Exact Mass: 276.0109

Exact Mass Matches: 276.0109

Found 81 metabolites which its exact mass value is equals to given mass value 276.0109, within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error 0.001 dalton.

4-Hydroxycyclophosphamide

Tetrahydro-2-(bis(2-chloroethyl)amino)-2H-1,3,2-oxazaphosphorin-4-ol 2-oxide

C7H15Cl2N2O3P (276.0197)


4-Hydroxycyclophosphamide is a primary activation metabolite of cyclophosphamide and of mafosfamide (an experimental drug) after they partially metabolized by cytochrome P450 (PMID: 12021633). Cyclophosphamide is a chemotherapeutic used to suppress the immune system and to treat several cancers including lymphoma, multiple myeloma, leukemia, ovarian cancer, breast cancer and small cell lung cancer. After cyclphosphamide is converted to 4-hydroxycyclophosphamide it is then partially tautomerized into aldophosphamide, which easily enters live cells whereupon it is partially detoxified into inactive carboxycyclophosphamide by the enzyme ALDH. 4-Hydroxycyclophosphamide is also an intermediate metabolite in the formation of phosphoramide mustard, the active metabolite, and acrolein, the metabolite responsible for much of the toxicity associated with cyclophosphamides (PMID: 7059981). 4-Hydroxycyclophosphamide is not cytotoxic at physiologic pH, readily diffuses into cells and spontaneously decomposes into the active phosphoramide mustard. In human liver microsomes, 4-Hydroxycyclophosphamide formation correlates with known phenotypic markers of CYP2B6 activity, specifically formation of (S)-2-ethyl-1,5-dimethyl-3,3-diphenyl pyrrolidine and hydroxybupropion. In addition, it is reported that the CYP2B6 genotype is not consistently related to 4-Hydroxycyclophosphamide formation in vitro or in vivo (PMID: 21976622). 4-Hydroxycyclophosphamide is only found in individuals who have consumed the drug cyclophosphamide. D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D009588 - Nitrogen Mustard Compounds D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D010752 - Phosphoramide Mustards

   

Aldophosphamide

Aldophosphamide

C7H15Cl2N2O3P (276.0197)


D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D009588 - Nitrogen Mustard Compounds D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D010752 - Phosphoramide Mustards

   

2-(2-chlorophenyl)-5-(5-methyl-2-thienyl)-1,3,4-oxadiazole

2-(2-Chloro-phenyl)-5-(5-methylthiophen-2-yl)-[1,3,4]oxadiazole

C13H9ClN2OS (276.0124)


   

4-Hydroxyifosfamide

3-(2-chloroethyl)-2-[(2-chloroethyl)amino]-4-hydroxy-1,3,2λ⁵-oxazaphosphinan-2-one

C7H15Cl2N2O3P (276.0197)


4-Hydroxyifosfamide is the active metabolite of the bifunctional alkylating cytostatic drug known as ifosfamide. 4-Hydroxyifosfamide is a member of the compound class known as oxazaphosphorines. Oxazaphosphorines are any saturated six-membered heterocycle containing three carbon atoms and one each of oxygen, nitrogen and phosphorus, especially one in which the phosphorus atom is linked to both the nitrogen and oxygen atoms. 4-Hydroxyifosfamide is very unstable in plasma and a stabilization procedure by adding citric acid has been developed (PMID: 9172103). 4-Hydroxyifosfamide is known to pass through the blood-brain barrier, and can reach cerebrospinal fluid concentrations that are almost as high as plasma concentrations (PMID: 9677448). 4-Hydroxyifosfamide is only found in individuals who have consumed or received the drug Ifosfamide. D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D009588 - Nitrogen Mustard Compounds D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D010752 - Phosphoramide Mustards

   

Aldoifosfamide

3-({bis[(2-chloroethyl)amino]phosphoryl}oxy)propanal

C7H15Cl2N2O3P (276.0197)


Aldoifosfamide is a metabolite of ifosfamide. Ifosfamide (pronounced eye. fos. fa. mide) (also marketed as Mitoxana and Ifex) is a nitrogen mustard alkylating agent used in the treatment of cancer. It is sometimes abbreviated IFO. (Wikipedia)

   

Menadione sodiuM bisulfite

Menadione sodiuM bisulfite

C11H9NaO5S (276.0068)


D006401 - Hematologic Agents > D003029 - Coagulants > D006490 - Hemostatics D050299 - Fibrin Modulating Agents > D000933 - Antifibrinolytic Agents D018977 - Micronutrients > D014815 - Vitamins

   

Aldophosphamide

3-({amino[bis(2-chloroethyl)amino]phosphoryl}oxy)propanal

C7H15Cl2N2O3P (276.0197)


Detoxification of cyclophosphamide is effected, in part, by hepatic class 1 aldehyde dehydrogenase (ALDH-1)-catalyzed oxidation of aldophosphamide, a pivotal aldehyde intermediate, to the nontoxic metabolite, carboxyphosphamide. Detoxification of aldophosphamide may also be effected by enzymes, viz. Thus, NAD-linked oxidation and NADPH-linked reduction of aldophosphamide catalyzed by relevant erythrocyte enzymes were quantified. (PMID: 9394035) Class 1 aldehyde dehydrogenases (ALDH-1) function as drug resistance gene products by catalyzing the irreversible conversion of aldophosphamide, an active metabolite of cyclophosphamide, to an inert compound. (PMID: 9322086) D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D009588 - Nitrogen Mustard Compounds D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D010752 - Phosphoramide Mustards

   

1,1-Bis(4-chlorophenyl)prop-2-yn-1-ol

1,1-Bis(4-chlorophenyl)prop-2-yn-1-ol

C15H10Cl2O (276.0109)


   

Trithiolaniacin

Trithiolaniacin

C14H12S3 (276.0101)


   

Phorate sulfoxide

Phorate sulfoxide

C7H17O3PS3 (276.0077)


   

Maybridge4_000845

Maybridge4_000845

C8H13BrN4S (276.0044)


   

1-(ethyldichlorosilyl)-2-(diethylchlorosilyl)ethane

1-(ethyldichlorosilyl)-2-(diethylchlorosilyl)ethane

C8H19Cl3Si2 (276.0091)


   

5-Amino-1-(3-bromophenyl)-3-methyl-1H-pyrazole-4-carbonitrile

5-Amino-1-(3-bromophenyl)-3-methyl-1H-pyrazole-4-carbonitrile

C11H9BrN4 (276.0011)


   

di(p-Nitrophenyl) sulfide

di(p-Nitrophenyl) sulfide

C12H8N2O4S (276.0205)


   

2,4,6-Tris(1-chloroethyl)-1,3,5-trioxane

2,4,6-Tris(1-chloroethyl)-1,3,5-trioxane

C9H15Cl3O3 (276.0087)


   

7-CHLOROMETHYL-3-PHENYL-THIAZOLO[3,2-A]PYRIMIDIN-5-ONE

7-CHLOROMETHYL-3-PHENYL-THIAZOLO[3,2-A]PYRIMIDIN-5-ONE

C13H9ClN2OS (276.0124)


   

(3-BROMOPHENYL)(P-TOLYL)METHANOL

(3-BROMOPHENYL)(P-TOLYL)METHANOL

C14H13BrO (276.015)


   

4,4-Dichlorochalcone

4,4-Dichlorochalcone

C15H10Cl2O (276.0109)


   

1-(bromomethyl)-4-(phenoxymethyl)benzene

1-(bromomethyl)-4-(phenoxymethyl)benzene

C14H13BrO (276.015)


   

3-(BENZO[D][1,3]DIOXOL-5-YL)-4-CHLOROBENZOIC ACID

3-(BENZO[D][1,3]DIOXOL-5-YL)-4-CHLOROBENZOIC ACID

C14H9ClO4 (276.0189)


   

3-CHLORO-[1,1-BIPHENYL]-3,4-DICARBOXYLIC ACID

3-CHLORO-[1,1-BIPHENYL]-3,4-DICARBOXYLIC ACID

C14H9ClO4 (276.0189)


   

3-CHLORO-[1,1-BIPHENYL]-4,4-DICARBOXYLIC ACID

3-CHLORO-[1,1-BIPHENYL]-4,4-DICARBOXYLIC ACID

C14H9ClO4 (276.0189)


