Exact Mass: 273.0909
Exact Mass Matches: 273.0909
Found 118 metabolites which its exact mass value is equals to given mass value 273.0909,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
1,6-Dihydro-1-(3-methoxyphenethyl)-6-oxonicotinic acid
Modafinil
Modafinil is a stimulant drug marketed as a wakefulness promoting agent and is one of the stimulants used in the treatment of narcolepsy. Narcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing peptides, the orexins, whose neurons are activated by modafinil. The prexin neuron activation is associated with psychoactivation and euphoria. The exact mechanism of action is unclear, although in vitro studies have shown it to inhibit the reuptake of dopamine by binding to the dopamine reuptake pump, and lead to an increase in extracellular dopamine. Modafinil activates glutamatergic circuits while inhibiting GABA. N - Nervous system > N06 - Psychoanaleptics > N06B - Psychostimulants, agents used for adhd and nootropics > N06BA - Centrally acting sympathomimetics D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants > D064690 - Wakefulness-Promoting Agents D065693 - Cytochrome P-450 Enzyme Inducers > D065701 - Cytochrome P-450 CYP3A Inducers COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
L-Thyronine
Thyronine (T0) is a de-iodinated form of thyroxine. Thyronine are a group of metabolites derived from thyroxine and triiodothyronine via the peripheral enzymatic removal of iodines from the thyroxine nucleus. Thyronine is the thyroxine nucleus devoid of its four iodine atoms. Thyronine (T0) has been identified in human urine. In 22 normal individuals urinary thyronine concentrations were found to range between 8-25 nmol‚ÅÑ24h (PMID: 479355). Thyronine is thought to be a byproduct of thyroxine metabolism and arises through the action of thyroxine deiodinases. Iodide is actively absorbed from the bloodstream and concentrated in the thyroid follicles. (If there is a deficiency of dietary iodine, the thyroid enlarges in an attempt to trap more iodine, resulting in goitre.) Via a reaction with the enzyme thyroperoxidase, iodine is covalently bound to tyrosine residues in the thyroglobulin molecules, forming monoiodotyrosine (MIT) and diiodotyrosine (DIT). Linking two moieties of DIT produces thyroxine. Combining one particle of MIT and one particle of DIT produces triiodothyronine. D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
(2,5-Dioxopyrrolidin-1-yl) 5-(2-hydroxyethoxy)-4-oxopentanoate
Benzoic acid, 4-[[(2,5-dihydroxyphenyl)methyl]amino]-, methyl ester
5-Hydroxymethylcytidine
5-(Hydroxymethyl)cytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
provigil
N - Nervous system > N06 - Psychoanaleptics > N06B - Psychostimulants, agents used for adhd and nootropics > N06BA - Centrally acting sympathomimetics D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants > D064690 - Wakefulness-Promoting Agents D065693 - Cytochrome P-450 Enzyme Inducers > D065701 - Cytochrome P-450 CYP3A Inducers COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
methyl 5,5,5-trifluoro-4-(4-methylphenyl)iminopentanoate
methyl 5,5,5-trifluoro-4-(2-methylphenyl)iminopentanoate
methyl 5,5,5-trifluoro-4-(3-methylphenyl)iminopentanoate
(Meso-1R,5S,6R)-Ethyl 3-Benzyl-2,4-Dioxo-3-Azabicyclo[3.1.0]Hexane-6-Carboxylate
1-(3-FLUOROBENZYL)-4-PIPERIDINECARBOXYLICACIDHYDROCHLORIDE
