Exact Mass: 236.0619

Exact Mass Matches: 236.0619

Found 23 metabolites which its exact mass value is equals to given mass value 236.0619, within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error 4.0E-5 dalton.

Zileuton

(+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea

C11H12N2O2S (236.0619)


Leukotrienes are substances that induce numerous biological effects including augmentation of neutrophil and eosinophil migration, neutrophil and monocyte aggregation, leukocyte adhesion, increased capillary permeability, and smooth muscle contraction. These effects contribute to inflammation, edema, mucus secretion, and bronchoconstriction in the airways of asthmatic patients. Zileuton relieves such symptoms through its selective inhibition of 5-lipoxygenase, the enzyme that catalyzes the formation of leukotrienes from arachidonic acid. Specifically, it inhibits leukotriene LTB4, LTC4, LTD4, and LTE4 formation. Both the R(+) and S(-) enantiomers are pharmacologically active as 5-lipoxygenase inhibitors in in vitro systems. D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D020024 - Leukotriene Antagonists D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D004791 - Enzyme Inhibitors > D016859 - Lipoxygenase Inhibitors D002491 - Central Nervous System Agents > D000700 - Analgesics C471 - Enzyme Inhibitor > C1322 - Lipooxygenase Inhibitor D000893 - Anti-Inflammatory Agents D018501 - Antirheumatic Agents Zileuton is a potent and selective inhibitor of 5-lipoxygenase with antiasthmatic properties.

   

Maybridge1_006219

Maybridge1_006219

C11H12N2O2S (236.0619)


   

ZILEUTON

ZILEUTON

C11H12N2O2S (236.0619)


D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D020024 - Leukotriene Antagonists D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D004791 - Enzyme Inhibitors > D016859 - Lipoxygenase Inhibitors D002491 - Central Nervous System Agents > D000700 - Analgesics C471 - Enzyme Inhibitor > C1322 - Lipooxygenase Inhibitor D000893 - Anti-Inflammatory Agents D018501 - Antirheumatic Agents Zileuton is a potent and selective inhibitor of 5-lipoxygenase with antiasthmatic properties.

   

Zyflo

N-(1-benzo[b]thien-2-ylethyl)-N-hydroxy-urea

C11H12N2O2S (236.0619)


D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D020024 - Leukotriene Antagonists D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D004791 - Enzyme Inhibitors > D016859 - Lipoxygenase Inhibitors D002491 - Central Nervous System Agents > D000700 - Analgesics C471 - Enzyme Inhibitor > C1322 - Lipooxygenase Inhibitor D000893 - Anti-Inflammatory Agents D018501 - Antirheumatic Agents Zileuton is a potent and selective inhibitor of 5-lipoxygenase with antiasthmatic properties.

   

ETHYL 1-METHYL-5-THIEN-2-YL-1H-PYRAZOLE-3-CARBOXYLATE

ETHYL 1-METHYL-5-THIEN-2-YL-1H-PYRAZOLE-3-CARBOXYLATE

C11H12N2O2S (236.0619)


   

Thiourea,N,N-bis(2-furanylmethyl)-

Thiourea,N,N-bis(2-furanylmethyl)-

C11H12N2O2S (236.0619)


   

3-(Pyrrolidin-1-ylsulfonyl)benzonitrile

3-(Pyrrolidin-1-ylsulfonyl)benzonitrile

C11H12N2O2S (236.0619)


   

3-(2-hydroxypropyl)-2-sulfanylidene-1H-quinazolin-4-one

3-(2-hydroxypropyl)-2-sulfanylidene-1H-quinazolin-4-one

C11H12N2O2S (236.0619)


   

4-(2,5-DIMETHOXY-PHENYL)-THIAZOL-2-YLAMINE

4-(2,5-DIMETHOXY-PHENYL)-THIAZOL-2-YLAMINE

C11H12N2O2S (236.0619)


   

6-Amino-N-methyl-2-naphthalenesulfonamide

6-Amino-N-methyl-2-naphthalenesulfonamide

C11H12N2O2S (236.0619)


   

2-(1H-Benzoimidazol-2-ylsulfanyl)-butyric acid

2-(1H-Benzoimidazol-2-ylsulfanyl)-butyric acid

C11H12N2O2S (236.0619)


   

3-Cyano-N-(cyclopropylmethyl)benzenesulfonamide

3-Cyano-N-(cyclopropylmethyl)benzenesulfonamide

C11H12N2O2S (236.0619)


   

3-(1-METHYL-1H-BENZOIMIDAZOL-2-YLSULFANYL)-PROPIONIC ACID

3-(1-METHYL-1H-BENZOIMIDAZOL-2-YLSULFANYL)-PROPIONIC ACID

C11H12N2O2S (236.0619)


   

4-Imidazolidinone,5-(1-hydroxyethyl)-3-phenyl-2-thioxo-

4-Imidazolidinone,5-(1-hydroxyethyl)-3-phenyl-2-thioxo-

C11H12N2O2S (236.0619)


   

2-METHYL-1-TOSYL-1H-IMIDAZOLE

2-METHYL-1-TOSYL-1H-IMIDAZOLE

C11H12N2O2S (236.0619)


   
   

2-Thiazolamine,4-(3,4-dimethoxyphenyl)-

2-Thiazolamine,4-(3,4-dimethoxyphenyl)-

C11H12N2O2S (236.0619)


   

4-(2,4-DIMETHOXY-PHENYL)-THIAZOL-2-YLAMINE

4-(2,4-DIMETHOXY-PHENYL)-THIAZOL-2-YLAMINE

C11H12N2O2S (236.0619)


   

3-(3-HYDROXYPROPYL)-2-MERCAPTOQUINAZOLIN-4(3H)-ONE

3-(3-HYDROXYPROPYL)-2-MERCAPTOQUINAZOLIN-4(3H)-ONE

C11H12N2O2S (236.0619)


   

ETHYL 1-METHYL-3-THIEN-2-YL-1H-PYRAZOLE-5-CARBOXYLATE

ETHYL 1-METHYL-3-THIEN-2-YL-1H-PYRAZOLE-5-CARBOXYLATE

C11H12N2O2S (236.0619)


   

Methyl 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate

Methyl 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate

C11H12N2O2S (236.0619)


   

ethyl 4-methyl-2-(1H-pyrrol-1-yl)-1,3-thiazole-5-carboxylate

ethyl 4-methyl-2-(1H-pyrrol-1-yl)-1,3-thiazole-5-carboxylate

C11H12N2O2S (236.0619)


   

2-(Ethylthio)-5-(4-methoxyphenyl)-1,3,4-oxadiazole

2-(Ethylthio)-5-(4-methoxyphenyl)-1,3,4-oxadiazole

C11H12N2O2S (236.0619)