Classification Term: 3315

Fluorobenzenes (ontology term: CHEMONTID:0001100)

Compounds containing one or more fluorine atoms attached to a benzene ring." []

found 23 associated metabolites at category metabolite taxonomy ontology rank level.

Ancestor: Halobenzenes

Child Taxonomies: There is no child term of current ontology term.

Flusilazole

bis(4-fluorophenyl)-methyl-(1,2,4-triazol-1-ylmethyl)silane

C16H15F2N3Si (315.1003254)


Flusilazole is an organosilicon compound that is dimethylsilane in which the hydrogens attached to the silicon are replaced by p-fluorophenyl groups and a hydrogen attached to one of the methyl groups is replaced by a 1H-1,2,4-triazol-1-yl group. It is a broad-sepctrum fungicide used to protect a variety of crops. It has a role as a xenobiotic, an environmental contaminant, an EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor and an antifungal agrochemical. It is a member of monofluorobenzenes, a member of triazoles, an organosilicon compound, a conazole fungicide and a triazole fungicide. CONFIDENCE standard compound; INTERNAL_ID 555; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9550; ORIGINAL_PRECURSOR_SCAN_NO 9549 CONFIDENCE standard compound; INTERNAL_ID 555; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9630; ORIGINAL_PRECURSOR_SCAN_NO 9627 CONFIDENCE standard compound; INTERNAL_ID 555; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9444; ORIGINAL_PRECURSOR_SCAN_NO 9441 CONFIDENCE standard compound; INTERNAL_ID 555; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9499; ORIGINAL_PRECURSOR_SCAN_NO 9497 CONFIDENCE standard compound; INTERNAL_ID 555; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9537; ORIGINAL_PRECURSOR_SCAN_NO 9535 Highly potent broad-spectrum fungicide. Controls broad spectrum of diseases on economically important crops. Flusilazole is found in cereals and cereal products. Flusilazole is found in cereals and cereal products. Highly potent broad-spectrum fungicide. Controls broad spectrum of diseases on economically important crops. CONFIDENCE standard compound; INTERNAL_ID 4011 CONFIDENCE standard compound; INTERNAL_ID 2564 CONFIDENCE standard compound; INTERNAL_ID 8385 D016573 - Agrochemicals D010575 - Pesticides

   

Fluconazole

2,4-Difluoro-alpha,alpha-bis(1H-1,2,4-triazol-1-ylmethyl)benzyl alcohol

C13H12F2N6O (306.10406059999997)


Fluconazole is only found in individuals that have used or taken this drug. It is a triazole antifungal agent that is used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS. [PubChem]Fluconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. As ergosterol is an essential component of the fungal cell membrane, inhibition of its synthesis results in increased cellular permeability causing leakage of cellular contents. Fluconazole may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms, inhibit purine uptake, and impair triglyceride and/or phospholipid biosynthesis. J - Antiinfectives for systemic use > J02 - Antimycotics for systemic use > J02A - Antimycotics for systemic use > J02AC - Triazole and tetrazole derivatives D - Dermatologicals > D01 - Antifungals for dermatological use > D01A - Antifungals for topical use > D01AC - Imidazole and triazole derivatives D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D065088 - Steroid Synthesis Inhibitors D004791 - Enzyme Inhibitors > D065607 - Cytochrome P-450 Enzyme Inhibitors > D065689 - Cytochrome P-450 CYP2C19 Inhibitors D004791 - Enzyme Inhibitors > D065607 - Cytochrome P-450 Enzyme Inhibitors > D065688 - Cytochrome P-450 CYP2C9 Inhibitors D004791 - Enzyme Inhibitors > D065088 - Steroid Synthesis Inhibitors > D058888 - 14-alpha Demethylase Inhibitors COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials D000890 - Anti-Infective Agents > D000935 - Antifungal Agents C254 - Anti-Infective Agent > C514 - Antifungal Agent Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS

   

Fluorobenzene

Phenyl fluoride

C6H5F (96.0375262)


   

R-138727

2-{1-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4-sulphanyl-1,2,5,6-tetrahydropyridin-3-yl}acetic acid

C18H20FNO3S (349.1147862)


R-138727 is only found in individuals that have used or taken Prasugrel. R-138727 is a metabolite of Prasugrel. R-138727 belongs to the family of Phenylmethylamines. These are compounds containing a phenylmethtylamine moiety, which consists of a phenyl group substituted by an methanamine.

