Exact Mass: 175.1128
Exact Mass Matches: 175.1128
Found 130 metabolites which its exact mass value is equals to given mass value 175.1128,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Debrisoquine
Debrisoquine is an adrenergic neuron-blocking drug. Genetic and environmental factors are determinants of the interindividual and interethnic variability in drug metabolism. Thus, interethnic differences in debrisoquine hydroxylation polymorphism (Cytochrome p450, subfamily IID, polypeptide 6, CYP2D6) might be partly responsible for the variation in haloperidol disposition between races. The influence of tobacco, ethanol, caffeine, gender, and oral contraceptive use on the debrisoquine metabolic ratio (MR) has been analyzed in panels of healthy volunteers. About 5-10\\% of European white population has a genetically determinant defect of the CYP2D6, one of the enzymes of cytochrome P-450. This defect leads to the impaired metabolism of many drugs including various psychopharmacological agents. The measurement of the hydroxylation of debrisoquine is a laboratory test which allows identifying such an individual. Patients who show an impaired hydroxylation of debrisoquine usually demonstrate severe side effects and poor outcome of psychopharmacotherapy. In practice, knowledge of a patients debrisoquine metabolic phenotype is an advantage when prescribing tricyclic antidepressants and neuroleptics, as the drug concentration will be considerably higher in slow metabolisers than in the average patient. (PMID: 8839686, 1738265, 7878155) [HMDB] Debrisoquine is an adrenergic neuron-blocking drug. Genetic and environmental factors are determinants of the interindividual and interethnic variability in drug metabolism. Thus, interethnic differences in debrisoquine hydroxylation polymorphism (Cytochrome p450, subfamily IID, polypeptide 6, CYP2D6) might be partly responsible for the variation in haloperidol disposition between races. The influence of tobacco, ethanol, caffeine, gender, and oral contraceptive use on the debrisoquine metabolic ratio (MR) has been analyzed in panels of healthy volunteers. About 5-10\\% of European white population has a genetically determinant defect of the CYP2D6, one of the enzymes of cytochrome P-450. This defect leads to the impaired metabolism of many drugs including various psychopharmacological agents. The measurement of the hydroxylation of debrisoquine is a laboratory test which allows identifying such an individual. Patients who show an impaired hydroxylation of debrisoquine usually demonstrate severe side effects and poor outcome of psychopharmacotherapy. In practice, knowledge of a patients debrisoquine metabolic phenotype is an advantage when prescribing tricyclic antidepressants and neuroleptics, as the drug concentration will be considerably higher in slow metabolisers than in the average patient. (PMID: 8839686, 1738265, 7878155). C - Cardiovascular system > C02 - Antihypertensives > C02C - Antiadrenergic agents, peripherally acting > C02CC - Guanidine derivatives C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D013565 - Sympatholytics D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents COVID info from COVID-19 Disease Map ATC code: C02CC04 Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
L-argininium(1+)
L-argininium(1+), also known as L-Arginine or DL Arginine acetate, monohydrate, is classified as a member of the L-alpha-amino acids. L-alpha-amino acids are alpha amino acids which have the L-configuration of the alpha-carbon atom. L-argininium(1+) is considered to be soluble (in water) and acidic
4-(Dimethylamino)butyl carbamimidothioate
D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D017442 - Histamine Agonists
Debrisoquin
C - Cardiovascular system > C02 - Antihypertensives > C02C - Antiadrenergic agents, peripherally acting > C02CC - Guanidine derivatives C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D013565 - Sympatholytics D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents COVID info from COVID-19 Disease Map ATC code: C02CC04 Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
Pyrido[3,2-e]pyrrolo[1,2-a]pyrazine, 5,6,6a,7,8,9-hexahydro- (9CI)
N-METHYL-N-[(3-METHYL-1,2,4-OXADIAZOL-5-YL)METHYL]AMINE
PYRIDO[4,3-D]PYRIMIDINE, 2-CYCLOPROPYL-5,6,7,8-TETRAHYDRO-
2-Ethyl-5,7-Dimethyl-3H-Imidazo[4,5-B]Pyridine
Adenosine receptor antagonist 4 (compound 2) is an adenosine A1 receptor antagonist with a Ki of 101 nM for human A1 receptor[1].
methyl-(7-methyl-imidazo[1,2-a]pyridin-2-ylmethyl)-amine
1-(1H-BENZO[D]IMIDAZOL-2-YL)-N,N-DIMETHYLMETHANAMINE
1H-Benzimidazole-2-methanamine,alpha,1-dimethyl-(9CI)
2-BICYCLO[2.2.1]HEPT-2-YL-ETHYLAMINE HYDROCHLORIDE
methyl-(8-methyl-imidazo[1,2-a]pyridin-2-ylmethyl)-amine
1H-Benzimidazole-2-methanamine,alpha,5-dimethyl-(9CI)
2-(2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)ethanamine
METHYL-(5-METHYL-IMIDAZO[1,2-A]PYRIDIN-2-YLMETHYL)-AMINE
1-(1,5-dimethyl-1H-indazol-3-yl)methanamine(SALTDATA: FREE)
N-methyl-1-(1-methylbenzimidazol-2-yl)methanamine
2-(4-methyl-1H-benzimidazol-2-yl)ethanamine dihydrochloride
N-METHYL-N-[(1-METHYL-1H-INDAZOL-3-YL)METHYL]AMINE
1H-Imidazo[4,5-b]pyridine,7-methyl-2-(1-methylethyl)-(9CI)
L-argininium(1+)
L-argininium(1+), also known as L-Arginine or DL Arginine acetate, monohydrate, is classified as a member of the L-alpha-amino acids. L-alpha-amino acids are alpha amino acids which have the L-configuration of the alpha-carbon atom. L-argininium(1+) is considered to be soluble (in water) and acidic COVID info from WikiPathways, PDB, Protein Data Bank Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
(3S)-5-{[amino(iminio)methyl]amino}-3-ammoniopentanoate
(2S,4S,5S,6S)-4-(dimethylamino)-6-methyloxane-2,5-diol
(2S,4R,5R,6S)-4-(dimethylamino)-6-methyloxane-2,5-diol
(2s,3r,4s,6r)-4-(dimethylamino)-6-methyloxane-2,3-diol
α-1-c-ethyl-fagomine
{"Ingredient_id": "HBIN015323","Ingredient_name": "\u03b1-1-c-ethyl-fagomine","Alias": "NA","Ingredient_formula": "C8H17NO3","Ingredient_Smile": "CCC1CC(C(C(N1)CO)O)O","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "7436","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
