Classification Term: 168804
Indolines (ontology term: 9c0be834c839fc285fd633b400377bd2)
found 14 associated metabolites at sub_class metabolite taxonomy ontology rank level.
Ancestor: Tryptophan alkaloids
Child Taxonomies: There is no child term of current ontology term.
3-Methyldioxyindole
3-Methyldioxyindole is a metabolite of aldehyde dehydrogenase (NAD+) (K00128)(EC 1.2.1.3) formed during 3-methylindole metabolism (PMID: 88251990). It is the major urinary metabolite of 3-methylindole. (PMID: 2519781). It is thought that 3-Methyldioxyindole is an in vivo oxidation product of 3-methylindole which is a metabolic product of tryptophan, produced by bacteria in the colon (PMID: 2796599). 3-Methyldioxyindole is a metabolite of aldehyde dehydrogenase (NAD+) (K00128)(EC 1.2.1.3) formed during 3-methylindole metabolism (PMID: 88251990). It is the major urinary metabolite of 3-methylindole. (PMID: 2519781).
Indoline
indoline, also known as dihydroindole, belongs to the class of organic compounds known as indolines. Indolines are compounds containing an indole moiety, which consists of pyrrolidine ring fused to benzene to form 2,3-dihydroindole. Indoline is an aromatic heterocyclic organic compound with the chemical formula C8H9N. The compound is based on the indole structure, but the 2-3 bond is saturated. indoline is a strong basic compound (based on its pKa). By oxidation/dehydrogenation it can be converted to indoles. It has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing ring. Indoline was used to make Indocaine. This compound has been identified in human blood as reported by (PMID: 31557052 ). Indoline is not a naturally occurring metabolite and is only found in those individuals exposed to this compound or its derivatives. Technically Indoline is part of the human exposome. The exposome can be defined as the collection of all the exposures of an individual in a lifetime and how those exposures relate to health. An individual's exposure begins before birth and includes insults from environmental and occupational sources.