   

(1E,3E)-1-(4-Fluorophenyl)-2-methyl-1-penten-3-one oxime

N-[1-(4-fluorophenyl)-2-methylpent-1-en-3-ylidene]hydroxylamine

C12H14FNO (207.10593659999998)


   

1-(1-Chloroethyl)-4-fluorobenzene

L-2-Methylthiazolidine-4-carboxylic acid

C8H8ClF (158.029853)


   

1-(Difluoromethyl)-2,3,4-trifluorobenzene

1-(Difluoromethyl)-2,3,4-trifluorobenzene

C7H3F5 (182.0154898)


   
   

Fluorapacin

bis[(4-fluorophenyl)methyl]trisulfane

C14H12F2S3 (314.0069176)


   

4-Amino-N-(3-chloro-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide

4-Amino-N-(3-chloro-4-fluorophenyl)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide

C9H7ClFN5O2 (271.0272284)


   

7-[(4-Fluorophenyl)methoxy]-2,3-dimethyl-1-[(2-methylcyclopropyl)methyl]pyrrolo[2,3-d]pyridazine

7-[(4-fluorophenyl)methoxy]-2,3-dimethyl-1-[(2-methylcyclopropyl)methyl]-1H-pyrrolo[2,3-d]pyridazine

C20H22FN3O (339.1746814)


   

Atreleuton

1-(4-{5-[(4-fluorophenyl)methyl]thiophen-2-yl}but-3-yn-2-yl)-1-hydroxyurea

C16H15FN2O2S (318.0838222)


   

4-(4-Fluorobenzyl)-2-p-tolyl-1,2,4-thiadiazolidine-3,5-dione

4-[(4-fluorophenyl)methyl]-2-(4-methylphenyl)-1,2,4-thiadiazolidine-3,5-dione

C16H13FN2O2S (316.068173)


   

{1-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4-sulfanylpiperidin-3-ylidene}acetic acid

2-{1-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4-sulphanylpiperidin-3-ylidene}acetic acid

C18H20FNO3S (349.1147862)


   

Fenozan 50F

6,7a-bis(4-fluorophenyl)-7,7a-dihydro-4aH-spiro[cyclopenta[e][1,2,4]trioxine-3,1-cyclopentane]

C22H20F2O3 (370.1380434)


   

Fosfluconazole

[2-(2,4-Difluorophenyl)-1,3-bis(1,2,4-triazol-1-yl)propan-2-yl] dihydrogen phosphoric acid

C13H13F2N6O4P (386.07039320000007)


D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D065088 - Steroid Synthesis Inhibitors D004791 - Enzyme Inhibitors > D065088 - Steroid Synthesis Inhibitors > D058888 - 14-alpha Demethylase Inhibitors D004791 - Enzyme Inhibitors > D065607 - Cytochrome P-450 Enzyme Inhibitors C254 - Anti-Infective Agent > C514 - Antifungal Agent

   

7-(2-Chloro-6-fluorophenyl)-5-(4-chlorophenyl)-1,5,6,7-tetrahydrotetrazolo[1,5-a]pyrimidine

7-(2-chloro-6-fluorophenyl)-5-(4-chlorophenyl)-4H,5H,6H,7H-[1,2,3,4]tetrazolo[1,5-a]pyrimidine

C16H12Cl2FN5 (363.0453744)


   

Hexafluorobenzene

1,2,3,4,5,6-Hexafluorobenzene

C6F6 (185.9904192)


   

o-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine

O-[(2,3,4,5,6-pentafluorophenyl)methyl]hydroxylamine

C7H4F5NO (213.0213034)


   

Pentafluorobenzene

1,2,3,4,5-pentafluorobenzene

C6HF5 (167.9998406)


   

Pentafluorophenyl isothiocyanate

1,2,3,4,5-pentafluoro-6-isothiocyanatobenzene

C7F5NS (224.96716199999997)


   

2-[1-(2-Fluorophenyl)ethylamino]-5-methyl-5-(trifluoromethyl)-1,3-thiazol-4-one

2-{[1-(2-fluorophenyl)ethyl]imino}-5-methyl-5-(trifluoromethyl)-1,3-thiazolidin-4-one

C13H12F4N2OS (320.060643)


   

1-[[Difluoro-(2,3,4-trifluorophenyl)methoxy]-difluoromethyl]-2,3,4-trifluorobenzene

1-[[Difluoro-(2,3,4-trifluorophenyl)methoxy]-difluoromethyl]-2,3,4-trifluorobenzene

C14H4F10O (378.0102454)