Exact Mass: 161.0874

Tryptophol, also known as indole-3-ethanol, is an indolyl alcohol that is ethanol substituted by a 1H-indol-3-yl group at position 2. It has a role as a Saccharomyces cerevisiae metabolite, an auxin and a plant metabolite. Tryptophol is a catabolite of tryptophan converted by the gut microbiota. After absorption through the intestinal epithelium, tryptophan catabolites enter the bloodstream and are later excreted in the urine (PMID:30120222). Tryptophol production was negatively associated with interferon-gamma production (IFNγ) which suggests that tryptophol has anti-inflammatory properties (PMID:27814509). Tryptophol has also been identified as the hypnotic agent in trypanosomal sleeping sickness, and because it is formed in vivo after ethanol or disulfiram treatment, it is also associated with the study of alcoholism (PMID:7241135). Indole-3-ethanol is a dietary indole present in cruciferous vegetables that has been shown to influence estradiol metabolism in humans and may provide a new chemopreventive approach to estrogen-dependent diseases. (PMID 2342128) Tryptophol. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=526-55-6 (retrieved 2024-06-29) (CAS RN: 526-55-6). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0). Tryptophol (Indole-3-ethanol) is an endogenous metabolite. Tryptophol (Indole-3-ethanol) is an endogenous metabolite.

Ethiolate

(R)-Boschniakine

(R)-6,7-Dihydro-7-methyl-5H-2-pyrindine-4-carboxaldehyde

(R)-Boschniakine is found in fruits. (R)-Boschniakine is an alkaloid from Plantago psyllium (African plantain

6-methylthiohexanaldoxime

1-(2,3-Dihydro-1H-pyrrolizin-5-yl)-2-propen-1-one

Proline-derived Maillard product. Proline-derived Maillard product

3-[(5-Methyl-2-furanyl)methyl]-1H-pyrrole

Putative proline-derived Maillard product formed in model reactions with 1-pyrroline and 5-methylfurfural. Putative proline-derived Maillard product formed in model reactions with 1-pyrroline and 5-methylfurfural

3,4-Dihydro-4-[(5-methyl-2-furanyl)methylene]-2H-pyrrole

(4Z)-4-[(5-methylfuran-2-yl)methylidene]-3,4-dihydro-2H-pyrrole

Putative proline-derived Maillard product formed in model reactions with proline or 1-pyrroline and 5-methylfurfural. Putative proline-derived Maillard product formed in model reactions with proline or 1-pyrroline and 5-methylfurfural

Amino (2S)-2,5-diamino-5-oxopentanoate

Amino (2S)-2,5-diamino-5-oxopentanoic acid

Tryptophol

5-21-03-00061 (Beilstein Handbook Reference)

An indolyl alcohol that is ethanol substituted by a 1H-indol-3-yl group at position 2. Tryptophol (Indole-3-ethanol) is an endogenous metabolite. Tryptophol (Indole-3-ethanol) is an endogenous metabolite.

Tryptophanol (not validated)

Annotation level-2

Indole-3-ethanol

5-Acryloyl-2,3-dihydro-1H-pyrrolizine

1-(2,3-Dihydro-1H-pyrrolizin-5-yl)-2-propen-1-one

3-(5-Methylfurfuryl)pyrrole

3-[(5-Methyl-2-furanyl)methyl]-1H-pyrrole

A diarylmethane in which the two aryl groups are specified as 5-methylfuran-2-yl and pyrrol-3-yl.

3-(5-Methylfurfurylidene)-1-pyrroline

(4Z)-4-[(5-methylfuran-2-yl)methylidene]-3,4-dihydro-2H-pyrrole

BENZONITRILE, 2-(1-METHYLETHOXY)-

1-Acetylindoline

(1-Methyl-1H-indazol-6-yl)Methanamine

1-Pyridin-2-yl-cyclobutanecarbaldehyde

1-Benzyl-3-oxoazetidine

2-(2-methoxyphenyl)ethylisocyanide

3-Methyl-7,8-dihydroquinolin-5(6H)-one

2-Propenamide,2-methyl-N-phenyl-

2,4,6-TRIMETHYLPHENYL ISOCYANATE

1H-Indole-2-methanol,1-methyl-

6-Ethoxy-1H-indole

1-(2-Chloropropyl)piperidine

5-Ethoxy-1H-indole

4-methoxy-2-methyl-1H-indole

N-(4-VINYL-PHENYL)-ACETAMIDE

4-Methyl-3,4-dihydro-1(2H)-isoquinolinone

2-Ethoxyphenylacetonitrile

3-(N-Phenyl-N-methyl)aminoacrolein

3-(methoxymethyl)-1H-indole

5-Phenyl-2-pyrrolidinone

Cyclopropanecarboxamide,1-phenyl-

(S)-(-)-1-PHENYLPROPYL ISOCYANATE

1H-Benzimidazol-2-amine,N,5-dimethyl-(9CI)

