Exact Mass: 225.9693
Exact Mass Matches: 225.9693
Found 5 metabolites which its exact mass value is equals to given mass value 225.9693,
within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error
0.0002 dalton.
Oltipraz
Oltipraz is a dithiole derivative and a schistosomicide. The studies have show oltipraz is also a chemoprotector, an antocarcinogen and possibly an antimutagen. [PubMed: 9593327] D000890 - Anti-Infective Agents > D000998 - Antiviral Agents > D018894 - Reverse Transcriptase Inhibitors D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000871 - Anthelmintics D004791 - Enzyme Inhibitors > D019384 - Nucleic Acid Synthesis Inhibitors C1892 - Chemopreventive Agent > C54629 - Phase I Enzymes Inhibitor C1892 - Chemopreventive Agent > C54630 - Phase II Enzymes Inducer D020011 - Protective Agents > D016588 - Anticarcinogenic Agents C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor D000970 - Antineoplastic Agents Oltipraz has an inhibitory effect on HIF-1α activation in a time-dependent manner, completely abrogating HIF-1α induction at ≥10 μM concentrations, the IC50 of Oltipraz for HIF-1α inhibition is 10 μM. Oltipraz is a potent Nrf2 activator.
Oltipraz
D000890 - Anti-Infective Agents > D000998 - Antiviral Agents > D018894 - Reverse Transcriptase Inhibitors D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000871 - Anthelmintics D004791 - Enzyme Inhibitors > D019384 - Nucleic Acid Synthesis Inhibitors C1892 - Chemopreventive Agent > C54629 - Phase I Enzymes Inhibitor C1892 - Chemopreventive Agent > C54630 - Phase II Enzymes Inducer D020011 - Protective Agents > D016588 - Anticarcinogenic Agents C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor D000970 - Antineoplastic Agents Oltipraz has an inhibitory effect on HIF-1α activation in a time-dependent manner, completely abrogating HIF-1α induction at ≥10 μM concentrations, the IC50 of Oltipraz for HIF-1α inhibition is 10 μM. Oltipraz is a potent Nrf2 activator.
