Exact Mass: 259.0434
Exact Mass Matches: 259.0434
Found 140 metabolites which its exact mass value is equals to given mass value 259.0434,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Glucosamine 6-phosphate
Glucosamine 6-phosphate (CAS: 3616-42-0) is normally produced in endothelial cells via de novo glucosamine synthesis by the enzyme fructose-6-phosphate amidotransferase and the modulation of this pathway by hyperglycemia and glutamine. Glutamine-fructose-6-phosphate amidotransferase (GFAT) catalyzes the first committed step in the pathway for biosynthesis of hexosamines in mammals.It is a member of the N-terminal nucleophile class of amidotransferases, GFAT transfers the amino group from the L-glutamine amide to D-fructose 6-phosphate, producing glutamic acid and glucosamine 6-phosphate. As glucosamine inhibits endothelial nitric oxide synthesis it has important implications for impaired endothelium-dependent relaxation and vascular dysfunction in diabetes mellitus (PMID:11270676, 11842094). Glucosamine 6-phosphate is normally produced in endothelial cells via the de novo glucosamine synthesis by the enzyme fructose-6-phosphate amidotransferase and the modulation of this pathway by hyperglycemia and glutamine. glutamine-fructose-6-phosphate amidotransferase (GFAT) catalyzes the first committed step in the pathway for biosynthesis of hexosamines in mammals. A member of the N-terminal nucleophile class of amidotransferases, GFAT transfers the amino group from the L-glutamine amide to D-fructose 6-phosphate, producing glutamic acid and glucosamine 6-phosphate. As glucosamine inhibits endothelial nitric oxide synthesis it has important implications for impaired endothelium-dependent relaxation and vascular dysfunction in diabetes mellitus. (PMID 11270676, 11842094) [HMDB] Acquisition and generation of the data is financially supported in part by CREST/JST. KEIO_ID G021; [MS2] KO008968 KEIO_ID G021
Glucosamine-1P
Glucosamine-1P is a substrate of enzyme UDP-N-acetylglucosamine diphosphorylase [EC 2.7.7.23] (KEGG). [HMDB] Glucosamine-1P is a substrate of enzyme UDP-N-acetylglucosamine diphosphorylase [EC 2.7.7.23] (KEGG). KEIO_ID G065
N-Sulfo-D-glucosamine
N-Sulfo-D-glucosamine is a structurally altered form of N-acetyl-D-glucosamine (a polysaccharide found in animal tissues) by heparan sulfate N-deacetylase /N-sulfotransferase enzymes. No human references found [HMDB]
scyllo-Inosamine 4-phosphate
Aminofructose 6-phosphate
This compound belongs to the family of Pentose Phosphates. These are carbohydrate derivatives containing a pentose substituted by one or more phosphate groups.
D-Galactosamine 6-phosphate
A galactosamine phosphate that is D-galactosamine substituted at position 1 by a monophosphate group.
Glucosamine 6-sulfate
Glucosamine 6-sulfate is a naturally occurring compound present in many of the bodys tissues, and belongs to a class of compounds known as glycosaminoglycans (GAGs). Glucosamine 6-sulfate is being used in the treatment of arthritis. Glucosamine for arthritis products is usually formulated as the hydrochloride salt or glucosamine sulfate and often combined with chondroitin sulphate. It is notable that while both the hydrochloride salt and glucosamine sulfate are used in pharmaceutical preparations, glucosamine sulfate is thought to have a higher biological activity due to the presence of the sulfate. It should also be noted that there is a large cost difference between the two salts, with the hydrochloride salt being significantly less expensive. (PMID: 15925239) [HMDB] Glucosamine 6-sulfate is a naturally occurring compound present in many of the bodys tissues, and belongs to a class of compounds known as glycosaminoglycans (GAGs). Glucosamine 6-sulfate is being used in the treatment of arthritis. Glucosamine for arthritis products is usually formulated as the hydrochloride salt or glucosamine sulfate and often combined with chondroitin sulphate. It is notable that while both the hydrochloride salt and glucosamine sulfate are used in pharmaceutical preparations, glucosamine sulfate is thought to have a higher biological activity due to the presence of the sulfate. It should also be noted that there is a large cost difference between the two salts, with the hydrochloride salt being significantly less expensive. (PMID: 15925239).
