sodium glycocholate (BioDeep_00000829749)
PANOMIX_OTCML-2023 Bile acids Antitumor activity
代谢物信息卡片
sodium glycocholate
化学式: C26H42NNaO6 (487.29096720000007)
中文名称: 甘氨胆酸钠
谱图信息:
最多检出来源 Homo sapiens(bile_acids) 9.77%
Reviewed
Last reviewed on 2024-08-07.
Cite this Page
sodium glycocholate. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China.
https://query.biodeep.cn/s/sodium_glycocholate (retrieved
2024-11-10) (BioDeep RN: BioDeep_00000829749). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
分子结构信息
SMILES: CC(CCC(=O)NCC(=O)[O-])C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C.[Na+]
InChI: /q
描述信息
D005765 - Gastrointestinal Agents > D002756 - Cholagogues and Choleretics
D005765 - Gastrointestinal Agents > D001647 - Bile Acids and Salts
D005765 - Gastrointestinal Agents > D002793 - Cholic Acids
D013501 - Surface-Active Agents > D003902 - Detergents
Glycocholic acid sodium is an orally active bile acid with anticancer activity, targeting against pump resistance-related and non-pump resistance-related pathways[1].
Glycocholic acid sodium is an orally active bile acid with anticancer activity, targeting against pump resistance-related and non-pump resistance-related pathways[1].
同义名列表
2 个代谢物同义名
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:36273
- PubChem: 23670522
- MeSH: Glycocholic Acid
- CAS: 863-57-0
- medchemexpress: HY-N1423A
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Hamid Alghurabi, Huda Jassim Muhammad, Tatsuaki Tagami, Koki Ogawa, Tetsuya Ozeki. Optimization, cellular uptake, and in vivo evaluation of Eudragit S100-coated bile salt-containing liposomes for oral colonic delivery of 5-aminosalicylic acid.
International journal of pharmaceutics.
2023 Dec; 648(?):123597. doi:
10.1016/j.ijpharm.2023.123597. [PMID: 37952559] - Yu Tang, Zhu Han, Han Zhang, Li Che, Genjie Liao, Jun Peng, Yu Lin, Yi Wang. Characterization of Calculus bovis by principal component analysis assisted qHNMR profiling to distinguish nefarious frauds.
Journal of pharmaceutical and biomedical analysis.
2023 Mar; 228(?):115320. doi:
10.1016/j.jpba.2023.115320. [PMID: 36871364] - Shibin Yao, Shengjie Ren, Chunfang Cai, Xiamin Cao, Ye Shi, Ping Wu, Yuantu Ye. Glycocholic acid supplementation improved growth performance and alleviated tissue damage in the liver and intestine in Pelteobagrus fulvidraco fed a high-pectin diet.
Fish physiology and biochemistry.
2022 Dec; ?(?):. doi:
10.1007/s10695-022-01148-3. [PMID: 36454392] - Xiaolu Zhou, Yaling Li, Ren Mu, Chuanming Wang, Yuyan Song, Caibi Zhou, Xin Mei. Duyun compound green tea extracts regulate bile acid metabolism on mice induced by high-fat diet.
The British journal of nutrition.
2022 Oct; ?(?):1-9. doi:
10.1017/s0007114522003166. [PMID: 36210537] - Jian Wu, Yanping Xu, Yubao Cui, Mariza Bortolanza, Minjie Wang, Bin Jiang, Meina Yan, Wei Liang, Yiwen Yao, Qiaoling Pan, Jinfeng Yang, Jiong Yu, Dawei Wang, Hongcui Cao, Lanjuan Li. Dynamic changes of serum metabolites associated with infection and severity of patients with acute hepatitis E infection.
Journal of medical virology.
2022 06; 94(6):2714-2726. doi:
10.1002/jmv.27669. [PMID: 35199373] - Feiyang Deng, You Han Bae. Lipid raft-mediated and upregulated coordination pathways assist transport of glycocholic acid-modified nanoparticle in a human breast cancer cell line of SK-BR-3.
International journal of pharmaceutics.
2022 Apr; 617(?):121589. doi:
10.1016/j.ijpharm.2022.121589. [PMID: 35176336] - Hongxue Liu, Haidong Wang, Muling Zhang. Deep Learning Algorithm-Based Magnetic Resonance Imaging Feature-Guided Serum Bile Acid Profile and Perinatal Outcomes in Intrahepatic Cholestasis of Pregnancy.
Computational and mathematical methods in medicine.
2022; 2022(?):8081673. doi:
10.1155/2022/8081673. [PMID: 35707042] - Michelle L Manni, Victoria A Heinrich, Gregory J Buchan, James P O'Brien, Crystal Uvalle, Veronika Cechova, Adolf Koudelka, Dharti Ukani, Mohamad Rawas-Qalaji, Tim D Oury, Renee Hart, Madeline Ellgass, Steven J Mullett, Merritt L Fajt, Sally E Wenzel, Fernando Holguin, Bruce A Freeman, Stacy G Wendell. Nitroalkene fatty acids modulate bile acid metabolism and lung function in obese asthma.
Scientific reports.
2021 09; 11(1):17788. doi:
10.1038/s41598-021-96471-9. [PMID: 34493738] - Xiping Cui, Qiyi He, Huiyi Yang, Yingshan Chen, Ding Shen, Sergei A Eremin, Yunping Mu, Suqing Zhao. Development of enzyme-free single-step immunoassays for glycocholic acid based on palladium nanoparticle-mediated signal generation.
Analytical and bioanalytical chemistry.
2021 Sep; 413(23):5733-5742. doi:
10.1007/s00216-021-03548-5. [PMID: 34476526] - Ying Han, Wei Liu, Liqing Chen, Xin Xin, Qiming Wang, Xintong Zhang, Mingji Jin, Zhonggao Gao, Wei Huang. Effective oral delivery of Exenatide-Zn2+ complex through distal ileum-targeted double layers nanocarriers modified with deoxycholic acid and glycocholic acid in diabetes therapy.
Biomaterials.
2021 08; 275(?):120944. doi:
10.1016/j.biomaterials.2021.120944. [PMID: 34153783] - Hui Li, Yan Wang, Shizhao Ma, Chaoqun Zhang, Hua Liu, Dianxing Sun. Clinical significance of small molecule metabolites in the blood of patients with different types of liver injury.
Scientific reports.
2021 06; 11(1):11642. doi:
10.1038/s41598-021-91164-9. [PMID: 34079030] - Rong Wang, Hongmin Jiang, Yongjun Wang, Yuanqing Yang. Serum TBA and GCA Levels Across Pregnancy and the Gestational Age-Specific Reference Intervals for Pregnant Chinese.
Clinical laboratory.
2021 Jun; 67(6):. doi:
10.7754/clin.lab.2020.201043. [PMID: 34107618] - Qiyi He, Yanxiong Fang, Huiyi Yang, Ding Shen, Yingshan Chen, Yingying Zhong, Xiangguang Li, Sergei A Eremin, Xiping Cui, Suqing Zhao. Enhanced performance of a surface plasmon resonance-based immunosensor for the detection of glycocholic acid.
Analytical methods : advancing methods and applications.
2021 04; 13(16):1919-1924. doi:
10.1039/d1ay00357g. [PMID: 33913980] - Guangzheng Zhang, Zhenyuan Lang, Qifan Yang, You Nie, Zhihan Wang, Ming Gao, Nan Zhang, Xia Xu. UPLC-Q-TOF/MS-based plasma metabolome to identify biomarkers and time of injury in traumatic brain injured rats.
Neuroreport.
2021 04; 32(6):415-422. doi:
10.1097/wnr.0000000000001576. [PMID: 33788810] - Ruirui Dong, Ningzhen Ye, Shaojie Zhao, Gaoying Wang, Yan Zhang, Tiejun Wang, Ping Zou, Jing Wang, Tingting Yao, Minjian Chen, Conghua Zhou, Ting Zhang, Liang Luo. Studies on Novel Diagnostic and Predictive Biomarkers of Intrahepatic Cholestasis of Pregnancy Through Metabolomics and Proteomics.
Frontiers in immunology.
2021; 12(?):733225. doi:
10.3389/fimmu.2021.733225. [PMID: 34721396] - Chong Fu, Yali Xu. Value of Serum Glycocholic Acid and Total Bile Acids in Predicting Maternal and Perinatal Outcomes in Intrahepatic Cholestasis of Pregnancy.
Journal of healthcare engineering.
2021; 2021(?):3911998. doi:
10.1155/2021/3911998. [PMID: 34540186] - José Tadeu Stefano, Laura Vilar Guedes, Arthur Alencar Arrais de Souza, Denise Siqueira Vanni, Venâncio Avancini Ferreira Alves, Flair José Carrilho, Alvaro Largura, Marco Arrese, Claudia P Oliveira. Usefulness of collagen type IV in the detection of significant liver fibrosis in nonalcoholic fatty liver disease.
Annals of hepatology.
2021 Jan; 20(?):100253. doi:
10.1016/j.aohep.2020.08.070. [PMID: 32949785] - Qiyi He, Huiyi Yang, Yingshan Chen, Ding Shen, Xiping Cui, Chunguo Zhang, Huanxin Xiao, Sergei A Eremin, Yanxiong Fang, Suqing Zhao. Prussian blue nanoparticles with peroxidase-mimicking properties in a dual immunoassays for glycocholic acid.
Journal of pharmaceutical and biomedical analysis.
2020 Aug; 187(?):113317. doi:
10.1016/j.jpba.2020.113317. [PMID: 32416340] - Jiayao Liu, Wenjuan Xu, Anna Zhu, Haoxiang Kang, Yu Cao, Feng Long. Reusable optofluidic point-of-care testing platform with lyophilized specific antibody for fluorescence detection of cholylglycine in serum.
Mikrochimica acta.
2020 07; 187(8):439. doi:
10.1007/s00604-020-04424-2. [PMID: 32653962] - Weiguo Sui, Qing Gan, Fuhua Liu, Minglin Ou, Bingguo Wang, Songbai Liao, Liusheng Lai, Huaizhou Chen, Ming Yang, Yong Dai. Dynamic Metabolomics Study of the Bile Acid Pathway During Perioperative Primary Hepatic Carcinoma Following Liver Transplantation.
Annals of transplantation.
2020 Jun; 25(?):e921844. doi:
10.12659/aot.921844. [PMID: 32572018] - Erikka Loftfield, Joseph A Rothwell, Rashmi Sinha, Pekka Keski-Rahkonen, Nivonirina Robinot, Demetrius Albanes, Stephanie J Weinstein, Andriy Derkach, Joshua Sampson, Augustin Scalbert, Neal D Freedman. Prospective Investigation of Serum Metabolites, Coffee Drinking, Liver Cancer Incidence, and Liver Disease Mortality.
Journal of the National Cancer Institute.
2020 03; 112(3):286-294. doi:
10.1093/jnci/djz122. [PMID: 31168595] - Kyoung Sub Kim, Yu Seok Youn, You Han Bae. Immune-triggered cancer treatment by intestinal lymphatic delivery of docetaxel-loaded nanoparticle.
Journal of controlled release : official journal of the Controlled Release Society.
2019 10; 311-312(?):85-95. doi:
10.1016/j.jconrel.2019.08.027. [PMID: 31461664] - Patricia Mitry, Nina Wawro, Sapna Sharma, Jennifer Kriebel, Anna Artati, Jerzy Adamski, Margit Heier, Christa Meisinger, Barbara Thorand, Harald Grallert, Annette Peters, Jakob Linseisen. Associations between usual food intake and faecal sterols and bile acids: results from the Cooperative Health Research in the Augsburg Region (KORA FF4) study.
The British journal of nutrition.
2019 08; 122(3):309-321. doi:
10.1017/s000711451900103x. [PMID: 31182174] - Issey Takehara, Nobuaki Watanabe, Daiki Mori, Osamu Ando, Hiroyuki Kusuhara. Effect of Rifampicin on the Plasma Concentrations of Bile Acid-O-Sulfates in Monkeys and Human Liver-Transplanted Chimeric Mice With or Without Bile Flow Diversion.
Journal of pharmaceutical sciences.
2019 08; 108(8):2756-2764. doi:
10.1016/j.xphs.2019.03.021. [PMID: 30905707] - Alvaro Alonso, Bing Yu, Yan V Sun, Lin Y Chen, Laura R Loehr, Wesley T O'Neal, Elsayed Z Soliman, Eric Boerwinkle. Serum Metabolomics and Incidence of Atrial Fibrillation (from the Atherosclerosis Risk in Communities Study).
The American journal of cardiology.
2019 06; 123(12):1955-1961. doi:
10.1016/j.amjcard.2019.03.017. [PMID: 30979411] - Qiangyuan Fan, Yongtai Zhang, Xuefeng Hou, Zhe Li, Kai Zhang, Qun Shao, Nianping Feng. Improved oral bioavailability of notoginsenoside R1 with sodium glycocholate-mediated liposomes: Preparation by supercritical fluid technology and evaluation in vitro and in vivo.
International journal of pharmaceutics.
2018 Dec; 552(1-2):360-370. doi:
10.1016/j.ijpharm.2018.10.005. [PMID: 30292894] - Qiyi He, Xiping Cui, Ding Shen, Yingshan Chen, Zhengyun Jiang, Rui Lv, Sergei A Eremin, Suqing Zhao. Development of a simple, rapid and high-throughput fluorescence polarization immunoassay for glycocholic acid in human urine.
Journal of pharmaceutical and biomedical analysis.
2018 Sep; 158(?):431-437. doi:
10.1016/j.jpba.2018.06.023. [PMID: 29945060] - Xiping Cui, Natalia Vasylieva, Ding Shen, Bogdan Barnych, Jun Yang, Qiyi He, Zhengyun Jiang, Suqing Zhao, Bruce D Hammock. Biotinylated single-chain variable fragment-based enzyme-linked immunosorbent assay for glycocholic acid.
The Analyst.
2018 Apr; 143(9):2057-2065. doi:
10.1039/c7an02024d. [PMID: 29629470] - Cheng Guo, Cong Xie, Peili Ding, Guangming Qin, Weimin Mo, Xiaoji Cao, Shu Zheng. Quantification of glycocholic acid in human serum by stable isotope dilution ultra performance liquid chromatography electrospray ionization tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2018 Jan; 1072(?):315-319. doi:
10.1016/j.jchromb.2017.11.037. [PMID: 29202363] - Xiping Cui, Natalia Vasylieva, Panpan Wu, Bogdan Barnych, Jun Yang, Ding Shen, Qiyi He, Shirley J Gee, Suqing Zhao, Bruce D Hammock. Development of an Indirect Competitive Enzyme-Linked Immunosorbent Assay for Glycocholic Acid Based on Chicken Single-Chain Variable Fragment Antibodies.
Analytical chemistry.
2017 10; 89(20):11091-11097. doi:
10.1021/acs.analchem.7b03190. [PMID: 28942640] - Mariapina D'Onofrio, Carlo Giorgio Barracchia, Andrea Bortot, Francesca Munari, Serena Zanzoni, Michael Assfalg. Molecular differences between human liver fatty acid binding protein and its T94A variant in their unbound and lipid-bound states.
Biochimica et biophysica acta. Proteins and proteomics.
2017 Sep; 1865(9):1152-1159. doi:
10.1016/j.bbapap.2017.06.025. [PMID: 28668637] - Veronika Thöni, Alexandra Pfister, Andreas Melmer, Barbara Enrich, Karin Salzmann, Susanne Kaser, Claudia Lamina, Christoph F Ebenbichler, Hubert Hackl, Herbert Tilg, Alexander R Moschen. Dynamics of Bile Acid Profiles, GLP-1, and FGF19 After Laparoscopic Gastric Banding.
The Journal of clinical endocrinology and metabolism.
2017 08; 102(8):2974-2984. doi:
10.1210/jc.2017-00235. [PMID: 28591793] - Xiao-Hong Yu, Jing Sun, Yan Wang, Ya-Bin Zhou. Biomarkers of unstable angina pectoris and yangxin decoction intervention: An exploratory metabonomics study of blood plasma.
Medicine.
2017 May; 96(21):e6998. doi:
10.1097/md.0000000000006998. [PMID: 28538412] - Hui Li, Su-Fang Fan, Yan Wang, Shi-Gang Shen, Dian-Xing Sun. Rapid Detection of Small Molecule Metabolites in Serum of Hepatocellular Carcinoma Patients Using Ultrafast Liquid Chromatography-Ion Trap-Time of Flight Tandem Mass Spectrometry.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.
2017; 33(5):573-578. doi:
10.2116/analsci.33.573. [PMID: 28496060] - Quan-Fu Li, Yan-Mei Zhan, Yong-Gang Zhong, Bo Zhang, Chang-Qing Ge. Macromolecular Crowding Agents-Assisted Imprinted Polymers For Analysis Of Glycocholic Acid In Human Plasma And Urine.
Biomedical chromatography : BMC.
2016 Nov; 30(11):1706-1713. doi:
10.1002/bmc.3737. [PMID: 27061917] - Alessandra Maroni, Maria Dorly Del Curto, Stefano Salmaso, Lucia Zema, Alice Melocchi, Paolo Caliceti, Andrea Gazzaniga. In vitro and in vivo evaluation of an oral multiple-unit formulation for colonic delivery of insulin.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2016 Nov; 108(?):76-82. doi:
10.1016/j.ejpb.2016.08.002. [PMID: 27519826] - Hongmin Xu, Lei Zhang, Huan Kang, Jiandong Zhang, Jie Liu, Shuye Liu. Serum Metabonomics of Mild Acute Pancreatitis.
Journal of clinical laboratory analysis.
2016 Nov; 30(6):990-998. doi:
10.1002/jcla.21969. [PMID: 27169745] - Shyamchand Mayengbam, James D House, Michel Aliani. Investigation of vitamin B₆ inadequacy, induced by exposure to the anti-B₆ factor 1-amino D-proline, on plasma lipophilic metabolites of rats: a metabolomics approach.
European journal of nutrition.
2016 Apr; 55(3):1213-23. doi:
10.1007/s00394-015-0934-x. [PMID: 26009005] - Gergő Horváth, Ákos Bencsura, Ágnes Simon, Gregory P Tochtrop, Gregory T DeKoster, Douglas F Covey, David P Cistola, Orsolya Toke. Structural determinants of ligand binding in the ternary complex of human ileal bile acid binding protein with glycocholate and glycochenodeoxycholate obtained from solution NMR.
The FEBS journal.
2016 Feb; 283(3):541-55. doi:
10.1111/febs.13610. [PMID: 26613247] - Guixia Ling, Tianhong Zhang, Peng Zhang, Jin Sun, Zhonggui He. Synergistic and complete reversal of the multidrug resistance of mitoxantrone hydrochloride by three-in-one multifunctional lipid-sodium glycocholate nanocarriers based on simultaneous BCRP and Bcl-2 inhibition.
International journal of nanomedicine.
2016 ; 11(?):4077-91. doi:
10.2147/ijn.s95767. [PMID: 27601896] - James E Heubi, Kenneth D R Setchell, Pinky Jha, Donna Buckley, Wujuan Zhang, Philip Rosenthal, Carol Potter, Simon Horslen, David Suskind. Treatment of bile acid amidation defects with glycocholic acid.
Hepatology (Baltimore, Md.).
2015 Jan; 61(1):268-74. doi:
10.1002/hep.27401. [PMID: 25163551] - Toshihiro Kobayashi, Yuriko Matsumura, Toshihiko Ozawa, Hiroyuki Yanai, Atsuo Iwasawa, Toshiaki Kamachi, Kouichi Fujiwara, Noriaki Tanaka, Masahiro Kohno. Exploration of novel predictive markers in rat plasma of the early stages of chronic renal failure.
Analytical and bioanalytical chemistry.
2014 Feb; 406(5):1365-76. doi:
10.1007/s00216-013-7472-2. [PMID: 24232639] - Lina Luo, Shelli Schomaker, Christopher Houle, Jiri Aubrecht, Jennifer L Colangelo. Evaluation of serum bile acid profiles as biomarkers of liver injury in rodents.
Toxicological sciences : an official journal of the Society of Toxicology.
2014 Jan; 137(1):12-25. doi:
10.1093/toxsci/kft221. [PMID: 24085190] - Filippo Favretto, Michael Assfalg, Mariana Gallo, Daniel Oscar Cicero, Mariapina D'Onofrio, Henriette Molinari. Ligand binding promiscuity of human liver fatty acid binding protein: structural and dynamic insights from an interaction study with glycocholate and oleate.
Chembiochem : a European journal of chemical biology.
2013 Sep; 14(14):1807-19. doi:
10.1002/cbic.201300156. [PMID: 23757005] - Aihua Zhang, Hui Sun, Guangli Yan, Ying Han, Yuan Ye, Xijun Wang. Urinary metabolic profiling identifies a key role for glycocholic acid in human liver cancer by ultra-performance liquid-chromatography coupled with high-definition mass spectrometry.
Clinica chimica acta; international journal of clinical chemistry.
2013 Mar; 418(?):86-90. doi:
10.1016/j.cca.2012.12.024. [PMID: 23313056] - Nilanjana Das, Parshotam Madan, Senshang Lin. Statistical optimization of insulin-loaded Pluronic F-127 gels for buccal delivery of basal insulin.
Pharmaceutical development and technology.
2012 May; 17(3):363-74. doi:
10.3109/10837450.2010.542164. [PMID: 21214425] - Gergo Horváth, Péter Király, Gábor Tárkányi, Orsolya Toke. Internal motions and exchange processes in human ileal bile acid binding protein as studied by backbone (15)N nuclear magnetic resonance spectroscopy.
Biochemistry.
2012 Mar; 51(9):1848-61. doi:
10.1021/bi201588q. [PMID: 22329738] - Haiqiang Jiang, Lei Nie, Yunlun Li, Jun Xie. Application of ultra-performance liquid chromatography coupled with mass spectrometry to metabonomic study on spontaneously hypertensive rats and intervention effects of Ping Gan prescription.
Journal of separation science.
2012 Feb; 35(4):483-9. doi:
10.1002/jssc.201100769. [PMID: 22282408] - Dong-Ho Oh, Kyeung-Hwa Chun, Sang-Ok Jeon, Jeong-Won Kang, Sangkil Lee. Enhanced transbuccal salmon calcitonin (sCT) delivery: effect of chemical enhancers and electrical assistance on in vitro sCT buccal permeation.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2011 Oct; 79(2):357-63. doi:
10.1016/j.ejpb.2011.05.010. [PMID: 21683790] - Jing He, Lu Chen, Cheng Liang. [Clinical analysis of fetal death cases in intrahepatic cholestasis of pregnancy].
Zhonghua fu chan ke za zhi.
2011 May; 46(5):333-7. doi:
. [PMID: 21733367] - Jocelyn Trottier, Andrzej Białek, Patrick Caron, Robert J Straka, Piotr Milkiewicz, Olivier Barbier. Profiling circulating and urinary bile acids in patients with biliary obstruction before and after biliary stenting.
PloS one.
2011; 6(7):e22094. doi:
10.1371/journal.pone.0022094. [PMID: 21760958] - David C Turner, Fuchang Yin, James T Kindt, Hailing Zhang. Molecular dynamics simulations of glycocholate-oleic acid mixed micelle assembly.
Langmuir : the ACS journal of surfaces and colloids.
2010 Apr; 26(7):4687-92. doi:
10.1021/la903573m. [PMID: 20112949] - James R Reed. The use of liposomes in the study of drug metabolism: a method to incorporate the enzymes of the cytochrome p450 monooxygenase system into phospholipid, bilayer vesicles.
Methods in molecular biology (Clifton, N.J.).
2010; 606(?):11-20. doi:
10.1007/978-1-60761-447-0_2. [PMID: 20013386] - Akhlesh Kumar Jain, Roop K Khar, Farhan J Ahmed, Prakash V Diwan. Effective insulin delivery using starch nanoparticles as a potential trans-nasal mucoadhesive carrier.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2008 Jun; 69(2):426-35. doi:
10.1016/j.ejpb.2007.12.001. [PMID: 18295464] - Zhou Xu, Jian-Chu Ke, Ai-Yun Xing. [Study on relationship between expression of familial intrahepatic cholestasis 1 mRNA in placenta and Intrahepatic cholestasis of pregnancy].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition.
2008 May; 39(3):430-3. doi:
. [PMID: 18575333] - Mikael Gunnarsson, Sigrid Leide-Svegborn, Kristina Stenström, Göran Skog, Lars-Erik Nilsson, Ola Thorsson, Ragnar Hellborg, Sören Mattsson. Long-term biokinetics and radiation exposure of patients undergoing 14C-glycocholic acid and 14C-xylose breath tests.
Cancer biotherapy & radiopharmaceuticals.
2007 Dec; 22(6):762-71. doi:
10.1089/cbr.2007.0350. [PMID: 18158767] - K Rifai, J Ockenga, M P Manns, S C Bischoff. Repeated administration of a vitamin preparation containing glycocholic acid in patients with hepatobiliary disease.
Alimentary pharmacology & therapeutics.
2006 May; 23(9):1337-45. doi:
10.1111/j.1365-2036.2006.02895.x. [PMID: 16629939] - Dian-yun Shi, Hua Chen, Xiao-yun Tian. [Clinical and experimental study on wuling pill in treating gestation period intrahepatic cholestasis].
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
2006 Feb; 26(2):114-8. doi:
. [PMID: 16548349] - Masataka Katsuma, Shunsuke Watanabe, Hitoshi Kawai, Shigeo Takemura, Kazuhiro Sako. Effects of absorption promoters on insulin absorption through colon-targeted delivery.
International journal of pharmaceutics.
2006 Jan; 307(2):156-62. doi:
10.1016/j.ijpharm.2005.09.028. [PMID: 16289574] - Majella E Lane, Caitriona M O'driscoll, Owen I Corrigan. Quantitative estimation of the effects of bile salt surfactant systems on insulin stability and permeability in the rat intestine using a mass balance model.
The Journal of pharmacy and pharmacology.
2005 Feb; 57(2):169-75. doi:
10.1211/0022357055434. [PMID: 15720779] - Ya-Juan Zhao, Ya-Fei Yue, Xiao-Qin Liu, Shu-Hong Li, Zhao-Yang Liu, Yu Wang. [Study on relationship between serum cholylglycine and placental apoptosis in patients with intrahepatic cholestasis of pregnancy].
Zhonghua fu chan ke za zhi.
2004 Jul; 39(7):446-8. doi:
. [PMID: 15347465] - Hui Liu, Wei-san Pan, Rong Du, Xiao-dong Li, Ren Tang. [Effects of protease inhibitors on intestinal absorption of insulin].
Yao xue xue bao = Acta pharmaceutica Sinica.
2004 Feb; 39(2):140-3. doi:
NULL. [PMID: 15127624] - Neil S Cameron, Frederick G Morin, Adi Eisenberg, G Ronald Brown. Poly(N,N,N-trimethylammoniumalkyl acrylamide chloride) based hydrogels for serum cholesterol reduction.
Biomacromolecules.
2004 Jan; 5(1):24-31. doi:
10.1021/bm034174v. [PMID: 14715004] - M A Serrano, R I R Macias, M Vallejo, O Briz, A Bravo, M J Pascual, M V St-Pierre, B Stieger, P J Meier, J J G Marin. Effect of ursodeoxycholic acid on the impairment induced by maternal cholestasis in the rat placenta-maternal liver tandem excretory pathway.
The Journal of pharmacology and experimental therapeutics.
2003 May; 305(2):515-24. doi:
10.1124/jpet.102.047977. [PMID: 12606635] - Arshia Shariff, Sarasija Suresh, K L K Paranjothy, K V Nagendra Prasad. Effect of sodium glycocholate on development of tolerance to Parthenium hysterophorus extracts.
Indian journal of experimental biology.
2003 Apr; 41(4):370-2. doi:
". [PMID: 15255651] - D Carter, H C S Howlett, N F Wiernsperger, C J Bailey. Differential effects of metformin on bile salt absorption from the jejunum and ileum.
Diabetes, obesity & metabolism.
2003 Mar; 5(2):120-5. doi:
10.1046/j.1463-1326.2003.00252.x. [PMID: 12630937] - Zhe-Sheng Chen, Elizabeth Hopper-Borge, Martin G Belinsky, Irina Shchaveleva, Elena Kotova, Gary D Kruh. Characterization of the transport properties of human multidrug resistance protein 7 (MRP7, ABCC10).
Molecular pharmacology.
2003 Feb; 63(2):351-8. doi:
10.1124/mol.63.2.351. [PMID: 12527806] - J L Murphy, A V Badaloo, B Chambers, T E Forrester, S A Wootton, A A Jackson. Maldigestion and malabsorption of dietary lipid during severe childhood malnutrition.
Archives of disease in childhood.
2002 Dec; 87(6):522-5. doi:
10.1136/adc.87.6.522. [PMID: 12456554] - Norihiro Kobayashi, Hiroshi Katsumata, Yoshiaki Uto, Junichi Goto, Toshifumi Niwa, Koju Kobayashi, Yoshiaki Mizuuchi. A monoclonal antibody-based enzyme-linked immunosorbent assay of glycolithocholic acid sulfate in human urine for liver function test.
Steroids.
2002 Sep; 67(10):827-33. doi:
10.1016/s0039-128x(02)00036-3. [PMID: 12231118] - Dian-yun Shi, Hua Chen, Mei Xiao. [Observation on effect of danxiaoling in supplementary treatment of intrahepatic cholestasis in pregnancy].
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
2002 Feb; 22(2):116-8. doi:
NULL. [PMID: 12585148] - M A Bagger, H W Nielsen, E Bechgaard. Nasal bioavailability of peptide T in rabbits: absorption enhancement by sodium glycocholate and glycofurol.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2001 Aug; 14(1):69-74. doi:
10.1016/s0928-0987(01)00146-4. [PMID: 11457652] - J L Murphy, E N Robinson, T E Forrester, S A Wootton, A A Jackson. Gastrointestinal handling and metabolic disposal of 13C-labelled tripalmitin during rehabilitation from childhood malnutrition.
The British journal of nutrition.
2001 Jun; 85(6):705-13. doi:
NULL. [PMID: 11430775] - H Zeng, G Liu, P A Rea, G D Kruh. Transport of amphipathic anions by human multidrug resistance protein 3.
Cancer research.
2000 Sep; 60(17):4779-84. doi:
. [PMID: 10987286] - H Bonge, S Hallén, J Fryklund, J E Sjöström. Cytostar-T scintillating microplate assay for measurement of sodium-dependent bile acid uptake in transfected HEK-293 cells.
Analytical biochemistry.
2000 Jun; 282(1):94-101. doi:
10.1006/abio.2000.4600. [PMID: 10860504] - C Lücke, F Zhang, J A Hamilton, J C Sacchettini, H Rüterjans. Solution structure of ileal lipid binding protein in complex with glycocholate.
European journal of biochemistry.
2000 May; 267(10):2929-38. doi:
10.1046/j.1432-1327.2000.01307.x. [PMID: 10806391] - R I Macias, M J Pascual, A Bravo, M P Alcalde, M G Larena, M V St-Pierre, M A Serrano, J J Marin. Effect of maternal cholestasis on bile acid transfer across the rat placenta-maternal liver tandem.
Hepatology (Baltimore, Md.).
2000 Apr; 31(4):975-83. doi:
10.1053/he.2000.5921. [PMID: 10733555] - M J Monte, S Dominguez, M F Palomero, R I Macias, J J Marin. Further evidence of the usefulness of bile acids as molecules for shuttling cytostatic drugs toward liver tumors.
Journal of hepatology.
1999 Sep; 31(3):521-8. doi:
10.1016/s0168-8278(99)80046-4. [PMID: 10488713] - A E Sayad, R A Farah, Z R Rogers, J E Heubi, G R Buchanan, R H Squires. Correlation of serum cholylglycine level with hepatic dysfunction in children with sickle cell anemia.
Clinical pediatrics.
1999 May; 38(5):293-6. doi:
10.1177/000992289903800507. [PMID: 10349527] - R I Macias, M Y El-Mir, M J Monte, M A Serrano, M J Garcia, J J Marin. Cholephilic characteristics of a new cytostatic complex of cisplatin with glycocholate (Bamet-R2).
Journal of controlled release : official journal of the Controlled Release Society.
1999 Feb; 57(2):161-9. doi:
10.1016/s0168-3659(98)00114-x. [PMID: 9971896] - K Fadden, M J Hill, E Latymer, G Low, R W Owen. Steroid metabolism along the gastrointestinal tract of the cannulated pig.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP).
1999 Feb; 8(1):35-40. doi:
10.1097/00008469-199902000-00005. [PMID: 10091041] - H A Lemonde, A W Johnson, P T Clayton. The identification of unusual bile acid metabolites by tandem mass spectrometry: use of low-energy collision-induced dissociation to produce informative spectra.
Rapid communications in mass spectrometry : RCM.
1999; 13(12):1159-64. doi:
10.1002/(sici)1097-0231(19990630)13:12<1159::aid-rcm636>3.0.co;2-#. [PMID: 10390861] - I Serna Miquel, R Bataller Sifré, R Bataller Alberola, J L Moreno Frígols. [Hepatobiliary clearance of glycocholic acid in Gilbert's disease].
Anales de medicina interna (Madrid, Spain : 1984).
1998 Nov; 15(11):580-3. doi:
. [PMID: 9882854] - E A Trautwein, D Rieckhoff, H F Erbersdobler. Dietary inulin lowers plasma cholesterol and triacylglycerol and alters biliary bile acid profile in hamsters.
The Journal of nutrition.
1998 Nov; 128(11):1937-43. doi:
10.1093/jn/128.11.1937. [PMID: 9808646] - J J Marin, R I Macias, J J Criado, A Bueno, M J Monte, M A Serrano. DNA interaction and cytostatic activity of the new liver organotropic complex of cisplatin with glycocholic acid: Bamet-R2.
International journal of cancer.
1998 Oct; 78(3):346-52. doi:
10.1002/(sici)1097-0215(19981029)78:3<346::aid-ijc15>3.0.co;2-4. [PMID: 9766570] - S C Chia, N V Bergasa, D E Kleiner, Z Goodman, J H Hoofnagle, A M Di Bisceglie. Pruritus as a presenting symptom of chronic hepatitis C.
Digestive diseases and sciences.
1998 Oct; 43(10):2177-83. doi:
10.1023/a:1026646017851. [PMID: 9790451] - R I Macias, M J Monte, M Y El-Mir, G R Villanueva, J J Marin. Transport and biotransformation of the new cytostatic complex cis-diammineplatinum(II)-chlorocholylglycinate (Bamet-R2) by the rat liver.
Journal of lipid research.
1998 Sep; 39(9):1792-8. doi:
10.1016/s0022-2275(20)32166-0. [PMID: 9741691] - M A Serrano, D Brites, M G Larena, M J Monte, M P Bravo, N Oliveira, J J Marin. Beneficial effect of ursodeoxycholic acid on alterations induced by cholestasis of pregnancy in bile acid transport across the human placenta.
Journal of hepatology.
1998 May; 28(5):829-39. doi:
10.1016/s0168-8278(98)80234-1. [PMID: 9625319] - R D Duan, Y Cheng, H D Tauschel, A Nilsson. Effects of ursodeoxycholate and other bile salts on levels of rat intestinal alkaline sphingomyelinase: a potential implication in tumorigenesis.
Digestive diseases and sciences.
1998 Jan; 43(1):26-32. doi:
10.1023/a:1018807600683. [PMID: 9508530] - B L Lee, A L New, C N Ong. Comparative analysis of conjugated bile acids in human serum using high-performance liquid chromatography and capillary electrophoresis.
Journal of chromatography. B, Biomedical sciences and applications.
1997 Dec; 704(1-2):35-42. doi:
10.1016/s0378-4347(97)00443-x. [PMID: 9518169] - H Dai, H Jin, J He. [The changes of lipid metabolism and hemorrheology in intrahepatic cholestasis during pregnancy].
Zhonghua fu chan ke za zhi.
1997 Dec; 32(12):728-31. doi:
NULL. [PMID: 9772436] - P A Arns, A Adedoyin, A M DiBisceglie, J G Waggoner, J H Hoofnagle, G R Wilkinson, R A Branch. Mephenytoin disposition and serum bile acids as indices of hepatic function in chronic viral hepatitis.
Clinical pharmacology and therapeutics.
1997 Nov; 62(5):527-37. doi:
10.1016/s0009-9236(97)90048-5. [PMID: 9390109] - S Das, C D Schteingart, A F Hofmann, D S Reiner, S B Aley, F D Gillin. Giardia lamblia: evidence for carrier-mediated uptake and release of conjugated bile acids.
Experimental parasitology.
1997 Oct; 87(2):133-41. doi:
10.1006/expr.1997.4197. [PMID: 9326888] - A Yamamoto, S Okumura, Y Fukuda, M Fukui, K Takahashi, S Muranishi. Improvement of the pulmonary absorption of (Asu1,7)-eel calcitonin by various absorption enhancers and their pulmonary toxicity in rats.
Journal of pharmaceutical sciences.
1997 Oct; 86(10):1144-7. doi:
10.1021/js9603764. [PMID: 9344172] - M Y El-Mir, M J Monte, A I Morales, M Arevalo, M A Serrano, J J Marin. Effect of maternal cholestasis on biliary lipid and bile acid secretion in the infant rat.
Hepatology (Baltimore, Md.).
1997 Sep; 26(3):527-36. doi:
10.1002/hep.510260301. [PMID: 9303479] - V S Fedenko, I I Sheleketina, V S Struzhko. Infrared spectra of bile, ionized, and conjugated bile acids.
Ukrainskii biokhimicheskii zhurnal (1978).
1997 Jul; 69(4):66-71. doi:
NULL. [PMID: 9583125] - J J Criado, M C Herrera, M F Palomero, M Medarde, E Rodriguez, J J Marin. Synthesis and characterization of a new bile acid and platinum(II) complex with cytostatic activity.
Journal of lipid research.
1997 May; 38(5):1022-32. doi:
10.1016/s0022-2275(20)37226-6. [PMID: 9186919] - G R Villanueva, M E Mendoza, M Y el-Mir, M J Monte, M C Herrera, J J Marin. Effect of bile acids on hepatobiliary transport of cisplatin by perfused rat liver.
Pharmacology & toxicology.
1997 Mar; 80(3):111-7. doi:
10.1111/j.1600-0773.1997.tb00382.x. [PMID: 9101582] - X Wang, X Tang, T Xie, X Sun. The beneficial effects of anisodamine for CyA hepatotoxicity in the rat and in renal-transplant recipients.
Transplantation proceedings.
1997 Feb; 29(1-2):286-7. doi:
10.1016/s0041-1345(96)00096-6. [PMID: 9122998] - W Guo, M Wu, X Pei, D Guan, L Xu. A study on detection of serum fasting total bile acid and choloyglycin in neonate for cholestasis.
Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih.
1996 Dec; 11(4):244-7. doi:
NULL. [PMID: 9387392]