Classification Term: 170552

Thujane monoterpenoids (ontology term: c421aa56147398b48298f29404a568e0)

found 68 associated metabolites at sub_class metabolite taxonomy ontology rank level.

Ancestor: Monoterpenoids

Child Taxonomies: There is no child term of current ontology term.

(-)-Sabinene

(1R,5R)-4-methylidene-1-(propan-2-yl)bicyclo[3.1.0]hexane (1R,5R)-thuj-4(10)-ene

C10H16 (136.1251936)


Sabinene (CAS: 3387-41-5) belongs to the class of organic compounds known as bicyclic monoterpenoids. These are monoterpenoids containing exactly 2 rings, which are fused to each other. Thus, sabinene is considered to be an isoprenoid lipid molecule. Sabinene is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral. (-)-Sabinene is found in herbs and spices and is a constituent of Laurus nobilis (bay laurel). Constituent of Laurus nobilis (bay laurel) and some other plants. (-)-4(10)-Thujene is found in sweet bay and herbs and spices. Sabinene is a thujene that is a bicyclic monoterpene isolated from the essential oils of various plant species. It has a role as a plant metabolite. Black pepper allergenic extract is used in allergenic testing. Laurus nobilis allergenic extract is used in allergenic testing. Nutmeg allergenic extract is used in allergenic testing. Sabinene is a natural product found in Teucrium montanum, Xylopia aromatica, and other organisms with data available. Carrot Seed Oil is the oil extracted from the seeds of Daucus carota. Carrot seed oil is primarily used in skin treatment preparations. Acquisition and generation of the data is financially supported in part by CREST/JST. Sabinene is an naturally occurring bicyclic monoterpene which can be used as flavorings, perfume additives, fine chemicals, and advanced biofuels. Sabinene is also an orally active compound to attenuates skeletal muscle atrophy and regulates ROS-mediated MAPK/MuRF-1 pathways[1][2]. Sabinene is an naturally occurring bicyclic monoterpene which can be used as flavorings, perfume additives, fine chemicals, and advanced biofuels. Sabinene is also an orally active compound to attenuates skeletal muscle atrophy and regulates ROS-mediated MAPK/MuRF-1 pathways[1][2].

   

Umbellulone

[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one

C10H14O (150.1044594)


Umbellulone is a ketone. (-)-Umbellulone is a natural product found in Tanacetum vulgare, Pimenta racemosa, and Umbellularia californica with data available.

   

Thujyl alcohol

(1S,3S,4S,5R)-4-methyl-1-(propan-2-yl)bicyclo[3.1.0]hexan-3-ol

C10H18O (154.1357578)


Thujyl alcohol is used as a food additive [EAFUS] ("EAFUS: Everything Added to Food in the United States. [http://www.eafus.com/]")

   

(+)-Sabinene

(1R,5R)-4-methylidene-1-(propan-2-yl)bicyclo[3.1.0]hexane

C10H16 (136.1251936)


Sabinene (CAS: 3387-41-5) belongs to the class of organic compounds known as bicyclic monoterpenoids. These are monoterpenoids containing exactly 2 rings, which are fused to each other. Thus, sabinene is considered to be an isoprenoid lipid molecule. Sabinene is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral. (+)-Sabinene, also known as (+)-4(10)-thujene, is found in common sage and Myristica fragrans (nutmeg).

   

(-)-3-Thujone

(1R,4R,5S)-4-methyl-1-(propan-2-yl)bicyclo[3.1.0]hexan-3-one

C10H16O (152.12010859999998)


Thujone is a ketone and a monoterpene that occurs naturally in two diastereomeric forms: (-)-alpha-thujone and (+)-beta-thujone. It has a menthol odor. In addition to (-)-alpha-thujone and (+)-beta-thujone, there are their enantiomeric forms, (+)-alpha-thujone and (-)-beta-thujone. (Wikipedia Thujone is a ketone and a monoterpene that occurs naturally in two diastereomeric forms: (-)-alpha-thujone and (+)-beta-thujone. It has a menthol odor. In addition to (-)-alpha-thujone and (+)-beta-thujone, there are their enantiomeric forms, (+)-alpha-thujone and (-)-beta-thujone.

