Exact Mass: 1002.430248

Exact Mass Matches: 1002.430248

Found 1 metabolites which its exact mass value is equals to given mass value 1002.430248, within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error 4.0E-5 dalton.

Sacubitril/Valsartan

Sacubitril/Valsartan

C48H55N6Na3O8.2.5H2O (1002.430248)


Sacubitril/Valsartan (LCZ696), comprised Valsartan and Sacubitril (AHU377) in 1:1 molar ratio, is a first-in-class, orally bioavailable, and dual-acting angiotensin receptor-neprilysin (ARN) inhibitor for hypertension and heart failure[1][2][3]. Sacubitril/Valsartan ameliorates diabetic cardiomyopathy by inhibiting inflammation, oxidative stress and apoptosis[4].