Classification Term: 3178

Anthracenecarboxylic acids (ontology term: CHEMONTID:0002424)

Organic compounds containing a carboxylic acid group attached to an anthracene ring system." []

found 25 associated metabolites at category metabolite taxonomy ontology rank level.

Ancestor: Anthracenecarboxylic acids and derivatives

Child Taxonomies: There is no child term of current ontology term.

Carmine red

3,5,6,8-tetrahydroxy-1-methyl-9,10-dioxo-7-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-9,10-dihydroanthracene-2-carboxylic acid

C22H20O13 (492.0904)


Red food colouring The source of this color is a picture of a "deep carmine pink" flower at the following website:; The source of this color is a watercolor color swatch called light carmine displayed at the following website: Isolated from cochineal, obtained from the dried female bodies of the insect Dactylopius coccus. Dyestuff, red food colouring. [CCD]. D000074385 - Food Ingredients > D005503 - Food Additives > D005505 - Food Coloring Agents D004396 - Coloring Agents

   

Rhein

4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid

C15H8O6 (284.0321)


Rhein appears as yellow needles (from methanol) or yellow-brown powder. (NTP, 1992) Rhein is a dihydroxyanthraquinone. Rhein is an anthraquinone metabolite of rheinanthrone and senna glycoside is present in many medicinal plants including Rheum palmatum, Cassia tora, Polygonum multiflorum, and Aloe barbadensis. It is known to have hepatoprotective, nephroprotective, anti-cancer, anti-inflammatory, and several other protective effects. Rhein is a natural product found in Cassia renigera, Rheum compactum, and other organisms with data available. Present in Rheum palmatum (Chinese rhubarb). Rhein is found in dock, green vegetables, and garden rhubarb. Rhein is found in dock. Rhein is present in Rheum palmatum (Chinese rhubarb D004791 - Enzyme Inhibitors KEIO_ID R037

   

Sennoside B

(9S)-9-[(9R)-2-carboxy-4-hydroxy-10-oxo-5-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-9,10-dihydroanthracen-9-yl]-4-hydroxy-10-oxo-5-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-9,10-dihydroanthracene-2-carboxylic acid

C42H38O20 (862.1956)


Sennoside B is an anthranoid. Anthranoid derivatives are used all over the world as a treatment for constipation. These compounds are present in several drugs of plant origin, especially as O- or C-glycosides. Besides featuring different substituents, the aglycone might consist of an anthraquinone, an anthrone or a dianthrone. So far, detailed information concerning their metabolism and pharmacokinetic characteristics is available only in a few cases. The best characterized compounds are sennoside, a dianthrone O-glycoside present in senna leaves and senna pods, and its aglycone (rhein anthrone). After oral administration, sennoside is degraded only in the lower parts of the gastrointestinal tract, releasing its active metabolite rhein anthrone. (PMID: 8234447). Sennoside B is found in garden rhubarb. Sennoside B is an anthranoid. Anthranoid derivatives are used all over the world as a treatment for constipation. These compounds are present in several drugs of plant origin, especially as O- or C-glycosides. Besides featuring different substituents, the aglycone might consist of an anthraquinone, an anthrone or a dianthrone. So far, detailed information concerning their metabolism and pharmacokinetic characteristics is available only in a few cases. The best characterized compounds are sennoside, a dianthrone O-glycoside present in senna leaves and senna pods, and its aglycone (rhein anthrone). After oral administration, sennoside is degraded only in the lower parts of the gastrointestinal tract, releasing its active metabolite rhein anthrone. (PMID: 8234447). Sennoside B is a member of the class of sennosides that is (9R,9S)-9,9,10,10-tetrahydro-9,9-bianthracene-2,2-dicarboxylic acid which is substituted by hydroxy groups at positions 4 and 4, by beta-D-glucopyranosyloxy groups at positions 5 and 5, and by oxo groups at positions 10 and 10. It is a member of sennosides and an oxo dicarboxylic acid. Sennoside B is a natural product found in Rheum palmatum, Rheum tanguticum, and other organisms with data available. A member of the class of sennosides that is (9R,9S)-9,9,10,10-tetrahydro-9,9-bianthracene-2,2-dicarboxylic acid which is substituted by hydroxy groups at positions 4 and 4, by beta-D-glucopyranosyloxy groups at positions 5 and 5, and by oxo groups at positions 10 and 10.

   

anthracene-9-carboxylic acid

9-Anthroic acid, sodium salt, 11C-labeled

C15H10O2 (222.0681)


CONFIDENCE standard compound; INTERNAL_ID 8026

   

Glucorhein

4-hydroxy-9,10-dioxo-5-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-9,10-dihydroanthracene-2-carboxylic acid

C21H18O11 (446.0849)


Glucorhein is found in green vegetables. Glucorhein is isolated from Rheum palmatum (Chinese rhubarb). Isolated from Rheum palmatum (Chinese rhubarb). Glucorhein is found in green vegetables. Rhein 8-Glucoside (Rhein 8-O-β-D-Glucopyranoside) is an anthraquinone glycoside that has been found in rhubarb. Purgative activity[1]. Rhein 8-Glucoside (Rhein 8-O-β-D-Glucopyranoside) is an anthraquinone glycoside that has been found in rhubarb. Purgative activity[1].

   

(3beta,4alpha,5alpha)-4,14-Dimethylergosta-9(11),24(28)-dien-3-ol

2,6,11,15-tetramethyl-14-(6-methyl-5-methylideneheptan-2-yl)tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-1(17)-en-5-ol

C30H50O (426.3861)


(3beta,4alpha,5alpha)-4,14-Dimethylergosta-9(11),24(28)-dien-3-ol is found in pulses. (3beta,4alpha,5alpha)-4,14-Dimethylergosta-9(11),24(28)-dien-3-ol is isolated from seeds of Phaseolus vulgaris (kidney bean).

   

Sennidin C

9-[4,5-dihydroxy-2-(hydroxymethyl)-10-oxo-9,10-dihydroanthracen-9-yl]-4,5-dihydroxy-10-oxo-9,10-dihydroanthracene-2-carboxylic acid

C30H20O9 (524.1107)


Sennidin C is found in green vegetables. Aglycone from Sennoside C. It is isolated from Chinese rhubarb (Rheum palmatum Aglycone from Sennoside C. Isolated from Chinese rhubarb (Rheum palmatum). Sennidin C is found in green vegetables.

   

Rheidin A

4,5-dihydroxy-10-oxo-9-(2,4,5-trihydroxy-7-methyl-10-oxo-9,10-dihydroanthracen-9-yl)-9,10-dihydroanthracene-2-carboxylic acid

C30H20O9 (524.1107)


Rheidin A is found in green vegetables. Rheidin A is isolated from Turkey rhubarb. Isolated from Turkey rhubarb. Rheidin A is found in green vegetables.

   

Rheinoside A

4,9-dihydroxy-10-oxo-9-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-5-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-9,10-dihydroanthracene-2-carboxylic acid

C27H30O16 (610.1534)


Rheinoside B is found in green vegetables. Rheinoside B is a constituent of rhubarb. Constituent of rhubarb (Rheum species). Rheinoside A is found in green vegetables.

   

Sennidin B

(9S)-9-[(9R)-2-carboxy-4,5-dihydroxy-10-oxo-9,10-dihydroanthracen-9-yl]-4,5-dihydroxy-10-oxo-9,10-dihydroanthracene-2-carboxylic acid

C30H18O10 (538.09)


Anthraquinone derivative, a stereoisomer of sennidin A, stimulates glucose incoporation into adipocytes in rats, but the activity of sennidin B is lower than sennidin A. [HMDB] Anthraquinone derivative, a stereoisomer of sennidin A, stimulates glucose incoporation into adipocytes in rats, but the activity of sennidin B is lower than sennidin A.

   

3,8-Dihydroxy-1-methylanthraquinone-2-carboxylic acid

9,10-dihydro-3,8-Dihydroxy-1-methyl-9,10-dioxo-2-anthracenecarboxylic acid, 9ci

C16H10O6 (298.0477)


3,8-Dihydroxy-1-methylanthraquinone-2-carboxylic acid is found in saffron. 3,8-Dihydroxy-1-methylanthraquinone-2-carboxylic acid is a constituent of Crocus sativus (saffron) Constituent of Crocus sativus (saffron). 3,8-Dihydroxy-1-methylanthraquinone-2-carboxylic acid is found in saffron.

   

Rheinanthrone

4,5-dihydroxy-10-oxo-9,10-dihydroanthracene-2-carboxylic acid

C15H10O5 (270.0528)


Rheinanthrone is found in green vegetables. Rheinanthrone is produced from Rheum species. Production from Rheum subspecies Rheinanthrone is found in green vegetables.

   

Rheidin C

9-(4,5-dihydroxy-2-methoxy-7-methyl-10-oxo-9,10-dihydroanthracen-9-yl)-4,5-dihydroxy-10-oxo-9,10-dihydroanthracene-2-carboxylic acid

C31H22O9 (538.1264)


Rheidin C is found in green vegetables. Rheidin C is isolated from rhubarb roots. Isolated from rhubarb roots. Rheidin C is found in green vegetables.

