Nicotinamide adenine dinucleotide (BioDeep_00000018609)

   

human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite BioNovoGene_Lab2019


代谢物信息卡片


1-[(2R,3R,4S,5R)-5-({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono}oxy)(hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxyoxolan-2-yl]-3-(C-hydroxycarbonimidoyl)-1lambda5-pyridin-1-ylium

化学式: C21H27N7O14P2 (663.1091182)
中文名称: β-烟酰胺腺嘌呤二核苷酸(NAD), β-烟酰胺腺嘌呤二核苷酸, 烟酰胺腺嘌呤二核苷酸
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 28.81%

Reviewed

Last reviewed on 2024-09-13.

Cite this Page

Nicotinamide adenine dinucleotide. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/nicotinamide_adenine_dinucleotide (retrieved 2024-11-25) (BioDeep RN: BioDeep_00000018609). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)([O-])OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N
InChI: InChI=1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1

描述信息

NAD (or Nicotinamide adenine dinucleotide) is used extensively in glycolysis and the citric acid cycle of cellular respiration. The reducing potential stored in NADH can be converted to ATP through the electron transport chain or used for anabolic metabolism. ATP "energy" is necessary for an organism to live. Green plants obtain ATP through photosynthesis, while other organisms obtain it by cellular respiration. (wikipedia). Nicotinamide adenine dinucleotide is a A coenzyme composed of ribosylnicotinamide 5-diphosphate coupled to adenosine 5-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) [HMDB]
NAD (or nicotinamide adenine dinucleotide) is used extensively in glycolysis and the citric acid cycle of cellular respiration. The reducing potential stored in NADH can be either converted into ATP through the electron transport chain or used for anabolic metabolism. ATP "energy" is necessary for an organism to live. Green plants obtain ATP through photosynthesis, while other organisms obtain it via cellular respiration (Wikipedia). NAD is a coenzyme composed of ribosylnicotinamide 5-diphosphate coupled to adenosine 5-phosphate by a pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH) (Dorland, 27th ed).
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NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.
NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.

同义名列表

33 个代谢物同义名

1-[(2R,3R,4S,5R)-5-({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono}oxy)(hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxyoxolan-2-yl]-3-(C-hydroxycarbonimidoyl)-1lambda5-pyridin-1-ylium; 1-[(2R,3R,4S,5R)-5-{[({[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono}oxy(hydroxy)phosphoryl)oxy]methyl}-3,4-dihydroxyoxolan-2-yl]-3-(C-hydroxycarbonimidoyl)-1lambda5-pyridin-1-ylium; beta-Nicotinamide adenine dinucleotide hydrate; β-Nicotinamide adenine dinucleotide hydrate; Dinucleotide, dihydronicotinamide adenine; Adenine dinucleotide, dihydronicotinamide; Dihydronicotinamide adenine dinucleotide; beta-Nicotinamide adenine dinucleotide; Oxidized diphosphopyridine nucleotide; β-Nicotinamide adenine dinucleotide; Dinucleotide, nicotinamide-adenine; Nicotinamide adenine dinucleotide; Nicotinamide-adenine dinucleotide; Adenine-nicotinamide dinucleotide; NICOTINAMIDE-adenine-dinucleotide; beta-Diphosphopyridine nucleotide; β-Diphosphopyridine nucleotide; Nucleotide, diphosphopyridine; Diphosphopyridine nucleotide; Codehydrogenase I; Cozymase I; Coenzyme I; beta-NAD+; beta-NAD; β-NAD+; Nadide; β-NAD; NADH; NAD+; DPN; NAD; β-DPN; NAD+



