Cinnamoylglycine (BioDeep_00000017799)

 

Secondary id: BioDeep_00000406326

human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite


代谢物信息卡片


{[(2E)-3-phenylprop-2-enoyl]amino}acetic acid

化学式: C11H11NO3 (205.0738896)
中文名称: 肉桂酰甘氨酸, N-肉桂酰甘氨酸
谱图信息: 最多检出来源 Homo sapiens(blood) 0.64%

Reviewed

Last reviewed on 2024-09-13.

Cite this Page

Cinnamoylglycine. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/cinnamoylglycine (retrieved 2024-11-24) (BioDeep RN: BioDeep_00000017799). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1=CC=C(C=C1)C=CC(=O)NCC(=O)O
InChI: InChI=1S/C11H11NO3/c13-10(12-8-11(14)15)7-6-9-4-2-1-3-5-9/h1-7H,8H2,(H,12,13)(H,14,15)

描述信息

Cinnamoylglycine is known as a urinary metabolite in man (PMID 649712) although whether it is formed de novo from plant cinnamate or is a plant product excreted. unchanged has not been conclusively demonstrated. When cinnamoylglycine occurs naturally it is probably a food constituent excreted unchanged. It is not found when small quantities (0.5-6 g) of cinnamic acid are fed to man, but by analogy with animal experiments may be produced when much larger quantities are given. (PMID 6743769).
Cinnamoylglycine is known as a urinary metabolite in man (PMID 649712) although whether it is formed de novo from plant cinnamate or is a plant product excreted
Cinnamoylglycine is a glycine conjugate of cinnamic acid and a urinary metabolite in human. Cinnamoylglycine is used as a potential urinary biomarker indicating intact or disrupted colonization resistance during and after antibiotic treatment[1].

同义名列表

9 个代谢物同义名

{[(2E)-3-phenylprop-2-enoyl]amino}acetic acid; 2-[(2E)-3-phenylprop-2-enamido]acetic acid; [(2E)-3-phenylprop-2-enamido]acetic acid; N-(1-oxo-3-Phenyl-2-propen-1-yl)-glycine; N-(1-oxo-3-Phenyl-2-propenyl)-glycine; N-Cinnamoyl-glycine; N-Cinnamoylglycine; N-Cinnamylglycine; Cinnamoylglycine



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Vera Wewer, Helga Peisker, Katharina Gutbrod, Mazen Al-Bahra, Dirk Menche, Ngongeh Glory Amambo, Fanny F Fombad, Abdel Jelil Njouendou, Kenneth Pfarr, Samuel Wanji, Achim Hoerauf, Peter Dörmann. Urine metabolites for the identification of Onchocerca volvulus infections in patients from Cameroon. Parasites & vectors. 2021 Aug; 14(1):397. doi: 10.1186/s13071-021-04893-1. [PMID: 34380554]
  • Yan Chen, Leila R Zelnick, Matthew P Huber, Ke Wang, Nisha Bansal, Andrew N Hoofnagle, Rajan K Paranji, Susan R Heckbert, Noel S Weiss, Alan S Go, Chi-Yuan Hsu, Harold I Feldman, Sushrut S Waikar, Rupal C Mehta, Anand Srivastava, Stephen L Seliger, James P Lash, Anna C Porter, Dominic S Raj, Bryan R Kestenbaum. Association Between Kidney Clearance of Secretory Solutes and Cardiovascular Events: The Chronic Renal Insufficiency Cohort (CRIC) Study. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2021 08; 78(2):226-235.e1. doi: 10.1053/j.ajkd.2020.12.005. [PMID: 33421453]
  • Ke Wang, Leila R Zelnick, Yan Chen, Andrew N Hoofnagle, Terry Watnick, Stephen Seliger, Bryan Kestenbaum. Alterations of Proximal Tubular Secretion in Autosomal Dominant Polycystic Kidney Disease. Clinical journal of the American Society of Nephrology : CJASN. 2020 01; 15(1):80-88. doi: 10.2215/cjn.05610519. [PMID: 31628117]
  • Mark E Obrenovich, MaryAnn Tima, Alex Polinkovsky, Renliang Zhang, Steven N Emancipator, Curtis J Donskey. Targeted Metabolomics Analysis Identifies Intestinal Microbiota-Derived Urinary Biomarkers of Colonization Resistance in Antibiotic-Treated Mice. Antimicrobial agents and chemotherapy. 2017 08; 61(8):. doi: 10.1128/aac.00477-17. [PMID: 28584146]
  • Matthew B Rivara, Leila R Zelnick, Andrew N Hoofnagle, Rick Newitt, Russell P Tracy, Mario Kratz, David S Weigle, Bryan R Kestenbaum. Diurnal and Long-term Variation in Plasma Concentrations and Renal Clearances of Circulating Markers of Kidney Proximal Tubular Secretion. Clinical chemistry. 2017 04; 63(4):915-923. doi: 10.1373/clinchem.2016.260117. [PMID: 28188231]
  • Juan Zhang, Rongli Sun, Yue Chen, Kehong Tan, Haiyan Wei, Lihong Yin, Yuepu Pu. Small molecule metabolite biomarker candidates in urine from mice exposed to formaldehyde. International journal of molecular sciences. 2014 Sep; 15(9):16458-68. doi: 10.3390/ijms150916458. [PMID: 25233128]
  • Sheila Ganti, Sandra L Taylor, Omran Abu Aboud, Joy Yang, Christopher Evans, Michael V Osier, Danny C Alexander, Kyoungmi Kim, Robert H Weiss. Kidney tumor biomarkers revealed by simultaneous multiple matrix metabolomics analysis. Cancer research. 2012 Jul; 72(14):3471-9. doi: 10.1158/0008-5472.can-11-3105. [PMID: 22628425]
  • Yueying Zhen, Kristopher W Krausz, Chi Chen, Jeffrey R Idle, Frank J Gonzalez. Metabolomic and genetic analysis of biomarkers for peroxisome proliferator-activated receptor alpha expression and activation. Molecular endocrinology (Baltimore, Md.). 2007 Sep; 21(9):2136-51. doi: 10.1210/me.2007-0150. [PMID: 17550978]
  • B P Nutley, P Farmer, J Caldwell. Metabolism of trans-cinnamic acid in the rat and the mouse and its variation with dose. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 1994 Oct; 32(10):877-86. doi: 10.1016/0278-6915(94)90085-x. [PMID: 7959442]