Classification Term: 3505

Cyclohexylphenols (ontology term: CHEMONTID:0002099)

Compounds containing a cyclohexane lined to a phenol group." []

found 7 associated metabolites at sub_class metabolite taxonomy ontology rank level.

Ancestor: Benzene and substituted derivatives

Child Taxonomies: There is no child term of current ontology term.

O-Desmethyltramadol

3-[(1R,2R)-2-[(dimethylamino)methyl]-1-hydroxycyclohexyl]phenol

C15H23NO2 (249.1728698)


O-Desmethyltramadol is a metabolite of tramadol. O-Desmethyltramadol (O-DSMT) is an opioid analgesic and the main active metabolite of tramadol. (+)-O-Desmethyltramadol is the most important metabolite of tramadol produced in the liver after tramadol is consumed. This metabolite is considerably more potent as a μ-opioid agonist than the parent compound (Wikipedia). D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D009294 - Narcotics D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent D002491 - Central Nervous System Agents > D000700 - Analgesics

   

N,N,O-Tridesmethyltramadol

3-[(1R,2R)-2-(aminomethyl)-1-hydroxycyclohexyl]phenol

C13H19NO2 (221.1415714)


N,N,O-Tridesmethyltramadol is a metabolite of tramadol. Tramadol hydrochloride (trademarked as Conzip, Ryzolt, Ultracet, Ultram in the USA; Ralivia and Zytram XL in Canada) is a centrally-acting synthetic analgesic used to treat moderate to moderately-severe pain. The drug has a wide range of applications, including treatment of rheumatoid arthritis, restless legs syndrome, and fibromyalgia. It was launched and marketed as Tramal by the German pharmaceutical company Grnenthal GmbH in 1977 (Wikipedia).

   

N,O-Didesmethyltramadol

3-[(1R,2R)-1-hydroxy-2-[(methylamino)methyl]cyclohexyl]phenol

C14H21NO2 (235.15722060000002)


N,O-Didesmethyltramadol is a metabolite of tramadol. Tramadol hydrochloride (trademarked as Conzip, Ryzolt, Ultracet, Ultram in the USA; Ralivia and Zytram XL in Canada) is a centrally-acting synthetic analgesic used to treat moderate to moderately-severe pain. The drug has a wide range of applications, including treatment of rheumatoid arthritis, restless legs syndrome, and fibromyalgia. It was launched and marketed as Tramal by the German pharmaceutical company Grnenthal GmbH in 1977 (Wikipedia).

   

5-(1,1-Dimethylheptyl)-2-[5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol

3-(2-Hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol

C24H40O3 (376.297729)


D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D007155 - Immunologic Factors > D007166 - Immunosuppressive Agents D002491 - Central Nervous System Agents > D000700 - Analgesics

   

Adarotene

3-[3-(adamantan-1-yl)-4-hydroxy-[1,1-biphenyl]-4-yl]prop-2-enoic acid

C25H26O3 (374.1881846)


   

2-[(1r,3s)-3-Hydroxycyclohexyl]-5-(2-methyloctan-2-yl)phenol

cis-3-(2-Hydroxy-4-(1,1-dimethylheptylphenyl)-cyclohexan-1-ol)

C21H34O2 (318.2558664)


   

O-Demethyltramadol

3-{2-[(dimethylamino)methyl]-1-hydroxycyclohexyl}phenol

C15H23NO2 (249.1728698)


D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D009294 - Narcotics D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics