Classification Term: 52

Aminopyridines and derivatives (ontology term: CHEMONTID:0000283)

Organic heterocyclic compounds containing an amino group attached to a pyridine ring." []

found 13 associated metabolites at sub_class metabolite taxonomy ontology rank level.

Ancestor: Pyridines and derivatives

Child Taxonomies: There is no child term of current ontology term.

Phenazopyridine

3-[(E)-2-phenyldiazen-1-yl]pyridine-2,6-diamine

C11H11N5 (213.1014406)


Phenazopyridine is only found in individuals that have used or taken this drug. It is a local anesthetic that has been used in urinary tract disorders. Its use is limited by problems with toxicity (primarily blood disorders) and potential carcinogenicity. [PubChem]Phenazopyridines mechanism of action is not well known, and only basic information on its interaction with the body is available. It is known that the chemical has a direct topical analgesic effect on the mucosa lining of the urinary tract. C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic G - Genito urinary system and sex hormones > G04 - Urologicals > G04B - Urologicals KEIO_ID P036; [MS2] KO009187 KEIO_ID P036

   

3-Hydroxy-4-aminopyridine

4-imino-1,4-dihydropyridin-3-ol

C5H6N2O (110.0480106)


3-Hydroxy-4-aminopyridine is a metabolite of dalfampridine. 4-Aminopyridine (fampridine, USAN dalfampridine) is an organic compound with the chemical formula C5H4N–NH2. The molecule is one of the three isomeric amines of pyridine. It is used primarily as a research tool, in characterizing subtypes of potassium channel, and has also been used to manage some of the symptoms of multiple sclerosis, and is indicated for symptomatic improvement of walking in adults with several variations of the disease. (Wikipedia) 3-Hydroxy-4-aminopyridine is an endogenous metabolite.

   

2-((3-Aminopyridin-2-yl)methylene)hydrazinecarbothioamide

N-{[(3-aminopyridin-2-yl)methylidene]amino}carbamimidothioate

C7H9N5S (195.0578634)


   

N4-Cyclopropylpyridine-3,4-diamine

N4-Cyclopropylpyridine-3,4-diamine

C8H11N3 (149.0952926)


   

2-Amino-4-chloropyridine

2-Amino-4-chloropyridine

C5H5ClN2 (128.014124)


   

2-Amino-5-chloropyridine

2-Amino-5-chloropyridine

C5H5ClN2 (128.014124)


   

2-Aminopyridine

alpha-Aminopyridine, hydrochloride

C5H6N2 (94.05309559999999)


   

2,2'-Dipyridylamine

N-(pyridin-2-yl)pyridin-2-amine

C10H9N3 (171.07964339999998)


   

3,4-Diaminopyridine

4-imino-1,4-dihydropyridin-3-amine

C5H7N3 (109.0639942)


D018373 - Peripheral Nervous System Agents > D009465 - Neuromuscular Agents D002317 - Cardiovascular Agents > D026902 - Potassium Channel Blockers D049990 - Membrane Transport Modulators C93038 - Cation Channel Blocker N - Nervous system

   

2-Amino-4-methylpyridine

4-methyl-1,2-dihydropyridin-2-imine

C6H8N2 (108.06874479999999)


   

Carbamic acid, (5-amino-1,2-dihydro-3-(4-methylphenyl)pyrido(3,4-b)pyrazin-7-yl)-, ethyl ester

Carbamic acid, (5-amino-1,2-dihydro-3-(4-methylphenyl)pyrido(3,4-b)pyrazin-7-yl)-, ethyl ester

C17H19N5O2 (325.15386739999997)


D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D000777 - Anesthetics D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D020011 - Protective Agents > D002316 - Cardiotonic Agents D000970 - Antineoplastic Agents D002317 - Cardiovascular Agents

   

Dmap-ethyl-paf

4-(dimethylamino)-1-[2-({[2-ethoxy-3-(hexadecyloxy)propoxy](oxido)phosphanyl}oxy)ethyl]-3-oxo-3,4-dihydropyridin-1-ium

C30H57N2O6P (572.3954031999999)


   

Fenyramidol

2-(beta-Hydroxyphenethylamino)pyridine hydrochloride

C13H14N2O (214.1106074)


M - Musculo-skeletal system > M03 - Muscle relaxants > M03B - Muscle relaxants, centrally acting agents C78281 - Agent Affecting Musculoskeletal System > C29696 - Muscle Relaxant