   

cis-Sabinene hydrate acetate

(2R,5S)-2-methyl-5-(propan-2-yl)bicyclo[3.1.0]hexan-2-yl acetate

C12H20O2 (196.14632200000003)


Cis-sabinene hydrate acetate is also known as cis-sabinene hydric acid acetic acid. Cis-sabinene hydrate acetate is practically insoluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Cis-sabinene hydrate acetate can be found in sweet marjoram, which makes cis-sabinene hydrate acetate a potential biomarker for the consumption of this food product.

   

cis-Thujanol

(1R,3R)-4-methyl-1-(propan-2-yl)bicyclo[3.1.0]hexan-3-ol

C10H18O (154.1357578)


Cis-thujanol is a member of the class of compounds known as bicyclic monoterpenoids. Bicyclic monoterpenoids are monoterpenoids containing exactly 2 rings, which are fused to each other. Cis-thujanol is practically insoluble (in water) and an extremely weak acidic compound (based on its pKa). Cis-thujanol can be found in pot marjoram, which makes cis-thujanol a potential biomarker for the consumption of this food product.

   

beta-Thujene

4-methyl-1-(propan-2-yl)bicyclo[3.1.0]hex-2-ene

C10H16 (136.1251936)


Beta-thujene, also known as beta-thujene, is a member of the class of compounds known as bicyclic monoterpenoids. Bicyclic monoterpenoids are monoterpenoids containing exactly 2 rings, which are fused to each other. Beta-thujene can be found in rosemary, which makes beta-thujene a potential biomarker for the consumption of this food product. Beta-thujene, also known as β-thujene, is a member of the class of compounds known as bicyclic monoterpenoids. Bicyclic monoterpenoids are monoterpenoids containing exactly 2 rings, which are fused to each other. Beta-thujene can be found in rosemary, which makes beta-thujene a potential biomarker for the consumption of this food product.

   

Sabinyl acetate

4-methylidene-1-(propan-2-yl)bicyclo[3.1.0]hexan-3-yl acetate

C12H18O2 (194.1306728)


Sabinyl acetate, also known as sabinyl acetic acid or sabinyl acetate, (1alpha,3beta,5alpha)-isomer, is a member of the class of compounds known as bicyclic monoterpenoids. Bicyclic monoterpenoids are monoterpenoids containing exactly 2 rings, which are fused to each other. Sabinyl acetate is practically insoluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Sabinyl acetate can be found in common sage and rosemary, which makes sabinyl acetate a potential biomarker for the consumption of these food products.

   

Thujone

Bicyclo[3.1.0]hexan-3-one,4-methyl-1-(1-methylethyl)-

C10H16O (152.12010859999998)


α-Thujone is a monoterpene isolated from Thuja occidentalis essential oil with potent anti-tumor activities. α-Thujone is a reversible modulator of the GABA type A receptor and the IC50 for α-Thujone is 21 μM in suppressing the GABA-induced currents. α-Thujone induces ROS accumulation-dependent cytotoxicity, also induces cell apoptosis and autophagy. α-Thujone has antinociceptive, insecticidal, and anthelmintic activity, and easily penetrates the blood-brain barrier[1][2][3]. α-Thujone is a monoterpene isolated from Thuja occidentalis essential oil with potent anti-tumor activities. α-Thujone is a reversible modulator of the GABA type A receptor and the IC50 for α-Thujone is 21 μM in suppressing the GABA-induced currents. α-Thujone induces ROS accumulation-dependent cytotoxicity, also induces cell apoptosis and autophagy. α-Thujone has antinociceptive, insecticidal, and anthelmintic activity, and easily penetrates the blood-brain barrier[1][2][3]. α-Thujone is a monoterpene isolated from Thuja occidentalis essential oil with potent anti-tumor activities. α-Thujone is a reversible modulator of the GABA type A receptor and the IC50 for α-Thujone is 21 μM in suppressing the GABA-induced currents. α-Thujone induces ROS accumulation-dependent cytotoxicity, also induces cell apoptosis and autophagy. α-Thujone has antinociceptive, insecticidal, and anthelmintic activity, and easily penetrates the blood-brain barrier[1][2][3].

