chloral hydrate (BioDeep_00001867623)
Main id: BioDeep_00000006376
代谢物信息卡片
chloral hydrate
化学式: C2H3Cl3O2 (163.91986280000003)
中文名称: 三氯乙醛水合物
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(C(Cl)(Cl)Cl)(O)O
InChI: InChI=1S/C2H3Cl3O2/c3-2(4,5)1(6)7/h1,6-7H
描述信息
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives
N - Nervous system > N05 - Psycholeptics > N05C - Hypnotics and sedatives > N05CC - Aldehydes and derivatives
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2199 - Adjuvant Analgesic
An organochlorine compound that is the hydrate of trichloroacetaldehyde.
同义名列表
1 个代谢物同义名
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:28142
- KEGG: C06899
- KEGGdrug: D00265
- PubChem: 2707
- DrugBank: DB01563
- ChEMBL: CHEMBL455917
- MeSH: Chloral Hydrate
- CAS: 302-17-0
- MetaboLights: MTBLC28142
- PubChem: 9116
- NIKKAJI: J1.517B
- RefMet: Chloral hydrate
分类词条
相关代谢途径
Reactome(0)
BioCyc(3)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jinfeng Zhao, Shiyu Yan, Xue Ma, Yanqing Song, Yao Pan. Nrf2 regulates the activation of THP-1 cells induced by chloral hydrate.
Ecotoxicology and environmental safety.
2023 Mar; 256(?):114841. doi:
10.1016/j.ecoenv.2023.114841. [PMID: 36989555] - Ling Du, Yanmei Liu, Zhineng Hao, Miao Chen, Liping Li, Dong Ren, Junjian Wang. Fertilization regime shifts the molecular diversity and chlorine reactivity of soil dissolved organic matter from tropical croplands.
Water research.
2022 Oct; 225(?):119106. doi:
10.1016/j.watres.2022.119106. [PMID: 36152442] - Amanda J Stolarz, Bijay P Chhetri, Michael J Borrelli, Samir V Jenkins, Azemat Jamshidi-Parsian, Joshua H Phillips, Daniel Fologea, Jay Gandy, Robert J Griffin. Liposome Formulation for Tumor-Targeted Drug Delivery Using Radiation Therapy.
International journal of molecular sciences.
2022 Oct; 23(19):. doi:
10.3390/ijms231911662. [PMID: 36232973] - Yixuan Feng, Tai Wang, Lingtong Liu. An Efficient Clearing Protocol for the Study of Seed Development in Tomato (Solanum lycopersicum L.).
Journal of visualized experiments : JoVE.
2022 09; ?(187):. doi:
10.3791/64445. [PMID: 36155423] - Fa-Zhi Su, Chen-Xi Bai, Wen-Sen Zhang, Jing Yang, Jian-Ping Hu, Yan-Ping Sun, Bing-You Yang, Hai-Xue Kuang, Qiu-Hong Wang. [Study on drug properties of Arisaematis Rhizoma and Arisaema Cum Bile based on substance and energy metabolism in normal and cold/heat syndrome model rats].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2022 Sep; 47(17):4682-4690. doi:
10.19540/j.cnki.cjcmm.20220524.402. [PMID: 36164875] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Yang Lv, Hongyu Liang, Jun Li, Xiuxiu Li, Xiaohui Tang, Songyu Gao, Hao Zou, Jing Zhang, Mei Wang, Liang Xiao. Central inhibition prevents the in vivo acute toxicity of harmine in mice.
The Journal of toxicological sciences.
2021; 46(6):289-301. doi:
10.2131/jts.46.289. [PMID: 34078836] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Hirotaka Sato, Yuki Ito, Miho Inoue, Yuki Nakahira, Satoru Hashimoto, Tamie Nakajima, Michihiro Kamijima. Simple method to detect triclofos and its metabolites in plasma of children by combined use of liquid chromatography tandem-mass spectrometry and gas chromatography-mass spectrometry.
Scientific reports.
2019 06; 9(1):9294. doi:
10.1038/s41598-019-45790-z. [PMID: 31243319] - D Cao, Y Liu, J Li, J Gong. Isoflurane: An Ideal Anesthetic for Rodent Orthotopic Liver Transplantation Surgery?.
Transplantation proceedings.
2016 Oct; 48(8):2815-2820. doi:
10.1016/j.transproceed.2016.06.057. [PMID: 27788823] - Gonzalo H Villarino, Qiwen Hu, Silvia Manrique, Miguel Flores-Vergara, Bhupinder Sehra, Linda Robles, Javier Brumos, Anna N Stepanova, Lucia Colombo, Eva Sundberg, Steffen Heber, Robert G Franks. Transcriptomic Signature of the SHATTERPROOF2 Expression Domain Reveals the Meristematic Nature of Arabidopsis Gynoecial Medial Domain.
Plant physiology.
2016 05; 171(1):42-61. doi:
10.1104/pp.15.01845. [PMID: 26983993] - Robert G Franks. Histological Analysis of the Arabidopsis Gynoecium and Ovules Using Chloral Hydrate Clearing and Differential Interference Contrast Light Microscopy.
Methods in molecular biology (Clifton, N.J.).
2016; 1457(?):1-7. doi:
10.1007/978-1-4939-3795-0_1. [PMID: 27557569] - Jie Gao, Caixia Yang, Hui Ding, Yanli Zhang, Jinhua Xue, Yanning Cai. 2,2,2-Trichloroethanol lengthens the circadian period of Bmal1-driven circadian bioluminescence rhythms in U2OS cells.
