Classification Term: 170431
Picrotoxane sesquiterpenoids (ontology term: 7e71a51900e15922d32057085dec1a4e)
found 173 associated metabolites at sub_class
metabolite taxonomy ontology rank level.
Ancestor: Pseudoalkaloids (transamidation)
Child Taxonomies: There is no child term of current ontology term.
Dendrobine
Dendrobine is a member of indoles. Dendroban-12-one is a natural product found in Dendrobium chrysanthum, Dendrobium linawianum, and Dendrobium nobile with data available. Dendrobine is an alkaloid isolated from Dendrobium nobile. Dendrobine possesses antiviral activity against influenza A viruses, with IC50s of 3.39 μM, 2.16 μM and 5.32 μM for A/FM-1/1/47 (H1N1), A/Puerto Rico/8/34 H274Y (H1N1) and A/Aichi/2/68 (H3N2), respectively[1]. Dendrobine is an alkaloid isolated from Dendrobium nobile. Dendrobine possesses antiviral activity against influenza A viruses, with IC50s of 3.39 μM, 2.16 μM and 5.32 μM for A/FM-1/1/47 (H1N1), A/Puerto Rico/8/34 H274Y (H1N1) and A/Aichi/2/68 (H3N2), respectively[1].
Ginkgolide C
Ginkgolide C is found in fats and oils. Ginkgolide C is a bitter principle from Ginkgo biloba (ginkgo). Bitter principle from Ginkgo biloba (ginkgo). Ginkgolide C is found in ginkgo nuts and fats and oils. Ginkgolide C is a flavone isolated from Ginkgo biloba leaves, possessing multiple biological functions, such as decreasing platelet aggregation and ameliorating Alzheimer disease. Ginkgolide C is a flavone isolated from Ginkgo biloba leaves, possessing multiple biological functions, such as decreasing platelet aggregation and ameliorating Alzheimer disease. Ginkgolide C is a flavone isolated from Ginkgo biloba leaves, possessing multiple biological functions, such as decreasing platelet aggregation and ameliorating Alzheimer disease. Ginkgolide C is a flavone isolated from Ginkgo biloba leaves, possessing multiple biological functions, such as decreasing platelet aggregation and ameliorating Alzheimer disease.
Ginkgolide J
Isolated from Ginkgo biloba (ginkgo). Ginkgolide J is found in ginkgo nuts and fats and oils. Ginkgolide J is found in fats and oils. Ginkgolide J is isolated from Ginkgo biloba (ginkgo Ginkgolide J is a main constituent of the non-flavone fraction of Ginkgo biloba with an IC50 range of 12-54 μM, has neuroprotective and anti neuronal apoptotic ability[1][2]. Ginkgolide J is a main constituent of the non-flavone fraction of Ginkgo biloba with an IC50 range of 12-54 μM, has neuroprotective and anti neuronal apoptotic ability[1][2].
Ginkgolide M
Ginkgolide M is found in fats and oils. Ginkgolide M is isolated from Ginkgo biloba (ginkgo Isolated from Ginkgo biloba (ginkgo). Ginkgolide M is found in fats and oils.
Sapidolide A
Sapidolide A is found in fruits. Sapidolide A is a constituent of Baccaurea sapida (Burmese grape). Constituent of Baccaurea sapida (Burmese grape). Sapidolide A is found in fruits.
Ginkgolide J
ginkgolide-J is a natural product found in Ginkgo biloba with data available. See also: Ginkgo (part of). Ginkgolide J is a main constituent of the non-flavone fraction of Ginkgo biloba with an IC50 range of 12-54 μM, has neuroprotective and anti neuronal apoptotic ability[1][2]. Ginkgolide J is a main constituent of the non-flavone fraction of Ginkgo biloba with an IC50 range of 12-54 μM, has neuroprotective and anti neuronal apoptotic ability[1][2].
Picrotoxin
Cocculus appears as a poisonous berry, the dried fruit of Anamirta cocculus L. Contains several substances including about one percent picrotoxin. Pure picrotoxin occurs as shiny leaflets with an intensely bitter taste or as a microcrystalline powder. Very poisonous!. Used in medicine as a central nervous system stimulant and antidote for barbiturate poisoning. Not currently regarded as a useful therapeutic agent. A mixture of PICROTOXININ and PICROTIN that is a noncompetitive antagonist at GABA-A receptors acting as a convulsant. Picrotoxin blocks the GAMMA-AMINOBUTYRIC ACID-activated chloride ionophore. Although it is most often used as a research tool, it has been used as a CNS stimulant and an antidote in poisoning by CNS depressants, especially the barbiturates. D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants > D003292 - Convulsants D018377 - Neurotransmitter Agents > D018682 - GABA Agents > D018756 - GABA Antagonists D020011 - Protective Agents > D000931 - Antidotes