Exact Mass: 1043.3241
Exact Mass Matches: 1043.3241
Found 62 metabolites which its exact mass value is equals to given mass value 1043.3241,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
OPC8-CoA
OPC8-CoA participates in alpha-Linolenic acid metabolism. OPC8-CoA is produced from 8-[(1R,2R)-3-Oxo-2-{(Z)-pent-2-enyl}cyclopentyl]octanoate. However, OPC8-CoA reacts with acyl-CoA oxidase [EC:1.3.3.6] to give rise to trans-2-Enoyl-OPC8-CoA.
(10Z,13Z)-Nonadecadienoyl-CoA
A long-chain fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of (10Z,13Z)-nonadecadienoic acid.
(9E,11E,15Z)-9-hydroxyoctadeca-9,11,15-trienoyl-CoA
(9e,11e,15z)-9-hydroxyoctadeca-9,11,15-trienoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a (9E_11E_15Z)-9-hydroxyoctadeca-9_11_15-trienoic acid thioester of coenzyme A. (9e,11e,15z)-9-hydroxyoctadeca-9,11,15-trienoyl-coa is an acyl-CoA with 18 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. (9e,11e,15z)-9-hydroxyoctadeca-9,11,15-trienoyl-coa is therefore classified as a long chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. (9e,11e,15z)-9-hydroxyoctadeca-9,11,15-trienoyl-coa, being a long chain acyl-CoA is a substrate for long chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, (9E,11E,15Z)-9-hydroxyoctadeca-9,11,15-trienoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of (9E,11E,15Z)-9-hydroxyoctadeca-9,11,15-trienoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts (9E,11E,15Z)-9-hydroxyoctadeca-9,11,15-trienoyl-CoA into (9E_11E_15Z)-9-hydroxyoctadeca-9_11_15-trienoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, (9E_11E_15Z)-9-hydroxyoctadeca-9_11_15-trienoylcarnitine is converted back to (9E,11E,15Z)-9-hydroxyoctadeca-9,11,15-trienoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of (9E,11E,15Z)-9-hydroxyoctadeca-9,11,15-trienoyl-CoA occurs in four steps. First, since (9E,11E,15Z)-9-hydroxyoctadeca-9,11,15-trienoyl-CoA is a long chain acyl-CoA it is the substrate for a ...
(9Z,12Z,15Z)-17-hydroxyoctadeca-9,12,15-trienoyl-CoA
(9z,12z,15z)-17-hydroxyoctadeca-9,12,15-trienoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a (9Z_12Z_15Z)-17-hydroxyoctadeca-9_12_15-trienoic acid thioester of coenzyme A. (9z,12z,15z)-17-hydroxyoctadeca-9,12,15-trienoyl-coa is an acyl-CoA with 18 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. (9z,12z,15z)-17-hydroxyoctadeca-9,12,15-trienoyl-coa is therefore classified as a long chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. (9z,12z,15z)-17-hydroxyoctadeca-9,12,15-trienoyl-coa, being a long chain acyl-CoA is a substrate for long chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, (9Z,12Z,15Z)-17-hydroxyoctadeca-9,12,15-trienoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of (9Z,12Z,15Z)-17-hydroxyoctadeca-9,12,15-trienoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts (9Z,12Z,15Z)-17-hydroxyoctadeca-9,12,15-trienoyl-CoA into (9Z_12Z_15Z)-17-hydroxyoctadeca-9_12_15-trienoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, (9Z_12Z_15Z)-17-hydroxyoctadeca-9_12_15-trienoylcarnitine is converted back to (9Z,12Z,15Z)-17-hydroxyoctadeca-9,12,15-trienoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of (9Z,12Z,15Z)-17-hydroxyoctadeca-9,12,15-trienoyl-CoA occurs in four steps. First, since (9Z,12Z,15Z)-17-hydroxyoctadeca-9,12,15-trienoyl-CoA is a long chain acyl-CoA it is the sub...
(10E,13E)-Nonadeca-10,13-dienoyl-CoA
(10e,13e)-nonadeca-10,13-dienoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a (10E_13E)-nonadeca-10_13-dienoic acid thioester of coenzyme A. (10e,13e)-nonadeca-10,13-dienoyl-coa is an acyl-CoA with 1 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. (10e,13e)-nonadeca-10,13-dienoyl-coa is therefore classified as a short chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. (10e,13e)-nonadeca-10,13-dienoyl-coa, being a short chain acyl-CoA is a substrate for short chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, (10E,13E)-Nonadeca-10,13-dienoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of (10E,13E)-Nonadeca-10,13-dienoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts (10E,13E)-Nonadeca-10,13-dienoyl-CoA into (10E_13E)-Nonadeca-10_13-dienoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, (10E_13E)-Nonadeca-10_13-dienoylcarnitine is converted back to (10E,13E)-Nonadeca-10,13-dienoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of (10E,13E)-Nonadeca-10,13-dienoyl-CoA occurs in four steps. First, since (10E,13E)-Nonadeca-10,13-dienoyl-CoA is a short chain acyl-CoA it is the substrate for a short chain acyl-CoA dehydrogenase, which catalyzes dehydrogenation of (10E,13E)-Nonadeca-10,13-dienoyl-CoA, creating a double bond between the alpha and beta carbons. FAD is the hydrogen acce...
(5Z,9Z)-Nonadeca-5,9-dienoyl-CoA
(5z,9z)-nonadeca-5,9-dienoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a (5Z_9Z)-nonadeca-5_9-dienoic acid thioester of coenzyme A. (5z,9z)-nonadeca-5,9-dienoyl-coa is an acyl-CoA with 1 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. (5z,9z)-nonadeca-5,9-dienoyl-coa is therefore classified as a short chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. (5z,9z)-nonadeca-5,9-dienoyl-coa, being a short chain acyl-CoA is a substrate for short chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, (5Z,9Z)-Nonadeca-5,9-dienoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of (5Z,9Z)-Nonadeca-5,9-dienoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts (5Z,9Z)-Nonadeca-5,9-dienoyl-CoA into (5Z_9Z)-Nonadeca-5_9-dienoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, (5Z_9Z)-Nonadeca-5_9-dienoylcarnitine is converted back to (5Z,9Z)-Nonadeca-5,9-dienoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of (5Z,9Z)-Nonadeca-5,9-dienoyl-CoA occurs in four steps. First, since (5Z,9Z)-Nonadeca-5,9-dienoyl-CoA is a short chain acyl-CoA it is the substrate for a short chain acyl-CoA dehydrogenase, which catalyzes dehydrogenation of (5Z,9Z)-Nonadeca-5,9-dienoyl-CoA, creating a double bond between the alpha and beta carbons. FAD is the hydrogen acceptor, yielding FADH2. Second, Enoyl-CoA hydrase catalyze...
9-(3,4-dimethyl-5-propylfuran-2-yl)nonanoyl-CoA
9-(3,4-dimethyl-5-propylfuran-2-yl)nonanoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a 9-(3_4-dimethyl-5-propylfuran-2-yl)nonanoic acid thioester of coenzyme A. 9-(3,4-dimethyl-5-propylfuran-2-yl)nonanoyl-coa is an acyl-CoA with 16 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. 9-(3,4-dimethyl-5-propylfuran-2-yl)nonanoyl-coa is therefore classified as a long chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. 9-(3,4-dimethyl-5-propylfuran-2-yl)nonanoyl-coa, being a long chain acyl-CoA is a substrate for long chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, 9-(3,4-dimethyl-5-propylfuran-2-yl)nonanoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of 9-(3,4-dimethyl-5-propylfuran-2-yl)nonanoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts 9-(3,4-dimethyl-5-propylfuran-2-yl)nonanoyl-CoA into 9-(3_4-dimethyl-5-propylfuran-2-yl)nonanoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, 9-(3_4-dimethyl-5-propylfuran-2-yl)nonanoylcarnitine is converted back to 9-(3,4-dimethyl-5-propylfuran-2-yl)nonanoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of 9-(3,4-dimethyl-5-propylfuran-2-yl)nonanoyl-CoA occurs in four steps. First, since 9-(3,4-dimethyl-5-propylfuran-2-yl)nonanoyl-CoA is a long chain acyl-CoA it is the substrate for a long chain acyl-CoA dehydrogenase, which catalyzes d...
