Exact Mass: 245.0812

Exact Mass Matches: 245.0812

Found 10 metabolites which its exact mass value is equals to given mass value 245.0812, within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error 8.0E-6 dalton.

5-Deoxy-5-fluorocytidine

C9H12FN3O4 (245.0812)

5'-Deoxy-5-fluorocytidine

4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-1,2-dihydropyrimidin-2-one

C9H12FN3O4 (245.0812)

5-Deoxy-5-fluorocytidine is a metabolite of capecitabine. Capecitabine (Xeloda, Roche) is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. Capecitabine is a prodrug, that is enzymatically converted to 5-fluorouracil in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue. (Wikipedia)

5-Fluoro-2'-deoxycytidine

4-amino-5-fluoro-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one

C9H12FN3O4 (245.0812)

2'-Deoxy-2'-fluorocytidine

4-amino-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

C9H12FN3O4 (245.0812)

5-DFCR (Deoxy-5-fluorocytidine)

4-amino-1-(3,4-dihydroxy-5-methyloxolan-2-yl)-5-fluoro-1,2-dihydropyrimidin-2-one

C9H12FN3O4 (245.0812)

2-Deoxy-5-fluorcytidine

5-Fluoro-2-deoxycytidine

C9H12FN3O4 (245.0812)

C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C272 - Antimetabolite 5-Fluoro-2'-deoxycytidine, a fluoropyrimidine nucleoside analogue, is a DNA methyltransferase (DNMT) inhibitor. 5-Fluoro-2'-deoxycytidine is a tumor-selective proagent of the potent thymidylate synthase inhibitor 5-fluoro-2′-dUMP[1][2].

2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine can act synergistically with T705 to increase the potency of both compounds antiviral effects on CCHFV replication[1].

Cytidine, 2-deoxy-5-fluoro-

C9H12FN3O4 (245.0812)