   

5-TRIFLUOROMETHOXY-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER

5-TRIFLUOROMETHOXY-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER

C11H7F3O3S (276.0068)


   

1-(Benzyloxy)-2-(bromomethyl)benzene

1-(Benzyloxy)-2-(bromomethyl)benzene

C14H13BrO (276.015)


   

3-NITRO-4-(2-PYRIDYLTHIO)BENZOIC ACID

3-NITRO-4-(2-PYRIDYLTHIO)BENZOIC ACID

C12H8N2O4S (276.0205)


   

1-IODO-2-ISOPROPYL-4-METHOXYBENZENE

1-IODO-2-ISOPROPYL-4-METHOXYBENZENE

C10H13IO (276.0011)


   

2-(2,7-Dichloro-9H-fluoren-4-yl)oxirane

2-(2,7-Dichloro-9H-fluoren-4-yl)oxirane

C15H10Cl2O (276.0109)


   

Phosphoric acid,2,2-dichloroethenyl bis(1-methylethyl) ester

Phosphoric acid,2,2-dichloroethenyl bis(1-methylethyl) ester

C8H15Cl2O4P (276.0085)


   

2,2-(perfluorocyclohexa-2,5-diene-1,4-diylidene)dimalononitrile

2,2-(perfluorocyclohexa-2,5-diene-1,4-diylidene)dimalononitrile

C12F4N4 (276.0059)


   

5-amino-1-benzyl-2-bromoimidazole-4-carbonitrile

5-amino-1-benzyl-2-bromoimidazole-4-carbonitrile

C11H9BrN4 (276.0011)


   

Benzeneacetic acid,2,3,5,6-tetrafluoro-4-(trifluoromethyl)-

Benzeneacetic acid,2,3,5,6-tetrafluoro-4-(trifluoromethyl)-

C9H3F7O2 (276.0021)


   

Benzyl 2-bromo-4-methylphenyl ether

Benzyl 2-bromo-4-methylphenyl ether

C14H13BrO (276.015)


   

2-anthracenesulfonyl chloride

2-anthracenesulfonyl chloride

C14H9ClO2S (276.0012)


   

2,4,6-triethyl-1,3,5,2λ5,4λ5,6λ5-trioxatriphosphinane 2,4,6-trioxide

2,4,6-triethyl-1,3,5,2λ5,4λ5,6λ5-trioxatriphosphinane 2,4,6-trioxide

C6H15O6P3 (276.0081)


   

6-ETHYL-3-PYRIDINYL BORONIC ACID PINACOL ESTER

6-ETHYL-3-PYRIDINYL BORONIC ACID PINACOL ESTER

C14H13BrO (276.015)


   

1h,1h,2h,3h-nonafluorohept-2-en-1-ol

1h,1h,2h,3h-nonafluorohept-2-en-1-ol

C7H5F9O (276.0197)


   

3-Benzyloxybenzyl bromide

3-Benzyloxybenzyl bromide

C14H13BrO (276.015)


   

3-Bromo-5-(N-Boc)aminomethylisoxazole

3-Bromo-5-(N-Boc)aminomethylisoxazole

C9H13BrN2O3 (276.0109)


   

4-chloro-2-(4-chlorophenyl)-2H-chromene

4-chloro-2-(4-chlorophenyl)-2H-chromene

C15H10Cl2O (276.0109)


   

4-chloro-2-(2-chlorophenyl)-2H-chromene

4-chloro-2-(2-chlorophenyl)-2H-chromene

C15H10Cl2O (276.0109)


   

4-chloro-2-(3-chlorophenyl)-2H-chromene

4-chloro-2-(3-chlorophenyl)-2H-chromene

C15H10Cl2O (276.0109)


   

5-benzyloxy-2-bromotoluene

5-benzyloxy-2-bromotoluene

C14H13BrO (276.015)


   

1-naphthyl triflate

1-naphthyl triflate

C11H7F3O3S (276.0068)


   

2-Naphthyl trifluoromethanesulfonate

2-Naphthyl trifluoromethanesulfonate

C11H7F3O3S (276.0068)


   

