Classification Term: 169026

HODE (ontology term: 6767af36dff885bc224040d76dd4d1eb)

found 22 associated metabolites at sub_class metabolite taxonomy ontology rank level.

Ancestor: Octadecanoids

Child Taxonomies: There is no child term of current ontology term.

Ricinoleic acid

(Z,12R)-12-hydroxyoctadec-9-enoic acid

C18H34O3 (298.2508)


Ricinoleic acid is found in corn. Ricinoleic acid occurs in castor oil and other oils e.g. grape and ergot (Claviceps purpurea) Ricinoleic acid (12-hydroxy-9-cis-octadecenoic acid) is an unsaturated omega-9 fatty acid that naturally occurs in mature Castor plant (Ricinus communis L., Euphorbiaceae) seeds or in sclerotium of ergot (Claviceps purpurea Tul., Clavicipitaceae). About 90\\% of the fatty acid content in castor oil is the triglyceride formed from ricinoleic acid. Ricinoleic acid is manufactured for industries by saponification or fractional distillation of hydrolyzed castor oil. The zinc salt is used in personal care products, such as deodorants Ricinoleic acid is a (9Z)-12-hydroxyoctadec-9-enoic acid in which the 12-hydroxy group has R-configuration.. It is a conjugate acid of a ricinoleate. Ricinoleic acid is a natural product found in Cephalocroton cordofanus, Crotalaria retusa, and other organisms with data available. See also: Polyglyceryl-6 polyricinoleate (monomer of); Polyglyceryl-4 polyricinoleate (monomer of); Polyglyceryl-5 polyricinoleate (monomer of) ... View More ... CONFIDENCE standard compound; INTERNAL_ID 219; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5632; ORIGINAL_PRECURSOR_SCAN_NO 5630 CONFIDENCE standard compound; INTERNAL_ID 219; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5657; ORIGINAL_PRECURSOR_SCAN_NO 5655 CONFIDENCE standard compound; INTERNAL_ID 219; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5730; ORIGINAL_PRECURSOR_SCAN_NO 5728 CONFIDENCE standard compound; INTERNAL_ID 219; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5665; ORIGINAL_PRECURSOR_SCAN_NO 5664 CONFIDENCE standard compound; INTERNAL_ID 219; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5630; ORIGINAL_PRECURSOR_SCAN_NO 5629 CONFIDENCE standard compound; INTERNAL_ID 219; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5665; ORIGINAL_PRECURSOR_SCAN_NO 5662 Occurs in castor oil and other oils e.g. grape and ergot (Claviceps purpurea)

   

13-HODE + 9-HODE

13-Hydroxy-9,11-octadecadienoic acid, (S)-(e,Z)-isomer

C18H32O3 (296.2351)


13-Hydroxyoctadecadienoic acid (13-HODE) (CAS: 18104-45-5), also known as 13(S)-hydroxy-9Z,11E-octadecadienoic acid or 13(S)-HODE, is the major lipoxygenation product synthesized in the body from linoleic acid. 13-HODE prevents cell adhesion to endothelial cells and can inhibit cancer metastasis. 13-HODE synthesis is enhanced by cyclic AMP. gamma-Linolenic acid, a desaturated metabolite of linoleic acid, causes substantial stimulation of 13-HODE synthesis. A fall in gamma-linolenic acid synthesis with age may be related to the age-related fall in 13-HODE formation (PMID: 9561154). 13-HODE is considered an intermediate in linoleic acid metabolism. It is generated from 13(S)-HPODE via the enzyme lipoxygenase (EC 1.13.11.12). 13-HODE has been shown to be involved in cell proliferation and differentiation in a number of systems. 13-HODE is found to be produced by prostate tumours and cell lines and researchers believe that there is a link between linoleic acid metabolism and the development or progression of prostate cancer (PMID: 9367845).

   

8S-HODE

(9Z,12Z)-(8S)-Hydroxyoctadeca-9,12-dienoic acid

C18H32O3 (296.2351)


   

Avenoleic acid

(9Z,12Z)-15-hydroxyoctadeca-9,12-dienoic acid

C18H32O3 (296.2351)


Avenoleic acid is found in cereals and cereal products. Avenoleic acid is a constituent of oat seeds (Avena sativa) Constituent of oat seeds (Avena sativa). Avenoleic acid is found in oat and cereals and cereal products.

   

13-HODE

13S-hydroxyoctadecadienoic acid

C18H32O3 (296.2351)


A HODE that consists of 9Z,11E-octadecadienoic acid carrying a 13-hydroxy substituent.

