Oryzanin (BioDeep_00000227675)

   

human metabolite PANOMIX_OTCML-2023


代谢物信息卡片


5-(2-hydroxyethyl)-3-[(6-imino-2-methyl-1,6-dihydropyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium chloride

化学式: C12H17ClN4OS (300.0811542)
中文名称: 维生素 B1
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 65.15%

Reviewed

Last reviewed on 2024-08-13.

Cite this Page

Oryzanin. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/oryzanin (retrieved 2024-11-25) (BioDeep RN: BioDeep_00000227675). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: CC1=C(CCO)SC=[N+]1CC2=CN=C(C)N=C2N.[Cl-]
InChI: /p-1

描述信息

Oryzenin, also known as thiamin or vitamin b1, is a member of the class of compounds known as thiamines. Thiamines are compounds containing a thiamine moiety, which is structurally characterized by a 3-[(4-Amino-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-thiazol-5-yl backbone. Oryzenin is practically insoluble (in water) and an extremely weak acidic compound (based on its pKa). Oryzenin can be found in rice, which makes oryzenin a potential biomarker for the consumption of this food product.
A - Alimentary tract and metabolism > A11 - Vitamins > A11D - Vitamin b1, plain and in combination with vitamin b6 and b12 > A11DA - Vitamin b1, plain
D018977 - Micronutrients > D014815 - Vitamins
COVID info from COVID-19 Disease Map
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
Thiamine monochloride (Vitamin B1) is an essential vitamin that plays an important role in cellular production of energy from ingested food and enhances normal neuronal actives.
Thiamine monochloride (Vitamin B1) is an essential vitamin that plays an important role in cellular production of energy from ingested food and enhances normal neuronal actives.

同义名列表

10 个代谢物同义名

5-(2-hydroxyethyl)-3-[(6-imino-2-methyl-1,6-dihydropyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium chloride; 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium chloride; Thiamine monochloride; β-amin chloride; Vitamin B1; Thiaminum; Oryzenin; Thiamine; Thiamin; Tiamina



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yifei Lu, Chenqi Xu, Kewei Xie, Bingru Zhao, Minzhou Wang, Cheng Qian, Xuemei Chen, Leyi Gu, Wangshu Wu, Renhua Lu. The relationship between thiamin, folic acid and cognitive function in a rat model of uremia. Renal failure. 2024 Dec; 46(1):2329257. doi: 10.1080/0886022x.2024.2329257. [PMID: 38482596]
  • Viviane Maria de Sousa Fontes, Mércia de Sousa Galvão, Leila Moreira de Carvalho, Fabyan Laís do Nascimento Guedes, Marcos Dos Santos Lima, Taliana Kênia Alencar Bezerra, Marta Suely Madruga. Thiamine, cysteine and xylose added to the Maillard reaction of goat protein hydrolysate potentiates the formation of meat flavoring compounds. Food chemistry. 2024 Jul; 445(?):138398. doi: 10.1016/j.foodchem.2024.138398. [PMID: 38394903]
  • Xiying Xu, Chao Qi, Shuang Xu, Xinhao Fu, Zhiyuan Li, Hong Ren, Qian Qian, Shanshan Guo. Association between thiamine intake and depression: A national cross-sectional study. Journal of affective disorders. 2024 May; 352(?):259-266. doi: 10.1016/j.jad.2024.02.053. [PMID: 38367708]
  • Luiza Avezum, Yann E Madode, Christian Mestres, Nawel Achir, Charlotte Delpech, Morgane Chapron, Olivier Gibert, Loïc Rajjou, Eric Rondet. New insights into the rapid germination process of lentil and cowpea seeds: High thiamine and folate, and low α-galactoside content. Food chemistry. 2024 May; 439(?):138027. doi: 10.1016/j.foodchem.2023.138027. [PMID: 38029561]
  • V M Kodentsova, O V Kosheleva, O A Vrzhesinskaya, G V Guseva, V A Zotov, S N Leonenko, N V Zhilinskaya. [Influence of the rat diet enrichment with oat β-gucans on the assimilation of B group vitamins, mineral elements and lipid metabolism]. Voprosy pitaniia. 2024; 93(1):72-79. doi: 10.33029/0042-8833-2024-93-1-72-79. [PMID: 38555611]
  • Abida Kausar, Noreen Zahra, Hina Zahra, Muhammad Bilal Hafeez, Sara Zafer, Abida Shahzadi, Ali Raza, Ivica Djalovic, Pv Vara Prasad. Alleviation of drought stress through foliar application of thiamine in two varieties of pea (Pisum sativum L.). Plant signaling & behavior. 2023 Dec; 18(1):2186045. doi: 10.1080/15592324.2023.2186045. [PMID: 37016728]
  • Jin Yang, Lu Chen, Juan Zhang, Peng Liu, Ming Chen, Zhihui Chen, Kaili Zhong, Jiaqian Liu, Jianping Chen, Jian Yang. TaTHI2 interacts with Ca2+ -dependent protein kinase TaCPK5 to suppress virus infection by regulating ROS accumulation. Plant biotechnology journal. 2023 Dec; ?(?):. doi: 10.1111/pbi.14270. [PMID: 38100262]
  • Yi-Hsin Chung, Ting-Chieh Chen, Wen-Ju Yang, Soon-Ziet Chen, Jia-Ming Chang, Wei-Yu Hsieh, Ming-Hsiun Hsieh. Ectopic expression of a bacterial thiamin monophosphate kinase enhances vitamin B1 biosynthesis in plants. The Plant journal : for cell and molecular biology. 2023 Nov; ?(?):. doi: 10.1111/tpj.16563. [PMID: 37996996]
  • Chengyao Xia, Yuqiang Zhao, Lei Zhang, Xu Li, Yang Cheng, Dongming Wang, Changsheng Xu, Mengyi Qi, Jihong Wang, Xiangrui Guo, Xianfeng Ye, Yan Huang, Danyu Shen, Daolong Dou, Hui Cao, Zhoukun Li, Zhongli Cui. Myxobacteria restrain Phytophthora invasion by scavenging thiamine in soybean rhizosphere via outer membrane vesicle-secreted thiaminase I. Nature communications. 2023 Sep; 14(1):5646. doi: 10.1038/s41467-023-41247-0. [PMID: 37704617]
  • Ryan W Paerl, Nathaniel P Curtis, Meriel J Bittner, Melanie R Cohn, Scott M Gifford, Catherine C Bannon, Elden Rowland, Erin M Bertrand. Use and detection of a vitamin B1 degradation product yields new views of the marine B1 cycle and plankton metabolite exchange. mBio. 2023 08; 14(4):e0006123. doi: 10.1128/mbio.00061-23. [PMID: 37377416]