(6Z)-11-(3-pentyloxiran-2-yl)undeca-6,9-dienoyl-CoA
(6z)-11-(3-pentyloxiran-2-yl)undeca-6,9-dienoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a (6Z)-11-(3-pentyloxiran-2-yl)undeca-6_9-dienoic acid thioester of coenzyme A. (6z)-11-(3-pentyloxiran-2-yl)undeca-6,9-dienoyl-coa is an acyl-CoA with 18 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. (6z)-11-(3-pentyloxiran-2-yl)undeca-6,9-dienoyl-coa is therefore classified as a long chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. (6z)-11-(3-pentyloxiran-2-yl)undeca-6,9-dienoyl-coa, being a long chain acyl-CoA is a substrate for long chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, (6Z)-11-(3-pentyloxiran-2-yl)undeca-6,9-dienoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of (6Z)-11-(3-pentyloxiran-2-yl)undeca-6,9-dienoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts (6Z)-11-(3-pentyloxiran-2-yl)undeca-6,9-dienoyl-CoA into (6Z)-11-(3-pentyloxiran-2-yl)undeca-6_9-dienoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, (6Z)-11-(3-pentyloxiran-2-yl)undeca-6_9-dienoylcarnitine is converted back to (6Z)-11-(3-pentyloxiran-2-yl)undeca-6,9-dienoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of (6Z)-11-(3-pentyloxiran-2-yl)undeca-6,9-dienoyl-CoA occurs in four steps. First, since (6Z)-11-(3-pentyloxiran-2-yl)undeca-6,9-dienoyl-CoA is a long chain acyl-CoA it is the substrate for a ...
7-(5-heptylfuran-2-yl)heptanoyl-CoA
7-(5-heptylfuran-2-yl)heptanoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a 7-(5-heptylfuran-2-yl)heptanoic acid thioester of coenzyme A. 7-(5-heptylfuran-2-yl)heptanoyl-coa is an acyl-CoA with 18 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. 7-(5-heptylfuran-2-yl)heptanoyl-coa is therefore classified as a long chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. 7-(5-heptylfuran-2-yl)heptanoyl-coa, being a long chain acyl-CoA is a substrate for long chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, 7-(5-heptylfuran-2-yl)heptanoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of 7-(5-heptylfuran-2-yl)heptanoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts 7-(5-heptylfuran-2-yl)heptanoyl-CoA into 7-(5-heptylfuran-2-yl)heptanoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, 7-(5-heptylfuran-2-yl)heptanoylcarnitine is converted back to 7-(5-heptylfuran-2-yl)heptanoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of 7-(5-heptylfuran-2-yl)heptanoyl-CoA occurs in four steps. First, since 7-(5-heptylfuran-2-yl)heptanoyl-CoA is a long chain acyl-CoA it is the substrate for a long chain acyl-CoA dehydrogenase, which catalyzes dehydrogenation of 7-(5-heptylfuran-2-yl)heptanoyl-CoA, creating a double bond between the alpha and beta carbons. FAD is the hydrogen acceptor, yielding FAD...
