Exact Mass: 245.0147
Exact Mass Matches: 245.0147
Found 327 metabolites which its exact mass value is equals to given mass value 245.0147,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Guanfacine
A centrally acting antihypertensive agent. The drug lowers both systolic and diastolic blood pressure by activating the central nervous system alpha-2 adrenoreceptors, which results in reduced sympathetic outflow leading to reduced vascular tone. Its adverse reactions include dry mouth, sedation, and constipation. [PubChem] C - Cardiovascular system > C02 - Antihypertensives > C02A - Antiadrenergic agents, centrally acting > C02AC - Imidazoline receptor agonists C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
CHLORPHENESIN CARBAMATE
C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist
4-Hydroxyclonidine
4-Hydroxyclonidine is a metabolite of Clonidine. Clonidine (trade name Kapvay or Nexiclon) is a sympatholytic medication used to treat high blood pressure, ADHD, anxiety/panic disorder, and certain pain conditions. It is classified as a centrally acting α2 adrenergic agonist. An alternative hypothesis that has been proposed is that clonidine acts centrally as an imidazoline receptor agonist. (Wikipedia)
Lamivudine sulfoxide
Lamivudine sulfoxide is a metabolite of nitazoxanide. Nitazoxanide, also known by the brand names Alinia and Annita (and by Daxon, Dexidex, Kidonax, Mitafar, Pacovanton, and Paramix in Mexico, by Nitax, Zox, Nitazox, Niazid and Toza in Bangladesh) is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent. Nitazoxanide is a light yellow crystalline powder. It is poorly soluble in ethanol and practically insoluble in water. (Wikipedia)
3'-thiacytidine
4-(N,N-Dimethylaminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole
1-Cyano-N-[4-(trifluoromethoxy)phenyl]formohydrazide
8-(isocyanatomethyl)-[1,3]dioxolo[4,5-g]chromen-6-one
5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid
5-[(THIOPHEN-2-YLMETHYL)-AMINO]-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE
METHYL 5-BROMO-1-METHYL-6-OXO-1,6-DIHYDROPYRIDINE-3-CARBOXYLATE
2-[4-(4-nitrophenyl)-1,3-thiazol-2-yl]acetonitrile
1,5,6-trimethyl-1,2,3,4-tetrahydro-2lambda6-thieno[2,3-C][1,2]thiazine-2,2,4-trione
(6-FLUORO-4-(TRIFLUOROMETHYL)QUINOLIN-2-YL)METHANOL
2-(METHYLTHIO)-4-(PHENYLAMINO)PYRIMIDINE-5-CARBALDEHYDE
Methyl 3-amino-5-bromo-2-hydroxybenzenecarboxylate
Methyl 4-chloro-3-methoxy-5-nitrobenzenecarboxylate
2,4-dichloro-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
8-Methoxy-6-nitro-4-oxo-1,4-dihydro-3-quinolinecarbonitrile
3-AMINO-3-(3-CHLORO-4-HYDROXY-5-METHOXY-PHENYL)-PROPIONIC ACID
methyl 3-amino-6-bromo-5-methylpyrazine-2-carboxylate
4-AMINO-2-BENZYLSULFANYL-PYRIMIDINE-5-CARBALDEHYDE
1-(4-CHLOROPHENYL)-2,2,2-TRIFLUOROETHANAMINE HYDROCHLORIDE
2H-Indol-2-one, 6-chloro-5-(2-chloro-1-hydroxyethyl)-1,3-dihydro
4-[4-(trifluoromethyl)phenyl]thiadiazol-5-amine
1H-Pyrrole-2-carboxylic acid, 4-bromo-3,5-dimethyl-, ethyl ester
(4-chloro-2-fluoro-phenyl)-carbaMic acid tert-butyl ester
4-CHLORO-9-METHYL-2,9-DIHYDRO-1H-CARBAZOLE-3-CARBALDEHYDE
7-Methoxy-6-nitro-4-oxo-1,4-dihydro-3-quinolinecarbonitrile
5-[(Ethoxycarbonyl)amino]-1,2,4-thiadiazole-3-acetic acid methyl ester
1,3,5-Benzenetriamine, 2-methyl-, trihydrochloride
Methyl 6-Bromo-1,2-dihydro-2-oxo-4-pyridineacetate
CARBONIC ACID 4-NITROPHENYL ESTER 1-CHLORO-ETHYL ESTER
6-Methoxy-7-nitro-4-oxo-1,4-dihydro-3-quinolinecarbonitrile
4-Chloro-2-methoxy-5-nitro-benzoic acid methyl ester
4-ISOTHIOCYANATO-1,5-DIMETHYL-2-PHENYL-1,2-DIHYDRO-PYRAZOL-3-ONE
1,2,3,4-TETRAHYDRO-6,7-ISOQUINOLINEDIOL HYDROBROMIDE
4-(4-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-pyrimidinamine
4-(6-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-pyrimidinamine
2-Amino-5-[2-(trifluoromethyl)phenyl]-1,3,4-thiadiazole
5,6-Dihydro-4H-thieno[3,2-d][1]benzazepine-2-carboxylicacid
4-[2-(Trifluoromethyl)phenyl]-4H-1,2,4-triazole-3-thiol
(3-(N-(2-Hydroxyethyl)sulfamoyl)phenyl)boronic acid
(2-AMINO-4-(ETHOXYCARBONYL)PHENYL)BORONIC ACID HYDROCHLORIDE
Methyl 5,7-dichloropyrazolo[1,5-a]pyrimidine-3-carboxylate
n-(dithiocarboxy)sarcosine, disodium salt, dihydrate
(Z)-2-(2-Aminothiazol-4-yl)-2-carboxymethoxyiminoacetic acid
3-Benzyl-7-chloro-3H-[1,2,3]triazolo[4,5-d]pyrimidine
4-Amino-1-[(2S,5R)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone
(R)-1-(6-Chloro-2-methylsulfanyl-pyrimidin-4-yl)-pyrrolidin-3-ol
(4R)-2-(2,5-Difluorophenyl)-1,3-thiazolidine-4-carboxylic acid
(S)-1-(6-Chloro-2-methylsulfanyl-pyrimidin-4-yl)-pyrrolidin-3-ol
Magnesium aspartate hydrochloride hydrate
C4H5MgNO4.HCl.3(H2O) (245.0153)
4-HYDROXY-7-METHOXY-6-NITROQUINOLINE-3-CARBONITRILE
3-amino-1,2-benzene dicarboxylic acid,1-ethylester
N-[2-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)ethyl]-N,N-dimethylamine
n-fluoro-5-(trifluoromethyl)pyridinium-2-sulfonate
4-CHLORO-2-(1-METHYL-4-PIPERAZINYL)-5-THIAZOLECARBOXALDEHYDE
5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
Pyridoxal 5-phosphate(2-)
COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
2-[3-(Trifluoromethyl)phenyl]-4-isothiazoline-3-one
2-[2-(3,4-Dihydroxyphenyl)ethenyl]-6-hydroxy-pyran-4-one
(4R)-2-(1H-indol-3-yl)-4,5-dihydrothiazole-4-carboxylate
2-Amino-4-[(phosphonomethyl)hydroxy-phosphinyl]butanoate
4-amino-1-[4-hydroxy-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
1-Amino-3-(4-chloro-2-methoxy-5-methylphenyl)thiourea
9-methyl-6H-benzo[c][1,2]benzothiazine 5,5-dioxide
2-[(2-Furanylmethylthio)methyl]imidazo[1,2-a]pyrimidine
2-(4-amino-2,6-dichloroanilino)-4,5-dihydro-1H-imidazol-1-ium
GUANFACINE
C - Cardiovascular system > C02 - Antihypertensives > C02A - Antiadrenergic agents, centrally acting > C02AC - Imidazoline receptor agonists C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
Pyridoxal 5-phosphate(2-)
The dianion resulting from the removal of two protons from the phosphate group of pyridoxal 5-phosphate.
hispidin(1-)
An organic anion that is the conjugate base of hispidin resulting from the deprotonation of the 4-hydroxy group; major species at pH 7.3.
7-Chlorokynurenic acid (sodium salt)
7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid sodium salt is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid sodium salt has potent antinociceptive actions after neuraxial delivery[1][2].
LY367385 (hydrochloride)
LY367385 hydrochloride is a highly selective and potent mGluR1a antagonist. LY367385 hydrochloride has an IC50 of 8.8 μM for inhibiting of quisqualate-induced phosphoinositide (PI) hydrolysis, compared with >100 μM for mGlu5a. LY367385 hydrochloride has neuroprotective, anticonvulsant and antiepileptic effects[1][2].