Biochemical and biophysical research communications.
2015 Jul; 462(3):239-44. doi:
10.1016/j.bbrc.2015.04.123. [PMID: 25956065] - Albert L Shroads, Bonnie S Coats, Taimour Langaee, Jonathan J Shuster, Peter W Stacpoole. Chloral hydrate, through biotransformation to dichloroacetate, inhibits maleylacetoacetate isomerase and tyrosine catabolism in humans.
Drug metabolism and personalized therapy.
2015 Mar; 30(1):49-55. doi:
10.1515/dmdi-2014-0015. [PMID: 25283137] - Yongchao Zhao, Jianping He, Xiaoxiao Han, Xiulin Tian, Mingyu Deng, Weiping Chen, Bo Jiang. Modification of hydroxypropyl guar gum with ethanolamine.
Carbohydrate polymers.
2012 Oct; 90(2):988-92. doi:
10.1016/j.carbpol.2012.06.032. [PMID: 22840030] - Ramesh R Kaini, Laurel O Sillerud, Siqin Zhaorigetu, Chien-An A Hu. Autophagy regulates lipolysis and cell survival through lipid droplet degradation in androgen-sensitive prostate cancer cells.
The Prostate.
2012 Sep; 72(13):1412-22. doi:
10.1002/pros.22489. [PMID: 22294520] - Gale B Carey, Lisa C Merrill. Meal-feeding rodents and toxicology research.
Chemical research in toxicology.
2012 Aug; 25(8):1545-50. doi:
10.1021/tx300109x. [PMID: 22642213] - Rachel M Squillace, David Miller, Scott D Wardwell, Frank Wang, Tim Clackson, Victor M Rivera. Synergistic activity of the mTOR inhibitor ridaforolimus and the antiandrogen bicalutamide in prostate cancer models.
International journal of oncology.
2012 Aug; 41(2):425-32. doi:
10.3892/ijo.2012.1487. [PMID: 22614157] - Sona Krizkova, Marketa Ryvolova, David Hynek, Tomas Eckschlager, Petr Hodek, Michal Masarik, Vojtech Adam, Rene Kizek. Immunoextraction of zinc proteins from human plasma using chicken yolk antibodies immobilized onto paramagnetic particles and their electrophoretic analysis.
Electrophoresis.
2012 Jul; 33(12):1824-32. doi:
10.1002/elps.201100638. [PMID: 22674189] - Alessandro de Souza Prestes, Sílvio Terra Stefanello, Syed M Salman, Andréia Martini Pazini, Ricardo S Schwab, Antônio Luiz Braga, Nilda Berenice de Vargas Barbosa, João B T Rocha. Antioxidant activity of β-selenoamines and their capacity to mimic different enzymes.
Molecular and cellular biochemistry.
2012 Jun; 365(1-2):85-92. doi:
10.1007/s11010-012-1246-6. [PMID: 22311601] - Christian Thomas, Latif A Wafa, Francois Lamoureux, Helen Cheng, Ladan Fazli, Martin E Gleave, Paul S Rennie. Carbidopa enhances antitumoral activity of bicalutamide on the androgen receptor-axis in castration-resistant prostate tumors.
The Prostate.
2012 Jun; 72(8):875-85. doi:
10.1002/pros.21490. [PMID: 22072572] - Giovanni Leonardi, Marie Vahter, Felicity Clemens, Walter Goessler, Eugen Gurzau, Kari Hemminki, Rupert Hough, Kvetoslava Koppova, Rajiv Kumar, Peter Rudnai, Simona Surdu, Tony Fletcher. Inorganic arsenic and basal cell carcinoma in areas of Hungary, Romania, and Slovakia: a case-control study.
Environmental health perspectives.
2012 May; 120(5):721-6. doi:
10.1289/ehp.1103534. [PMID: 22436128] - Tiina Karonen, Jouko Laitila, Mikko Niemi, Pertti J Neuvonen, Janne T Backman. Fluconazole but not the CYP3A4 inhibitor, itraconazole, increases zafirlukast plasma concentrations.
European journal of clinical pharmacology.
2012 May; 68(5):681-8. doi:
10.1007/s00228-011-1158-5. [PMID: 22108774] - Hao L Tang, Yen-Chih Chen, John M Regan, Yuefeng F Xie. Disinfection by-product formation potentials in wastewater effluents and their reductions in a wastewater treatment plant.
Journal of environmental monitoring : JEM.
2012 May; 14(6):1515-22. doi:
10.1039/c2em00015f. [PMID: 22596061] - Juliet Richards, Ai Chiin Lim, Colin W Hay, Angela E Taylor, Anna Wingate, Karolina Nowakowska, Carmel Pezaro, Suzanne Carreira, Jane Goodall, Wiebke Arlt, Iain J McEwan, Johann S de Bono, Gerhardt Attard. Interactions of abiraterone, eplerenone, and prednisolone with wild-type and mutant androgen receptor: a rationale for increasing abiraterone exposure or combining with MDV3100.
Cancer research.
2012 May; 72(9):2176-82. doi:
10.1158/0008-5472.can-11-3980. [PMID: 22411952] - Hong Can Zhu, Jing Zhao, Chang Yue Luo, Qian Qian Li. Gastrointestinal dysfunction in a Parkinson's disease rat model and the changes of dopaminergic, nitric oxidergic, and cholinergic neurotransmitters in myenteric plexus.
