Exact Mass: 1367.2742224
Exact Mass Matches: 1367.2742224
Found 4 metabolites which its exact mass value is equals to given mass value 1367.2742224,
within given mass tolerance error 6.4E-8 dalton. Try search metabolite list with more accurate mass tolerance error
1.28E-8 dalton.
Calicheamicin
A calcheamicin in which contains 3-O-methyl-alpha-L-rhamnosyl, 2,6-dideoxy-4-thio-beta-D-ribo-hexopyranosyl, and 4-amino-4,6-dideoxy-2-O-[2,4-dideoxy-4-(ethylamino)-3-O-methyl-alpha-L-threo-pentopyranosyl]-alpha-L-idopyranose units and in which the aromatic ring contains an iodo substituent. D009676 - Noxae > D009153 - Mutagens D000970 - Antineoplastic Agents
Calicheamicin
Calicheamicin
Enediyne aminoglycosides derived from the bacterium MICROMONOSPORA ECHINOSPORA that are used as antineoplastic antibiotics. They bind to DNA in both healthy and tumor cells, resulting in strand scission and cell death. Calicheamicin is a naturally occurring organic compound that belongs to the class of macrocyclic lactones. It is renowned for its potent antitumor activity and was originally isolated from soil as an antibiotic. The compound's distinctive feature is its ability to bind to DNA and induce double-strand DNA breaks, which is a highly effective mechanism for inhibiting the proliferation of tumor cells. Due to its significant cytotoxicity, Calicheamicin and its derivatives have been the subject of research and development for antitumor drugs. However, the clinical application of Calicheamicin is limited by its strong toxicity. It is often used in combination with other treatments to reduce side effects and enhance its therapeutic efficacy. D000970 - Antineoplastic Agents > D000903 - Antibiotics, Antineoplastic > D000080084 - Calicheamicins