数据库引用编号

22 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

7 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(6)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(1)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Simeng He, Xianhong Jiang, Jing Yang, Ya Wu, Jia Shi, Xiaoyang Wu, Shihan Du, Yuan Zhang, Lirong Gong, Shuan Dong, Jianbo Yu. Nicotinamide mononucleotide alleviates endotoxin-induced acute lung injury by modulating macrophage polarization via the SIRT1/NF-κB pathway. Pharmaceutical biology. 2024 Dec; 62(1):22-32. doi: 10.1080/13880209.2023.2292256. [PMID: 38100537]
  • Shiya Huang, Xueqian Huang, Xiaohui Wen, Xuehong Liu, Hongxia Ma, Linling Xie, Yishu Wang, Shanjia Liu, Yongge Guan, Kunyin Li. Enhanced glycolysis in the myometrium with ectopic endometrium of patients with adenomyosis: a preliminary study. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. 2024 Dec; 40(1):2332411. doi: 10.1080/09513590.2024.2332411. [PMID: 38537663]
  • Jing Li, Litao Zhang, Wenjie Yu, Mengjie Zhang, Feng Chen, Jianguo Liu. Mitochondrial alternative oxidase pathway accelerates non-motile cell germination by enhancing respiratory carbon metabolism and maintaining redox poise in Haematococcus pluvialis. Bioresource technology. 2024 Jun; 402(?):130729. doi: 10.1016/j.biortech.2024.130729. [PMID: 38657826]
  • Maike Cosse, Tanja Rehders, Jürgen Eirich, Iris Finkemeier, Jennifer Selinski. Cysteine oxidation as a regulatory mechanism of Arabidopsis plastidial NAD-dependent malate dehydrogenase. Physiologia plantarum. 2024 May; 176(3):e14340. doi: 10.1111/ppl.14340. [PMID: 38741259]
  • Anchal Garg, Payal Srivastava, Praveen Chandra Verma, Sumit Ghosh. ApCPS2 contributes to medicinal diterpenoid biosynthesis and defense against insect herbivore in Andrographis paniculata. Plant science : an international journal of experimental plant biology. 2024 May; 342(?):112046. doi: 10.1016/j.plantsci.2024.112046. [PMID: 38395069]
  • Quan Ma, Jianzhao Liu, Hao Hu, Zisheng Luo. The uncharted territory of NAD+-capped RNA. Trends in cell biology. 2024 May; 34(5):355-359. doi: 10.1016/j.tcb.2023.12.005. [PMID: 38242774]
  • Lijie Gu, Yanhong Du, Jianglei Chen, Mohammad Nazmul Hasan, Yung Dai Clayton, David J Matye, Jacob E Friedman, Tiangang Li. Cullin 3 RING E3 ligase inactivation causes NRF2-dependent NADH reductive stress, hepatic lipodystrophy, and systemic insulin resistance. Proceedings of the National Academy of Sciences of the United States of America. 2024 Apr; 121(17):e2320934121. doi: 10.1073/pnas.2320934121. [PMID: 38630726]
  • Ritamaria Di Lorenzo, Danila Falanga, Lucia Ricci, Antonio Colantuono, Giovanni Greco, Maura Angelillo, Fiorella Nugnes, Teresa Di Serio, Dorothea Costa, Annalisa Tito, Sonia Laneri. NAD-Driven Sirtuin Activation by Cordyceps sinensis Extract: Exploring the Adaptogenic Potential to Promote Skin Longevity. International journal of molecular sciences. 2024 Apr; 25(8):. doi: 10.3390/ijms25084282. [PMID: 38673866]
  • Wenjing Ouyang, Emilie Wientjes, Peter E L van der Putten, Ludovico Caracciolo, Ruixuan Zhao, Collins Agho, Maurizio Junior Chiurazzi, Marius Bongers, Paul C Struik, Herbert van Amerongen, Xinyou Yin. Roles for leakiness and O2 evolution in explaining lower-than-theoretical quantum yields of photosynthesis in the PEP-CK subtype of C4 plants. The New phytologist. 2024 Apr; 242(2):431-443. doi: 10.1111/nph.19614. [PMID: 38406986]
