Classification Term: 609

4-quinolinemethanols (ontology term: CHEMONTID:0004538)

Organoheterocyclic compounds containing a quinoline moiety substituted at the 4-position with a methanol." []

found 2 associated metabolites at sub_class metabolite taxonomy ontology rank level.

Ancestor: Quinolines and derivatives

Child Taxonomies: There is no child term of current ontology term.

Mefloquine

alpha-2-Piperidinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol

C17H16F6N2O (378.1167)


Mefloquine is only found in individuals that have used or taken this drug. It is a phospholipid-interacting antimalarial drug (antimalarials). It is very effective against plasmodium falciparum with very few side effects. [PubChem]Mefloquine has been found to produce swelling of the Plasmodium falciparum food vacuoles. It may act by forming toxic complexes with free heme that damage membranes and interact with other plasmodial components. P - Antiparasitic products, insecticides and repellents > P01 - Antiprotozoals > P01B - Antimalarials > P01BC - Methanolquinolines D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C277 - Antiprotozoal Agent COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials COVID info from clinicaltrials, clinicaltrial Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS

   

Quinacainol

1-(2-tert-butylquinolin-4-yl)-3-(piperidin-4-yl)propan-1-ol

C21H30N2O (326.2358)


C78274 - Agent Affecting Cardiovascular System > C47793 - Antiarrhythmic Agent