Exact Mass: 192.0011

Exact Mass Matches: 192.0011

Found 2 metabolites which its exact mass value is equals to given mass value 192.0011, within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error 8.0E-6 dalton.

L-2-Hydroxyglutaric acid disodium

L-2-Hydroxyglutaric acid disodium

C5H6Na2O5 (192.0011)


L-2-Hydroxyglutaric acid disodium is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid disodium can inhibit histone demethylases and hence promote histone methylation[1]. L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity with Km and Ki of 2.52 mM and 11.13 mM, respectively[2].

   

α-Hydroxyglutaric acid (disodium)

α-Hydroxyglutaric acid (disodium)

C5H6Na2O5 (192.0011)


α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid disodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases[1].