N-BOC-5-(AMINOMETHYL)-3-BROMOISOXAZOLE

N-BOC-5-(AMINOMETHYL)-3-BROMOISOXAZOLE

C9H13BrN2O3 (276.0109)


   

1-(bromomethyl)-2-(phenoxymethyl)benzene

1-(bromomethyl)-2-(phenoxymethyl)benzene

C14H13BrO (276.015)


   

diethoxy-(ethylsulfinylmethylsulfanyl)-sulfanylidene-λ5-phosphane

diethoxy-(ethylsulfinylmethylsulfanyl)-sulfanylidene-λ5-phosphane

C7H17O3PS3 (276.0077)


   

methyl mercuric acetate

methyl mercuric acetate

C3H6HgO2 (276.0074)


   

1-((BENZYLOXY)METHYL)-3-BROMOBENZENE

1-((BENZYLOXY)METHYL)-3-BROMOBENZENE

C14H13BrO (276.015)


   

4-Benzyloxybenzyl bromide

4-Benzyloxybenzyl bromide

C14H13BrO (276.015)


   

2-[1-METHYL-3-(TRIFLUOROMETHYL)PYRAZOL-5-YL]-THIOPHENE-5-CARBOXYLIC ACID

2-[1-METHYL-3-(TRIFLUOROMETHYL)PYRAZOL-5-YL]-THIOPHENE-5-CARBOXYLIC ACID

C10H7F3N2O2S (276.018)


   

3-perfluorobutyl-1,2-epoxypropane

3-perfluorobutyl-1,2-epoxypropane

C7H5F9O (276.0197)


   

(6E)-6-[(2-chlorophenyl)methylidene]-7H-[1,3]thiazolo[3,2-a]pyrimidin-5-one

(6E)-6-[(2-chlorophenyl)methylidene]-7H-[1,3]thiazolo[3,2-a]pyrimidin-5-one

C13H9ClN2OS (276.0124)


   

(6E)-6-[(4-chlorophenyl)methylidene]-7H-[1,3]thiazolo[3,2-a]pyrimidin-5-one

(6E)-6-[(4-chlorophenyl)methylidene]-7H-[1,3]thiazolo[3,2-a]pyrimidin-5-one

C13H9ClN2OS (276.0124)


   

6-[(2-chlorophenyl)methyl]-[1,3]thiazolo[3,2-a]pyrimidin-5-one

6-[(2-chlorophenyl)methyl]-[1,3]thiazolo[3,2-a]pyrimidin-5-one

C13H9ClN2OS (276.0124)


   

6-[(4-chlorophenyl)methyl]-[1,3]thiazolo[3,2-a]pyrimidin-5-one

6-[(4-chlorophenyl)methyl]-[1,3]thiazolo[3,2-a]pyrimidin-5-one

C13H9ClN2OS (276.0124)


   

Benzyl 5-bromo-2-methylphenyl ether

Benzyl 5-bromo-2-methylphenyl ether

C14H13BrO (276.015)


   

4-(TERT-BUTYL)-2-IODOPHENOL

4-(TERT-BUTYL)-2-IODOPHENOL

C10H13IO (276.0011)


   

1-(3-Bromophenyl)piperazine hydrochloride (1:1)

1-(3-Bromophenyl)piperazine hydrochloride (1:1)

C10H14BrClN2 (276.0029)


   

3-(ACETYLAMINO)-4-HYDROXY-5-NITROBENZEN&

3-(ACETYLAMINO)-4-HYDROXY-5-NITROBENZEN&

C8H8N2O7S (276.0052)


   

2-Propen-1-one,3-(2-chlorophenyl)-1-(4-chlorophenyl)-

2-Propen-1-one,3-(2-chlorophenyl)-1-(4-chlorophenyl)-

C15H10Cl2O (276.0109)


   

(BICYCLO[2.2.1]HEPTA-2,5-DIENE)[(2S,3S)-BIS(DIPHENYLPHOSPHINO)-BUTANE]RHODIUM(I)PERCHLORATE

(BICYCLO[2.2.1]HEPTA-2,5-DIENE)[(2S,3S)-BIS(DIPHENYLPHOSPHINO)-BUTANE]RHODIUM(I)PERCHLORATE

C6H18Si2Te (276.0009)