8-(5-hexylfuran-2-yl)octanoyl-CoA
8-(5-hexylfuran-2-yl)octanoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is an 8-(5-hexylfuran-2-yl)octanoic acid thioester of coenzyme A. 8-(5-hexylfuran-2-yl)octanoyl-coa is an acyl-CoA with 18 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. 8-(5-hexylfuran-2-yl)octanoyl-coa is therefore classified as a long chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. 8-(5-hexylfuran-2-yl)octanoyl-coa, being a long chain acyl-CoA is a substrate for long chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, 8-(5-hexylfuran-2-yl)octanoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of 8-(5-hexylfuran-2-yl)octanoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts 8-(5-hexylfuran-2-yl)octanoyl-CoA into 8-(5-hexylfuran-2-yl)octanoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, 8-(5-hexylfuran-2-yl)octanoylcarnitine is converted back to 8-(5-hexylfuran-2-yl)octanoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of 8-(5-hexylfuran-2-yl)octanoyl-CoA occurs in four steps. First, since 8-(5-hexylfuran-2-yl)octanoyl-CoA is a long chain acyl-CoA it is the substrate for a long chain acyl-CoA dehydrogenase, which catalyzes dehydrogenation of 8-(5-hexylfuran-2-yl)octanoyl-CoA, creating a double bond between the alpha and beta carbons. FAD is the hydrogen acceptor, yielding FADH2. Second, Enoyl-CoA hydra...
9-(5-pentylfuran-2-yl)nonanoyl-CoA
9-(5-pentylfuran-2-yl)nonanoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a 9-(5-pentylfuran-2-yl)nonanoic acid thioester of coenzyme A. 9-(5-pentylfuran-2-yl)nonanoyl-coa is an acyl-CoA with 18 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. 9-(5-pentylfuran-2-yl)nonanoyl-coa is therefore classified as a long chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. 9-(5-pentylfuran-2-yl)nonanoyl-coa, being a long chain acyl-CoA is a substrate for long chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, 9-(5-pentylfuran-2-yl)nonanoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of 9-(5-pentylfuran-2-yl)nonanoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts 9-(5-pentylfuran-2-yl)nonanoyl-CoA into 9-(5-pentylfuran-2-yl)nonanoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, 9-(5-pentylfuran-2-yl)nonanoylcarnitine is converted back to 9-(5-pentylfuran-2-yl)nonanoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of 9-(5-pentylfuran-2-yl)nonanoyl-CoA occurs in four steps. First, since 9-(5-pentylfuran-2-yl)nonanoyl-CoA is a long chain acyl-CoA it is the substrate for a long chain acyl-CoA dehydrogenase, which catalyzes dehydrogenation of 9-(5-pentylfuran-2-yl)nonanoyl-CoA, creating a double bond between the alpha and beta carbons. FAD is the hydrogen acceptor, yielding FADH2. Second, En...
9-(5-butyl-3-methylfuran-2-yl)nonanoyl-CoA
9-(5-butyl-3-methylfuran-2-yl)nonanoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a 9-(5-butyl-3-methylfuran-2-yl)nonanoic acid thioester of coenzyme A. 9-(5-butyl-3-methylfuran-2-yl)nonanoyl-coa is an acyl-CoA with 17 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. 9-(5-butyl-3-methylfuran-2-yl)nonanoyl-coa is therefore classified as a long chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. 9-(5-butyl-3-methylfuran-2-yl)nonanoyl-coa, being a long chain acyl-CoA is a substrate for long chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, 9-(5-butyl-3-methylfuran-2-yl)nonanoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of 9-(5-butyl-3-methylfuran-2-yl)nonanoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts 9-(5-butyl-3-methylfuran-2-yl)nonanoyl-CoA into 9-(5-butyl-3-methylfuran-2-yl)nonanoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, 9-(5-butyl-3-methylfuran-2-yl)nonanoylcarnitine is converted back to 9-(5-butyl-3-methylfuran-2-yl)nonanoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of 9-(5-butyl-3-methylfuran-2-yl)nonanoyl-CoA occurs in four steps. First, since 9-(5-butyl-3-methylfuran-2-yl)nonanoyl-CoA is a long chain acyl-CoA it is the substrate for a long chain acyl-CoA dehydrogenase, which catalyzes dehydrogenation of 9-(5-butyl-3-methylfuran-2-yl)nonanoyl-CoA, cre...