1-(INDOLIN-7-YL)ETHANONE

2,3-Dihydro-2-Methyl-4(1H)-Quinolinone

1-(2-isocyanoethyl)-4-methoxybenzene

(1-Methyl-1H-indazol-4-yl)Methanamine

Benzenamine, 4-(4,5-dihydro-1H-imidazol-2-yl)-

1H-Indol-4-ol,1-ethyl-(9CI)

2,5,6-trimethylbenzoxazole

4-amino-6-hydroxy-2-methylpyrimidine dihydrate

C-(2-METHYL-IMIDAZO[1,2-A]PYRIDIN-3-YL)-METHYLAMINE

2-Propoxybenzonitrile

3-(4-Methoxyphenyl)propionitrile

7-ethoxy-1H-indole

1H-Indole-3-ethanol, radical ion(1+)

N-Benzylacrylamide

2-Imidazo[1,2-a]pyridin-2-ylethanamine

4,5-dimethyl-1H-benzimidazol-6-amine(SALTDATA: 2HCl)

2-Ethyl-1H-indol-4-ol

1H-Indole-1-ethanol

4-ISOPROPOXYBENZONITRILE

6-Methoxy-4-methyl-1H-indole

(8-methylimidazo[1,2-a]pyridin-2-yl)methanamine

(4-Methyl-1H-indol-3-yl)methanol

N,N-Dimethyl-1H-indazol-5-amine

2,3-dimethylimidazo[1,2-a]pyridin-8-amine

hexane-1,3,6-tricarbonitrile

1-(1h-benzoimidazol-2-yl)-ethylamine

3-[(4-pyridylmethyl)amino]propanenitrile

4-METHOXY-1-METHYL-1H-INDOLE

2,3,4,5-Tetrahydro-1H-2-benzazepin-1-one

IMIDAZO[1,2-A]PYRIDIN-3-YLMETHYL-METHYL-AMINE

4-Isopropylphenylisocyanate

2-(1H-PYRROLO[3,2-B]PYRIDIN-3-YL)ETHANAMINE

3-Ethyl-1H-indazol-5-amine

2-Methoxy-4,6-dimethylbenzonitrile

5-methyl-3,4-dihydroisoquinolin-1(2H)-one

5,7-DIMETHYLINDOLIN-2-ONE

1H-Benzimidazol-2-amine,N,1-dimethyl-(9CI)

2-(1H-benzimidazol-4-yl)ethanamine

4-methoxy-2,3-dimethylbenzonitrile

BENZONITRILE,4-HYDROXY-2-ISOPROPYL

2-(1H-Indazol-3-yl)ethanamine

7-Methoxy-2-methyl-1H-indole

1-Ethyl-1H-indazol-5-amine

1-Methylindoline-5-carboxaldehyde 97

(4-Amino-phenyl)-cyclopropylmethanone

6-Amino-3,4-dihydro-1(2H)-naphthalenone

6-Amino-1,2,3,4-tetrahydronaphthalen-1-one

N-(2,3-dihydro-1H-inden-2-yl)formamide

α-benzyl-β-hydroxypropionitrile

N-FORMYL-1,2,3,4-TETRAHYDROISOQUINOLINE

Phenylpyrrolidone

1-Phenyl-2-pyrrolidinone (1-Phenylpyrrolidin-2-one) is a phenyl analogue of GABA with sedative effect, decreasing the exploratory behavior of rats at 50-100 mg/kg (i.v.). 1-Phenyl-2-pyrrolidinone also has been proved to inhibit emotional reactions in dogs and cats. 1-Phenyl-2-pyrrolidinone induces decreases in the pressor reaction to emotional stress without accompanied by normalization of the function of baroreceptor reflexes[1][2].

