Exact Mass: 192.0011

Exact Mass Matches: 192.0011

Found 2 metabolites which its exact mass value is equals to given mass value 192.0011, within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error 4.0E-5 dalton.

L-2-Hydroxyglutaric acid disodium

L-2-Hydroxyglutaric acid disodium

C5H6Na2O5 (192.0011)


L-2-Hydroxyglutaric acid disodium is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid disodium can inhibit histone demethylases and hence promote histone methylation[1]. L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity with Km and Ki of 2.52 mM and 11.13 mM, respectively[2].

   

α-Hydroxyglutaric acid (disodium)

α-Hydroxyglutaric acid (disodium)

C5H6Na2O5 (192.0011)


α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid disodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases[1].