706)

Cys Ala Val

C11H21N3O4S (291.1252706)

Diphenhydramine Hydrochloride

Diphenhydramine HCl (Benadryl)

C17H22ClNO (291.13898320000004)

Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB)[1][2].