  • Kristen Van Gelder, Edmar R Oliveira-Filho, Jorge Donato García-García, You Hu, Steven D Bruner, Andrew D Hanson. Directed Evolution of Aerotolerance in Sulfide-Dependent Thiazole Synthases. ACS synthetic biology. 2023 04; 12(4):963-970. doi: 10.1021/acssynbio.2c00512. [PMID: 36920242]
  • Layla Al-Kharashi, Hala Attia, Aljazzy Alsaffi, Toka Almasri, Maha Arafa, Iman Hasan, Hanaa Alajami, Rehab Ali, Amira Badr. Pentoxifylline and thiamine ameliorate rhabdomyolysis-induced acute kidney injury in rats via suppressing TLR4/NF-κB and NLRP-3/caspase-1/gasdermin mediated-pyroptosis. Toxicology and applied pharmacology. 2023 Feb; 461(?):116387. doi: 10.1016/j.taap.2023.116387. [PMID: 36690085]
  • Laura M Ketelboeter, Shubhajit Mitra, Prasad Gyaneshwar. A thiamine transporter is required for biofilm formation by Rhizobium sp. IRBG74. FEMS microbiology letters. 2023 01; 370(?):. doi: 10.1093/femsle/fnad046. [PMID: 37253601]
  • Mehmet Kilincer, Hasan Saygin, Mustafa Ozyurek, Asli Baysal. Sorption of thiamin (vitamin B1) onto micro(nano)plastics: pH dependence and sorption models. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering. 2023; 58(8):762-772. doi: 10.1080/10934529.2023.2216123. [PMID: 37272070]
  • Henrique Moura Dias, Andreia Prata Vieira, Erika Maria de Jesus, Nathalia de Setta, Gesiele Barros, Marie-Anne Van Sluys. Functional and comparative analysis of THI1 gene in grasses with a focus on sugarcane. PeerJ. 2023; 11(?):e14973. doi: 10.7717/peerj.14973. [PMID: 37214086]
  • Ryan G Lim, Osama Al-Dalahmah, Jie Wu, Maxwell P Gold, Jack C Reidling, Guomei Tang, Miriam Adam, David K Dansu, Hye-Jin Park, Patrizia Casaccia, Ricardo Miramontes, Andrea M Reyes-Ortiz, Alice Lau, Richard A Hickman, Fatima Khan, Fahad Paryani, Alice Tang, Kenneth Ofori, Emily Miyoshi, Neethu Michael, Nicolette McClure, Xena E Flowers, Jean Paul Vonsattel, Shawn Davidson, Vilas Menon, Vivek Swarup, Ernest Fraenkel, James E Goldman, Leslie M Thompson. Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation. Nature communications. 2022 12; 13(1):7791. doi: 10.1038/s41467-022-35388-x. [PMID: 36543778]
  • M Sathiyabama, M Gandhi, M Indhumathi. Suppression of dry root rot disease caused by Rhizoctonia bataticola (Taub.) Butler in chickpea plants by application of thiamine loaded chitosan nanoparticles. Microbial pathogenesis. 2022 Dec; 173(Pt B):105893. doi: 10.1016/j.micpath.2022.105893. [PMID: 36417974]
  • Birgitta Ryback, Miriam Bortfeld-Miller, Julia A Vorholt. Metabolic adaptation to vitamin auxotrophy by leaf-associated bacteria. The ISME journal. 2022 12; 16(12):2712-2724. doi: 10.1038/s41396-022-01303-x. [PMID: 35987782]
  • Julian Bleicher, Elmar E Ebner, Kathrine H Bak. Formation and Analysis of Volatile and Odor Compounds in Meat-A Review. Molecules (Basel, Switzerland). 2022 Oct; 27(19):. doi: 10.3390/molecules27196703. [PMID: 36235239]
  • Xinyang Li, Yingyi Mao, Shuang Liu, Jin Wang, Xiang Li, Yanrong Zhao, David R Hill, Shuo Wang. Vitamins, Vegetables and Metal Elements Are Positively Associated with Breast Milk Oligosaccharide Composition among Mothers in Tianjin, China. Nutrients. 2022 Oct; 14(19):. doi: 10.3390/nu14194131. [PMID: 36235783]
  • Depeng Wang, Yabing Meng, Fangang Meng. Genome-centric metagenomics insights into functional divergence and horizontal gene transfer of denitrifying bacteria in anammox consortia. Water research. 2022 Oct; 224(?):119062. doi: 10.1016/j.watres.2022.119062. [PMID: 36116192]
  • Serap Andac-Ozturk, Gökçen Garipoğlu, Jale Çatak, Mustafa Yaman. Investigation of the vitamins B1, B2, and B6 vitamers bioaccessibilities of canned, dried legumes after in vitro gastrointestinal digestion system. Food research international (Ottawa, Ont.). 2022 10; 160(?):111671. doi: 10.1016/j.foodres.2022.111671. [PMID: 36076445]
  • Roberta Vitali, Clara Prioreschi, Laura Lorenzo Rebenaque, Eleonora Colantoni, Daniela Giovannini, Sarah Frusciante, Gianfranco Diretto, Francisco Marco-Jiménez, Mariateresa Mancuso, Arianna Casciati, Simonetta Pazzaglia. Gut-Brain Axis: Insights from Hippocampal Neurogenesis and Brain Tumor Development in a Mouse Model of Experimental Colitis Induced by Dextran Sodium Sulfate. International journal of molecular sciences. 2022 Sep; 23(19):. doi: 10.3390/ijms231911495. [PMID: 36232813]
  • Wei-Yu Hsieh, Hsin-Mei Wang, Yi-Hsin Chung, Kim-Teng Lee, Hong-Sheng Liao, Ming-Hsiun Hsieh. THIAMIN REQUIRING2 is involved in thiamin diphosphate biosynthesis and homeostasis. The Plant journal : for cell and molecular biology. 2022 09; 111(5):1383-1396. doi: 10.1111/tpj.15895. [PMID: 35791282]
  • Marcel Llavero-Pasquina, Katrin Geisler, Andre Holzer, Payam Mehrshahi, Gonzalo I Mendoza-Ochoa, Shelby A Newsad, Matthew P Davey, Alison G Smith. Thiamine metabolism genes in diatoms are not regulated by thiamine despite the presence of predicted riboswitches. The New phytologist. 2022 09; 235(5):1853-1867. doi: 10.1111/nph.18296. [PMID: 35653609]
  • Tanner B Call, Emma K Davis, Joseph D Bean, Skyler G Lemmon, John M Chaston. Bacterial Metabolism and Transport Genes Are Associated with the Preference of Drosophila melanogaster for Dietary Yeast. Applied and environmental microbiology. 2022 08; 88(16):e0072022. doi: 10.1128/aem.00720-22. [PMID: 35913151]
  • Yanshen Nie, Li Yu, Lianlian Mao, Wenxuan Zou, Xiufeng Zhang, Jie Zhao. Vitamin B1 THIAMIN REQUIRING1 synthase mediates the maintenance of chloroplast function by regulating sugar and fatty acid metabolism in rice. Journal of integrative plant biology. 2022 Aug; 64(8):1575-1595. doi: 10.1111/jipb.13283. [PMID: 35603832]
  • Tomoko Fujii, Yugeesh R Lankadeva, Rinaldo Bellomo. Update on vitamin C administration in critical illness. Current opinion in critical care. 2022 Aug; 28(4):374-380. doi: 10.1097/mcc.0000000000000951. [PMID: 35797532]
  • Eva Laverdure, Catherine Sperlich, Susan Fox. Refractory immune TTP following Pfizer-BioNTech COVID-19 vaccine successfully salvaged with caplacizumab. Journal of thrombosis and haemostasis : JTH. 2022 Jul; 20(7):1696-1698. doi: 10.1111/jth.15751. [PMID: 35510743]
  • Weixi Li, Xinyue Mi, Xuanxiang Jin, Daiwei Zhang, Guozhong Zhu, Xiaoguang Shang, Dayong Zhang, Wangzhen Guo. Thiamine functions as a key activator for modulating plant health and broad-spectrum tolerance in cotton. The Plant journal : for cell and molecular biology. 2022 07; 111(2):374-390. doi: 10.1111/tpj.15793. [PMID: 35506325]
  • Mahtab Ghanbari Rad, Mohammadreza Sharifi, Rokhsareh Meamar, Nepton Soltani. The role of pancreas to improve hyperglycemia in STZ-induced diabetic rats by thiamine disulfide. Nutrition & diabetes. 2022 06; 12(1):32. doi: 10.1038/s41387-022-00211-5. [PMID: 35725834]
  • Ying Liu, Ziwei Qin, Ning Chen, Zhigang Bu, Yuanzhu Yang, Xiaochun Hu, Heping Zheng, Zhuoyi Zhu, Ting Xu, Yan Gao, Shuqi Niu, Junjie Xing, Jianzhong Lin, Xuanming Liu, Yonghua Zhu. The Vital Role of ShTHIC from the Endophyte OsiSh-2 in Thiamine Biosynthesis and Blast Resistance in the OsiSh-2-Rice Symbiont. Journal of agricultural and food chemistry. 2022 Jun; 70(23):6993-7003. doi: 10.1021/acs.jafc.2c00776. [PMID: 35667655]
  • Prachi Saluja, Nitesh Gautam, Sisira Yadala, Anand N Venkata. Thrombotic thrombocytopenic purpura (TTP) after COVID-19 vaccination: A systematic review of reported cases. Thrombosis research. 2022 06; 214(?):115-121. doi: 10.1016/j.thromres.2022.04.020. [PMID: 35533526]
  • Takahiro Yamashiro, Tomoya Yasujima, Hiroaki Yuasa. Animal species differences in the pyridoxine transport function of SLC19A3: Absence of Slc19a3-mediated pyridoxine uptake in the rat small intestine. Drug metabolism and pharmacokinetics. 2022 Jun; 44(?):100456. doi: 10.1016/j.dmpk.2022.100456. [PMID: 35512554]
  • Elaheh Amirani, Esmat Aghadavod, Rana Shafabakhsh, Zatollah Asemi, Zohreh Tabassi, Ida Panahandeh, Fatemeh Naderi, Alireza Abed. Anti-inflammatory and antioxidative effects of thiamin supplements in patients with gestational diabetes mellitus. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 2022 Jun; 35(11):2085-2090. doi: 10.1080/14767058.2020.1779212. [PMID: 32722956]
  • Kieran V Allowitz, John J Yoo, Justin R Taylor, Omar A Baloch, Kyra Harames, Kota V Ramana. Therapeutic potential of vitamin B1 derivative benfotiamine from diabetes to COVID-19. Future medicinal chemistry. 2022 06; 14(11):809-826. doi: 10.4155/fmc-2022-0040. [PMID: 35535731]
  • Lucile Equey, Philipp K A Agyeman, Rosemarie Veraguth, Serge Rezzi, Luregn J Schlapbach, Eric Giannoni. Serum Ascorbic Acid and Thiamine Concentrations in Sepsis: Secondary Analysis of the Swiss Pediatric Sepsis Study. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 2022 05; 23(5):390-394. doi: 10.1097/pcc.0000000000002911. [PMID: 35583617]
  • Donogh Maguire, Alana Burns, Dinesh Talwar, Anthony Catchpole, Fiona Stefanowicz, David P Ross, Peter Galloway, Alastair Ireland, Gordon Robson, Michael Adamson, Lesley Orr, Joanna-Lee Kerr, Xenofon Roussis, Eoghan Colgan, Ewan Forrest, David Young, Donald C McMillan. Randomised trial of intravenous thiamine and/or magnesium sulphate administration on erythrocyte transketolase activity, lactate concentrations and alcohol withdrawal scores. Scientific reports. 2022 04; 12(1):6941. doi: 10.1038/s41598-022-10970-x. [PMID: 35484175]
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  • Ayed Al-Anezi, Vania Sotirova-Koulli, Osama Shalaby, Ahmed Ibrahim, Nehad Abdulmotagalli, Ramy Youssef, Mohamed Hossam El-Din. Biotin-thiamine responsive basal ganglia disease in the era of COVID-19 outbreak diagnosis not to be missed: A case report. Brain & development. 2022 Apr; 44(4):303-307. doi: 10.1016/j.braindev.2021.12.003. [PMID: 34953623]
  • Simon Strobbe, Jana Verstraete, Teresa B Fitzpatrick, Maria Faustino, Tiago F Lourenço, M Margarida Oliveira, Christophe Stove, Dominique Van Der Straeten. A novel panel of yeast assays for the assessment of thiamin and its biosynthetic intermediates in plant tissues. The New phytologist. 2022 04; 234(2):748-763. doi: 10.1111/nph.17974. [PMID: 35037254]
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