  • Parimalan Rangan, Agnelo Furtado, Viswanathan Chinnusamy, Robert Henry. A multi-cell model for the C4 photosynthetic pathway in developing wheat grains based upon tissue-specific transcriptome data. Bio Systems. 2024 Apr; 238(?):105195. doi: 10.1016/j.biosystems.2024.105195. [PMID: 38555052]
  • Emily A Pinheiro, Jean-Marc DeKeyser, Brian Lenny, Yadav Sapkota, Paul W Burridge. Nilotinib-induced alterations in endothelial cell function recapitulate clinical vascular phenotypes independent of ABL1. Scientific reports. 2024 03; 14(1):7123. doi: 10.1038/s41598-024-57686-8. [PMID: 38532120]
  • Ke Wang, Xueqing Liu, Kevin K Y Hu, Victoria S Haritos. Artificial Methylotrophic Cells via Bottom-Up Integration of a Methanol-Utilizing Pathway. ACS synthetic biology. 2024 Mar; 13(3):888-900. doi: 10.1021/acssynbio.3c00683. [PMID: 38359048]
  • Franziska Gütgemann, Annet Heuvelink, Anja Müller, Yury Churin, Rianne Buter, Arne Jung, Anneke Feberwee, Jeanine Wiegel, Franziska Kumm, Ann Sophie Braun, Min Yue, Edgardo Soriano-Vargas, Stefan Swanepoel, Nadine Botteldoorn, Miranda Kirchner, Corinna Kehrenberg. Recommendation of a standardized broth microdilution method for antimicrobial susceptibility testing of Avibacterium paragallinarum and resistance monitoring. Journal of clinical microbiology. 2024 Mar; 62(3):e0101123. doi: 10.1128/jcm.01011-23. [PMID: 38363142]
  • Xufeng Wang, Dongli Yu, Jiancheng Yu, Hao Hu, Runlai Hang, Zachary Amador, Qi Chen, Jijie Chai, Xuemei Chen. Toll/interleukin-1 receptor (TIR) domain-containing proteins have NAD-RNA decapping activity. Nature communications. 2024 Mar; 15(1):2261. doi: 10.1038/s41467-024-46499-y. [PMID: 38480720]
  • Wen Song, Li Liu, Dongli Yu, Hanna Bernardy, Jan Jirschitzka, Shijia Huang, Aolin Jia, Wictoria Jemielniak, Julia Acker, Henriette Laessle, Junli Wang, Qiaochu Shen, Weijie Chen, Pilong Li, Jane E Parker, Zhifu Han, Paul Schulze-Lefert, Jijie Chai. Substrate-induced condensation activates plant TIR domain proteins. Nature. 2024 Mar; 627(8005):847-853. doi: 10.1038/s41586-024-07183-9. [PMID: 38480885]
  • Yuho Kim, Hailey A Parry, T Bradley Willingham, Greg Alspaugh, Eric Lindberg, Christian A Combs, Jay R Knutson, Christopher K E Bleck, Brian Glancy. Reorganization of mitochondria-organelle interactions during postnatal development in skeletal muscle. The Journal of physiology. 2024 Mar; 602(5):891-912. doi: 10.1113/jp285014. [PMID: 38429930]
  • Claire McDonald, Craig Alderson, Matthew G Birkbeck, Laura Brown, Silvia Del Din, Grainne G Gorman, Kieren Hollingsworth, Clare Massarella, Rana Rehman, Lynn Rochester, Avan Ap Sayer, Huizhong Su, Helen Tuppen, Charlotte Warren, Miles D Witham. A study protocol to investigate if acipimox improves muscle function and sarcopenia: an open-label, uncontrolled, before-and-after experimental medicine feasibility study in community-dwelling older adults. BMJ open. 2024 Feb; 14(2):e076518. doi: 10.1136/bmjopen-2023-076518. [PMID: 38417968]
  • Di-Yang Sun, Wen-Bin Wu, Jian-Jin Wu, Yu Shi, Jia-Jun Xu, Shen-Xi Ouyang, Chen Chi, Yi Shi, Qing-Xin Ji, Jin-Hao Miao, Jiang-Tao Fu, Jie Tong, Ping-Ping Zhang, Jia-Bao Zhang, Zhi-Yong Li, Le-Feng Qu, Fu-Ming Shen, Dong-Jie Li, Pei Wang. Pro-ferroptotic signaling promotes arterial aging via vascular smooth muscle cell senescence. Nature communications. 2024 Feb; 15(1):1429. doi: 10.1038/s41467-024-45823-w. [PMID: 38365899]
  • Qinghai Qiao, Xin Wang, Zhiyuan Su, Chenyang Han, Keke Zhao, Kaijie Qi, Zhihua Xie, Xiaosan Huang, Shaoling Zhang. PuNDH9, a subunit of ETC Complex I regulates plant defense by interacting with PuPR1. Plant science : an international journal of experimental plant biology. 2024 Feb; ?(?):112009. doi: 10.1016/j.plantsci.2024.112009. [PMID: 38316345]
