Exact Mass: 1421.7489

Exact Mass Matches: 1421.7489

Found 18 metabolites which its exact mass value is equals to given mass value 1421.7489, within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error 0.01 dalton.

Bacitracin

(4R)-4-[(2S)-2-{[(4R)-2-[(1S,2S)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazol-4-yl]formamido}-4-methylpentanamido]-4-{[(1S,2S)-1-{[(3S,6R,9S,12R,15S,18R,21S)-18-(3-aminopropyl)-12-benzyl-15-[(2S)-butan-2-yl]-3-(carbamoylmethyl)-6-(carboxymethyl)-9-(1H-imidazol-4-ylmethyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclopentacosan-21-yl]carbamoyl}-2-methylbutyl]carbamoyl}butanoic acid

C66H103N17O16S (1421.7489)


Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy. Its unique name derives from the fact that the bacillus producing it was first isolated in 1943 from a knee scrape from a girl named Margaret Tracy. As a toxic and difficult-to-use antibiotic, bacitracin doesnt work well orally. However, it is very effective topically. Bacitracin is synthesised via the so-called nonribosomal peptide synthetases (NRPSs), which means that ribosomes are not involved in its synthesis. C254 - Anti-Infective Agent > C258 - Antibiotic > C295 - Bacitracin D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents Bacitracin is a polypeptide antibiotic against staphylococcal and pathogenic protozoa infections. Bacitracin inhibits cell wall biosynthesis and permeability through binding to the undecaprenyl pyrophosphate. Bacitracin inhibits macromolecular synthesis. Bacitracin is also a protein disulfide isomerase (PDI) inhibitor[1][2][3].

   

Bacitracin A

(4R)-4-{[(2S)-2-[({2-[(1S)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazol-5-yl}(hydroxy)methylidene)amino]-1-hydroxy-4-methylpentylidene]amino}-4-{[(1S)-1-{[(3S,6R,9S,12R,15S,18R,21S)-18-(3-aminopropyl)-12-benzyl-15-(butan-2-yl)-6-(carboxymethyl)-2,5,8,11,14,17,20-heptahydroxy-3-[(C-hydroxycarbonimidoyl)methyl]-9-[(1H-imidazol-5-yl)methyl]-1,4,7,10,13,16,19-heptaazacyclopentacosa-1,4,7,10,13,16,19-heptaen-21-yl]-C-hydroxycarbonimidoyl}-2-methylbutyl]-C-hydroxycarbonimidoyl}butanoate

C66H103N17O16S (1421.7489)


Bacitracin A is a permitted food additive for animal and human consumption. Permitted food additive for animal and human consumption

   

Apelin-12 (human, bovine, mouse, rat)

2-({1-[2-({1-[2-(6-amino-2-{2-[2-(2-{2-[(1-{2-amino-5-[(diaminomethylidene)amino]pentanoyl}pyrrolidin-2-yl)formamido]-5-[(diaminomethylidene)amino]pentanamido}-4-methylpentanamido)-3-hydroxypropanamido]-3-(1H-imidazol-5-yl)propanamido}hexanamido)acetyl]pyrrolidin-2-yl}formamido)-4-(methylsulfanyl)butanoyl]pyrrolidin-2-yl}formamido)-3-phenylpropanoic acid

C64H103N21O14S (1421.7714)


   

Baciguent

4-(2-{[2-(1-amino-2-methylbutyl)-4,5-dihydro-1,3-thiazol-4-yl]formamido}-4-methylpentanamido)-4-[(1-{[18-(3-aminopropyl)-12-benzyl-15-(butan-2-yl)-3-(carbamoylmethyl)-6-(carboxymethyl)-9-[(1H-imidazol-5-yl)methyl]-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclopentacosan-21-yl]carbamoyl}-2-methylbutyl)carbamoyl]butanoic acid

C66H103N17O16S (1421.7489)


D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents

   

Bacitracin

Bacitracin

C66H103N17O16S (1421.7489)


Bacitracin is a polypeptide antibiotic against staphylococcal and pathogenic protozoa infections. Bacitracin inhibits cell wall biosynthesis and permeability through binding to the undecaprenyl pyrophosphate. Bacitracin inhibits macromolecular synthesis. Bacitracin is also a protein disulfide isomerase (PDI) inhibitor[1][2][3].

   
   
   

Apelin-12

H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH

C64H103N21O14S (1421.7714)


Apelin-12 is one of the most potent C-terminal fragments of the polypeptide that possesses a high affinity to orphan receptor APJ receptor. Apelin-12 is involved in the regulation of body fluid homeostasis and in the central control of feeding. Apelin-12 blocks HIV-1 entry through APJ receptor. Apelin-12 exerts neuroprotective effect[1][2][3].

   
   

(4R)-4-[[(2S)-2-[[(4R)-2-[(1S,2S)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazole-4-carbonyl]amino]-4-methylpentanoyl]amino]-5-[[(2S,3S)-1-[[(3S,6R,9S,12R,15S,18R,21R)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-12-benzyl-15-[(2S)-butan-2-yl]-6-(carboxymethyl)-9-(1H-imidazol-5-ylmethyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclopentacos-21-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid

(4R)-4-[[(2S)-2-[[(4R)-2-[(1S,2S)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazole-4-carbonyl]amino]-4-methylpentanoyl]amino]-5-[[(2S,3S)-1-[[(3S,6R,9S,12R,15S,18R,21R)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-12-benzyl-15-[(2S)-butan-2-yl]-6-(carboxymethyl)-9-(1H-imidazol-5-ylmethyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclopentacos-21-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid

C66H103N17O16S (1421.7489)


   

Bacitracin F, 1-(N-((2-(1-amino-2-methylbutyl)-4,5-dihydro-4-thiazolyl)carbonyl)-L-leucine)-

Bacitracin F, 1-(N-((2-(1-amino-2-methylbutyl)-4,5-dihydro-4-thiazolyl)carbonyl)-L-leucine)-

C66H103N17O16S (1421.7489)


   
   

(4R)-4-[[(2S)-2-[[2-(1-amino-2-methylbutyl)-4,5-dihydro-1,3-thiazole-4-carbonyl]amino]-4-methylpentanoyl]amino]-5-[[(2S)-1-[[(3S,6R,9S,12R,15S,18R,21S)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-12-benzyl-15-butan-2-yl-6-(carboxymethyl)-9-(1H-imidazol-5-ylmethyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclopentacos-21-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid

(4R)-4-[[(2S)-2-[[2-(1-amino-2-methylbutyl)-4,5-dihydro-1,3-thiazole-4-carbonyl]amino]-4-methylpentanoyl]amino]-5-[[(2S)-1-[[(3S,6R,9S,12R,15S,18R,21S)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-12-benzyl-15-butan-2-yl-6-(carboxymethyl)-9-(1H-imidazol-5-ylmethyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclopentacos-21-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid

C66H103N17O16S (1421.7489)


   

Unk-Leu-D-Glu-xiIle-Lys(1)-D-Orn-Ile-D-Phe-His-D-Asp-Asn-(1)

Unk-Leu-D-Glu-xiIle-Lys(1)-D-Orn-Ile-D-Phe-His-D-Asp-Asn-(1)

C66H103N17O16S (1421.7489)


   

Bacitracin A

Bacitracin A

C66H103N17O16S (1421.7489)


A homodetic cyclic peptide consisting of (4R)-2-[(1S,2S)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazole-4-carboxylic acid attached head-to-tail to L-leucyl,D-glutamyl, L-lysyl, D-ornityl, L-isoleucyl, D-phenylalanyl, L-histidyl. D-aspartyl and L-asparaginyl residues coupled in sequence and cyclised by condensation of the side-chain amino group of the L-lysyl residue with the C-terminal carboxylic acid group. It is the major component of bacitracin. C254 - Anti-Infective Agent > C258 - Antibiotic > C295 - Bacitracin

   

(4s)-4-{[(2s)-2-({[(4r)-2-[(1r,2r)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazol-4-yl](hydroxy)methylidene}amino)-1-hydroxy-4-methylpentylidene]amino}-4-{[(1r,2s)-1-{[(3r,6r,9r,12r,15r,18r,21r)-18-(3-aminopropyl)-12-benzyl-15-[(2r)-butan-2-yl]-6-(carboxymethyl)-2,5,8,11,14,17,20-heptahydroxy-3-(c-hydroxycarbonimidoylmethyl)-9-(3h-imidazol-4-ylmethyl)-1,4,7,10,13,16,19-heptaazacyclopentacosa-1,4,7,10,13,16,19-heptaen-21-yl]-c-hydroxycarbonimidoyl}-2-methylbutyl]-c-hydroxycarbonimidoyl}butanoic acid

(4s)-4-{[(2s)-2-({[(4r)-2-[(1r,2r)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazol-4-yl](hydroxy)methylidene}amino)-1-hydroxy-4-methylpentylidene]amino}-4-{[(1r,2s)-1-{[(3r,6r,9r,12r,15r,18r,21r)-18-(3-aminopropyl)-12-benzyl-15-[(2r)-butan-2-yl]-6-(carboxymethyl)-2,5,8,11,14,17,20-heptahydroxy-3-(c-hydroxycarbonimidoylmethyl)-9-(3h-imidazol-4-ylmethyl)-1,4,7,10,13,16,19-heptaazacyclopentacosa-1,4,7,10,13,16,19-heptaen-21-yl]-c-hydroxycarbonimidoyl}-2-methylbutyl]-c-hydroxycarbonimidoyl}butanoic acid

C66H103N17O16S (1421.7489)


   

(4r)-4-{[(2s)-2-[({2-[(1s)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazol-5-yl}(hydroxy)methylidene)amino]-1-hydroxy-4-methylpentylidene]amino}-4-{[(1s)-1-{[(3s,6r,9s,12r,15s,18r,21s)-18-(3-aminopropyl)-12-benzyl-6-(carboxymethyl)-2,5,8,11,14,17,20-heptahydroxy-3-(c-hydroxycarbonimidoylmethyl)-9-(3h-imidazol-4-ylmethyl)-15-(sec-butyl)-1,4,7,10,13,16,19-heptaazacyclopentacosa-1,4,7,10,13,16,19-heptaen-21-yl]-c-hydroxycarbonimidoyl}-2-methylbutyl]-c-hydroxycarbonimidoyl}butanoic acid

(4r)-4-{[(2s)-2-[({2-[(1s)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazol-5-yl}(hydroxy)methylidene)amino]-1-hydroxy-4-methylpentylidene]amino}-4-{[(1s)-1-{[(3s,6r,9s,12r,15s,18r,21s)-18-(3-aminopropyl)-12-benzyl-6-(carboxymethyl)-2,5,8,11,14,17,20-heptahydroxy-3-(c-hydroxycarbonimidoylmethyl)-9-(3h-imidazol-4-ylmethyl)-15-(sec-butyl)-1,4,7,10,13,16,19-heptaazacyclopentacosa-1,4,7,10,13,16,19-heptaen-21-yl]-c-hydroxycarbonimidoyl}-2-methylbutyl]-c-hydroxycarbonimidoyl}butanoic acid

C66H103N17O16S (1421.7489)


   

4-{[2-({[2-(1-amino-2-methylbutyl)-4,5-dihydro-1,3-thiazol-4-yl](hydroxy)methylidene}amino)-1-hydroxy-4-methylpentylidene]amino}-4-[(1-{[18-(3-aminopropyl)-12-benzyl-6-(carboxymethyl)-2,5,8,11,14,17,20-heptahydroxy-3-(c-hydroxycarbonimidoylmethyl)-9-(3h-imidazol-4-ylmethyl)-15-(sec-butyl)-1,4,7,10,13,16,19-heptaazacyclopentacosa-1,4,7,10,13,16,19-heptaen-21-yl]-c-hydroxycarbonimidoyl}-2-methylbutyl)-c-hydroxycarbonimidoyl]butanoic acid

4-{[2-({[2-(1-amino-2-methylbutyl)-4,5-dihydro-1,3-thiazol-4-yl](hydroxy)methylidene}amino)-1-hydroxy-4-methylpentylidene]amino}-4-[(1-{[18-(3-aminopropyl)-12-benzyl-6-(carboxymethyl)-2,5,8,11,14,17,20-heptahydroxy-3-(c-hydroxycarbonimidoylmethyl)-9-(3h-imidazol-4-ylmethyl)-15-(sec-butyl)-1,4,7,10,13,16,19-heptaazacyclopentacosa-1,4,7,10,13,16,19-heptaen-21-yl]-c-hydroxycarbonimidoyl}-2-methylbutyl)-c-hydroxycarbonimidoyl]butanoic acid

C66H103N17O16S (1421.7489)