Caspofungin (BioDeep_00000033242)

   

human metabolite blood metabolite Chemicals and Drugs


代谢物信息卡片


N-[(3S,6S,9S,11R,15S,20R,21S,24S,25S)-3-[(1R)-3-Amino-1-hydroxypropyl]-21-[(2-aminoethyl)amino]-6-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-5,8,11,17,20,23,25-heptahydroxy-15-[(1R)-1-hydroxyethyl]-2,14-dioxo-1,4,7,13,16,22-hexaazatricyclo[22.3.0.0⁹,¹³]heptacosa-4,7,16,22-tetraen-18-yl]-10,12-dimethyltetradecanimidate

化学式: C52H88N10O15 (1092.6430298)
中文名称: 卡泊芬净
谱图信息: 最多检出来源 () 0%

Reviewed

Last reviewed on 2024-10-31.

Cite this Page

Caspofungin. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/caspofungin (retrieved 2024-11-26) (BioDeep RN: BioDeep_00000033242). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: CCC(C)CC(C)CCCCCCCCC(=O)NC1CC(C(NC(=O)C2C(CCN2C(=O)C(NC(=O)C(NC(=O)C3CC(CN3C(=O)C(NC1=O)C(C)O)O)C(C(C4=CC=C(C=C4)O)O)O)C(CCN)O)O)NCCN)O
InChI: InChI=1S/C52H88N10O15/c1-5-28(2)24-29(3)12-10-8-6-7-9-11-13-39(69)56-34-26-38(68)46(55-22-21-54)60-50(75)43-37(67)19-23-61(43)52(77)41(36(66)18-20-53)58-49(74)42(45(71)44(70)31-14-16-32(64)17-15-31)59-48(73)35-25-33(65)27-62(35)51(76)40(30(4)63)57-47(34)72/h14-17,28-30,33-38,40-46,55,63-68,70-71H,5-13,18-27,53-54H2,1-4H3,(H,56,69)(H,57,72)(H,58,74)(H,59,73)(H,60,75)/t28?,29?,30-,33-,34+,35+,36-,37+,38-,40+,41+,42+,43+,44+,45+,46+/m1/s1

描述信息

Caspofungin (brand name Cancidas worldwide) is an antifungal drug, the first of a new class termed the echinocandins from Merck & Co., Inc. It shows activity against infections with Aspergillus and Candida, and works by inhibiting (1,3)-D-Glucan of the fungal cell wall. Caspofungin is administered intravenously.
J - Antiinfectives for systemic use > J02 - Antimycotics for systemic use > J02A - Antimycotics for systemic use
D000890 - Anti-Infective Agents > D000935 - Antifungal Agents > D054714 - Echinocandins
D004791 - Enzyme Inhibitors

同义名列表

9 个代谢物同义名

N-[(3S,6S,9S,11R,15S,20R,21S,24S,25S)-3-[(1R)-3-Amino-1-hydroxypropyl]-21-[(2-aminoethyl)amino]-6-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-5,8,11,17,20,23,25-heptahydroxy-15-[(1R)-1-hydroxyethyl]-2,14-dioxo-1,4,7,13,16,22-hexaazatricyclo[22.3.0.0⁹,¹³]heptacosa-4,7,16,22-tetraen-18-yl]-10,12-dimethyltetradecanimidate; N-[(3S,6S,9S,11R,15S,18S,20R,21S,24S,25S)-3-[(1R)-3-amino-1-hydroxypropyl]-21-[(2-aminoethyl)amino]-6-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-11,20,25-trihydroxy-15-[(1R)-1-hydroxyethyl]-2,5,8,14,17,23-hexaoxo-1,4,7,13,16,22-hexaazatricyclo[22.3.0.0⁹,¹³]heptacosan-18-yl]-10,12-dimethyltetradecanamide; (4R,5S)-5-((2-Aminoethyl)amino)-N2-(10,12-dimethyltetradecanoyl)-4-hydroxy-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-trans-3-hydroxy-L-proline cyclic (1->6) disulfide; Caspofungin acetate; Caspofungin MSD; Caspofungine; Capsofungin; Caspofungin; Cancidas



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Yue Du, Yundi Zhang, Zhiyan Yang, Yue Li, Xinyu Wang, Ziqiang Li, Lei Ren, Yan Li. Artificial Neural Network Analysis of Determinants of Tacrolimus Pharmacokinetics in Liver Transplant Recipients. The Annals of pharmacotherapy. 2024 May; 58(5):469-479. doi: 10.1177/10600280231190943. [PMID: 37559252]
  • Xiao-Chen Wei, Ming-Feng Zhao, Xia Xiao. Supratherapeutic posaconazole concentrations associated with hyperlipidemia in a patient with HSCT. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2024 Mar; 30(3):255-257. doi: 10.1016/j.jiac.2023.10.008. [PMID: 37832823]
  • Taylor J Schoen, Dante G Calise, Jin Woo Bok, Morgan A Giese, Chibueze D Nwagwu, Robert Zarnowski, David Andes, Anna Huttenlocher, Nancy P Keller. Aspergillus fumigatus transcription factor ZfpA regulates hyphal development and alters susceptibility to antifungals and neutrophil killing during infection. PLoS pathogens. 2023 05; 19(5):e1011152. doi: 10.1371/journal.ppat.1011152. [PMID: 37126504]
  • Ke-Zhi Chen, Lu-Ling Wang, Jin-Yan Liu, Jun-Tao Zhao, Si-Jia Huang, Ming-Jie Xiang. P4-ATPase subunit Cdc50 plays a role in yeast budding and cell wall integrity in Candida glabrata. BMC microbiology. 2023 04; 23(1):99. doi: 10.1186/s12866-023-02810-3. [PMID: 37046215]
  • Shulin Cao, Wenqiang Jiang, Yan Shu, Wei Li, Yani Zhang, Aixiang Zhang, Huaigu Chen. UDP-Galactopyranose Mutase Mediates Cell Wall Integrity, Polarity Growth, and Virulence in Fusarium graminearum. Applied and environmental microbiology. 2023 Jan; ?(?):e0123522. doi: 10.1128/aem.01235-22. [PMID: 36656025]
  • Ertan Sal, Jannik Stemler, Jon Salmanton-García, Iker Falces-Romero, László Kredics, Elisabeth Meyer, Benjamin Würstl, Cornelia Lass-Flörl, Zdenek Racil, Nikolay Klimko, Simone Cesaro, Anupma Jyoti Kindo, Hilmar Wisplinghoff, Philipp Koehler, Oliver A Cornely, Danila Seidel. Invasive Trichoderma spp. infections: clinical presentation and outcome of cases from the literature and the FungiScope® registry. The Journal of antimicrobial chemotherapy. 2022 09; 77(10):2850-2858. doi: 10.1093/jac/dkac235. [PMID: 35929089]
  • Xiaoyun Ran, Pengfei Wang, An Zhang, Binfei Tang. Efficacy and safety of caspofungin for patients with hepatic insufficiency. BMC infectious diseases. 2022 Jun; 22(1):560. doi: 10.1186/s12879-022-07527-8. [PMID: 35725403]
  • Zheng Wu, Jinhua Lan, Xipei Wang, Yijin Wu, Fen Yao, Yifan Wang, Bo-Xin Zhao, Yirong Wang, Jingchun Chen, Chunbo Chen. Population Pharmacokinetics of Caspofungin and Dose Simulations in Heart Transplant Recipients. Antimicrobial agents and chemotherapy. 2022 05; 66(5):e0224921. doi: 10.1128/aac.02249-21. [PMID: 35389237]
  • Mahzad Erami, Omid Raiesi, Mansooreh Momen-Heravi, Muhammad Ibrahim Getso, Mojtaba Fakhrehi, Narges Mehri, Mohammad Yarahmadi, Sasan Amiri, Vahid Raissi, Seyed Jamal Hashemi. Clinical impact of Candida respiratory tract colonization and acute lung infections in critically ill patients with COVID-19 pneumonia. Microbial pathogenesis. 2022 May; 166(?):105520. doi: 10.1016/j.micpath.2022.105520. [PMID: 35405278]
  • Nicolas Garbez, Litaty C Mbatchi, Steven C Wallis, Laurent Muller, Jeffrey Lipman, Jason A Roberts, Jean-Yves Lefrant, Claire Roger. Caspofungin Population Pharmacokinetic Analysis in Plasma and Peritoneal Fluid in Septic Patients with Intra-Abdominal Infections: A Prospective Cohort Study. Clinical pharmacokinetics. 2022 05; 61(5):673-686. doi: 10.1007/s40262-021-01062-6. [PMID: 34931282]
  • Robert J Tancer, Yina Wang, Siddhi Pawar, Chaoyang Xue, Gregory R Wiedman. Development of Antifungal Peptides against Cryptococcus neoformans; Leveraging Knowledge about the cdc50Δ Mutant Susceptibility for Lead Compound Development. Microbiology spectrum. 2022 04; 10(2):e0043922. doi: 10.1128/spectrum.00439-22. [PMID: 35377230]
  • Jana Marx, Vera Reinstadler, Tiziana Gasperetti, René Welte, Herbert Oberacher, Patrizia Moser, Michael Joannidis, Romuald Bellmann. Human tissue distribution of caspofungin. International journal of antimicrobial agents. 2022 Apr; 59(4):106553. doi: 10.1016/j.ijantimicag.2022.106553. [PMID: 35176477]
  • Shu-Fang Zhang, Bo-Hao Tang, An-Hua Wei, Yue Du, Zi-Wan Guan, Yan Li. Effect of drug combination on tacrolimus target dose in renal transplant patients with different CYP3A5 genotypes. Xenobiotica; the fate of foreign compounds in biological systems. 2022 Mar; 52(3):312-321. doi: 10.1080/00498254.2022.2064252. [PMID: 35395919]
  • Claire Pressiat, Nawel Ait-Ammar, Matthieu Daniel, Anne Hulin, Françoise Botterel, Eric Levesque. Pharmacokinetics/Pharmacodynamics of Caspofungin in Plasma and Peritoneal Fluid of Liver Transplant Recipients. Antimicrobial agents and chemotherapy. 2022 01; 66(1):e0118721. doi: 10.1128/aac.01187-21. [PMID: 34662185]
  • Keishi Yamasaki, Keiki Sakurama, Koji Nishi, Kenji Tsukigawa, Hakaru Seo, Masaki Otagiri, Kazuaki Taguchi. An in-vitro comparative study of the binding of caspofungin and micafungin to plasma proteins. The Journal of pharmacy and pharmacology. 2022 Jan; 74(1):88-93. doi: 10.1093/jpp/rgab157. [PMID: 34791369]
  • Siri Kurland, Elisabeth Löwdin, Mia Furebring, Ayda Shams, Erja Chryssanthou, Pernilla Lagerbäck, Thomas Tängden, Olof Breuer, Jan Sjölin. Human plasma protein levels alter the in vitro antifungal activity of caspofungin: An explanation to the effect in critically ill?. Mycoses. 2022 Jan; 65(1):79-87. doi: 10.1111/myc.13386. [PMID: 34709674]
  • Chinmay Nakhwa. Endogenous fungal endopthalmitis treated with intravitreal caspofungin in a COVID-19 recovered patient: A case report. Indian journal of ophthalmology. 2021 Dec; 69(12):3759-3761. doi: 10.4103/ijo.ijo_1192_21. [PMID: 34827041]
  • Fruzsina Nagy, Zoltán Tóth, Fanni Nyikos, Lajos Forgács, Ágnes Jakab, Andrew M Borman, László Majoros, Renátó Kovács. In vitro and in vivo interaction of caspofungin with isavuconazole against Candida auris planktonic cells and biofilms. Medical mycology. 2021 Oct; 59(10):1015-1023. doi: 10.1093/mmy/myab032. [PMID: 34021571]
  • Shay Brikman, Guy Dori, Carmel Kasher, Anna Yanovskay, Merav Strauss, Raul Colodner, Naiel Bisharat, Bibiana Chazan. Candida Bloodstream Infection, a Dire Complication in Hospitalized COVID-19 Patients: Three Cases from a Single Center in Northern Israel. The Israel Medical Association journal : IMAJ. 2021 Oct; 23(10):615-617. doi: NULL. [PMID: 34672440]
  • Farzad Pakdel, Kazem Ahmadikia, Mohammadreza Salehi, Azin Tabari, Rozita Jafari, Golfam Mehrparvar, Yasaman Rezaie, Shahin Rajaeih, Neda Alijani, Aleksandra Barac, Alireza Abdollahi, Sadegh Khodavaisy. Mucormycosis in patients with COVID-19: A cross-sectional descriptive multicentre study from Iran. Mycoses. 2021 Oct; 64(10):1238-1252. doi: 10.1111/myc.13334. [PMID: 34096653]
  • Raúl García, Kaori Itto-Nakama, José Manuel Rodríguez-Peña, Xiaolin Chen, Ana Belén Sanz, Alba de Lorenzo, Mónica Pavón-Vergés, Karen Kubo, Shinsuke Ohnuki, César Nombela, Laura Popolo, Yoshikazu Ohya, Javier Arroyo. Poacic acid, a β-1,3-glucan-binding antifungal agent, inhibits cell-wall remodeling and activates transcriptional responses regulated by the cell-wall integrity and high-osmolarity glycerol pathways in yeast. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2021 09; 35(9):e21778. doi: 10.1096/fj.202100278r. [PMID: 34383971]
  • Jean-Herlé Raphalen, Ambroise Marçais, Perrine Parize, Benoit Pilmis, Agnès Lillo-Lelouet, Lionel Lamhaut, Frédéric J Baud. Is caspofungin efficient to treat invasive candidiasis requiring continuous veno-venous hemofiltration? A case report. Therapie. 2021 Sep; 76(5):512-515. doi: 10.1016/j.therap.2020.12.013. [PMID: 33423788]
  • M Ángeles Curto, Estefanía Butassi, Juan C Ribas, Laura A Svetaz, Juan C G Cortés. Natural products targeting the synthesis of β(1,3)-D-glucan and chitin of the fungal cell wall. Existing drugs and recent findings. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2021 Jul; 88(?):153556. doi: 10.1016/j.phymed.2021.153556. [PMID: 33958276]
  • Ali Amanati, Parisa Badiee, Hadis Jafarian, Fatemeh Ghasemi, Samane Nematolahi, Sezaneh Haghpanah, Seyedeh Sedigheh Hamzavi. Impact of antifungal stewardship interventions on the susceptibility of colonized Candida species in pediatric patients with malignancy. Scientific reports. 2021 07; 11(1):14099. doi: 10.1038/s41598-021-93421-3. [PMID: 34238976]
  • Fangyi Li, Minggen Zhou, Zheng Jiao, Zijun Zou, Erqian Yu, Zhijie He. Caspofungin pharmacokinetics and probability of target attainment in ICU patients in China. Journal of global antimicrobial resistance. 2021 06; 25(?):238-263. doi: 10.1016/j.jgar.2021.03.011. [PMID: 33845162]
  • Iching G Yu, Sean E O'Brien, David M Ryckman. Pharmacokinetic and Pharmacodynamic Comparison of Intravenous and Inhaled Caspofungin. Journal of aerosol medicine and pulmonary drug delivery. 2021 06; 34(3):197-203. doi: 10.1089/jamp.2020.1645. [PMID: 32985935]
  • Frederic J Baud, Vincent Jullien, Philippe-Henri Secrétan, Pascal Houzé, Lionel Lamhaut. Are we correctly treating invasive candidiasis under continuous renal replacement therapy with echinocandins? Preliminary in vitro assessment. Anaesthesia, critical care & pain medicine. 2021 02; 40(1):100640. doi: 10.1016/j.accpm.2020.01.007. [PMID: 32251833]
  • Jéssica Tauany Andrade, William Gustavo Lima, Jaqueline França Sousa, Aline Aparecida Saldanha, Nívea Pereira De Sá, Fernanda Barbara Morais, Mayra Karla Prates Silva, Gustavo Henrique Ribeiro Viana, Susana Johann, Adriana Cristina Soares, Leonardo Allan Araújo, Simone Odília Antunes Fernandes, Valbert Nascimento Cardoso, Jaqueline Maria Siqueira Ferreira. Design, synthesis, and biodistribution studies of new analogues of marine alkaloids: Potent in vitro and in vivo fungicidal agents against Candida spp. European journal of medicinal chemistry. 2021 Jan; 210(?):113048. doi: 10.1016/j.ejmech.2020.113048. [PMID: 33316690]
  • James M Apgar, Robert R Wilkening, Dann L Parker, Dongfang Meng, Kenneth J Wildonger, Donald Sperbeck, Mark L Greenlee, James M Balkovec, Amy M Flattery, George K Abruzzo, Andrew M Galgoci, Robert A Giacobbe, Charles J Gill, Ming-Jo Hsu, Paul Liberator, Andrew S Misura, Mary Motyl, Jennifer Nielsen Kahn, Maryann Powles, Fred Racine, Jasminka Dragovic, Weiming Fan, Robin Kirwan, Shu Lee, Hao Liu, Ahmed Mamai, Kingsley Nelson, Michael Peel. Ibrexafungerp: An orally active β-1,3-glucan synthesis inhibitor. Bioorganic & medicinal chemistry letters. 2021 01; 32(?):127661. doi: 10.1016/j.bmcl.2020.127661. [PMID: 33160023]
  • Francesca Gioia, Alicia Gomez-Lopez, Maria Elena Alvarez, Elia Gomez-García de la Pedrosa, Pilar Martín-Davila, Manuel Cuenca-Estrella, Santiago Moreno, Jesús Fortun. Pharmacokinetics of echinocandins in suspected candida peritonitis: A potential risk for resistance. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2020 Dec; 101(?):24-28. doi: 10.1016/j.ijid.2020.09.019. [PMID: 32937195]
  • Sébastien Bailly, Elodie Gautier-Veyret, Minh P Lê, Lila Bouadma, Olivier Andremont, Mathilde Neuville, Bruno Mourvillier, Romain Sonneville, Eric Magalhaes, Jordane Lebut, Aguila Radjou, Roland Smonig, Michel Wolff, Laurent Massias, Claire Dupuis, Jean-François Timsit. Impact of Loading Dose of Caspofungin in Pharmacokinetic-Pharmacodynamic Target Attainment for Severe Candidiasis Infections in Patients in Intensive Care Units: the CASPOLOAD Study. Antimicrobial agents and chemotherapy. 2020 11; 64(12):. doi: 10.1128/aac.01545-20. [PMID: 32958709]
  • Ying Wang, Siegfried Hekimi. Micellization of coenzyme Q by the fungicide caspofungin allows for safe intravenous administration to reach extreme supraphysiological concentrations. Redox biology. 2020 09; 36(?):101680. doi: 10.1016/j.redox.2020.101680. [PMID: 32810741]
  • C Adembri, G Villa, E Rosi, L Tofani, S Fallani, A R De Gaudio, A Novelli. Caspofungin PK in critically ill patients after the first and fourth doses: suggestions for therapeutic drug monitoring?. Journal of chemotherapy (Florence, Italy). 2020 May; 32(3):124-131. doi: 10.1080/1120009x.2020.1737783. [PMID: 32202224]
  • Nathan P Wiederhold, Laura K Najvar, Rosie Jaramillo, Marcos Olivo, Hoja Patterson, April Connell, Yoshiko Fukuda, Junichi Mitsuyama, Gabriel Catano, Thomas F Patterson. The Novel Arylamidine T-2307 Demonstrates In Vitro and In Vivo Activity against Candida auris. Antimicrobial agents and chemotherapy. 2020 02; 64(3):. doi: 10.1128/aac.02198-19. [PMID: 31844006]
  • Qianting Yang, Tao Zhang, Dan Zhao, Ying Zhang, Yuzhu Dong, Dan Sun, Qian Du, Jing Zheng, Haidong Lu, Yalin Dong. Factors influencing caspofungin plasma concentrations in kidney transplant patients with high incidence of invasive fungal infections. Journal of clinical pharmacy and therapeutics. 2020 Feb; 45(1):72-80. doi: 10.1111/jcpt.13026. [PMID: 31468555]
  • Fan Jin, Xiao-Hang Liu, Wen-Can Chen, Zhang-Ling Fan, Huan-Ling Wang. High initial (1, 3) Beta-d-Glucan concentration may be a predictor of satisfactory response of c aspofungin combined with TMP/SMZ for HIV-negative patients with moderate to severe Pneumocystis jirovecii pneumonia. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2019 Nov; 88(?):141-148. doi: 10.1016/j.ijid.2019.08.015. [PMID: 31442630]
  • Qi Han, Chaoying Pan, Yueqing Wang, Na Wang, Yue Wang, Jianli Sang. The PP2A regulatory subunits, Cdc55 and Rts1, play distinct roles in Candida albicans' growth, morphogenesis, and virulence. Fungal genetics and biology : FG & B. 2019 10; 131(?):103240. doi: 10.1016/j.fgb.2019.103240. [PMID: 31185286]
  • Yuhei Shibata, Yuri Miyahara, Yuna Sadaka, Mika Yasue, Minami Fujimura, Midori Soda, Miho Yamamoto, Hiroko Kato, Akio Suzuki, Katsura Tsukamoto, Takeshi Hara, Hisashi Tsurumi, Kiyoyuki Kitaichi. Evaluation of the effectiveness of caspofungin against febrile neutropenia and the factors related to the alteration in its plasma concentration. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2019 Oct; 25(10):801-805. doi: 10.1016/j.jiac.2019.04.011. [PMID: 31047782]
  • Deepak Kumar Choudhary, Priyanka Bhakt, Rupinder Kaur. Essential Role for the Phosphatidylinositol 3,5-Bisphosphate Synthesis Complex in Caspofungin Tolerance and Virulence in Candida glabrata. Antimicrobial agents and chemotherapy. 2019 08; 63(8):. doi: 10.1128/aac.00886-19. [PMID: 31138567]
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  • S Kurland, M Furebring, E Löwdin, E Eliasson, E I Nielsen, J Sjölin. Pharmacokinetics of Caspofungin in Critically Ill Patients in Relation to Liver Dysfunction: Differential Impact of Plasma Albumin and Bilirubin Levels. Antimicrobial agents and chemotherapy. 2019 06; 63(6):. doi: 10.1128/aac.02466-18. [PMID: 30962329]
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  • Nathan P Wiederhold, Shawn R Lockhart, Laura K Najvar, Elizabeth L Berkow, Rosie Jaramillo, Marcos Olivo, Edward P Garvey, Christopher M Yates, Robert J Schotzinger, Gabriel Catano, Thomas F Patterson. The Fungal Cyp51-Specific Inhibitor VT-1598 Demonstrates In Vitro and In Vivo Activity against Candida auris. Antimicrobial agents and chemotherapy. 2019 03; 63(3):. doi: 10.1128/aac.02233-18. [PMID: 30530603]
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  • Senaid Trnacevic, Amer Mujkanovic, Edin Nislic, Edin Begic, Zenaida Karasalihovic, Adnan Cickusic, Alma Trnacevic, Mirna Aleckovic Halilovic. Invasive Aspergillosis After Kidney Transplant-Treatment Approach. Medical archives (Sarajevo, Bosnia and Herzegovina). 2018 Dec; 72(6):456-458. doi: 10.5455/medarh.2018.72.456-458. [PMID: 30814781]
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