   

4-Isopropyl-1-methylbicyclo[3.1.0]hexan-2-one

4-Isopropyl-1-methylbicyclo[3.1.0]hexan-2-one

C10H16O (152.12010859999998)


   
   

Sabinene

Bicyclo[3.1.0]hexane, 4-methylene-1-(1-methylethyl)-

C10H16 (136.1251936)


Sabinene is a thujene that is a bicyclic monoterpene isolated from the essential oils of various plant species. It has a role as a plant metabolite. Black pepper allergenic extract is used in allergenic testing. Laurus nobilis allergenic extract is used in allergenic testing. Nutmeg allergenic extract is used in allergenic testing. Sabinene is a natural product found in Teucrium montanum, Xylopia aromatica, and other organisms with data available. Carrot Seed Oil is the oil extracted from the seeds of Daucus carota. Carrot seed oil is primarily used in skin treatment preparations. A thujene that is a bicyclic monoterpene isolated from the essential oils of various plant species. 4(10)-thujene, also known as sabinen or 1-isopropyl-4-methylenebicyclo[3.1.0]hexane, is a member of the class of compounds known as bicyclic monoterpenoids. Bicyclic monoterpenoids are monoterpenoids containing exactly 2 rings, which are fused to each other. 4(10)-thujene is a citrus, pepper, and pine tasting compound and can be found in a number of food items such as sweet orange, green bell pepper, pot marjoram, and parsley, which makes 4(10)-thujene a potential biomarker for the consumption of these food products. Sabinene is an naturally occurring bicyclic monoterpene which can be used as flavorings, perfume additives, fine chemicals, and advanced biofuels. Sabinene is also an orally active compound to attenuates skeletal muscle atrophy and regulates ROS-mediated MAPK/MuRF-1 pathways[1][2]. Sabinene is an naturally occurring bicyclic monoterpene which can be used as flavorings, perfume additives, fine chemicals, and advanced biofuels. Sabinene is also an orally active compound to attenuates skeletal muscle atrophy and regulates ROS-mediated MAPK/MuRF-1 pathways[1][2].

   

(-)-sabinene

(1S,5S)-4-methylidene-1-(propan-2-yl)bicyclo[3.1.0]hexane (1S,5S)-thuj-4(10)-ene

C10H16 (136.1251936)


   

Thujol

4-methyl-1-(propan-2-yl)bicyclo[3.1.0]hexan-3-ol

C10H18O (154.1357578)


   

Sabinaketone

5-(1-Methylethyl)bicyclo[3.1.0]hexan-2-one, 9ci

C9H14O (138.1044594)


   

(+)-sabinene

(1R,5R)-4-methylidene-1-(propan-2-yl)bicyclo[3.1.0]hexane (1R,5R)-thuj-4(10)-ene

C10H16 (136.1251936)


Constituent of Myristica fragrans (nutmeg). (+)-4(10)-Thujene is found in many foods, some of which are common sage, nutmeg, turmeric, and herbs and spices.

