Classification Term: 424

Imidazopyridines (ontology term: CHEMONTID:0000328)

Organic polycyclic compounds containing an imidazole ring fused to a pyridine ring. Imidazole is 5-membered ring consisting of three carbon atoms, and two nitrogen centers at the 1- and 3-positions. Pyridine is a 6-membered ring consisting of five carbon atoms and one nitrogen center." []

found 19 associated metabolites at class metabolite taxonomy ontology rank level.

Ancestor: Organoheterocyclic compounds

Child Taxonomies: Imidazopyridinones , Imidazo-[4,5-c]pyridines

2-Amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole

10-methyl-1,3,8-triazatricyclo[7.4.0.0²,⁷]trideca-2(7),5,8,10,12-pentaen-4-imine

C11H10N4 (198.090542)

2-Amino-6-methyldipyrido[1,2-a:3,2-d]imidazole is a powerful mutagen presumed present in cooked food D009676 - Noxae > D009153 - Mutagens

2-Aminodipyrido[1,2-a:3',2'-d]imidazole

1,3,8-triazatricyclo[7.4.0.0²,⁷]trideca-2(7),3,5,8,10,12-hexaen-4-amine

C10H8N4 (184.0748928)

Parent compound of a group of potent mutagens found in cooked food D009676 - Noxae > D002273 - Carcinogens D009676 - Noxae > D009153 - Mutagens

2-Amino-1,6-dimethylfuro[3,2-e]imidazo[4,5-b]pyridine

6,11-dimethyl-10-oxa-2,4,6-triazatricyclo[7.3.0.0³,⁷]dodeca-1,3(7),4,8,11-pentaen-5-amine

C10H10N4O (202.085457)

2-Amino-1,6-dimethylfuro[3,2-e]imidazo[4,5-b]pyridine is found in animal foods. 2-Amino-1,6-dimethylfuro[3,2-e]imidazo[4,5-b]pyridine is isolated from cooked meat Isolated from cooked meats. 2-Amino-1,6-dimethylfuro[3,2-e]imidazo[4,5-b]pyridine is found in animal foods.

4-Azabenzimidazole

3H-Imidazo[4,5-b]pyridine

C6H5N3 (119.04834500000001)

5-Chloro-3-[2-(2,6-difluorophenyl)ethyl]-1H-imidazo[4,5-b]pyridine-2-thione

5-chloro-3-[2-(2,6-difluorophenyl)ethyl]-1H,2H,3H-imidazo[4,5-b]pyridine-2-thione

C14H10ClF2N3S (325.0251994)

4-(7-(((1R)-1-((3-Chloro-2-thienyl)methyl)propyl)amino)-3H-imidazo(4,5-b)pyridin-3-yl)-N-ethyl-2,3-dihydroxycyclopentanecarboxamide, (1S,2R,3S,4R)-

C22H28ClN5O3S (477.16012880000005)

3-Hydroxyamino-4,6-dimethyldipyrido(1,2-a:3',2'-d)imidazole

6,10-dimethyl-5-nitroso-1,3,8-triazatricyclo[7.4.0.0^{2,7}]trideca-2(7),5,8,10,12-pentaene

C12H12N4O (228.10110619999998)

D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents D004791 - Enzyme Inhibitors

Fadrozole

4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonitrile

C14H13N3 (223.1109418)

N-{4-[(3,5-Difluorophenyl)sulfonyl]benzyl}imidazo[1,2-A]pyridine-6-Carboxamide

N-{[4-(3,5-difluorobenzenesulphonyl)phenyl]methyl}imidazo[1,2-a]pyridine-6-carboximidic acid

C21H15F2N3O3S (427.08021440000005)

Imidazo[1,2-a]pyridine

Imidazo(1,2-a)pyridine

C7H6N2 (118.05309559999999)

Imigliptin

2-{[7-(3-aminopiperidin-1-yl)-3,5-dimethyl-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-1-yl]methyl}benzonitrile

C21H24N6O (376.20114939999996)

Linaprazan

8-{[(2,6-dimethylphenyl)methyl]amino}-N-(2-hydroxyethyl)-2,3-dimethylimidazo[1,2-a]pyridine-6-carboxamide

C21H26N4O2 (366.2055656)

C78276 - Agent Affecting Digestive System or Metabolism > C29701 - Anti-ulcer Agent > C29723 - Proton Pump Inhibitor

Minodronic acid

(1-Hydroxy-2-(imidazo(1,2-a)-pyridin-3-yl)ethylidene)bisphosphonic acid monohydrate

C9H12N2O7P2 (322.0119742)

C78281 - Agent Affecting Musculoskeletal System > C67439 - Bone Resorption Inhibitor D050071 - Bone Density Conservation Agents > D004164 - Diphosphonates Minodronic acid (YM-529) is a third-generation bisphosphonate that directly and indirectly prevents proliferation, induces apoptosis, and inhibits metastasis of various types of cancer cells. Minodronic acid (YM-529) is an antagonist of purinergic P2X2/3 receptors involved in pain[1][2].

Noberastine

N-{3-[(5-methylfuran-2-yl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}piperidin-4-amine

C17H21N5O (311.1746016)

C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist

N - Nervous system > N02 - Analgesics > N02C - Antimigraine preparations > N02CD - Calcitonin gene-related peptide (cgrp) antagonists C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent