Exact Mass: 1680.660538
Exact Mass Matches: 1680.660538
Found 4 metabolites which its exact mass value is equals to given mass value 1680.660538,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Plecanatide
C65H104N18O26S4 (1680.6251684000001)
A - Alimentary tract and metabolism > A06 - Drugs for constipation > A06A - Drugs for constipation D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones D005765 - Gastrointestinal Agents > D000074268 - Guanylyl Cyclase C Agonists C78276 - Agent Affecting Digestive System or Metabolism D020536 - Enzyme Activators Plecanatide, an analogue of Uroguanylin, is an orally active guanylate cyclase-C (GC-C) receptor agonist. Plecanatide activates GC-C receptors to stimulate cGMP synthesis with an EC50 of 190 nM in T84 cells assay. Plecanatide shows anti-inflammatory activity in models of murine colitis[1][2][3].
Dolcanatide
C65H104N18O26S4 (1680.6251684000001)
Dolcanatide is an orally active GC-C (guanylate cyclase-C) agonist. Dolcanatide shows laxative, anti-nociceptive and anti-inflammatory activity. Dolcanatide can be used in inflammatory bowel disease research[1][2].