3-(4-chloro-phenyl)-2-methyl-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one
(s)-3-amino-2-oxetanone p-toluenesulfonic acid salt
2-Hydroxy-3-nitro-[1,1-biphenyl]-3-carboxylic acid
2-(2,4-difluorophenyl)-5-(trifluoromethyl)pyridine
METHYL 2-METHOXY-4-[(METHYLSULFONYL)AMINO]-BENZOATE
2-(4-Aminophenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol
4-CHLORO-4-HYDROXY-3-METHOXY-[1,1-BIPHENYL]-3-CARBONITRILE
2-chloro-7-methyl-3-(5-methyl-1,2,4-oxadiazol-3-yl)quinoline
(R)-3-Amino-2-oxetanone p-toluenesulfonic acid salt
4-chloro-6-(4-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidine
6-Chloro-3H-spiro[isobenzofuran-1,4-piperidine] hydrochloride
5-Chloro-3H-spiro[isobenzofuran-1,4-piperidine] hydrochloride
4-oxo-4-[3-(trifluoromethyl)anilino]but-2-enoic acid
2-amino-5-methyl-4-(4-nitrophenyl)thiophene-3-carbonitrile
5-Methyl-2-[(2-nitrophenyl)amino]thiophene-3-carbonitrile
Methyl 6-methoxyformamido-4-chloropyridin-2-ylcarbamate
2-(3-aminophenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol
(4-chlorophenyl)(4-piperidyl)methanone hydrochloride
Benzaldehyde,4-[bis(2-chloroethyl)amino]-2-methyl-
8-chloro-1-oxido-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-1-ium-11-one
2-chloro-6-morpholin-4-yl-5-nitropyrimidin-4-amine
2-(chloromethyl)-4-[(4-chlorophenyl)methyl]morpholine
methyl 5-chloroindeno[1,2-b]pyridine-5-carboxylate
N-[(4S,6S)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl]acetamide
N-((4R,6S)-6-METHYL-7,7-DIOXIDO-5,6-DIHYDRO-4H-THIENO[2,3-B]THIOPYRAN-4-YL)ACETAMIDE
(5-Amino-2,3,4-trihydroxy-6-oxohexyl) dihydrogen phosphate
6-Fluoro-2-(2-methylphenyl)-1,2-benzothiazol-3-one
2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-(1H-pyrrol-2-yl)-
N-(7-chloro-4-quinazolinyl)-N-(2-furylmethyl)amine
2-[(4-Methoxyphenyl)sulfonyl-methylamino]acetic acid
(3,4-Dihydroxy-2-nitrophenyl)(phenyl)methanone
D002491 - Central Nervous System Agents > D018726 - Anti-Dyskinesia Agents > D000978 - Antiparkinson Agents D004791 - Enzyme Inhibitors > D065098 - Catechol O-Methyltransferase Inhibitors
Sn-glycero-3-phosphoserine
A glycerol 1-phosphoserine in which the glycero portion has R-configuration.
Glucosamine 6-Phosphate (closed ring, complete stereochemistry)
[(2R,3R,4R,5R,6S)-5-amino-3,4,6-trihydroxyoxan-2-yl]methyl dihydrogen phosphate
3-Amino-3-deoxy-beta-D-fructofuranose 6-phosphoric acid
3-(methylthio)-5-[4-(trifluoromethyl)phenyl]-1H-1,2,4-triazole
2-(4-Chlorophenyl)-5-(prop-2-enylamino)-4-oxazolecarbonitrile
2-(3-Chlorophenyl)-5-(prop-2-enylamino)-4-oxazolecarbonitrile
2-azaniumyl-2-deoxy-1-O-(hydroxyphosphinato)-alpha-D-galactopyranose
(5-Amino-3,4,6-trihydroxyoxan-2-yl)methyl dihydrogen phosphate
2-amino-2-deoxy-D-glucopyranose 6-phosphate
The pyranose form of D-glucosamine 6-phosphate.
alpha-D-glucosamine 6-phosphate
A 2-amino-2-deoxy-D-glucopyranose 6-phosphate that has an alpha-configuration at the anomeric position.
glycerol 1-phosphoserine
A L-serine derivative consisting of L-serine having a 1-glycerophospho group attached to the side-chain hydroxy function.