8-{3-[(2Z,5Z)-octa-2,5-dien-1-yl]oxiran-2-yl}octanoyl-CoA
8-{3-[(2z,5z)-octa-2,5-dien-1-yl]oxiran-2-yl}octanoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is an 8-{3-[(2Z_5Z)-octa-2_5-dien-1-yl]oxiran-2-yl}octanoic acid thioester of coenzyme A. 8-{3-[(2z,5z)-octa-2,5-dien-1-yl]oxiran-2-yl}octanoyl-coa is an acyl-CoA with 18 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. 8-{3-[(2z,5z)-octa-2,5-dien-1-yl]oxiran-2-yl}octanoyl-coa is therefore classified as a long chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. 8-{3-[(2z,5z)-octa-2,5-dien-1-yl]oxiran-2-yl}octanoyl-coa, being a long chain acyl-CoA is a substrate for long chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, 8-{3-[(2Z,5Z)-octa-2,5-dien-1-yl]oxiran-2-yl}octanoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of 8-{3-[(2Z,5Z)-octa-2,5-dien-1-yl]oxiran-2-yl}octanoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts 8-{3-[(2Z,5Z)-octa-2,5-dien-1-yl]oxiran-2-yl}octanoyl-CoA into 8-{3-[(2Z_5Z)-octa-2_5-dien-1-yl]oxiran-2-yl}octanoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, 8-{3-[(2Z_5Z)-octa-2_5-dien-1-yl]oxiran-2-yl}octanoylcarnitine is converted back to 8-{3-[(2Z,5Z)-octa-2,5-dien-1-yl]oxiran-2-yl}octanoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of 8-{3-[(2Z,5Z)-octa-2,5-dien-1-yl]oxiran-2-yl}octanoyl-CoA occurs in four steps. First, since 8-{3-[(2Z,5Z)-octa-2,5-dien-1-...
7-(3,4-dimethyl-5-pentylfuran-2-yl)heptanoyl-CoA
7-(3,4-dimethyl-5-pentylfuran-2-yl)heptanoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a 7-(3_4-dimethyl-5-pentylfuran-2-yl)heptanoic acid thioester of coenzyme A. 7-(3,4-dimethyl-5-pentylfuran-2-yl)heptanoyl-coa is an acyl-CoA with 16 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. 7-(3,4-dimethyl-5-pentylfuran-2-yl)heptanoyl-coa is therefore classified as a long chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. 7-(3,4-dimethyl-5-pentylfuran-2-yl)heptanoyl-coa, being a long chain acyl-CoA is a substrate for long chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, 7-(3,4-dimethyl-5-pentylfuran-2-yl)heptanoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of 7-(3,4-dimethyl-5-pentylfuran-2-yl)heptanoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts 7-(3,4-dimethyl-5-pentylfuran-2-yl)heptanoyl-CoA into 7-(3_4-dimethyl-5-pentylfuran-2-yl)heptanoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, 7-(3_4-dimethyl-5-pentylfuran-2-yl)heptanoylcarnitine is converted back to 7-(3,4-dimethyl-5-pentylfuran-2-yl)heptanoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of 7-(3,4-dimethyl-5-pentylfuran-2-yl)heptanoyl-CoA occurs in four steps. First, since 7-(3,4-dimethyl-5-pentylfuran-2-yl)heptanoyl-CoA is a long chain acyl-CoA it is the substrate for a long chain acyl-CoA dehydrogenase, whic...
CoA 18:3;O
palmitoyl-CoA
Palmitoyl-CoA, also known as hexadecanoyl CoA, is a coenzyme A derivative of palmitic acid, one of the most common saturated fatty acids found in animals and plants (YMDB: YMDB00527). Palmitoyl-CoA belongs to the class of organic compounds known as 2,3,4-saturated fatty acyl coas. These are acyl-CoAs carrying a 2,3,4-saturated fatty acyl chain. Palmitoyl-CoA is part of the carnitine shuttle system, which transports other fatty acyl-CoA molecules into the mitochondria for β-oxidation . Palmitoyl-CoA can be found in many food items, some of which are apple, apricot, asparagus and avocado, which makes palmitoyl-CoA a potential biomarker for the consumption of these food products.