   

1-isopropyl-4-methoxy-4-methylbicyclo[3.1.0]hexane-2,3-diol

1-isopropyl-4-methoxy-4-methylbicyclo[3.1.0]hexane-2,3-diol

C11H20O3 (200.14123700000002)


   

(1r,3s)-1-isopropyl-4-methylidenebicyclo[3.1.0]hexan-3-yl acetate

(1r,3s)-1-isopropyl-4-methylidenebicyclo[3.1.0]hexan-3-yl acetate

C12H18O2 (194.1306728)


   

(1s,4s,5s)-1-isopropyl-4-methylbicyclo[3.1.0]hex-2-ene

(1s,4s,5s)-1-isopropyl-4-methylbicyclo[3.1.0]hex-2-ene

C10H16 (136.1251936)


   

(1r,2s,5s)-2-(hydroxymethyl)-5-isopropylbicyclo[3.1.0]hexan-2-ol

(1r,2s,5s)-2-(hydroxymethyl)-5-isopropylbicyclo[3.1.0]hexan-2-ol

C10H18O2 (170.1306728)


   

(+)-α-thujene

(+)-α-thujene

C10H16 (136.1251936)


   

(1r,2r,5s)-1-isopropyl-4-methylidenebicyclo[3.1.0]hexan-2-yl acetate

(1r,2r,5s)-1-isopropyl-4-methylidenebicyclo[3.1.0]hexan-2-yl acetate

C12H18O2 (194.1306728)


   

(1s,2r,5s)-5-isopropylbicyclo[3.1.0]hex-3-ene-2-carbaldehyde

(1s,2r,5s)-5-isopropylbicyclo[3.1.0]hex-3-ene-2-carbaldehyde

C10H14O (150.1044594)


   

5-isopropylbicyclo[3.1.0]hex-3-ene-2-carbaldehyde

5-isopropylbicyclo[3.1.0]hex-3-ene-2-carbaldehyde

C10H14O (150.1044594)


   

(2s,5s)-5-isopropyl-2-methylbicyclo[3.1.0]hexan-2-yl acetate

(2s,5s)-5-isopropyl-2-methylbicyclo[3.1.0]hexan-2-yl acetate

C12H20O2 (196.14632200000003)


   

5-isopropyl-2-methylbicyclo[3.1.0]hexan-1-ol

5-isopropyl-2-methylbicyclo[3.1.0]hexan-1-ol

C10H18O (154.1357578)


   

4-(hydroxymethyl)-1-isopropylbicyclo[3.1.0]hex-3-en-2-one

4-(hydroxymethyl)-1-isopropylbicyclo[3.1.0]hex-3-en-2-one

C10H14O2 (166.09937440000002)


   

(1r,2s,3r,4r,5r)-1-isopropyl-4-methylbicyclo[3.1.0]hexane-2,3,4-triol

(1r,2s,3r,4r,5r)-1-isopropyl-4-methylbicyclo[3.1.0]hexane-2,3,4-triol

C10H18O3 (186.1255878)


   

(1s,3s,5s)-1-isopropyl-4-methylidenebicyclo[3.1.0]hexan-3-yl acetate

(1s,3s,5s)-1-isopropyl-4-methylidenebicyclo[3.1.0]hexan-3-yl acetate

C12H18O2 (194.1306728)


   

2,2-dimethyl-3-(3-{4-methylbicyclo[3.1.0]hex-3-en-1-yl}butyl)oxirane

2,2-dimethyl-3-(3-{4-methylbicyclo[3.1.0]hex-3-en-1-yl}butyl)oxirane

C15H24O (220.18270539999997)


   

5-isopropylbicyclo[3.1.0]hex-2-ene-2-carbaldehyde

5-isopropylbicyclo[3.1.0]hex-2-ene-2-carbaldehyde

C10H14O (150.1044594)


   

(1r,5s)-1-isopropyl-4-methylbicyclo[3.1.0]hex-3-en-2-one

(1r,5s)-1-isopropyl-4-methylbicyclo[3.1.0]hex-3-en-2-one

C10H14O (150.1044594)


   

(1s,3r,4s,5r)-1-isopropyl-4-methylbicyclo[3.1.0]hexan-3-ol

(1s,3r,4s,5r)-1-isopropyl-4-methylbicyclo[3.1.0]hexan-3-ol

C10H18O (154.1357578)


   

