Exact Mass: 1002.430248

Exact Mass Matches: 1002.430248

Found 1 metabolites which its exact mass value is equals to given mass value 1002.430248, within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error 8.0E-6 dalton.

Sacubitril/Valsartan

Sacubitril/Valsartan

C48H55N6Na3O8.2.5H2O (1002.430248)


Sacubitril/Valsartan (LCZ696), comprised Valsartan and Sacubitril (AHU377) in 1:1 molar ratio, is a first-in-class, orally bioavailable, and dual-acting angiotensin receptor-neprilysin (ARN) inhibitor for hypertension and heart failure[1][2][3]. Sacubitril/Valsartan ameliorates diabetic cardiomyopathy by inhibiting inflammation, oxidative stress and apoptosis[4].