Journal of molecular neuroscience : MN.
2012 May; 47(1):15-25. doi:
10.1007/s12031-011-9560-0. [PMID: 21647710] - Emanuela Esposito, Barbara Rinaldi, Emanuela Mazzon, Maria Donniacuo, Daniela Impellizzeri, Irene Paterniti, Annalisa Capuano, Placido Bramanti, Salvatore Cuzzocrea. Anti-inflammatory effect of simvastatin in an experimental model of spinal cord trauma: involvement of PPAR-α.
Journal of neuroinflammation.
2012 Apr; 9(?):81. doi:
10.1186/1742-2094-9-81. [PMID: 22537532] - C Salvador, J Planas, C Raventós, J Ropero, J Placer, M A López, J Morote. [Impact of androgen deprivation on the lipid profile and atherogenic risk in prostate cancer patients].
Actas urologicas espanolas.
2012 Apr; 36(4):205-9. doi:
10.1016/j.acuro.2011.09.006. [PMID: 22178349] - Nicola J Clegg, John Wongvipat, James D Joseph, Chris Tran, Samedy Ouk, Anna Dilhas, Yu Chen, Kate Grillot, Eric D Bischoff, Ling Cai, Anna Aparicio, Steven Dorow, Vivek Arora, Gang Shao, Jing Qian, Hong Zhao, Guangbin Yang, Chunyan Cao, John Sensintaffar, Teresa Wasielewska, Mark R Herbert, Celine Bonnefous, Beatrice Darimont, Howard I Scher, Peter Smith-Jones, Mark Klang, Nicholas D Smith, Elisa De Stanchina, Nian Wu, Ouathek Ouerfelli, Peter J Rix, Richard A Heyman, Michael E Jung, Charles L Sawyers, Jeffrey H Hager. ARN-509: a novel antiandrogen for prostate cancer treatment.
Cancer research.
2012 Mar; 72(6):1494-503. doi:
10.1158/0008-5472.can-11-3948. [PMID: 22266222] - Ana Bárbara Dias Pereira, Talisson Machado Veríssimo, Mariana Assíria de Oliveira, Ivaldo Antônio de Araujo, Ricardo José Alves, Fernão Castro Braga. Development and validation of an HPLC-DAD method for quantification of bornesitol in extracts from Hancornia speciosa leaves after derivatization with p-toluenesulfonyl chloride.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2012 Mar; 887-888(?):133-7. doi:
10.1016/j.jchromb.2012.01.009. [PMID: 22333437] - Anisuzzaman, M Khyrul Islam, M Abdul Alim, Takeharu Miyoshi, Takeshi Hatta, Kayoko Yamaji, Yasunobu Matsumoto, Kozo Fujisaki, Naotoshi Tsuji. Longistatin is an unconventional serine protease and induces protective immunity against tick infestation.
Molecular and biochemical parasitology.
2012 Mar; 182(1-2):45-53. doi:
10.1016/j.molbiopara.2011.12.002. [PMID: 22206819] - Jun Yan, Bingxian Xie, Jillian L Capodice, Aaron E Katz. Zyflamend inhibits the expression and function of androgen receptor and acts synergistically with bicalutimide to inhibit prostate cancer cell growth.
The Prostate.
2012 Feb; 72(3):244-52. doi:
10.1002/pros.21426. [PMID: 21656835] - Marina Quartu, Maria P Serra, Marianna Boi, Giuliano Pillolla, Tiziana Melis, Laura Poddighe, Marina Del Fiacco, Danilo Falconieri, Gianfranca Carta, Elisabetta Murru, Lina Cordeddu, Antonio Piras, Maria Collu, Sebastiano Banni. Effect of acute administration of Pistacia lentiscus L. essential oil on rat cerebral cortex following transient bilateral common carotid artery occlusion.
Lipids in health and disease.
2012 Jan; 11(?):8. doi:
10.1186/1476-511x-11-8. [PMID: 22239952] - Qing Miao, Jing-Ge Li, Shan Miao, Nan Hu, Jin Zhang, Song Zhang, Yan-Hua Xie, Jian-Bo Wang, Si-Wang Wang. The bone-protective effect of genistein in the animal model of bilateral ovariectomy: roles of phytoestrogens and PTH/PTHR1 against post-menopausal osteoporosis.
International journal of molecular sciences.
2012; 13(1):56-70. doi:
10.3390/ijms13010056. [PMID: 22312238] - Ding-Bang Chen, Li Feng, Xiao-Pu Lin, Wei Zhang, Fu-Rong Li, Xiu-Ling Liang, Xun-Hua Li. Penicillamine increases free copper and enhances oxidative stress in the brain of toxic milk mice.
PloS one.
2012; 7(5):e37709. doi:
10.1371/journal.pone.0037709. [PMID: 22629446] - Boris Filipović, Ivica Matak, Lidija Bach-Rojecky, Zdravko Lacković. Central action of peripherally applied botulinum toxin type A on pain and dural protein extravasation in rat model of trigeminal neuropathy.
PloS one.
2012; 7(1):e29803. doi:
10.1371/journal.pone.0029803. [PMID: 22238656] - Juan M Debernardi, Ramiro E Rodriguez, Martin A Mecchia, Javier F Palatnik. Functional specialization of the plant miR396 regulatory network through distinct microRNA-target interactions.
PLoS genetics.