1-Benzyl-3-trifluoromethyl-pyrrolidine-3-carboxylic acid
6-(ALLYLOXY)-1-ETHYL-4-OXO-1,4-DIHYDROQUINOLINE-2-CARBOXYLIC ACID
2-CYCLOHEXYL-1,3-DIOXO-2,3-DIHYDRO-1 H-ISOINDOLE-5-CARBOXYLIC ACID
5-Nitro-2-(3-piperidinylmethoxy)pyridinehydrochloride
Methoxypolyethylene glycol succinate N-hydroxysuccinimide
2-(tert-Butyl)-3-hydroxy-4-(trifluoromethyl)isoindolin-1-one
2-(tert-Butyl)-3-hydroxy-5-(trifluoromethyl)isoindolin-1-one
3-(4-Fluorophenyl)-5-(furan-2-yl)-4,5-dihydro-1H-pyrazole-1-carboxamide
1-tert-butoxycarbonylisoquinoline-3-carboxylic acid
1-(4-Trifluoromethylphenyl)piperidine-4-carboxylic acid
1-(4-FLUORO-BENZYL)-PIPERIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE
Ethyl morpholine-2-carboxylate 2,2,2-trifluoroacetate
(3-(N-isopropylsulfamoyl)-4-Methoxyphenyl)boronic acid
2-(tert-Butyl)-3-hydroxy-6-(trifluoromethyl)isoindolin-1-one
2-(2-Chlorophenyl)-1-[4-(dimethylamino)phenyl]ethanone
armodafinil
N - Nervous system > N06 - Psychoanaleptics > N06B - Psychostimulants, agents used for adhd and nootropics > N06BA - Centrally acting sympathomimetics D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants > D064690 - Wakefulness-Promoting Agents D065693 - Cytochrome P-450 Enzyme Inducers > D065701 - Cytochrome P-450 CYP3A Inducers C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant
1-Benzyl-4-trifluoromethyl-pyrrolidine-3-carboxylic acid
Pyrrole-2,4-dicarboxylic acid, 3,5-dimethyl-, 4-benzyl ester (7CI)
(R)-(+)-alpha-[(3-Methoxy-1-methyl-3-oxo-1-propenyl)amino]-1,4-cyclohexadiene-1-acetic acid sodium salt
4-METHYL-N-(4-METHYL-BENZYLIDENE)BENZENESULFONAMIDE
1,6-Dihydro-4-hydroxy-2-methyl-6-oxo-1-phenyl-3-pyridinecarboxylic acid ethyl ester
2-propenoic acid, 3-[2-[(3,5-dimethyl-4-isoxazolyl)methoxy
(2-{[1-Ethyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]methoxy}ethyl)amine hydrochloride
1-(4-METHOXY-2-NITROPHENYL)PIPERAZINE HYDROCHLORIDE
3-(1,2,3,4-TETRAHYDROQUINOLIN-2-YL)-2-(TRIFLUOROMETHYL) PROPIONIC ACID
N-(2-aminopyrimidin-5-yl)-2-methyl-5-nitrobenzamide
Benzoic acid, 4-[[(2,5-dihydroxyphenyl)methyl]amino]-, methyl ester
D000970 - Antineoplastic Agents > D020032 - Tyrphostins
4-(5-Methoxy-1,2-dimethyl-1h-indol-3-yl)thiazol-2-ylamine
BENZOIC ACID, p-((2,4,6-TRIAMINO-5-PYRIMIDINYL)AZO)-
N-[4-(2-pyridinyl)-2-thiazolyl]cyclopentanecarboxamide
1-[2-(3-Methoxyphenyl)ethyl]-6-oxo-1,6-dihydropyridine-3-carboxylic acid
2-[4-(aminomethyl)phenyl]-3,5,7,8-tetrahydro-4H-thiino[4,3-d]pyrimidin-4-one
(2S)-2-azaniumyl-3-[4-(4-hydroxyphenoxy)phenyl]propanoate
1-(4-Methoxyphenyl)-3-(6-methyl-2-pyridinyl)thiourea
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2,5-dimethyl-3-furamide
2-methyl-N-[(E)-(2-nitrophenyl)methylideneamino]pyrazole-3-carboxamide
4-[[2-Furanyl(oxo)methyl]amino]benzoic acid propan-2-yl ester
3-[1-(Carboxymethyl)-5-phenyl-2-pyrrolyl]propanoic acid
methyl (4Z)-4-(furan-2-ylmethylidene)-2-methyl-5-oxo-1-prop-2-enylpyrrole-3-carboxylate
3-(1,3-Benzoxazol-2-ylsulanyl)-5,5-dimethylcyclohex-2-en-1-one
(E)-3-(Ethoxycarbonylmethylene)-1-para-tolyl-2,5-pyrrolidinedione
SIB-1553A
SIB-1553A is an orally bioavailable nicotinic acetylcholine receptors (nAChRs) agonist, with selectivity for β4 subunit-containing nAChRs. SIB-1553A is also a selective neuronal nAChR ligand. SIB-1553A is a cognitive enhancer, and has therapeutic potential for the symptomatic treatment of Alzheimer’s disease and other cognitive disorders[1][2].
