Classification Term: 3230

Tyrosols and derivatives (ontology term: CHEMONTID:0000139)

Compounds containing a hydroxyethyl group attached to the C4 carbon of a phenol group." []

found 13 associated metabolites at sub_class metabolite taxonomy ontology rank level.

Ancestor: Phenols

Child Taxonomies: Tyrosol esters, Tyrosols

Betaxolol

1-(4-(2-(Cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-2-propanol

C18H29NO3 (307.2147324)


Betaxolol is only found in individuals that have used or taken this drug. It is a cardioselective beta-1-adrenergic antagonist with no partial agonist activity. [PubChem]Betaxolol selectively blocks catecholamine stimulation of beta(1)-adrenergic receptors in the heart and vascular smooth muscle. This results in a reduction of heart rate, cardiac output, systolic and diastolic blood pressure, and possibly reflex orthostatic hypotension. Betaxolol can also competitively block beta(2)-adrenergic responses in the bronchial and vascular smooth muscles, causing bronchospasm. C - Cardiovascular system > C07 - Beta blocking agents > C07A - Beta blocking agents > C07AB - Beta blocking agents, selective S - Sensory organs > S01 - Ophthalmologicals > S01E - Antiglaucoma preparations and miotics > S01ED - Beta blocking agents C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D013565 - Sympatholytics D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents Betaxolol is a selective beta1 adrenergic receptor blocker that can be used for the research of hypertension and glaucoma.

   

Metoprolol

1-[4-(2-methoxyethyl)phenoxy]-3-[(propan-2-yl)amino]propan-2-ol

C15H25NO3 (267.18343400000003)


Metoprolol is a selective beta1 receptor blocker used in treatment of several diseases of the cardiovascular system. It is marketed under the brand name Lopressor by Novartis, and Toprol (in the USA); Seleken or Selokeen (elsewhere); A selective adrenergic beta-1-blocking agent with no stimulatory action. Its binding to plasma albumin is weaker than alprenolol and it may be useful in the treatment of several diseases of the cardiovascular system; Metoprolol is a selective beta1 receptor blocker used in treatment of several diseases of the cardiovascular system. It is marketed under the brand name Lopressor by Novartis, and Toprol (in the USA); Seleken or Selokeen (elsewhere); as Minax by Alphapharm (in Australia), as Betaloc by AstraZeneca and as Corvitol by Berlin-Chemie AG; A selective adrenergic beta-1-blocking agent with no stimulatory action. Its binding to plasma albumin is weaker than alprenolol and it may be useful in angina pectoris, hypertension, or cardiac arrhythmias; as Minax by Alphapharm (in Australia), as Betaloc by AstraZeneca and as Corvitol by Berlin-Chemie AG. C - Cardiovascular system > C07 - Beta blocking agents > C07A - Beta blocking agents > C07AB - Beta blocking agents, selective C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D013565 - Sympatholytics D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents Metoprolol is an orally active, selective β1-adrenoceptor antagonist. Metoprolol shows anti-inflammation, antitumor and anti-angiogenic properties[1][2][3].

   

Oleacein

2-(3,4-Dihydroxyphenyl)ethyl (4Z)-4-formyl-3-(2-oxoethyl)hex-4-enoic acid

C17H20O6 (320.125982)


Constituent of Olea europaea (olive)and is) also from Jasminum grandiflorum (Royal jasmine). Oleacein is found in many foods, some of which are green vegetables, tea, herbs and spices, and olive. Oleacein is found in fats and oils. Oleacein is a constituent of Olea europaea (olive). Also from Jasminum grandiflorum (Royal jasmine).

   

2-(3,4-Dihydroxyphenylethyl)-6-epi-elenaiate

Methyl 4-{2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl}-3-formyl-2-methyl-3,4-dihydro-2H-pyran-5-carboxylic acid

C19H22O8 (378.1314612)


2-(3,4-Dihydroxyphenylethyl)-6-epi-elenaiate is found in fruits. 2-(3,4-Dihydroxyphenylethyl)-6-epi-elenaiate is isolated from olive leaves (Olea europaea). Isolated from leaves of Olea europaea (olive). (3,4-Dihydroxyphenylethyl)-elenaiate is found in herbs and spices and fruits.

   

p-HPEA-EDA

2-(4-Hydroxyphenyl)ethyl (4E)-4-formyl-3-(2-oxoethyl)hex-4-enoic acid

C17H20O5 (304.13106700000003)


p-HPEA-EDA is the major form of the decarboxymethyl ligstroside-aglycone. p-HPEA-EDA is found in olive. p-HPEA-EDA is found in olive. p-HPEA-EDA is the major form of the decarboxymethyl ligstroside-aglycone

   

Etrogol

2-{4-[(3-methylbut-2-en-1-yl)oxy]phenyl}ethan-1-ol

C13H18O2 (206.1306728)


Isolated from the roots of Citrus subspecies Etrogol is found in sweet orange and citrus. Etrogol is found in citrus. Etrogol is isolated from the roots of Citrus species.

   

3'-Deoxyoleacein

2-(4-Hydroxyphenyl)ethyl (4Z)-4-formyl-3-(2-oxoethyl)hex-4-enoic acid

C17H20O5 (304.13106700000003)


Constituent of Olea europaea (olive). 3-Deoxyoleacein is found in fats and oils, herbs and spices, and fruits. 3-Deoxyoleacein is found in fats and oils. 3-Deoxyoleacein is a constituent of Olea europaea (olive).

   

Hydroxytyrosol Acetate

2-(3,4-dihydroxyphenyl)ethyl acetate

C10H12O4 (196.0735552)


Hydroxytyrosol acetate belongs to tyrosols and derivatives class of compounds. Those are compounds containing a hydroxyethyl group attached to the C4 carbon of a phenol group. Hydroxytyrosol acetate is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Hydroxytyrosol acetate can be found in olive, which makes hydroxytyrosol acetate a potential biomarker for the consumption of this food product. Hydroxytyrosol acetate is found in the olive oil with an antioxidant activity. Hydroxytyrosol acetate had a weaker DPPH radical scavenging activity?than hydroxytyrosol[1]. Hydroxytyrosol acetate is found in the olive oil with an antioxidant activity. Hydroxytyrosol acetate had a weaker DPPH radical scavenging activity?than hydroxytyrosol[1].

   

O-Demethylmetoprolol

1-[4-(2-hydroxyethyl)phenoxy]-3-[(propan-2-yl)amino]propan-2-ol

C14H23NO3 (253.1677848)


   

Oleocanthal

2-(4-Hydroxyphenyl)ethyl 4-formyl-3-(2-oxoethyl)hex-4-enoic acid

C17H20O5 (304.13106700000003)


   

Vernakalant

1-[2-[2-(3,4-Dimethoxyphenyl)ethoxy]cyclohexyl]pyrrolidin-3-ol

C20H31NO4 (349.22529660000004)


   

Oxyresveratrol (cis-)

2-(4-hydroxyphenyl)ethyl (3S)-4-formyl-3-(2-oxoethyl)hex-4-enoate

C17H20O5 (304.13106700000003)


   

2-(4-Methoxyphenyl)ethyl hydrogen sulfate

2-(4-Methoxyphenyl)ethyl hydrogen sulphuric acid

C9H12O5S (232.04054219999998)