2012 Jan; 8(1):e1002419. doi:
10.1371/journal.pgen.1002419. [PMID: 22242012] - Pilar Galindo, Isabel Rodriguez-Gómez, Susana González-Manzano, Montserrat Dueñas, Rosario Jiménez, Carmen Menéndez, Félix Vargas, Juan Tamargo, Celestino Santos-Buelga, Francisco Pérez-Vizcaíno, Juan Duarte. Glucuronidated quercetin lowers blood pressure in spontaneously hypertensive rats via deconjugation.
PloS one.
2012; 7(3):e32673. doi:
10.1371/journal.pone.0032673. [PMID: 22427863] - Mongi Saoudi, Abdelfattah El Feki. Protective Role of Ficus carica Stem Extract against Hepatic Oxidative Damage Induced by Methanol in Male Wistar Rats.
Evidence-based complementary and alternative medicine : eCAM.
2012; 2012(?):150458. doi:
10.1155/2012/150458. [PMID: 22203864] - Sergio A Rosales-Corral, Gabriela Lopez-Armas, Jose Cruz-Ramos, Valery G Melnikov, Dun-Xian Tan, Lucien C Manchester, Ruben Munoz, Russel J Reiter. Alterations in Lipid Levels of Mitochondrial Membranes Induced by Amyloid-β: A Protective Role of Melatonin.
International journal of Alzheimer's disease.
2012; 2012(?):459806. doi:
10.1155/2012/459806. [PMID: 22666620] - Shiwei Bai, Jie Liu, Cheng Chang, Ling Zhang, Takaki Maekawa, Qiuyun Wang, Wenkai Xiao, Yule Liu, Jijie Chai, Frank L W Takken, Paul Schulze-Lefert, Qian-Hua Shen. Structure-function analysis of barley NLR immune receptor MLA10 reveals its cell compartment specific activity in cell death and disease resistance.
PLoS pathogens.
2012; 8(6):e1002752. doi:
10.1371/journal.ppat.1002752. [PMID: 22685408] - Tinghui Yin, Ping Wang, Rongqin Zheng, Bowen Zheng, Du Cheng, Xinling Zhang, Xintao Shuai. Nanobubbles for enhanced ultrasound imaging of tumors.
International journal of nanomedicine.
2012; 7(?):895-904. doi:
10.2147/ijn.s28830. [PMID: 22393289] - Yi-Ching Lo, Yu-Tzu Shih, Yu-Ting Tseng, Hung-Te Hsu. Neuroprotective Effects of San-Huang-Xie-Xin-Tang in the MPP(+)/MPTP Models of Parkinson's Disease In Vitro and In Vivo.
Evidence-based complementary and alternative medicine : eCAM.
2012; 2012(?):501032. doi:
10.1155/2012/501032. [PMID: 22474505] - Cheol-Min Yoo, Li Quan, Elison B Blancaflor. Divergence and Redundancy in CSLD2 and CSLD3 Function During Arabidopsis Thaliana Root Hair and Female Gametophyte Development.
Frontiers in plant science.
2012; 3(?):111. doi:
10.3389/fpls.2012.00111. [PMID: 22661983] - Xu Tao, Peng Jing-Bo, Zhang Wen-Tong, Zhao Xin, Zhang Tao-Tao, Yang Shi-Jun, Fang Lei, Zou Zhong-Mei, Cai Da-Yong. Antiatherogenic and Anti-Ischemic Properties of Traditional Chinese Medicine Xinkeshu via Endothelial Protecting Function.
Evidence-based complementary and alternative medicine : eCAM.
2012; 2012(?):302137. doi:
10.1155/2012/302137. [PMID: 22007259] - Hiromasa Saitoh, Shizuko Fujisawa, Chikako Mitsuoka, Akiko Ito, Akiko Hirabuchi, Kyoko Ikeda, Hiroki Irieda, Kae Yoshino, Kentaro Yoshida, Hideo Matsumura, Yukio Tosa, Joe Win, Sophien Kamoun, Yoshitaka Takano, Ryohei Terauchi. Large-scale gene disruption in Magnaporthe oryzae identifies MC69, a secreted protein required for infection by monocot and dicot fungal pathogens.
PLoS pathogens.
2012; 8(5):e1002711. doi:
10.1371/journal.ppat.1002711. [PMID: 22589729] - Fukun Jiang, Mei Guo, Fang Yang, Keith Duncan, David Jackson, Antoni Rafalski, Shoucai Wang, Bailin Li. Mutations in an AP2 transcription factor-like gene affect internode length and leaf shape in maize.
PloS one.
2012; 7(5):e37040. doi:
10.1371/journal.pone.0037040. [PMID: 22649507] - Xiaohong Xu, Haijuan Xiao, Jiangpei Zhao, Tongfeng Zhao. Cardioprotective effect of sodium ferulate in diabetic rats.
International journal of medical sciences.
2012; 9(4):291-300. doi:
10.7150/ijms.4298. [PMID: 22701336] - Yafei Cai, Jun Li, Shiyong Yang, Ping Li, Xuan Zhang, Honglin Liu. CIBZ, a novel BTB domain-containing protein, is involved in mouse spinal cord injury via mitochondrial pathway independent of p53 gene.
PloS one.
