Classification Term: 917
Isoquinolines and derivatives (ontology term: CHEMONTID:0002566)
Aromatic polycyclic compounds containing an isoquinoline moiety, which consists of a benzene ring fused to a pyridine ring and forming benzo[c]pyridine." []
found 14 associated metabolites at class metabolite taxonomy ontology rank level.
Ancestor: Organoheterocyclic compounds
Child Taxonomies: Benzylisoquinolines, Isoquinolones and derivatives, Naphthylisoquinolines, Isoquinoline quinones, 1,3-isoquinolinediones, 1,4-isoquinolinediones, 1-phenethylisoquinolines
Isoquinoline
Isoquinoline is a flavouring agent Being an analog of pyridine, isoquinoline is a weak base, with a pKb of 8.6. It protonates to form salts upon treatment with strong acids, such as HCl. It forms adducts with Lewis acids, such as BF3. Isoquinoline is a colorless hygroscopic liquid at room temperature with a penetrating, unpleasant odor. Impure samples can appear brownish, as is typical for nitrogen heterocycles. It crystallizes platelets that have a low solubility in water but dissolve well in ethanol, acetone, diethyl ether, carbon disulfide, and other common organic solvents. It is also soluble in dilute acids as the protonated derivative. Isoquinoline is a heterocyclic aromatic organic compound. It is a structural isomer of quinoline. Isoquinoline and quinoline are benzopyridines, which are composed of a benzene ring fused to a pyridine ring. In a broader sense, the term isoquinoline is used to make reference to isoquinoline derivatives. 1-Benzylisoquinoline is the structural backbone in naturally occurring alkaloids including papaverine and morphine. The isoquinoline ring in these natural compound derives from the aromatic amino acid tyrosine Flavouring agent KEIO_ID I067
Isosalsolidine
C12H13NO2 (203.09462380000002)
Isosalsolidine is found in herbs and spices. Isosalsolidine is a trace constituent in seeds of Nigella sativa (black cumin). Trace constituent in seeds of Nigella sativa (black cumin). Isosalsolidine is found in herbs and spices.
1-(5-Isoquinolinesulfonyl)-2-methylpiperazine
D004791 - Enzyme Inhibitors
1,5-Isoquinolinediol
D000970 - Antineoplastic Agents > D000067856 - Poly(ADP-ribose) Polymerase Inhibitors D004791 - Enzyme Inhibitors
N-(2-(Methylamino)ethyl)-5-isoquinolinesulfonamide
D004791 - Enzyme Inhibitors > D047428 - Protein Kinase Inhibitors
N-(2-Hydroxyethyl)-2-(1-isoquinolinylmethylene)hydrazinecarbothioamide
Binfloxacin
C19H22FN3O3 (359.16451140000004)
C254 - Anti-Infective Agent > C258 - Antibiotic > C795 - Quinolone Antibiotic
Cortistatin A
Fasudil
C - Cardiovascular system > C04 - Peripheral vasodilators > C04A - Peripheral vasodilators D002317 - Cardiovascular Agents > D002121 - Calcium Channel Blockers D004791 - Enzyme Inhibitors > D047428 - Protein Kinase Inhibitors D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor D000077264 - Calcium-Regulating Hormones and Agents D049990 - Membrane Transport Modulators
N-(2-Guanidinoethyl)-5-isoquinolinesulfonamide
D002317 - Cardiovascular Agents > D002121 - Calcium Channel Blockers D004791 - Enzyme Inhibitors > D047428 - Protein Kinase Inhibitors D000077264 - Calcium-Regulating Hormones and Agents D049990 - Membrane Transport Modulators
Ripasudil
C15H18FN3O2S (323.11037000000005)