Exact Mass: 277.2769

Exact Mass Matches: 277.2769

Found 15 metabolites which its exact mass value is equals to given mass value 277.2769, within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error 0.001 dalton.

Perhexiline

(-)-2-(2,2-Dicyclohexylethyl)piperidine

C19H35N (277.2769)

Perhexiline is only found in individuals that have used or taken this drug. It is a coronary vasodilator used especially for angina of effort. It may cause neuropathy and hepatitis. [PubChem]Perhexiline binds to the mitochondrial enzyme carnitine palmitoyltransferase (CPT)-1 and CPT-2. It acts by shifting myocardial substrate utilisation from long chain fatty acids to carbohydrates through inhibition of CPT-1 and, to a lesser extent, CPT-2, resulting in increased glucose and lactate utilization. This results in increased ATP production for the same O2 consumption as before and consequently increases myocardial efficiency. C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent > C333 - Calcium Channel Blocker C - Cardiovascular system > C08 - Calcium channel blockers > C08E - Non-selective calcium channel blockers D002317 - Cardiovascular Agents > D002121 - Calcium Channel Blockers D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents D000077264 - Calcium-Regulating Hormones and Agents D049990 - Membrane Transport Modulators C93038 - Cation Channel Blocker

C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent > C333 - Calcium Channel Blocker C - Cardiovascular system > C08 - Calcium channel blockers > C08E - Non-selective calcium channel blockers D002317 - Cardiovascular Agents > D002121 - Calcium Channel Blockers D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents D000077264 - Calcium-Regulating Hormones and Agents D049990 - Membrane Transport Modulators C93038 - Cation Channel Blocker

Exact Mass: 277.2769

Exact Mass Matches: 277.2769

Perhexiline

CHEMBL14331

2-(5-Hexenyl)-3,4-dihydro-5-nonyl-2H-pyrrole

277A Lehmizidine

2-Hex-5-enyl-5-non-8-enyl-pyrrolidine

(2R,5R)-2-(pent-4-en-1-yl)-5-pentyldecahydroquinoline

(5R,6R,8R,8aR)-6,8-dimethyl-5-(non-8-en-1-yl)octahydroindolizine

1-methyl-4-(non-8-en-1-yl)octahydro-2H-quinolizine

(3R,5S)-5-methyl-3-(non-8-en-1-yl)octahydro-1H-pyrrolo[1,2-a]azepine

PERHEXILINE

(3r,5r,9ar)-5-methyl-3-(non-8-en-1-yl)-octahydro-1h-pyrrolo[1,2-a]azepine

2-(hex-1-en-1-yl)-5-nonyl-4,5-dihydro-1h-pyrrole

5-methyl-3-(non-8-en-1-yl)-octahydro-1h-pyrrolo[1,2-a]azepine

2-(hex-1-en-1-yl)-5-nonylidenepyrrolidine

(2s,5s)-2-(hex-5-en-1-yl)-5-(non-8-en-1-yl)pyrrolidine