2012; 7(3):e33156. doi:
10.1371/journal.pone.0033156. [PMID: 22427977] - Shinichi Yamashita, Kuo-Pao Lai, Kun-Lung Chuang, Defeng Xu, Hiroshi Miyamoto, Tatsuo Tochigi, See-Tong Pang, Lei Li, Yoichi Arai, Hsing-Jien Kung, Shuyuan Yeh, Chawnshang Chang. ASC-J9 suppresses castration-resistant prostate cancer growth through degradation of full-length and splice variant androgen receptors.
Neoplasia (New York, N.Y.).
2012 Jan; 14(1):74-83. doi:
10.1593/neo.111436. [PMID: 22355276] - Chung-Hsiang Liu, Yi-Wen Lin, Nou-Ying Tang, Hsu-Jan Liu, Ching-Liang Hsieh. Neuroprotective Effect of Uncaria rhynchophylla in Kainic Acid-Induced Epileptic Seizures by Modulating Hippocampal Mossy Fiber Sprouting, Neuron Survival, Astrocyte Proliferation, and S100B Expression.
Evidence-based complementary and alternative medicine : eCAM.
2012; 2012(?):194790. doi:
10.1155/2012/194790. [PMID: 21837247] - Yumei Qi, Huijuan Xiao, Changjie Xu, Xiaojian Tian, Hui Wu, Wei Shen. Cyprinus carpio Decoction Improves Nutrition and Immunity and Reduces Proteinuria through Nephrin and CD2AP Expressions in Rats with Adriamycin-Induced Nephropathy.
Evidence-based complementary and alternative medicine : eCAM.
2012; 2012(?):237482. doi:
10.1155/2012/237482. [PMID: 22675377] - Changsong Wang, Jinghui Shi, Bo Sun, Desheng Liu, Peng Li, Yulei Gong, Ying He, Shujuan Liu, Guowang Xu, Jianyi Li, Ailin Luo, Enyou Li. Breath pentane as a potential biomarker for survival in hepatic ischemia and reperfusion injury--a pilot study.
PloS one.
2012; 7(9):e44940. doi:
10.1371/journal.pone.0044940. [PMID: 22984587] - H-M Lu, M Ye. The relative bioavailability study and fasting and fed states pharmacokinetics of bicalutamide 50-mg tablets in healthy Chinese volunteers.
Arzneimittel-Forschung.
2012 Jan; 62(1):18-21. doi:
10.1055/s-0031-1295429. [PMID: 22331758] - Sonja Janmaat, Yvette Akwa, Mohamed Doulazmi, Joëlle Bakouche, Vanessa Gautheron, Philippe Liere, Bernard Eychenne, Antoine Pianos, Paul Luiten, Ton Groothuis, Etienne-Emile Baulieu, Jean Mariani, Rachel M Sherrard, Florence Frédéric. Age-related Purkinje cell death is steroid dependent: RORα haplo-insufficiency impairs plasma and cerebellar steroids and Purkinje cell survival.
Age (Dordrecht, Netherlands).
2011 Dec; 33(4):565-78. doi:
10.1007/s11357-010-9203-3. [PMID: 21222044] - Iciar Gárate, Borja García-Bueno, José L M Madrigal, Lidia Bravo, Esther Berrocoso, Javier R Caso, Juan A Micó, Juan C Leza. Origin and consequences of brain Toll-like receptor 4 pathway stimulation in an experimental model of depression.
Journal of neuroinflammation.
2011 Nov; 8(?):151. doi:
10.1186/1742-2094-8-151. [PMID: 22053929] - Patrizia Brunetti, Letizia Zanella, Alessandra Proia, Angelo De Paolis, Giuseppina Falasca, Maria Maddalena Altamura, Luigi Sanità di Toppi, Paolo Costantino, Maura Cardarelli. Cadmium tolerance and phytochelatin content of Arabidopsis seedlings over-expressing the phytochelatin synthase gene AtPCS1.
Journal of experimental botany.
2011 Nov; 62(15):5509-19. doi:
10.1093/jxb/err228. [PMID: 21841172] - Daisuke Tamaoki, Ichirou Karahara, Takumi Nishiuchi, Tatsuya Wakasugi, Kyoji Yamada, Seiichiro Kamisaka. Involvement of auxin dynamics in hypergravity-induced promotion of lignin-related gene expression in Arabidopsis inflorescence stems.
Journal of experimental botany.
2011 Nov; 62(15):5463-9. doi:
10.1093/jxb/err224. [PMID: 21841171] - Shifeng Zhu, Rae-Dong Jeong, Srivathsa C Venugopal, Ludmila Lapchyk, DuRoy Navarre, Aardra Kachroo, Pradeep Kachroo. SAG101 forms a ternary complex with EDS1 and PAD4 and is required for resistance signaling against turnip crinkle virus.
PLoS pathogens.
2011 Nov; 7(11):e1002318. doi:
10.1371/journal.ppat.1002318. [PMID: 22072959] - Chiara Fuccio, Riccardo Schiavina, Paolo Castellucci, Domenico Rubello, Giuseppe Martorana, Monica Celli, Claudio Malizia, Marta Barios Profitos, Maria Cristina Marzola, Vincenzina Pettinato, Stefano Fanti. Androgen deprivation therapy influences the uptake of 11C-choline in patients with recurrent prostate cancer: the preliminary results of a sequential PET/CT study.
European journal of nuclear medicine and molecular imaging.
2011 Nov; 38(11):1985-9. doi:
10.1007/s00259-011-1867-0. [PMID: 21732105] - Sun Mi Park, Jin Hee Shin, Gyeong Joon Moon, Sung Ig Cho, Yong Beom Lee, Byoung Joo Gwag. Effects of collagen-induced rheumatoid arthritis on amyloidosis and microvascular pathology in APP/PS1 mice.
BMC neuroscience.
2011 Oct; 12(?):106. doi:
10.1186/1471-2202-12-106. [PMID: 22029666] - Andrew B Nowakowski, David H Petering. Reactions of the fluorescent sensor, Zinquin, with the zinc-proteome: adduct formation and ligand substitution.
Inorganic chemistry.
2011 Oct; 50(20):10124-33. doi:
10.1021/ic201076w. [PMID: 21905645] - Kun Li, Yunpeng Diao, Houli Zhang, Shouyu Wang, Zhen Zhang, Bo Yu, Shanshan Huang, Hong Yang. Tannin extracts from immature fruits of Terminalia chebula Fructus Retz. promote cutaneous wound healing in rats.
BMC complementary and alternative medicine.
2011 Oct; 11(?):86. doi:
10.1186/1472-6882-11-86. [PMID: 21982053] - Chika Tateda, Kanako Watanabe, Tomonobu Kusano, Yoshihiro Takahashi. Molecular and genetic characterization of the gene family encoding the voltage-dependent anion channel in Arabidopsis.
Journal of experimental botany.
2011 Oct; 62(14):4773-85. doi:
10.1093/jxb/err113. [PMID: 21705391] - Xiao-San Huang, Tao Luo, Xing-Zheng Fu, Qi-Jun Fan, Ji-Hong Liu. Cloning and molecular characterization of a mitogen-activated protein kinase gene from Poncirus trifoliata whose ectopic expression confers dehydration/drought tolerance in transgenic tobacco.
Journal of experimental botany.
2011 Oct; 62(14):5191-206. doi:
10.1093/jxb/err229. [PMID: 21778184] - Alex T Chow, Anthony T O'Geen, Randy A Dahlgren, Francisco J Díaz, Kin-Hang Wong, Po-Keung Wong. Reactivity of litter leachates from California oak woodlands in the formation of disinfection by-products.
Journal of environmental quality.
2011 Sep; 40(5):1607-16. doi:
10.2134/jeq2010.0488. [PMID: 21869524] - Hiromitsu Kawata, Shinichi Arai, Toshito Nakagawa, Nobuyuki Ishikura, Ayako Nishimoto, Hitoshi Yoshino, Takuya Shiraishi, Kazutaka Tachibana, Ryo Nakamura, Haruhiko Sato. Biological properties of androgen receptor pure antagonist for treatment of castration-resistant prostate cancer: optimization from lead compound to CH5137291.
The Prostate.
2011 Sep; 71(12):1344-56. doi:
10.1002/pros.21351. [PMID: 21308717] - Tadeusz M Zielonka, Urszula Demkow, Dorota Michalowska-Mitczuk, Malgorzata Filewska, Beata Bialas, Katarzyna Zycinska, Michael H Obrowski, Jan Kus, Ewa Skopinska-Rozewska. Angiogenic activity of sera from pulmonary tuberculosis patients in relation to IL-12p40 and TNFα serum levels.
Lung.
2011 Aug; 189(4):351-7. doi:
10.1007/s00408-011-9291-6. [PMID: 21603999] - Neta Shlezinger, Anna Minz, Yonatan Gur, Ido Hatam, Yasin F Dagdas, Nicholas J Talbot, Amir Sharon. Anti-apoptotic machinery protects the necrotrophic fungus Botrytis cinerea from host-induced apoptotic-like cell death during plant infection.
PLoS pathogens.
2011 Aug; 7(8):e1002185. doi:
10.1371/journal.ppat.1002185. [PMID: 21876671] - Pannaga Krishnamurthy, Kosala Ranathunge, Shraddha Nayak, Lukas Schreiber, M K Mathew. Root apoplastic barriers block Na+ transport to shoots in rice (Oryza sativa L.).
Journal of experimental botany.
2011 Aug; 62(12):4215-28. doi:
10.1093/jxb/err135. [PMID: 21558150] - Floriane L'Haridon, Angélique Besson-Bard, Matteo Binda, Mario Serrano, Eliane Abou-Mansour, Francine Balet, Henk-Jan Schoonbeek, Stephane Hess, Ricardo Mir, José Léon, Olivier Lamotte, Jean-Pierre Métraux. A permeable cuticle is associated with the release of reactive oxygen species and induction of innate immunity.
PLoS pathogens.
2011 Jul; 7(7):e1002148. doi:
10.1371/journal.ppat.1002148. [PMID: 21829351] - Xi Chen, Shihui Xing, Yanqing Feng, Songlin Chen, Zhong Pei, Chuhuai Wang, Xiuling Liang. Early stage transplantation of bone marrow cells markedly ameliorates copper metabolism and restores liver function in a mouse model of Wilson disease.
BMC gastroenterology.
2011 Jun; 11(?):75. doi:
10.1186/1471-230x-11-75. [PMID: 21676234] - Antoine Peraldi, Giovanni Beccari, Andrew Steed, Paul Nicholson. Brachypodium distachyon: a new pathosystem to study Fusarium head blight and other Fusarium diseases of wheat.
BMC plant biology.
2011 Jun; 11(?):100. doi:
10.1186/1471-2229-11-100. [PMID: 21639892] - Olatz Pampliega, María Domercq, Federico N Soria, Pablo Villoslada, Alfredo Rodríguez-Antigüedad, Carlos Matute. Increased expression of cystine/glutamate antiporter in multiple sclerosis.
Journal of neuroinflammation.
2011 Jun; 8(?):63. doi:
10.1186/1742-2094-8-63. [PMID: 21639880] - Philip Wolff, Isabelle Weinhofer, Jonathan Seguin, Pawel Roszak, Christian Beisel, Mark T A Donoghue, Charles Spillane, Magnus Nordborg, Marc Rehmsmeier, Claudia Köhler. High-resolution analysis of parent-of-origin allelic expression in the Arabidopsis Endosperm.
PLoS genetics.
2011 Jun; 7(6):e1002126. doi:
10.1371/journal.pgen.1002126. [PMID: 21698132] - Alan Wayne Jones. Early drug discovery and the rise of pharmaceutical chemistry.
Drug testing and analysis.
2011 Jun; 3(6):337-44. doi:
10.1002/dta.301. [PMID: 21698778] - Norio Nonomura, Hitoshi Takayama, Masashi Nakayama, Yasutomo Nakai, Atsunari Kawashima, Masatoshi Mukai, Akira Nagahara, Katsuyuki Aozasa, Akira Tsujimura. Infiltration of tumour-associated macrophages in prostate biopsy specimens is predictive of disease progression after hormonal therapy for prostate cancer.
BJU international.
2011 Jun; 107(12):1918-22. doi:
10.1111/j.1464-410x.2010.09804.x. [PMID: 21044246] - Juan Zhang, Rachel D Grindstaff, Sheau-Fung Thai, Sandra A Murray, Michael Kohan, Carl F Blackman. Chloral hydrate decreases gap junction communication in rat liver epithelial cells.
Cell biology and toxicology.
2011 Jun; 27(3):207-16. doi:
10.1007/s10565-011-9182-x. [PMID: 21243523] - Kai Yang, Dong Qiang, Sarah Delaney, Rhea Mehta, W R Bruce, Peter J O'Brien. Differences in glyoxal and methylglyoxal metabolism determine cellular susceptibility to protein carbonylation and cytotoxicity.
Chemico-biological interactions.
2011 May; 191(1-3):322-9. doi:
10.1016/j.cbi.2011.02.012. [PMID: 21334317] - Pablo Carbonell-Bejerano, Cristina Urbez, Antonio Granell, Juan Carbonell, Miguel A Perez-Amador. Ethylene is involved in pistil fate by modulating the onset of ovule senescence and the GA-mediated fruit set in Arabidopsis.
BMC plant biology.
2011 May; 11(?):84. doi:
10.1186/1471-2229-11-84. [PMID: 21575215] - Yen-Ta Chen, Cheuk-Kwan Sun, Yu-Chun Lin, Li-Teh Chang, Yung-Lung Chen, Tzu-Hsien Tsai, Sheng-Ying Chung, Sarah Chua, Ying-Hsien Kao, Chia-Hong Yen, Pei-Lin Shao, Kuan-Cheng Chang, Steve Leu, Hon-Kan Yip. Adipose-derived mesenchymal stem cell protects kidneys against ischemia-reperfusion injury through suppressing oxidative stress and inflammatory reaction.
Journal of translational medicine.
2011 May; 9(?):51. doi:
10.1186/1479-5876-9-51. [PMID: 21545725] - Moritaka Nakamura, Masatsugu Toyota, Masao Tasaka, Miyo Terao Morita. An Arabidopsis E3 ligase, SHOOT GRAVITROPISM9, modulates the interaction between statoliths and F-actin in gravity sensing.
The Plant cell.
2011 May; 23(5):1830-48. doi:
10.1105/tpc.110.079442. [PMID: 21602290] - Arne Solberg, Olav A Haugen, Trond Viset, Anders Bergh, Ilker Tasdemir, Göran Ahlgren, Anders Widmark, Anders Angelsen. Residual prostate cancer in patients treated with endocrine therapy with or without radical radiotherapy: a side study of the SPCG-7 randomized trial.
International journal of radiation oncology, biology, physics.
2011 May; 80(1):55-61. doi:
10.1016/j.ijrobp.2010.01.072. [PMID: 20598453] - Daoquan Xiang, Prakash Venglat, Chabane Tibiche, Hui Yang, Eddy Risseeuw, Yongguo Cao, Vivijan Babic, Mathieu Cloutier, Wilf Keller, Edwin Wang, Gopalan Selvaraj, Raju Datla. Genome-wide analysis reveals gene expression and metabolic network dynamics during embryo development in Arabidopsis.
Plant physiology.
2011 May; 156(1):346-56. doi:
10.1104/pp.110.171702. [PMID: 21402797] - Crystal Sloan, Joseph Tuinei, Katherine Nemetz, Jonathan Frandsen, Jamie Soto, Noah Wride, Tomoki Sempokuya, Luis Alegria, Heiko Bugger, E Dale Abel. Central leptin signaling is required to normalize myocardial fatty acid oxidation rates in caloric-restricted ob/ob mice.
Diabetes.
2011 May; 60(5):1424-34. doi:
10.2337/db10-1106. [PMID: 21441440] - Xianhuo Wang, Xingmei Duan, Guangli Yang, Xiaoyan Zhang, Linyu Deng, Hao Zheng, Chongyang Deng, Jiaolin Wen, Ning Wang, Cheng Peng, Xia Zhao, Yuquan Wei, Lijuan Chen. Honokiol crosses BBB and BCSFB, and inhibits brain tumor growth in rat 9L intracerebral gliosarcoma model and human U251 xenograft glioma model.
