Classification Term: 169520

Acridines (ontology term: 64e8f25a51f5a64b5216959231c04e76)

found 4 associated metabolites at sub_class metabolite taxonomy ontology rank level.

Ancestor: Benzoquinolines

Child Taxonomies: There is no child term of current ontology term.

Acridine

2,3,5,6-Dibenzopyridine

C13H9N (179.07349539999998)


C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent CONFIDENCE standard compound; INTERNAL_ID 2517 CONFIDENCE standard compound; INTERNAL_ID 3

   

amsacrine

amsacrine

C21H19N3O3S (393.11470640000005)


C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D007364 - Intercalating Agents L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents D000970 - Antineoplastic Agents

   

Amsacrine

N-{4-[(acridin-9-yl)amino]-3-methoxyphenyl}methanesulfonamide

C21H19N3O3S (393.11470640000005)


Aminoacridine derivative that is a potent intercalating antineoplastic agent. It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors. It is frequently used in combination with other antineoplastic agents in chemotherapy protocols. It produces consistent but acceptable myelosuppression and cardiotoxic effects. [PubChem] C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D007364 - Intercalating Agents L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents D000970 - Antineoplastic Agents

   

ACRIDINE

ACRIDINE

C13H9N (179.07349539999998)


C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent