2150-11-0 (BioDeep_00000861877)

PANOMIX_OTCML-2023

代谢物信息卡片

4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-hydroxy-

化学式: C15H10O5 (270.052821)
中文名称: 3,4,7-三羟基黄酮
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=C(C=C1C2=CC(=O)C3=C(O2)C=C(C=C3)O)O)O
InChI: InChI=1S/C15H10O5/c16-9-2-3-10-12(18)7-14(20-15(10)6-9)8-1-4-11(17)13(19)5-8/h1-7,16-17,19H

描述信息

同义名列表

13 个代谢物同义名

4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-hydroxy-; 2-(3,4-Dihydroxyphenyl)-7-hydroxy-4H-1-benzopyran-4-one; 2-(3,4-dihydroxyphenyl)-7-hydroxy-chromen-4-one; 2-(3,4-dihydroxyphenyl)-7-hydroxychromen-4-one; 2-(3,4-dihydroxyphenyl)-7-hydroxy-4-chromenone; 5-18-04-00590 (Beilstein Handbook Reference); 2-(3,4-dihydroxyphenyl)-7-hydroxy-chromone; 3,4,7-Trihydroxyflavone; 7,3,4-Trihydroxyflavone; ZINC00057766; BRN 0253031; 2150-11-0; ST056259

数据库引用编号

5 个数据库交叉引用编号

ChEBI: CHEBI:196247
PubChem: 5322065
ChEMBL: CHEMBL301624
CAS: 104666-14-0
CAS: 2150-11-0

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

42 个相关的物种来源信息

3809 - Acacia confusa: 10.1021/JF901498Q
138022 - Acacia fasciculifera: 10.1039/P19810002483
149633 - Baptisia australis:
313912 - Baptisia bracteata:
1969220 - Baptisia calycosa:
313913 - Baptisia cinerea:
1969221 - Baptisia lanceolata:
1969222 - Baptisia lecontei:
1969223 - Baptisia megacarpa:
1871516 - Baptisia perfoliata:
1969224 - Baptisia simplicifolia:
210348 - Brucea javanica: 10.1002/JCCS.200800033
56060 - Butea monosperma: 10.1248/CPB.57.428
228520 - Cheniella glauca: 10.1016/J.BMCL.2015.05.089
165299 - Cissus discolor: 10.1248/CPB.57.1089
384038 - Cyclopia intermedia: 10.1021/JF0210730
155109 - Cyclopia subternata: 10.1021/JF040097Z
1079072 - Dipteryx lacunifera: 10.1002/HLCA.200890233
66811 - Medicago coronata: 10.1016/0305-1978(82)90048-5
70952 - Medicago laciniata: 10.1016/0305-1978(82)90048-5
75626 - Medicago littoralis: 10.1016/0305-1978(82)90048-5
70959 - Medicago monspeliaca: 10.1016/0305-1978(82)90048-5
70962 - Medicago orbicularis: 10.1016/0305-1978(82)90048-5
47084 - Medicago polymorpha: 10.1016/0305-1978(82)90048-5
3879 - Medicago sativa: 10.1016/0305-1978(82)90048-5
200492 - Sophora alopecuroides: 10.1007/S10600-009-9360-8
49839 - Sophora davidii: 10.1016/0031-9422(73)85021-6
70607 - Sophora microphylla: 10.1016/0031-9422(73)85021-6
76398 - Sophora prostrata: 10.1016/0031-9422(73)85021-6
1196212 - Sophora viciifolia: 10.1016/0031-9422(73)85021-6
455371 - Spatholobus suberectus: 10.1016/J.PHYTOCHEM.2006.05.008
114322 - Thermopsis macrophylla: 10.1016/S0031-9422(00)88458-7
2805045 - Thermopsis mollis: 10.1016/S0031-9422(00)88458-7
61122 - Thermopsis rhombifolia: 10.1016/S0031-9422(00)88458-7
114325 - Thermopsis villosa: 10.1016/S0031-9422(00)88458-7
390135 - Trigonella anguina: 10.1016/0305-1978(82)90048-5
200964 - Trigonella coerulescens: 10.1016/0305-1978(82)90048-5
78534 - Trigonella foenum-graecum: 10.1016/0305-1978(82)90048-5
1210111 - Trigonella maritima: 10.1016/0305-1978(82)90048-5
119386 - Trigonella spicata: 10.1016/0305-1978(82)90048-5
3906 - Vicia faba: 10.1021/JF00002A006
33090 - 降香: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Jinfeng Yang, Yong Soo Kwon, Myong Jo Kim. Antimicrobial activity and active compounds of a Rhus verniciflua Stokes extract. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2018 Nov; 73(11-12):457-463. doi: 10.1515/znc-2018-0054. [PMID: 30183668]
Joachim K Dzotam, Ingrid Konga Simo, Gabin Bitchagno, Ilhami Celik, Louis P Sandjo, Pierre Tane, Victor Kuete. In vitro antibacterial and antibiotic modifying activity of crude extract, fractions and 3',4',7-trihydroxyflavone from Myristica fragrans Houtt against MDR Gram-negative enteric bacteria. BMC complementary and alternative medicine. 2018 Jan; 18(1):15. doi: 10.1186/s12906-018-2084-1. [PMID: 29334931]
Ignas Grigalius, Vilma Petrikaite. Relationship between Antioxidant and Anticancer Activity of Trihydroxyflavones. Molecules (Basel, Switzerland). 2017 Dec; 22(12):. doi: 10.3390/molecules22122169. [PMID: 29215574]
Yingzhan Tang, Junhong Ling, Peng Zhang, Xiangrong Zhang, Na Zhang, Wenli Wang, Jiayuan Li, Ning Li. Potential therapeutic agents for circulatory diseases from Bauhinia glauca Benth.subsp. pernervosa. (Da Ye Guan Men). Bioorganic & medicinal chemistry letters. 2015 Aug; 25(16):3217-20. doi: 10.1016/j.bmcl.2015.05.089. [PMID: 26096681]
Daniela Ribeiro, Marisa Freitas, Sara M Tomé, Artur M S Silva, Graça Porto, Eurico J Cabrita, M Manuel B Marques, Eduarda Fernandes. Inhibition of LOX by flavonoids: a structure-activity relationship study. European journal of medicinal chemistry. 2014 Jan; 72(?):137-45. doi: 10.1016/j.ejmech.2013.11.030. [PMID: 24368208]
Dana Atrahimovich, Jacob Vaya, Soliman Khatib. The effects and mechanism of flavonoid-rePON1 interactions. Structure-activity relationship study. Bioorganic & medicinal chemistry. 2013 Jun; 21(11):3348-55. doi: 10.1016/j.bmc.2013.02.055. [PMID: 23623675]
Muna Ali Abdalla, Hartmut Laatsch. Flavonoids from Sudanese Albizia zygia (Leguminosae, subfamily Mimosoideae), a plant with antimalarial potency. African journal of traditional, complementary, and alternative medicines : AJTCAM. 2012; 9(1):56-8. doi: 10.4314/ajtcam.v9i1.8. [PMID: 23983320]
Yu-Tang Tung, Shang-Tzen Chang. Inhibition of xanthine oxidase by Acacia confusa extracts and their phytochemicals. Journal of agricultural and food chemistry. 2010 Jan; 58(2):781-6. doi: 10.1021/jf901498q. [PMID: 20047272]
Gui-Ping Zhang, Zhi-Yong Xiao, Jamal Rafique, Mohammad Arfan, Peter J Smith, Carmen A Lategan, Li-Hong Hu. Antiplasmodial isoflavanones from the roots of Sophora mollis. Journal of natural products. 2009 Jul; 72(7):1265-8. doi: 10.1021/np900144c. [PMID: 19572738]
Jyh-Horng Wu, Yu-Tang Tung, Shih-Chang Chien, Sheng-Yang Wang, Yueh-Hsiung Kuo, Lie-Fen Shyur, Shang-Tzen Chang. Effect of phytocompounds from the heartwood of Acacia confusa on inflammatory mediator production. Journal of agricultural and food chemistry. 2008 Mar; 56(5):1567-73. doi: 10.1021/jf072922s. [PMID: 18254591]
Mei-Hsien Lee, Yi-Pei Lin, Feng-Lin Hsu, Gui-Rong Zhan, Kun-Ying Yen. Bioactive constituents of Spatholobus suberectus in regulating tyrosinase-related proteins and mRNA in HEMn cells. Phytochemistry. 2006 Jun; 67(12):1262-70. doi: 10.1016/j.phytochem.2006.05.008. [PMID: 16782143]
Mee Jung Jung, Hae Young Chung, Sam Sik Kang, Jin Ho Choi, Kae Sun Bae, Jae Sue Choi. Antioxidant activity from the stem bark of Albizzia julibrissin. Archives of pharmacal research. 2003 Jun; 26(6):458-62. doi: 10.1007/bf02976862. [PMID: 12877554]
F A van Acker, J A Hageman, G R Haenen, W J van Der Vijgh, A Bast, W M Menge. Synthesis of novel 3,7-substituted-2-(3',4'-dihydroxyphenyl)flavones with improved antioxidant activity. Journal of medicinal chemistry. 2000 Oct; 43(20):3752-60. doi: 10.1021/jm000951n. [PMID: 11020290]
L Costantino, G Rastelli, M C Gamberini, J A Vinson, P Bose, A Iannone, M Staffieri, L Antolini, A Del Corso, U Mura, A Albasini. 1-Benzopyran-4-one antioxidants as aldose reductase inhibitors. Journal of medicinal chemistry. 1999 Jun; 42(11):1881-93. doi: 10.1021/jm980441h. [PMID: 10354396]