5-Acetylindoline,1-(2,3-dihydro-1H-indol-5-yl)ethanone

4-Phenyl-2-pyrrolidinone

L-TERT-LEUCINEMETHYLESTERHYDROCHLORIDE

5-Methoxy-2-methylindole

5-Methoxy-2-methyl-1H-indole

2H-Indol-2-one,3-ethyl-1,3-dihydro-

(1-methyl-1h-benzimidazol-2-yl)methylamine

4-Methoxy-3,5-dimethylbenzonitrile

4-Ethoxy-1H-indole

4,7-Dimethyl-1-Isoindolinone

IMidazo[1,2-a]pyridine-6-Methanamine, 3-Methyl-

1-(1H-indazol-4-yl)ethanamine

2-ethyl-6-methylphenyl isocyanate

ENIPORIDE

5-Amino-3,4-dihydro-1(2H)-naphthalenone

Diallyldimethylammonium chloride

4,5-Dihydro-1H-benzo[d]azepin-2(3H)-one

1,2,3,4-Tetrahydrobenzo[b]azepin-5-one

1-ETHYL-1H-BENZO[D]IMIDAZOL-2-AMINE

(1H-BENZOIMIDAZOL-2-YLMETHYL)METHYLAMINE

1-Benzofuran-2-yl-ethylamine

5,6-DIMETHYL-1H-BENZO[D]IMIDAZOL-7-AMINE

6-Methoxy-7-methyl-1H-indole

1H-Benzimidazole-2-methanamine,alpha-methyl-,(R)-(9CI)

5-METHOXY-1-METHYL1H-INDOLE

8-METHYL-3,4-DIHYDROQUINOLIN-2(1H)-ONE

2-Ethyl-4-methyl-1,3-benzoxazole

2-HYDROXY-4-(1-METHYLETHYL)-BENZONITRILE

1H-Benzimidazol-4-amine,1-ethyl-

7-Methoxy-3,4-dihydroisoquinoline

6-METHYL-2,3-DIHYDROQUINOLIN-4(1H)-ONE

Benzonitrile,2,4,6-trimethyl-, N-oxide

2-(4-hydroxyphenyl)-2-methylpropanenitrile

1-Cyclopropyl-2-(2-pyridinyl)ethanone

1-Cyclopropyl-2-(3-pyridinyl)ethanone

2-PROPYLPHENYL ISOCYANATE

4-(2-PYRIDYL)-2-METHYL-3-BUTYN-2-OL

3-isocyanatopropylbenzene

1H-Benzimidazole-1-ethanamine(9CI)

2-Amino-5,7-dimethylbenzimidazole

N,N-dimethyl-1H-pyrrolo[2,3-d]pyridin-6-amine

5-METHOXY-4-METHYLINDOLE

1H-Benzimidazol-1-amine,5,6-dimethyl-(9CI)

1-(2-CHLOROETHYL) HEXAMETHYLENIMINE

1-(IMIDAZO[1,2-A]PYRIDIN-2-YL)-N-METHYLMETHANAMINE

(3-aminophenyl)-cyclopropylmethanone

2-(IMIDAZO[1,2-A]PYRIDIN-3-YL)ETHANAMINE

(5-methyl-1H-indol-3-yl)methanol

1-phenylpyrrolidin-3-one

3,3-Dimethylindolin-2-one

2-ethyl-3H-benzimidazol-5-amine

2-Ethyl-2H-indazol-5-amine

1H-Benzimidazol-2-amine,4,5-dimethyl-(9CI)

Benzonitrile, 3-amino-4-(ethylamino)- (9CI)

7-Amino-3,4-dihydro-1(2H)-naphthalenone

O-isobutyl ethylthiocarbamate

1H-Benzimidazol-5-amine,1,2-dimethyl-(9CI)

2-(1H-Benzo[d]imidazol-2-yl)ethanamine

1H-Benzimidazol-1-amine,4,7-dimethyl-(9CI)

2,3-Dimethyl-1H-pyrrolo[2,3-b]pyridin-6-amine

2-Ethyl-1H-pyrrolo[2,3-b]pyridin-3-amine

4,6-Dimethyl-1H-pyrrolo[2,3-b]pyridin-3-amine

2-Ethyl-1H-pyrrolo[2,3-b]pyridin-5-amine

5-Methoxy-6-methyl-1H-indole

6-METHYL-3,4-DIHYDROISOQUINOLIN-1(2H)-ONE

6-Methoxy-5-methyl-1H-indole

1H-Indene-2-carboxamide,2,3-dihydro-(9CI)

