Classification Term: 2136

Cinnamylphenols (ontology term: CHEMONTID:0003496)

Organic compounds containing the 1,3-diphenylpropene moiety with one benzene ring bearing one or more hydroxyl groups." [PMID:14695799]

found 8 associated metabolites at sub_class metabolite taxonomy ontology rank level.

Ancestor: Linear 1,3-diarylpropanoids

Child Taxonomies: There is no child term of current ontology term.

2'-O-Methylisoliquiritigenin

(2E)-1-(4-Hydroxy-2-methoxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one

C16H14O4 (270.0892)


2-O-Methylisoliquiritigenin (CAS: 51828-10-5), also known as 4,4-dihydroxy-2-methoxychalcone or 3-deoxysappanchalcone, belongs to the class of organic compounds known as cinnamylphenols. These are organic compounds containing the 1,3-diphenylpropene moiety with one benzene ring bearing one or more hydroxyl groups. Thus, 2-O-methylisoliquiritigenin is considered to be a flavonoid lipid molecule. 2-O-Methylisoliquiritigenin is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral. 2-O-Methylisoliquiritigenin is a stress metabolite of Pisum sativum (pea). Stress metabolite of Pisum sativum (pea). 2-Methylisoliquiritigenin is found in pulses and common pea. 2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-regulates 5-HT, NE, DA and GABA pathways, but does not put a very significant effect on ne NE pathway[1]. 2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-regulates 5-HT, NE, DA and GABA pathways, but does not put a very significant effect on ne NE pathway[1]. 2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-regulates 5-HT, NE, DA and GABA pathways, but does not put a very significant effect on ne NE pathway[1].

   

Xenognosin A

4-[(2E)-3-(4-hydroxyphenyl)prop-2-en-1-yl]-3-methoxyphenol

C16H16O3 (256.1099)


Xenognosin A is found in common pea. Xenognosin A is isolated from gum tragacanth. Xenognosin A is a stress metabolite of pea (Pisum sativum Isolated from gum tragacanth. Stress metabolite of pea (Pisum sativum). Xenognosin A is found in pulses and common pea.

   

4,4'-Dihydroxy-2',6'-dimethoxychalcone

(2E)-1-(4-hydroxy-2,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one

C17H16O5 (300.0998)


4,4-Dihydroxy-2,6-dimethoxychalcone is found in alcoholic beverages. 4,4-Dihydroxy-2,6-dimethoxychalcone is isolated from Humulus lupulus (hops). Isolated from Humulus lupulus (hops). 4,4-Dihydroxy-2,6-dimethoxychalcone is found in alcoholic beverages.

   

Obtustyrene

3-methoxy-4-[(2E)-3-phenylprop-2-en-1-yl]phenol

C16H16O2 (240.115)


Obtustyrene is found in common pea. Obtustyrene is a stress metabolite of pe Stress metabolite of pea. Obtustyrene is found in pulses and common pea.

   

5-hydroxypropafenone

1-{5-hydroxy-2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one

C21H27NO4 (357.194)


5-hydroxypropafenone is a metabolite of propafenone. Propafenone is a class of anti-arrhythmic medication, which treats illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias. (Wikipedia) D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents

   

10-alpha-methoxy-9,10-dihydrolysergol

[(4R)-2-methoxy-6-methyl-6,11-diazatetracyclo[7.6.1.0²,⁷.0¹²,¹⁶]hexadeca-1(16),9,12,14-tetraen-4-yl]methanol

C17H22N2O2 (286.1681)


10-alpha-methoxy-9,10-dihydrolysergol is a metabolite of nicergoline. Nicergoline (marketed under the trade name Sermion) is an ergot derivative used to treat senile dementia and other disorders with vascular origins. It has been found to increase mental agility and enhance clarity and perception. It decreases vascular resistance and increases arterial blood flow in the brain, improving the utilization of oxygen and glucose by brain cells. It has similar vasoactive properties in other areas of the body, particularly the lungs. (Wikipedia)

   

Eplivanserin

4-((3Z)-3-(2-Dimethylaminoethyl)oxyimino-3-(2-fluorophenyl)propen-1-yl)phenol hemifumarate

C19H21FN2O2 (328.1587)


   

N-(3-Phenylpropyl)-3,4-dihydroxybenzylidene cyanoacetamide

2,2,4,4-tetracyano-N-{[3,4-dihydroxy-2-(3-phenylpropyl)phenyl]methylidene}-3-oxobutanamide

C24H17N5O4 (439.128)


D000970 - Antineoplastic Agents > D020032 - Tyrphostins