Exact Mass: 254.9963
Exact Mass Matches: 254.9963
Found 62 metabolites which its exact mass value is equals to given mass value 254.9963,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Anagrelide
Anagrelide is only found in individuals that have used or taken this drug. It is a drug used for the treatment of essential thrombocytosis (ET; essential thrombocythemia). It also has been used in the treatment of chronic myeloid leukemia. [Wikipedia]The mechanism by which anagrelide reduces blood platelet count is still under investigation. Studies in patients support a hypothesis of dose-related reduction in platelet production resulting from a decrease in megakaryocyte hypermaturation. In blood withdrawn from normal volunteers treated with anagrelide, a disruption was found in the postmitotic phase of megakaryocyte development and a reduction in megakaryocyte size and ploidy. At therapeutic doses, anagrelide does not produce significant changes in white cell counts or coagulation parameters, and may have a small, but clinically insignificant effect on red cell parameters. Anagrelide inhibits cyclic AMP phosphodiesterase III (PDEIII). PDEIII inhibitors can also inhibit platelet aggregation. However, significant inhibition of platelet aggregation is observed only at doses of anagrelide higher than those required to reduce platelet count. L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents C78275 - Agent Affecting Blood or Body Fluid > C1327 - Antiplatelet Agent D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors D006401 - Hematologic Agents > D005343 - Fibrinolytic Agents D050299 - Fibrin Modulating Agents D002317 - Cardiovascular Agents
1-(2,4-dichlorophenyl)-2-(1h-1,2,4-triazol-1-yl)ethanone
PRP_M256
CONFIDENCE Transformation product, tentative ID (Level 2b); INTERNAL_ID 2404
anagrelide
L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents C78275 - Agent Affecting Blood or Body Fluid > C1327 - Antiplatelet Agent D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors D006401 - Hematologic Agents > D005343 - Fibrinolytic Agents D050299 - Fibrin Modulating Agents D002317 - Cardiovascular Agents
Creatine phosphate disodium salt
Phosphocreatine disodium, one of organic compounds known as alpha amino acids and derivatives, is a substrate for the determination of creatine kinase and used to regenerate ATP during skeletal muscle contraction[1]. Phosphocreatine disodium, one of organic compounds known as alpha amino acids and derivatives, is a substrate for the determination of creatine kinase and used to regenerate ATP during skeletal muscle contraction[1].
[3-(4-bromophenyl)-4,5-dihydro-1,2-oxazol-5-yl]methanol
methyl 1-(5-bromopyridin-3-yl)cyclopropane-1-carboxylate
1-(7-BROMO-2H-BENZO[B][1,4]OXAZIN-4(3H)-YL)ETHANONE
2,6-DICHLORO-4-[(DIMETHYLAMINO)METHYL]PHENOL HYDROCHLORIDE
(R)-METHYL 1-(4-BROMOPHENYL)AZIRIDINE-2-CARBOXYLATE
Brofoxine
C78272 - Agent Affecting Nervous System > C28197 - Antianxiety Agent
1-Chloro-5-methoxy-4-nitro-2-(trifluoromethyl)benzene
6-BROMO-1,2,3,4-TETRAHYDRO-QUINOLINE-3-CARBOXYLIC ACID
3-Bromo-1-oxa-8-azaspiro[4.5]decane hydrochloride (1:1)
4-CHLORO-2-METHOXY-6-(TRIFLUOROMETHYL)-3-PYRIDINEC
2-(4-CHLOROBENZENESULFONYL)-ETHYLAMINE HYDROCHLORIDE
1-(6-bromo-5-hydroxy-2,3-dihydroindol-1-yl)ethanone
Disodium (1-methyl-4-oxoimidazolidin-2-ylidene)phosphoramidate
sodium,2-chloro-4-[(4-oxocyclohexa-2,5-dien-1-ylidene)amino]phenolate
6-phosphonato-2-dehydro-3-deoxy-D-galactate(3-)
An organophosphate oxoanion that is a trianion obtained via deprotonation of the carboxy and phosphate OH groups of 6-phospho-2-dehydro-3-deoxy-D-galactonic acid; major species at pH 7.3.
2-dehydro-3-deoxy-6-phosphonato-D-gluconate(3-)
An organophosphate oxoanion that is a trianion arising from deprotonation of the carboxylic acid and phosphate groups of 2-dehydro-3-deoxy-6-phospho-D-gluconic acid.
4-methylumbelliferone sulfate(1-)
An organosulfate oxoanion that is the conjugate base of 4-methylumbelliferone sulfate, obtained by deprotonation of the sulfo group; major species at pH 7.3.