   

9-HODE

9-hydroxy-trans-10,cis-12-octadecadienoic acid

C18H32O3 (296.2351)


A HODE that consists of (10E,12Z)-octadecadienoic acid with the hydroxy substituent located at position 9. CONFIDENCE standard compound; NATIVE_RUN_ID STD_neg_MSMS_1min0132.mzML; PROCESSING averaging of repeated ion fragments at 30.0 eV within 5 ppm window [MS, MS:1000575, mean of spectra, ] CONFIDENCE standard compound; NATIVE_RUN_ID STD_neg_MSMS_1min0132.mzML; PROCESSING averaging of repeated ion fragments at 20.0 eV within 5 ppm window [MS, MS:1000575, mean of spectra, ] NATIVE_RUN_ID STD_neg_MSMS_1min0132.mzML; PROCESSING averaging of repeated ion fragments at 20.0 eV within 5 ppm window [MS, MS:1000575, mean of spectra, ]; CONFIDENCE standard compound CONFIDENCE standard compound; NATIVE_RUN_ID STD_neg_MSMS_1min0132.mzML; PROCESSING averaging of repeated ion fragments at 10.0 eV within 5 ppm window [MS, MS:1000575, mean of spectra, ] CONFIDENCE standard compound; NATIVE_RUN_ID QExHF03_NM_0001339.mzML; PROCESSING averaging of repeated ion fragments at 30.0 eV within 5 ppm window [MS, MS:1000575, mean of spectra, ] CONFIDENCE standard compound; NATIVE_RUN_ID QExHF03_NM_0001339.mzML; PROCESSING averaging of repeated ion fragments at 20.0 eV within 5 ppm window [MS, MS:1000575, mean of spectra, ] CONFIDENCE standard compound; NATIVE_RUN_ID QExHF03_NM_0001339.mzML; PROCESSING averaging of repeated ion fragments at 10.0 eV within 5 ppm window [MS, MS:1000575, mean of spectra, ] CONFIDENCE standard compound; NATIVE_RUN_ID QExHF03_NM_0001339.mzML; PROCESSING averaging of repeated ion fragments at 40.0 NCE within 5 ppm window [MS, MS:1000575, mean of spectra, ] CONFIDENCE standard compound; NATIVE_RUN_ID QExHF03_NM_0001339.mzML; PROCESSING averaging of repeated ion fragments at 30.0 NCE within 5 ppm window [MS, MS:1000575, mean of spectra, ] CONFIDENCE standard compound; NATIVE_RUN_ID QExHF03_NM_0001339.mzML; PROCESSING averaging of repeated ion fragments at 20.0 NCE within 5 ppm window [MS, MS:1000575, mean of spectra, ]

   

ricinelaidic acid

9-Octadecenoic acid, 12-hydroxy-, [R-(E)]-

C18H34O3 (298.2508)


A straight-chain, 18:1, long-chain fatty acid having a trans- double bond at position 9 and an R-oriented hydroxy group at position 12.

   

Dimorphecolic acid

9-hydroxy-trans-10,trans-12-octadecadienoic acid

C18H32O3 (296.2351)


   

Densipolic acid

12-hydroxy-cis-9,cis-15-octadecadienoic acid

C18H32O3 (296.2351)


   

alpha-artemisic acid

13-hydroxy-trans-9,trans-11-octadecadienoic acid

C18H32O3 (296.2351)


   

Avenoleic acid

15R-hydroxy-9Z,12Z-octadecadienoic acid

C18H32O3 (296.2351)


   

Isoricinoleic Acid

12-Octadecenoic acid, 9-hydroxy-, (Z)-(1)-

C18H34O3 (298.2508)


   

6-HODE

6-hydroxy-9Z,12Z-octadecadienoic acid

C18H32O3 (296.2351)


   

12R-HODE

9,15-Octadecadienoic acid, 12-hydroxy-, [R-(Z,Z)]-

C18H32O3 (296.2351)


   

13R-HODE

9,11-Octadecadienoic acid, 13-hydroxy-, [R-(E,Z)]-

C18H32O3 (296.2351)


   

10R-HODE

10R-hydroxy-8E,12Z-octadecadienoic acid

C18H32O3 (296.2351)


   

10S-HODE

10S-hydroxy-8E,12Z-octadecadienoic acid

C18H32O3 (296.2351)


   

8R-HODE

8R-hydroxy-9Z,12Z-octadecadienoic acid

C18H32O3 (296.2351)


   

9R-HODE

9R-hydroxy-10E,12Z-octadecadienoic acid

C18H32O3 (296.2351)


   

Coriolic acid

13-hydroxy-cis-9,trans-11-octadecadienoic acid

C18H32O3 (296.2351)


   

Ricinoleic acid

(9E)-12-hydroxyoctadec-9-enoic acid

C18H34O3 (298.2508)


A hydroxy fatty acid that is (9E)-octadec-9-enoic (elaidic) acid carrying a hydroxy substituent at position 12.