Classification Term: 269

Piperidinediones (ontology term: CHEMONTID:0001582)

Compounds containing a piperidine ring which bears two ketones." []

found 4 associated metabolites at category metabolite taxonomy ontology rank level.

Ancestor: Piperidinones

Child Taxonomies: There is no child term of current ontology term.

Methyprylon

3,3-diethyl-5-methylpiperidine-2,4-dione

C10H17NO2 (183.12592220000002)


Methyprylon is a sedative of the piperidinedione derivative family. This medicine was used for treating insomnia, but is now rarely used as it has been replaced by newer drugs with less side effects, such as benzodiazepines. Methyprylon was withdrawn from the US market in June 1965 and the Canadian market in September 1990. [Wikipedia] N - Nervous system > N05 - Psycholeptics > N05C - Hypnotics and sedatives > N05CE - Piperidinedione derivatives C78272 - Agent Affecting Nervous System > C29756 - Sedative and Hypnotic

   

bemegride

4-ethyl-6-hydroxy-4-methyl-2,3,4,5-tetrahydropyridin-2-one

C8H13NO2 (155.0946238)


R - Respiratory system > R07 - Other respiratory system products > R07A - Other respiratory system products > R07AB - Respiratory stimulants D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants > D003292 - Convulsants C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant D019141 - Respiratory System Agents Bemegride (3-Ethyl-3-methylglutarimide) is a central nervous system stimulant and antidote for barbiturate poisoning[1][2].

   

Cycloheximide

4-[2-(3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]piperidine-2,6-dione

C15H23NO4 (281.1626998)


   

Rogletimide

(+)-TRANS-1,2-CYCLOHEXANEDICARBOXYLICANHYDRIDE

C12H14N2O2 (218.1055224)


C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C274 - Antineoplastic Agent > C129818 - Antineoplastic Hormonal/Endocrine Agent > C481 - Antiestrogen C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C1740 - Aromatase Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor C147908 - Hormone Therapy Agent > C547 - Hormone Antagonist