   

2-(chloromethyl)-5-phenyl-3H-thieno[2,3-d]pyrimidin-4-one

2-(chloromethyl)-5-phenyl-3H-thieno[2,3-d]pyrimidin-4-one

C13H9ClN2OS (276.0124)


   

5-(1-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-3-YL)THIOPHENE-2-CARBOXYLIC ACID

5-(1-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-3-YL)THIOPHENE-2-CARBOXYLIC ACID

C10H7F3N2O2S (276.018)


   

5-AMINO-1-(4-BROMOPHENYL)-3-METHYL-4-CYANO 1H-PYRAZOLE

5-AMINO-1-(4-BROMOPHENYL)-3-METHYL-4-CYANO 1H-PYRAZOLE

C11H9BrN4 (276.0011)


   

1-(4-Bromophenyl)piperazine hydrochloride

1-(4-Bromophenyl)piperazine hydrochloride

C10H14BrClN2 (276.0029)


   

Menadionesodiumdisulfite

Menadionesodiumdisulfite

C11H9NaO5S (276.0068)


   

1,1-Bis(4-chlorophenyl)prop-2-yn-1-ol

1,1-Bis(4-chlorophenyl)prop-2-yn-1-ol

C15H10Cl2O (276.0109)


   

6-(4-Chlorophenyl)-4-(methylsulfanyl)-2-oxo-1,2-dihydro-3-pyridinecarbonitrile

6-(4-Chlorophenyl)-4-(methylsulfanyl)-2-oxo-1,2-dihydro-3-pyridinecarbonitrile

C13H9ClN2OS (276.0124)


   

N-(4,5-Dihydro-5-oxo-1,2-dithiolo[4,3-b]pyrrole-6-yl)benzamide

N-(4,5-Dihydro-5-oxo-1,2-dithiolo[4,3-b]pyrrole-6-yl)benzamide

C12H8N2O2S2 (276.0027)


   

3-(2-Methyloxiran-2-yl)propyl phosphono hydrogen phosphate

3-(2-Methyloxiran-2-yl)propyl phosphono hydrogen phosphate

C6H14O8P2 (276.0164)


   

N-acetyl-S-(2-succino)-L-cysteine

N-acetyl-S-(2-succino)-L-cysteine

C9H10NO7S-3 (276.0178)


   

alpha-(3-Phenoxyphenyl)ethyl bromide

alpha-(3-Phenoxyphenyl)ethyl bromide

C14H13BrO (276.015)


   

4-Hydroxycyclophosphamide

(R,S)-4-Hydroxy Cyclophosphamide

C7H15Cl2N2O3P (276.0197)


A phosphorodiamide that consists of 2-amino-1,3,2-oxazaphosphinan-4-ol 2-oxide having two 2-chloroethyl groups attached to the exocyclic nitrogen. D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D009588 - Nitrogen Mustard Compounds D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D010752 - Phosphoramide Mustards

   
   

4-Hydroxyifosfamide

4-Hydroxyifosfamide

C7H15Cl2N2O3P (276.0197)


D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D009588 - Nitrogen Mustard Compounds D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D010752 - Phosphoramide Mustards

   

2-(2-Chloro-phenyl)-5-(5-methylthiophen-2-yl)-[1,3,4]oxadiazole

2-(2-Chloro-phenyl)-5-(5-methylthiophen-2-yl)-[1,3,4]oxadiazole

C13H9ClN2OS (276.0124)


   

Hydroxycyclophosphamide

Hydroxycyclophosphamide

C7H15Cl2N2O3P (276.0197)


   

(3r,5s)-3,5-diphenyl-1,2,4-trithiolane

(3r,5s)-3,5-diphenyl-1,2,4-trithiolane

C14H12S3 (276.0101)


   

3-chloro-1,6-dihydroxy-8-methylxanthen-9-one

3-chloro-1,6-dihydroxy-8-methylxanthen-9-one

C14H9ClO4 (276.0189)


   

(2,3,4,5,6-pentahydroxycyclohexyl)oxyphosphonothioic acid

(2,3,4,5,6-pentahydroxycyclohexyl)oxyphosphonothioic acid

C6H13O8PS (276.0069)