(1r,2r,5s)-2-(hydroxymethyl)-5-isopropylbicyclo[3.1.0]hexan-2-ol

(1r,2r,5s)-2-(hydroxymethyl)-5-isopropylbicyclo[3.1.0]hexan-2-ol

C10H18O2 (170.1306728)


   

(1r,4r,5r)-4-methyl-1-[(2r)-1-{[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}propan-2-yl]bicyclo[3.1.0]hexan-3-one

(1r,4r,5r)-4-methyl-1-[(2r)-1-{[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}propan-2-yl]bicyclo[3.1.0]hexan-3-one

C16H26O7 (330.16784459999997)


   

(3r)-2,2-dimethyl-3-[(3s)-3-[(5s)-4-methylbicyclo[3.1.0]hex-3-en-1-yl]butyl]oxirane

(3r)-2,2-dimethyl-3-[(3s)-3-[(5s)-4-methylbicyclo[3.1.0]hex-3-en-1-yl]butyl]oxirane

C15H24O (220.18270539999997)


   

1-isopropyl-4-methylbicyclo[3.1.0]hexane-2,3,4-triol

1-isopropyl-4-methylbicyclo[3.1.0]hexane-2,3,4-triol

C10H18O3 (186.1255878)


   

1-isopropyl-4-methylbicyclo[3.1.0]hex-3-en-2-ol

1-isopropyl-4-methylbicyclo[3.1.0]hex-3-en-2-ol

C10H16O (152.12010859999998)


   

(1s,4s,5s)-4-isopropyl-1-methylbicyclo[3.1.0]hexan-2-one

(1s,4s,5s)-4-isopropyl-1-methylbicyclo[3.1.0]hexan-2-one

C10H16O (152.12010859999998)


   

1-isopropyl-4-methylbicyclo[3.1.0]hexan-2-ol

1-isopropyl-4-methylbicyclo[3.1.0]hexan-2-ol

C10H18O (154.1357578)


   

(1r,2s,5s)-1-isopropyl-4-methylbicyclo[3.1.0]hex-3-en-2-ol

(1r,2s,5s)-1-isopropyl-4-methylbicyclo[3.1.0]hex-3-en-2-ol

C10H16O (152.12010859999998)


   

1-isopropyl-4-methylbicyclo[3.1.0]hex-2-en-2-ol

1-isopropyl-4-methylbicyclo[3.1.0]hex-2-en-2-ol

C10H16O (152.12010859999998)


   

(1r,2s,3r,4s,5r)-1-isopropyl-4-methylbicyclo[3.1.0]hexane-2,3,4-triol

(1r,2s,3r,4s,5r)-1-isopropyl-4-methylbicyclo[3.1.0]hexane-2,3,4-triol

C10H18O3 (186.1255878)


   

(1s,4s)-1-isopropyl-4-methylbicyclo[3.1.0]hexan-3-one

(1s,4s)-1-isopropyl-4-methylbicyclo[3.1.0]hexan-3-one

C10H16O (152.12010859999998)


   

1-isopropyl-4-methylidenebicyclo[3.1.0]hexan-2-yl acetate

1-isopropyl-4-methylidenebicyclo[3.1.0]hexan-2-yl acetate

C12H18O2 (194.1306728)


   
   
   

(1s,5r)-5-isopropylbicyclo[3.1.0]hex-3-en-2-one

(1s,5r)-5-isopropylbicyclo[3.1.0]hex-3-en-2-one

C9H12O (136.08881019999998)


   
   

(5s)-1-isopropyl-4-methylidenebicyclo[3.1.0]hexane

(5s)-1-isopropyl-4-methylidenebicyclo[3.1.0]hexane

C10H16 (136.1251936)


   

(1r,5s)-4-(hydroxymethyl)-1-isopropylbicyclo[3.1.0]hex-3-en-2-one

(1r,5s)-4-(hydroxymethyl)-1-isopropylbicyclo[3.1.0]hex-3-en-2-one

C10H14O2 (166.09937440000002)


   