S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] 8-[(1S,2S)-3-oxo-2-[(Z)-pent-2-enyl]cyclopentyl]octanethioate
(6Z)-11-(3-pentyloxiran-2-yl)undeca-6,9-dienoyl-CoA
(9E,11E,15Z)-9-hydroxyoctadeca-9,11,15-trienoyl-CoA
(9Z,12Z,15Z)-17-hydroxyoctadeca-9,12,15-trienoyl-CoA
8-{3-[(2Z,5Z)-octa-2,5-dien-1-yl]oxiran-2-yl}octanoyl-CoA
1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate)(7-)
S-[2-[3-[[(2R)-4-[[[(2R,3R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] 8-[(1S,2S)-3-oxo-2-[(Z)-pent-2-enyl]cyclopentyl]octanethioate
3-oxooctadecanoyl-CoA(4-)
A 3-oxo-fatty acyl-CoA(4-) arising from deprotonation of the phosphate and diphosphate groups of 3-oxooctadecanoyl-CoA; major species at pH 7.3.
pristanoyl-CoA(4-)
A multi-methyl-branched fatty acyl-CoA(4-) oxanion arising from deprotonation of the phosphate and diphosphate OH groups of pristanoyl-CoA; major species at pH 7.3.
(3S)-3-hydroxyoleoyl-CoA(4-)
A 3-hydroxyacyl-CoA(4-) obtained by deprotonation of the phosphate and diphosphate OH groups of (3S)-3-hydroxyoleoyl-CoA; major species at pH 7.3.
(9Z,12Z)-3-oxolinoleoyl-CoA
A 3-oxo-fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of (9Z,12Z)-3-oxolinoleic acid.
(2S)-pristanoyl-CoA(4-)
A multi-methyl-branched fatty acyl-CoA(4-) obtained by deprotonation of phosphate and diphosphate functions of (2S)-pristanoyl-CoA; major species at pH 7.3.
12-methyloctadecanoyl-CoA(4-)
A long-chain fatty acyl-CoA(4-) oxanion arising from deprotonation of the phosphate and diphosphate OH groups of 12-methyloctadecanoyl-CoA; major species at pH 7.3
(2R)-pristanoyl-CoA(4-)
A multi-methyl-branched fatty acyl-CoA(4-) obtained by deprotonation of phosphate and diphosphate functions of (2R)-pristanoyl-CoA; major species at pH 7.3
1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate)(7-)
A 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate(7-) in which the phosphatidyl acyl groups at positions 1 and 2 are both specified as hexadecanoyl (palmitoyl).
nonadecanoyl-CoA(4-)
An acyl-CoA(4-) arising from deprotonation of the phosphate and diphosphate functions of nonadecanoyl-CoA.
(3R,11Z)-3-hydroxyoctadecenoyl-CoA(4-)
An (R)-3-hydroxyacyl-CoA(4-) obtained by deprotonation of the phosphate and diphosphate OH groups of (3R,11Z)-3-hydroxyoctadecenoyl-CoA; major species at pH 7.3.
18-hydroxyoleoyl-CoA(4-)
A monounsaturated fatty acyl-CoA(4-) obtained by deprotonation of the phosphate and diphosphate OH groups of 18-hydroxyoleoyl-CoA; major species at pH 7.3.
3-oxoisooctadecanoyl-CoA(4-)
A 3-oxo-fatty acyl-CoA(4-) arising from deprotonation of the phosphate and diphosphate functions of 3-oxoisooctadecanoyl-CoA.
(11Z)-18-hydroxyoctadecenoyl-CoA(4-)
A monounsaturated fatty acyl-CoA(4-) obtained by deprotonation of the phosphate and diphosphate OH groups of (11Z)-18-hydroxyoctadecenoyl-CoA; major species at pH 7.3.