PloS one.
2011 Apr; 6(4):e18490. doi:
10.1371/journal.pone.0018490. [PMID: 21559510] - Prakash Venglat, Daoquan Xiang, Shuqing Qiu, Sandra L Stone, Chabane Tibiche, Dustin Cram, Michelle Alting-Mees, Jacek Nowak, Sylvie Cloutier, Michael Deyholos, Faouzi Bekkaoui, Andrew Sharpe, Edwin Wang, Gordon Rowland, Gopalan Selvaraj, Raju Datla. Gene expression analysis of flax seed development.
BMC plant biology.
2011 Apr; 11(?):74. doi:
10.1186/1471-2229-11-74. [PMID: 21529361] - Yvan Kraepiel, Jacques Pédron, Oriane Patrit, Elizabeth Simond-Côte, Victor Hermand, Frédérique Van Gijsegem. Analysis of the plant bos1 mutant highlights necrosis as an efficient defence mechanism during D. dadantii/Arabidospis thaliana interaction.
PloS one.
2011 Apr; 6(4):e18991. doi:
10.1371/journal.pone.0018991. [PMID: 21533045] - Maria Dolores Gomez, Cristina Urbez, Miguel A Perez-Amador, Juan Carbonell. Characterization of constricted fruit (ctf) mutant uncovers a role for AtMYB117/LOF1 in ovule and fruit development in Arabidopsis thaliana.
PloS one.
2011 Apr; 6(4):e18760. doi:
10.1371/journal.pone.0018760. [PMID: 21533201] - Matthew R Willmann, Andrew J Mehalick, Rachel L Packer, Pablo D Jenik. MicroRNAs regulate the timing of embryo maturation in Arabidopsis.
Plant physiology.
2011 Apr; 155(4):1871-84. doi:
10.1104/pp.110.171355. [PMID: 21330492] - Lata Jayaram, Sanjeev Chunilal, Sandy Pickering, Richard E Ruffin, Peter D Zalewski. Sputum zinc concentration and clinical outcome in older asthmatics.
Respirology (Carlton, Vic.).
2011 Apr; 16(3):459-66. doi:
10.1111/j.1440-1843.2011.01932.x. [PMID: 21261783] - Hironori Fujita, Koichi Toyokura, Kiyotaka Okada, Masayoshi Kawaguchi. Reaction-diffusion pattern in shoot apical meristem of plants.
PloS one.
2011 Mar; 6(3):e18243. doi:
10.1371/journal.pone.0018243. [PMID: 21479227] - Yun Wang, Lei Jing, Xiao-Min Zhao, Ji-Ju Han, Zuo-Li Xia, Shu-Cun Qin, Ya-Ping Wu, Xue-Jun Sun. Protective effects of hydrogen-rich saline on monocrotaline-induced pulmonary hypertension in a rat model.
Respiratory research.
2011 Mar; 12(?):26. doi:
10.1186/1465-9921-12-26. [PMID: 21375753] - Fei Xiao, Zhiying Huang, Houkai Li, Junjie Yu, Chunxia Wang, Shanghai Chen, Qingshu Meng, Ying Cheng, Xiang Gao, Jia Li, Yong Liu, Feifan Guo. Leucine deprivation increases hepatic insulin sensitivity via GCN2/mTOR/S6K1 and AMPK pathways.
Diabetes.
2011 Mar; 60(3):746-56. doi:
10.2337/db10-1246. [PMID: 21282364] - David Schwarz, Damaris Bloom, Rocío Castro, Oné R Pagán, C A Jiménez-Rivera. Parthenolide Blocks Cocaine's Effect on Spontaneous Firing Activity of Dopaminergic Neurons in the Ventral Tegmental Area.
Current neuropharmacology.
2011 Mar; 9(1):17-20. doi:
10.2174/157015911795017010. [PMID: 21886554] - Steffen Fischer, Christian Wiese, Eva Grosse Maestrup, Achim Hiller, Winnie Deuther-Conrad, Matthias Scheunemann, Dirk Schepmann, Jörg Steinbach, Bernhard Wünsch, Peter Brust. Molecular imaging of σ receptors: synthesis and evaluation of the potent σ1 selective radioligand [18F]fluspidine.
European journal of nuclear medicine and molecular imaging.
2011 Mar; 38(3):540-51. doi:
10.1007/s00259-010-1658-z. [PMID: 21072511] - Yongil Yang, Dale T Karlson. Overexpression of AtCSP4 affects late stages of embryo development in Arabidopsis.
Journal of experimental botany.
2011 Mar; 62(6):2079-91. doi:
10.1093/jxb/erq400. [PMID: 21282328] - Hanna Paatela, Veera Vihma, Matti Jauhiainen, Eero Mervaala, Matti J Tikkanen. Dehydroepiandrosterone fatty acyl esters in high density lipoprotein: interaction with human vascular endothelial cells and vascular responses ex vivo.
Steroids.
2011 Mar; 76(4):376-80. doi:
10.1016/j.steroids.2010.12.007. [PMID: 21168430] - Peter W Stacpoole. The dichloroacetate dilemma: environmental hazard versus therapeutic goldmine--both or neither?.
Environmental health perspectives.
2011 Feb; 119(2):155-8. doi:
10.1289/ehp.1002554. [PMID: 20920954]