(1s,3r,5s)-1-isopropyl-4-methylidenebicyclo[3.1.0]hexan-3-yl acetate

(1s,3r,5s)-1-isopropyl-4-methylidenebicyclo[3.1.0]hexan-3-yl acetate

C12H18O2 (194.1306728)


   

(2-acetyl-1-isopropylcyclopropyl)acetic acid

(2-acetyl-1-isopropylcyclopropyl)acetic acid

C10H16O3 (184.1099386)


   

(1r,2s,3r,4r,5r)-1-isopropyl-4-methoxy-4-methylbicyclo[3.1.0]hexane-2,3-diol

(1r,2s,3r,4r,5r)-1-isopropyl-4-methoxy-4-methylbicyclo[3.1.0]hexane-2,3-diol

C11H20O3 (200.14123700000002)


   

(2r,3s,4s,5r,6r)-2-(hydroxymethyl)-6-{[(1s,3r,4r,5r)-1-isopropyl-4-methylbicyclo[3.1.0]hexan-3-yl]oxy}oxane-3,4,5-triol

(2r,3s,4s,5r,6r)-2-(hydroxymethyl)-6-{[(1s,3r,4r,5r)-1-isopropyl-4-methylbicyclo[3.1.0]hexan-3-yl]oxy}oxane-3,4,5-triol

C16H28O6 (316.1885788)


   

[(1r,2r)-2-acetyl-1-isopropylcyclopropyl]acetic acid

[(1r,2r)-2-acetyl-1-isopropylcyclopropyl]acetic acid

C10H16O3 (184.1099386)


   

4-methyl-1-(1-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}propan-2-yl)bicyclo[3.1.0]hexan-3-one

4-methyl-1-(1-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}propan-2-yl)bicyclo[3.1.0]hexan-3-one

C16H26O7 (330.16784459999997)


   

1-isopropyl-4-methylbicyclo[3.1.0]hexan-2-yl acetate

1-isopropyl-4-methylbicyclo[3.1.0]hexan-2-yl acetate

C12H20O2 (196.14632200000003)


   

(-)-α-thujene

(-)-α-thujene

C10H16 (136.1251936)


   

5-isopropyl-2-methylbicyclo[3.1.0]hexane-2,3-diol

5-isopropyl-2-methylbicyclo[3.1.0]hexane-2,3-diol

C10H18O2 (170.1306728)


   

(1s,5r)-5-isopropyl-2-methylbicyclo[3.1.0]hex-3-en-2-ol

(1s,5r)-5-isopropyl-2-methylbicyclo[3.1.0]hex-3-en-2-ol

C10H16O (152.12010859999998)


   

(1s,2s,3r,5s)-5-isopropyl-2-methylbicyclo[3.1.0]hexane-2,3-diol

(1s,2s,3r,5s)-5-isopropyl-2-methylbicyclo[3.1.0]hexane-2,3-diol

C10H18O2 (170.1306728)


   

(3s)-1-isopropyl-4-methylbicyclo[3.1.0]hexan-3-ol

(3s)-1-isopropyl-4-methylbicyclo[3.1.0]hexan-3-ol

C10H18O (154.1357578)


   

2-(hydroxymethyl)-5-isopropylbicyclo[3.1.0]hexan-2-ol

2-(hydroxymethyl)-5-isopropylbicyclo[3.1.0]hexan-2-ol

C10H18O2 (170.1306728)


   

2-(hydroxymethyl)-6-({1-isopropyl-4-methylbicyclo[3.1.0]hexan-3-yl}oxy)oxane-3,4,5-triol

2-(hydroxymethyl)-6-({1-isopropyl-4-methylbicyclo[3.1.0]hexan-3-yl}oxy)oxane-3,4,5-triol

C16H28O6 (316.1885788)


   
   

5-isopropylbicyclo[3.1.0]hex-3-en-2-one

5-isopropylbicyclo[3.1.0]hex-3-en-2-one

C9H12O (136.08881019999998)