   

Smilagenin 3-[2'-glucosyl-6'-arabinosylglucoside]

2-[(4,5-dihydroxy-2-{5,7,9,13-tetramethyl-5-oxaspiro[oxane-2,6-pentacyclo[10.8.0.0²,⁹.0⁴,⁸.0¹³,¹⁸]icosane]oxy}-6-{[(3,4,5-trihydroxyoxan-2-yl)oxy]methyl}oxan-3-yl)oxy]-6-(hydroxymethyl)oxane-3,4,5-triol

C44H72O17 (872.4769)


Smilagenin 3-[2-glucosyl-6-arabinosylglucoside] is found in green vegetables. Smilagenin 3-[2-glucosyl-6-arabinosylglucoside] is a constituent of the wild asparagus (Asparagus africanus)

   

Rheidin B

9-(4,5-dihydroxy-2-methyl-10-oxo-9,10-dihydroanthracen-9-yl)-4,5-dihydroxy-10-oxo-9,10-dihydroanthracene-2-carboxylic acid

C30H20O8 (508.1158)


Rheidin B is found in green vegetables. Rheidin B is isolated from rhubarb roots. Isolated from rhubarb roots. Rheidin B is found in green vegetables.

   

Laccaic acid D

9,10-Dihydro-3,6,8-trihydroxy-1-methyl-9,10-dioxo-2-anthracenecarboxylic acid, 9ci

C16H10O7 (314.0427)


Laccaic acid D is found in green vegetables. Laccaic acid D is a constituent of rhubarb rhizomes

   

Rhamnalpinogenin

6,8-dihydroxy-3-methoxy-1-methyl-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid

C17H12O7 (328.0583)


Rhamnalpinogenin is a constituent of Crocus sativus (saffron)

   

Sennoside E

(9R)-9-[(9R)-2-carboxy-5-{[(2S,3R,4S,5S,6R)-3-[(carboxycarbonyl)oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4-hydroxy-10-oxo-9,10-dihydroanthracen-9-yl]-4-hydroxy-10-oxo-5-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-9,10-dihydroanthracene-2-carboxylic acid

C44H38O23 (934.1804)


Sennoside E is found in green vegetables. Sennoside E is found in rhubarb. Found in rhubarb

   

Sennoside F

(9R)-9-[(9S)-2-carboxy-5-{[(2S,3R,4S,5S,6R)-3-[(carboxycarbonyl)oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4-hydroxy-10-oxo-9,10-dihydroanthracen-9-yl]-4-hydroxy-10-oxo-5-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-9,10-dihydroanthracene-2-carboxylic acid

C44H38O23 (934.1804)


Sennoside F is found in green vegetables. Sennoside F is from rhubarb Sennoside F is found in green vegetables. Sennoside F is from rhubar

   

8-Hydroxy-3-methoxy-1-methylanthraquinone-2-carboxylic acid

8-hydroxy-3-methoxy-1-methyl-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid

C17H12O6 (312.0634)


8-Hydroxy-3-methoxy-1-methylanthraquinone-2-carboxylic acid is a constituent of Crocus sativus (saffron). Constituent of Crocus sativus (saffron)

   

Carminomycin II

8-acetyl-10-[(4-amino-5-{3-hydroxy-1-[(1-hydroxypropan-2-yl)oxy]butoxy}-6-methyloxan-2-yl)oxy]-1,6,8,11-tetrahydroxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione

C33H41NO13 (659.2578)


D000970 - Antineoplastic Agents > D059003 - Topoisomerase Inhibitors > D059005 - Topoisomerase II Inhibitors D004791 - Enzyme Inhibitors

   

Diacerein

4,5-bis(acetyloxy)-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid

C19H12O8 (368.0532)


M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01A - Antiinflammatory and antirheumatic products, non-steroids COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials C78281 - Agent Affecting Musculoskeletal System D000893 - Anti-Inflammatory Agents Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Diacerein (Diacerhein), a interleukin-1 beta inhibitor, is a slow-acting medicine of the class anthraquinone used to treat joint diseases. Diacerein (Diacerhein), a interleukin-1 beta inhibitor, is a slow-acting medicine of the class anthraquinone used to treat joint diseases.

   

Munjistin

1,3-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid

C15H8O6 (284.0321)


   

Rangbatti

7-acetyl-6-ethyl-3,5,8-trihydroxy-9,10-dioxo-9,10-dihydroanthracene-1,2-dicarboxylic acid

C20H14O10 (414.0587)


   

Sennaglucosides

9-(2-carboxy-4-hydroxy-10-oxo-5-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-9,10-dihydroanthracen-9-yl)-4-hydroxy-10-oxo-5-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-9,10-dihydroanthracene-2-carboxylic acid

C42H38O20 (862.1956)