Classification Term: 1321
Glycerophosphoinositols (ontology term: CHEMONTID:0002219)
Lipids containing a glycerol moiety carrying a phosphoinositol at the 3-position." []
found 1 associated metabolites at sub_class metabolite taxonomy ontology rank level.
Ancestor: Glycerophospholipids
Child Taxonomies: Phosphatidylinositols, Lysophosphatidylinositols, 1-alkyl,2-acylglycerophosphoinositols, 1-(1Z-alkenyl),2-acylglycerophosphoinositols, Dialkylglycerophosphoinositols, Monoalkylglycerophosphoinositols, 1-(1Z-alkenyl)glycerophosphoinositols
Glycerophosphoinositol
Glycerophosphoinositol (CAS: 16824-65-0), also known as 1-(sn-glycero-3-phospho)-1D-myo-inositol, is produced through deacylation by phospholipase B of the essential phospholipid phosphatidylinositol. Glycerophosphoinositols are ubiquitous phosphoinositide metabolites involved in the control of several cell functions. They exert their actions both intracellularly and by rapidly equilibrating across the plasma membrane. Their transport is mediated by the Glut2 transporter, the human ortholog of GIT1 (PMID: 17141226). Glycerophosphoinositol is a substrate for glycerophosphoinositol inositolphosphodiesterase (EC 3.1.4.43) and is involved in the following reaction: 1-(sn-glycero-3-phospho)-1D-myo-inositol + H2O = glycerol + 1D-myo-inositol 1-phosphate. It is also a substrate for glycerophosphoinositol glycerophosphodiesterase (EC 3.1.4.44) which catalyzes the chemical reaction: 1-(sn-glycero-3-phospho)-1D-myo-inositol + H2O = myo-inositol + sn-glycerol 3-phosphate. Isolated from beef liver. Glycerylphosphoinositol is found in animal foods.