  • Xiaojing Wei, Yutian Tan, Jiaqi Huang, Ximing Dong, Weijie Feng, Tanglin Liu, Zhao Yang, Guiying Yang, Xiao Luo. N1-methylnicotinamide impairs gestational glucose tolerance in mice. Journal of molecular endocrinology. 2024 Feb; 72(2):. doi: 10.1530/jme-23-0126. [PMID: 38029302]
  • Josephine Yu, Neil A Youngson, D Ross Laybutt, Margaret J Morris, Sarah-Jane Leigh. Complementary yet divergent effects of exercise and an exercise mimetic on microbiome in high-fat diet-induced obesity. Physiological genomics. 2024 Feb; 56(2):136-144. doi: 10.1152/physiolgenomics.00066.2023. [PMID: 38009223]
  • Xi Chen, Zhenchuan Wang, Chen Li, Zhao Zhang, Shan Lu, Xuanzhong Wang, Qi Liang, Xiaoxi Zhu, Chengliang Pan, Qingxuan Wang, Zhilin Ji, Yubo Wang, Meihua Piao, Guangfan Chi, Pengfei Ge. SIRT1 activated by AROS sensitizes glioma cells to ferroptosis via induction of NAD+ depletion-dependent activation of ATF3. Redox biology. 2024 Feb; 69(?):103030. doi: 10.1016/j.redox.2024.103030. [PMID: 38181705]
  • Mei-Yu Zhang, Xin-Ru Xu, Ru-Ping Zhao, Chao Huang, Yuan-Da Song, Zi-Tong Zhao, Yu-Bin Zhao, Xiao-Jie Ren, Xin-He Zhao. Mechanism of enhanced microalgal biomass and lipid accumulation through symbiosis between a highly succinic acid-producing strain of Escherichia coli SUC and Aurantiochytrium sp. SW1. Bioresource technology. 2024 Feb; 394(?):130232. doi: 10.1016/j.biortech.2023.130232. [PMID: 38141881]
  • Hao Yu, Daojing Gan, Zhen Luo, Qilin Yang, Dongqi An, Hao Zhang, Yingchun Hu, Zhuang Ma, Qingchun Zeng, Dingli Xu, Hao Ren. α-Ketoglutarate improves cardiac insufficiency through NAD+-SIRT1 signaling-mediated mitophagy and ferroptosis in pressure overload-induced mice. Molecular medicine (Cambridge, Mass.). 2024 Jan; 30(1):15. doi: 10.1186/s10020-024-00783-1. [PMID: 38254035]
  • Tonghui Wang, Jinbo Fei, Zhenzhen Dong, Fanchen Yu, Junbai Li. Nanoarchitectonics with a Membrane-Embedded Electron Shuttle Mimics the Bioenergy Anabolism of Mitochondria. Angewandte Chemie (International ed. in English). 2024 Jan; ?(?):e202319116. doi: 10.1002/anie.202319116. [PMID: 38225920]
  • Limin Liu, Yulin Ye, Rui Lin, Tianyu Liu, Sinan Wang, Zelin Feng, Xiaoli Wang, Hailong Cao, Xin Chen, Junming Miao, Yifei Liu, Kui Jiang, Zhibo Han, Zongjin Li, Xiaocang Cao. Ferroptosis: a promising candidate for exosome-mediated regulation in different diseases. Cell communication and signaling : CCS. 2024 01; 22(1):6. doi: 10.1186/s12964-023-01369-w. [PMID: 38166927]
  • Shan Shen, Mingyang Shen, Lirun Kuang, Keyu Yang, Shiran Wu, Xinde Liu, Yuting Wang, Yong Wang. SIRT1/SREBPs-mediated regulation of lipid metabolism. Pharmacological research. 2024 Jan; 199(?):107037. doi: 10.1016/j.phrs.2023.107037. [PMID: 38070792]
  • Edgar Willibaldo Allebrandt Neto, Jadyellen Rondon E Silva, Stephanie Figueiredo Santos, Suélem Aparecida de França Lemes, Nair Honda Kawashita, Mayara Peron Pereira. The futile creatine cycle and the synthesis of fatty acids in inguinal white adipose tissue from growing rats, submitted to a hypoprotein-hyperglycidic diet for 15 days. Lipids. 2024 Jan; 59(1):3-12. doi: 10.1002/lipd.12384. [PMID: 38223990]
  • Chaomurilege, Atsuko Miyagi, Toshiki Ishikawa, Masatoshi Yamaguchi, Hideki Murayama, Maki Kawai-Yamada. Metabolic changes associated with dark-induced leaf senescence in Arabidopsis nadk2 mutants. Plant signaling & behavior. 2023 12; 18(1):2215618. doi: 10.1080/15592324.2023.2215618. [PMID: 37272565]
  • Chao Dai, Mengqian Hou, Xudong Yang, Zhefeng Wang, Changpo Sun, Xin Wu, Shujin Wang. Increased NAD+ levels protect female mouse reproductive system against zearalenone-impaired glycolysis, lipid metabolism, antioxidant capacity and inflammation. Reproductive toxicology (Elmsford, N.Y.). 2023 Dec; 124(?):108530. doi: 10.1016/j.reprotox.2023.108530. [PMID: 38159578]
  • Liwen Gao, Xi Huang, Ruyu Deng, Shanshan Wu, Yu Peng, Guoliang Xiong, Jiandong Lu, Xinhui Liu. Jian-Pi-Yi-Shen formula alleviates renal fibrosis by restoring NAD+ biosynthesis in vivo and in vitro. Aging. 2023 Dec; 16(1):106-128. doi: 10.18632/aging.205352. [PMID: 38157259]
  • Dan Sun, Guohua Qi, Xuan Yi, Hongyan Zhu, Yongdong Jin. Smart Ratiometric SERS Nanoprobe for Real-Time Monitoring Hydrogen Peroxide in Living Cells during NADH Treatment Associated with Ferroptosis. Analytical chemistry. 2023 Dec; 95(49):18075-18081. doi: 10.1021/acs.analchem.3c02912. [PMID: 38030577]
  • Katayoun Zamani, Motahhareh Mohsenpour, Mohammad Ali Malboobi. Predicting the allergenic risk of Phosphite-NAD+-Oxidoreductase and purple acid phosphatase 17 proteins in genetically modified canola using bioinformatic approaches. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023 Dec; 182(?):114094. doi: 10.1016/j.fct.2023.114094. [PMID: 37925014]
  • Lili Cheng, R N V Krishna Deepak, Guoqiang Wang, Ziyi Meng, Lei Tao, Mengqing Xie, Wenna Chi, Yuming Zhang, Mingming Yang, Yilie Liao, Ruiqun Chen, Yu Liang, Junyu Zhang, Yuedong Huang, Weihua Wang, Zhiying Guo, Yunfang Wang, Jiandie D Lin, Hao Fan, Ligong Chen. Hepatic mitochondrial NAD + transporter SLC25A47 activates AMPKα mediating lipid metabolism and tumorigenesis. Hepatology (Baltimore, Md.). 2023 Dec; 78(6):1828-1842. doi: 10.1097/hep.0000000000000314. [PMID: 36804859]
  • Mikako Yagi, Yura Do, Haruka Hirai, Kenji Miki, Takahiro Toshima, Yukina Fukahori, Daiki Setoyama, Chiaki Abe, Yo-Ichi Nabeshima, Dongchon Kang, Takeshi Uchiumi. Improving lysosomal ferroptosis with NMN administration protects against heart failure. Life science alliance. 2023 Dec; 6(12):. doi: 10.26508/lsa.202302116. [PMID: 37793777]
  • Alise Zagare, German Preciat, Sarah L Nickels, Xi Luo, Anna S Monzel, Gemma Gomez-Giro, Graham Robertson, Christian Jaeger, Jafar Sharif, Haruhiko Koseki, Nico J Diederich, Enrico Glaab, Ronan M T Fleming, Jens C Schwamborn. Omics data integration suggests a potential idiopathic Parkinson's disease signature. Communications biology. 2023 11; 6(1):1179. doi: 10.1038/s42003-023-05548-w. [PMID: 37985891]
  • Xing Gao, Lele Jian, Lijun Zhang, Yuqiao Xu, Yuanlin Zhao, Ying Yang, Yuan Yuan, Yuying Wang, Shenhui Xu, Bincheng Ren, Zimeng Li, Chao Wang, Jing Li, Yu Gu, Jing Ye. Perilipin 5 protects the mitochondrial oxidative functions and improves the alcoholic liver injury in mice. Liver international : official journal of the International Association for the Study of the Liver. 2023 Nov; ?(?):. doi: 10.1111/liv.15775. [PMID: 37933091]
  • Shoki Ito, Atsuko Watanabe, Takashi Osanai. Regulation of l-aspartate oxidase contributes to NADP+ biosynthesis in Synechocystis sp. PCC 6803. Plant physiology. 2023 Nov; ?(?):. doi: 10.1093/plphys/kiad580. [PMID: 37936332]
  • Huijuan Zhou, Mingshen Su, Jihong Du, Xianan Zhang, Xiongwei Li, Minghao Zhang, Yang Hu, Chen Huan, Zhengwen Ye. Crucial roles of sorbitol metabolism and energy status in the chilling tolerance of yellow peach. Plant physiology and biochemistry : PPB. 2023 Nov; 204(?):108092. doi: 10.1016/j.plaphy.2023.108092. [PMID: 37852068]