3-(3-hydroxypropyl)benzonitrile

3-ethyl-4-hydroxy-5-methylbenzonitrile

1,2-dimethylindol-5-ol

3-Amino-4,5-dihydro-1-phenylpyrazole

N-(IMIDAZO[1,2-A]PYRIDIN-6-YLMETHYL)-N-METHYLAMINE

(1-Methyl-1H-indol-5-yl)methanol

2-(1H-Pyrrolo[3,2-c]pyridin-3-yl)ethanamine

2-(3-METHOXYPHENYL)ETHYLISOCYANIDE

5,6-DIMETHYL-2,3-DIHYDRO-ISOINDOL-1-ONE

5,6-Dimethyl-1H-benzimidazol-2-amine

3-(pyridin-3-ylmethylamino)propanenitrile

2-(4-methoxy-3-methylphenyl)acetonitrile

3-Methoxy-4-methylphenylacetonitrile

3-ETHOXYPHENYLACETONITRILE

(4-Methoxy-2-methylphenyl)acetonitrile

4-propoxybenzonitrile

Trimethylsilyl N,N-dimethylcarbamate

C6H15NO2Si (161.0872)

1H-Benzimidazole-2-methanamine,alpha-methyl-(9CI)

Spiro[2.5]octan-6-amine(6CI)

2-(3-methoxy-5-methylphenyl)acetonitrile

3-Ethyl-4-Hydroxymethyl-Benzonitrile

3-azabicyclo[3.2.2]nonane hydrochloride

5-ethyl-1,3-dihydroindol-2-one

3-methyl-2,3-dihydroindole-1-carbaldehyde

3,4-DIHYDRO-1-METHOXYISOQUINOLINE

alpha-Methylimidazo[1,2-a]pyridine-6-methanamine

1-benzylazetidin-2-one

2-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethanamine

2-methyl-4-pyridin-4-ylbut-3-yn-2-ol

Cis-Hexahydroisoindole Hydrochloride

4,5-Dihydro-1H-benzo[b]azepin-2(3H)-one

3-Buten-2-one,4-phenyl-, oxime

3,4-Dihydronaphthalen-1(2H)-one oxime

2-benzo[b]furan-3-ylethylamine

2,3-Dimethyl-2H-indazol-6-amine

7-methyl-3,4-dihydro-2h-isoquinolin-1-one

2-Isopropylphenyl isocyanate

(4-Ethoxyphenyl)acetonitrile

(1-METHYL-1H-INDOL-4-YL)METHANOL

2-(1H-benzo[d]imidazol-1-yl)ethanamine

(4S)-4-Phenyl-2-pyrrolidinone

3-Azabicyclo[3.3.1]nonane hydrochloride

2-PYRIDIN-2-YLCYCLOPENTANONE

4-CYCLOPROPYLPIPERIDINE HYDROCHLORIDE

5-Methoxy-3-methyl-1H-indole

L-Glutamic acid,5-hydrazide

4-(3-Hydroxypropyl)benzonitrile

5-Methoxy-7-methyl-1H-indole

(R)-1-PHENYLPROPYL ISOCYANATE

1-Methyl-3,4-dihydro-1H-quinolin-2-one

4-METHYLPHENOXYPROPIONITRILE

1-ethylindazol-3-amine

1H-Benzimidazol-5-amine,1-ethyl-(9CI)

1-(3-chloropropyl)piperidine

2-(5-Amino-2-pyridyl)-2-methylpropanenitrile

1H-Benzimidazol-4-amine,N,N-dimethyl

2-(Isopropylamino)nicotinonitrile

N-(1-PHENYL-VINYL)-ACETAMIDE

8-Amino-3,4-dihydro-1H-naphthalen-2-one

(1-Methyl-1H-indazol-3-yl)methanamine

8-amino-3,4-dihydro-2H-naphthalen-1-one

(2-METHOXY-1-METHYL-ETHYL)-(4-METHYLSULFANYL-BENZYL)-AMINE

N-ethyl-1H-pyrrolo[2,3-b]pyridin-6-amine

1H-Benzimidazol-1-amine,4,5-dimethyl-(9CI)

2-ETHYL-6-METHYL-IMIDAZO[1,2-B]PYRIDAZINE

1,3-Dimethyl-1H-indazol-5-amine

1H-Benzimidazol-2-amine,4,7-dimethyl-(9CI)

2,5,7-trimethylpyrazolo[1,5-a]pyrimidine

3-(Benzyloxy)propionitrile

1-(1H-BENZOIMIDAZOL-2-YL)-3-METHYLSULFANYL-PROPYLAMINE

(1-Methyl-1H-indol-6-yl)methanol

2-Ethyl-5-Methylbenzoxazole

4-Methoxy-6-methyl-1H-indole

5,7-DIMETHYL-2,3-DIHYDRO-ISOINDOL-1-ONE

cyclopropyl-(2-methylpyridin-4-yl)methanone

Methyl 4-fluoro-4-piperidinecarboxylate

C7H12FNO2 (161.0852)

2-(1H-Pyrrolo[2,3-c]pyridin-3-yl)ethanamine

Azoxybacilin