Classification Term: 170217
有机氟类 (ontology term: 825724c43e3bd5a0cb2f401f0dc18d44)
found 8 associated metabolites at no_class-level_20 metabolite taxonomy ontology rank level.
Ancestor: 外源
Child Taxonomies: There is no child term of current ontology term.
Perfluorooctanesulfonate (PFOS)
Perfluorooctane-1-sulfonic acid is a perfluoroalkanesulfonic acid that is octane-1-sulfonic acid in which all seventeen of the hydrogens that are attached to carbons hvae been replaced by fluorines. It has a role as an antilipemic drug and a persistent organic pollutant. It is functionally related to an octane-1-sulfonic acid. Perfluorooctane sulfonate (PFOS) can cause cancer according to an independent committee of scientific and health experts. It can cause developmental toxicity according to The Environmental Protection Agency (EPA). Perfluorooctanesulfonic acid or perfluorooctane sulfonate (PFOS), is a man-made fluorosurfactant and global pollutant. PFOS was the key ingredient in Scotchgard, a fabric protector made by 3M, and numerous stain repellents. It was added to Annex B of the Stockholm Convention on Persistent Organic Pollutants in May 2009. PFOS can form from the degradation of precursors in addition to industrial production. The PFOS levels that have been detected in wildlife are considered high enough to affect health parameters, and recently higher serum levels of PFOS were found to be associated with increased risk of chronic kidney disease in the general US population, consistent with earlier animal studies. This association was independent of confounders such as age, sex, race/ethnicity, body mass index, diabetes, hypertension, and serum cholesterol level.
Perfluorododecanoic acid
Perfluorododecanoic acid, also known as tricosafluorododecanoic acid, is an organic compound containing a perfluorinated carbon chain. This compound is a type of fluoroalkanoic acid, specifically a derivative of dodecanoic acid where all the hydrogen atoms attached to the carbon atoms are replaced by fluorine atoms. A fluoroalkanoic acid that is dodecanoic acid in which all of the hydrogens attached to carbon atoms are replaced by fluorines. It is a highly persistent, bioaccumulative breakdown product of stain- and grease-proof coatings on food packaging, soft furnishings and carpets. Chemical Properties Chemical Formula: C12HF23O2 Molecular Weight: Approximately 614.1 g/mol CAS Registry Number: 307-55-1 ChEBI ID: CHEBI:90633 Appearance: It is a white powder or chunks. Physical State: At room temperature, it is a colorless liquid with a distinctive odor. Chemical Stability: The molecular structure of perfluorododecanoic acid is stable, making it chemically inert under normal conditions. It does not easily undergo chemical reactions at room temperature. Melting Point: Ranges from 105 to 108°C. Boiling Point: Approximately 245°C at 740 mmHg. Density: Estimated to be around 1.7633 g/cm³. Solubility: It is slightly soluble in chloroform (when heated) and methanol. Environmental and Health Implications Perfluorododecanoic acid is known for its persistence and bioaccumulative nature. It is a breakdown product of stain- and grease-proof coatings found on food packaging, soft furnishings, and carpets. This characteristic makes it an environmental contaminant of concern. Safety Precautions Hazardous Material: It is classified as a corrosive and irritating substance, posing risks to the eyes, respiratory system, and skin. Handling Precautions: Recommended safety measures include wearing appropriate protective clothing and immediately washing the eyes with plenty of water in case of contact, followed by medical consultation. Storage: It should be stored in a refrigerator to maintain stability. Perfluorododecanoic acid is a chemically stable and environmentally persistent compound, primarily used in industrial applications for its grease and stain-resistant properties. However, its persistence and bioaccumulative nature raise concerns about its environmental impact and potential health hazards. Perfluorododecanoic acid. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=307-55-1 (retrieved 2024-10-28) (CAS RN: 307-55-1). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Perfluoroheptanoic acid
CONFIDENCE standard compound; INTERNAL_ID 5947 CONFIDENCE standard compound; INTERNAL_ID 2410 CONFIDENCE standard compound; EAWAG_UCHEM_ID 2716
Perfluorotetradecanoic acid
CONFIDENCE standard compound; INTERNAL_ID 5954 CONFIDENCE standard compound; INTERNAL_ID 2409
Perfluorotridecanoic acid
CONFIDENCE standard compound; INTERNAL_ID 5953
Perfluorooctanesulfonic acid
Perfluorooctanesulfonic acid or perfluorooctane sulfonate (PFOS), is a man-made fluorosurfactant and global pollutant. PFOS was the key ingredient in Scotchgard, a fabric protector made by 3M, and numerous stain repellents. It was added to Annex B of the Stockholm Convention on Persistent Organic Pollutants in May 2009. PFOS can form from the degradation of precursors in addition to industrial production. The PFOS levels that have been detected in wildlife are considered high enough to affect health parameters, and recently higher serum levels of PFOS were found to be associated with increased risk of chronic kidney disease in the general US population, consistent with earlier animal studies. This association was independent of confounders such as age, sex, race/ethnicity, body mass index, diabetes, hypertension, and serum cholesterol level. Perfluorooctanesulfonic acid. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=1763-23-1 (retrieved 2024-09-27) (CAS RN: 1763-23-1). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).