  • Toshitaka Nakamura, Eikan Mishima, Naoya Yamada, André Santos Dias Mourão, Dietrich Trümbach, Sebastian Doll, Jonas Wanninger, Elena Lytton, Peter Sennhenn, Thamara Nishida Xavier da Silva, José Pedro Friedmann Angeli, Michael Sattler, Bettina Proneth, Marcus Conrad. Integrated chemical and genetic screens unveil FSP1 mechanisms of ferroptosis regulation. Nature structural & molecular biology. 2023 Nov; 30(11):1806-1815. doi: 10.1038/s41594-023-01136-y. [PMID: 37957306]
  • Eeva M Marttinen, Eva L Decker, Petra Heinonen, Ralf Reski, Jari P T Valkonen. Putative NAD(P)-Binding Rossmann Fold Protein Is Involved in Chitosan-Induced Peroxidase Activity and Lipoxygenase Expression in Physcomitrium patens. Molecular plant-microbe interactions : MPMI. 2023 Nov; 36(11):682-692. doi: 10.1094/mpmi-07-23-0094-r. [PMID: 37486175]
  • Agata Jacewicz, Swathi Dantuluri, Stewart Shuman. Structural basis for Tpt1-catalyzed 2'-PO4 transfer from RNA and NADP(H) to NAD. Proceedings of the National Academy of Sciences of the United States of America. 2023 Oct; 120(44):e2312999120. doi: 10.1073/pnas.2312999120. [PMID: 37883434]
  • Jinxing Du, Jiaqi Shao, Shengjie Li, Tao Zhu, Hongmei Song, Caixia Lei, Meng Zhang, Yingkun Cen. Integrated transcriptomic and proteomic analyses reveal the mechanism of easy acceptance of artificial pelleted diets during food habit domestication in Largemouth bass (Micropterus salmoides). Scientific reports. 2023 10; 13(1):18461. doi: 10.1038/s41598-023-45645-8. [PMID: 37891233]
  • Qi Li, Mingxi Zhou, Shweta Chhajed, Fahong Yu, Sixue Chen, Yanping Zhang, Zhonglin Mou. N-hydroxypipecolic acid triggers systemic acquired resistance through extracellular NAD(P). Nature communications. 2023 Oct; 14(1):6848. doi: 10.1038/s41467-023-42629-0. [PMID: 37891163]
  • Ashkan Kalantary-Charvadeh, Saeed Nazari Soltan Ahmad, Somayeh Aslani, Mehdi Beyrami, Mehran Mesgari-Abbasi. β-lapachone protects against doxorubicin-induced hepatotoxicity through modulation of NAD+ /SIRT-1/FXR/p-AMPK/NF-kB and Nrf2 signaling axis. Journal of biochemical and molecular toxicology. 2023 Oct; ?(?):e23564. doi: 10.1002/jbt.23564. [PMID: 37867446]
  • Hsiang Chang, Yen-Ting Chen, Hsiang-En Huang, Mang-Jye Ger. Overexpressing plant ferredoxin-like protein enhances photosynthetic efficiency and carbohydrates accumulation in Phalaenopsis. Transgenic research. 2023 Oct; ?(?):. doi: 10.1007/s11248-023-00370-w. [PMID: 37851307]
  • Mengdi Chen, Zhengbo Wang, Ziyuan Hao, Hongying Li, Qi Feng, Xue Yang, Xiaojiao Han, Xiping Zhao. Screening and Validation of Appropriate Reference Genes for Real-Time Quantitative PCR under PEG, NaCl and ZnSO4 Treatments in Broussonetia papyrifera. International journal of molecular sciences. 2023 Oct; 24(20):. doi: 10.3390/ijms242015087. [PMID: 37894768]
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  • Mahmoud M A Abulmeaty, Hazem K Ghneim, Ali Madi Almajwal, Suhail Razak, Abdulaziz S AlSahli, Juan E Andrade Laborde, Ebtesam M Ibrahim, Mourad A M Aboul-Soud, Yazeed A Al-Sheikh. Effects of unpredictable chronic mild stress on the cellular redox state and mitochondrial energy homeostasis in rat adipose tissue: A comprehensive metabolic study. Cell biochemistry and function. 2023 Oct; ?(?):. doi: 10.1002/cbf.3867. [PMID: 37805950]
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  • Toshitaka Nakamura, Clara Hipp, André Santos Dias Mourão, Jan Borggräfe, Maceler Aldrovandi, Bernhard Henkelmann, Jonas Wanninger, Eikan Mishima, Elena Lytton, David Emler, Bettina Proneth, Michael Sattler, Marcus Conrad. Phase separation of FSP1 promotes ferroptosis. Nature. 2023 Jul; 619(7969):371-377. doi: 10.1038/s41586-023-06255-6. [PMID: 37380771]
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  • Na Yang, Runbin Sun, Xiaoli Zhang, Jing Wang, Lulu Wang, Huaijun Zhu, Man Yuan, Yifan Xu, Chun Ge, Jun He, Min Wang. Alternative pathway of bile acid biosynthesis contributes to ameliorate NASH after induction of NAMPT/NAD+/SIRT1 axis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Jun; 164(?):114987. doi: 10.1016/j.biopha.2023.114987. [PMID: 37315437]
  • Jun Guo, Long Chen, Min Ma. Ginsenoside Rg1 Suppresses Ferroptosis of Renal Tubular Epithelial Cells in Sepsis-induced Acute Kidney Injury via the FSP1-CoQ10-NAD(P)H Pathway. Current medicinal chemistry. 2023 Jun; ?(?):. doi: 10.2174/0929867330666230607125054. [PMID: 37287288]
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  • Ju-Yi Hsieh, Kun-Chi Chen, Chun-Hsiung Wang, Guang-Yaw Liu, Jie-An Ye, Yu-Tung Chou, Yi-Chun Lin, Cheng-Jhe Lyu, Rui-Ying Chang, Yi-Liang Liu, Yen-Hsien Li, Mau-Rong Lee, Meng-Chiao Ho, Hui-Chih Hung. Suppression of the human malic enzyme 2 modifies energy metabolism and inhibits cellular respiration. Communications biology. 2023 May; 6(1):548. doi: 10.1038/s42003-023-04930-y. [PMID: 37217557]
  • Yanqiu Yang, Ru Chen, Yue Che, Xiaohu Yao, Mingxia Fang, Yingjie Wang, Di Zhou, Ning Li, Yue Hou. Isoamericanin A improves lipopolysaccharide-induced memory impairment in mice through suppression of the nicotinamide adenine dinucleotide phosphateoxidase-dependent nuclear factor kappa B signaling pathway. Phytotherapy research : PTR. 2023 May; ?(?):. doi: 10.1002/ptr.7858. [PMID: 37209001]
  • Lamia Sakouhi, Oumayma Kadri, Sirine Werghi, Marouane Ben Massoud, Oussama Kharbech, Yoshiyuki Murata, Abdelilah Chaoui. Seed pretreatment with melatonin confers cadmium tolerance to chickpea seedlings through cellular redox homeostasis and antioxidant gene expression improvement. Environmental science and pollution research international. 2023 May; ?(?):. doi: 10.1007/s11356-023-27562-5. [PMID: 37191750]
  • Qi Ding, Ke Wen, Qian Li, Qi-Hang Zhao, Jia-Le Zhao, Yun-Fei Xiao, Xiao-Hui Guan, Mei-Xiu Jiang, Feng Zhang, Lingfang Wang. CD38 deficiency promotes skeletal muscle and brown adipose tissue energy expenditure through activating NAD+-Sirt1-PGC1α signaling pathway. Canadian journal of physiology and pharmacology. 2023 May; ?(?):. doi: 10.1139/cjpp-2022-0454. [PMID: 37192549]
  • Jongsu Jeon, Dohyun Lee, Bobae Kim, Bo-Yoon Park, Chang Joo Oh, Min-Ji Kim, Jae-Han Jeon, In-Kyu Lee, Onyu Park, Seoyeong Baek, Chae Won Lim, Dongryeol Ryu, Sungsoon Fang, Johan Auwerx, Kyong-Tai Kim, Hoe-Yune Jung. CycloZ Improves Hyperglycemia and Lipid Metabolism by Modulating Lysine Acetylation in KK-Ay Mice. Diabetes & metabolism journal. 2023 Apr; ?(?):. doi: 10.4093/dmj.2022.0244. [PMID: 37098411]
  • Cong-Hui Yao, Joon Seok Park, Kiran Kurmi, Song-Hua Hu, Giulia Notarangelo, Joseph Crowley, Heidi Jacobson, Sheng Hui, Arlene H Sharpe, Marcia C Haigis. Uncoupled glycerol-3-phosphate shuttle in kidney cancer reveals that cytosolic GPD is essential to support lipid synthesis. Molecular cell. 2023 04; 83(8):1340-1349.e7. doi: 10.1016/j.molcel.2023.03.023. [PMID: 37084714]
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  • Xin Liu, Liwen Wang, Tsokyi Choera, Xin Fang, Gang Wang, Wenhua Chen, Yin-Won Lee, Sherif Ramzy Mohamed, Dawood H Dawood, Jianrong Shi, Jianhong Xu, Nancy P Keller. Paralogous FgIDO genes with differential roles in tryptophan catabolism, fungal development and virulence in Fusarium graminearum. Microbiological research. 2023 Apr; 272(?):127382. doi: 10.1016/j.micres.2023.127382. [PMID: 37030080]
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  • Peng Lyu, Shengrong Li, Ying Han, Shengnan Shen, Zheling Feng, Piliang Hao, Zhengqiu Li, Ligen Lin. Affinity-based protein profiling-driven discovery of myricanol as a Nampt activator. Bioorganic chemistry. 2023 04; 133(?):106435. doi: 10.1016/j.bioorg.2023.106435. [PMID: 36841049]
  • Jay Jethva, Sophie Lichtenauer, Romy Schmidt-Schippers, Anja Steffen-Heins, Gernot Poschet, Markus Wirtz, Joost T van Dongen, Jürgen Eirich, Iris Finkemeier, Wolfgang Bilger, Markus Schwarzländer, Margret Sauter. Mitochondrial alternative NADH dehydrogenases NDA1 and NDA2 promote survival of reoxygenation stress in Arabidopsis by safeguarding photosynthesis and limiting ROS generation. The New phytologist. 2023 04; 238(1):96-112. doi: 10.1111/nph.18657. [PMID: 36464787]
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  • Olga A Fedotova, Elizaveta A Polyakova, Olga I Grabelnych. Ca2+-dependent oxidation of exogenous NADH and NADPH by the mitochondria of spring wheat and its relation with AOX capacity and ROS content at high temperatures. Journal of plant physiology. 2023 Apr; 283(?):153943. doi: 10.1016/j.jplph.2023.153943. [PMID: 36841182]
  • Tasnim Arroum, Marie-Theres Borowski, Nico Marx, Frank Schmelter, Martin Scholz, Olympia Ekaterini Psathaki, Michael Hippler, José Antonio Enriquez, Karin B Busch. Loss of respiratory complex I subunit NDUFB10 affects complex I assembly and supercomplex formation. Biological chemistry. 2023 Mar; ?(?):. doi: 10.1515/hsz-2022-0309. [PMID: 36952351]
  • Chen Guo, Qingxia Huang, Yisa Wang, Yao Yao, Jing Li, Jinjin Chen, Mingxia Wu, Zepeng Zhang, Mingyao E, Hongyu Qi, Peng Ji, Qing Liu, Daqing Zhao, Hang Su, Wenxiu Qi, Xiangyan Li. Therapeutic application of natural products: NAD+ metabolism as potential target. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Mar; 114(?):154768. doi: 10.1016/j.phymed.2023.154768. [PMID: 36948143]
  • Kaiqing Ma, He Yang, Xingkang Wu, Fangjun Huo, Fangqin Cheng, Caixia Yin. An Activatable NIR Fluorescent Probe for NAD(P)H and Its Application to the Real-Time Monitoring of p53 Abnormalities In Vivo. Angewandte Chemie (International ed. in English). 2023 Mar; ?(?):e202301518. doi: 10.1002/anie.202301518. [PMID: 36867115]
  • Xiaojing Wei, Chuanfei Wei, Yutian Tan, Ximing Dong, Zhao Yang, Jianqun Yan, Xiao Luo. Both prolonged high-fat diet consumption and calorie restriction boost hepatic NAD+ metabolism in mice. The Journal of nutritional biochemistry. 2023 Feb; ?(?):109296. doi: 10.1016/j.jnutbio.2023.109296. [PMID: 36849030]
  • Lyon Bruinsma, Sebastian Wenk, Nico J Claassens, Vitor A P Martins Dos Santos. Paving the way for synthetic C1 - Metabolism in Pseudomonas putida through the reductive glycine pathway. Metabolic engineering. 2023 Feb; ?(?):. doi: 10.1016/j.ymben.2023.02.004. [PMID: 36804222]
  • Michelle T Hulin, Lionel Hill, Jonathan D G Jones, Wenbo Ma. Pangenomic analysis reveals plant NAD+ manipulation as an important virulence activity of bacterial pathogen effectors. Proceedings of the National Academy of Sciences of the United States of America. 2023 Feb; 120(7):e2217114120. doi: 10.1073/pnas.2217114120. [PMID: 36753463]
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