Acivicin (BioDeep_00000659521)
Secondary id: BioDeep_00000900985
代谢物信息卡片
Acivicin
化学式: C5H7ClN2O3 (178.0145182)
中文名称: 阿西维辛
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1C(ON=C1Cl)C(C(=O)O)N
InChI: InChI=1S/C5H7ClN2O3/c6-3-1-2(11-8-3)4(7)5(9)10/h2,4H,1,7H2,(H,9,10)/t2-,4-/m0/s1
描述信息
An L-alpha-amino acid that is L-alanine in which the methyl group is replaced by a (5S)-3-chloro-4,5-dihydro-1,2-oxazol-5-yl group. A glutamine analogue antimetabolite, it interferes with glutamate metabolism and several glutamate-dependent synthetic enzymes. It is obtained as a fermentation product of Streptomyces sviceus bacteria.
C471 - Enzyme Inhibitor > C2158 - Glutamine Amidotransferase Inhibitor
D000890 - Anti-Infective Agents > D000935 - Antifungal Agents
D009676 - Noxae > D000963 - Antimetabolites
D000970 - Antineoplastic Agents
D004791 - Enzyme Inhibitors
同义名列表
1 个代谢物同义名
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:74545
- KEGGdrug: D02755
- PubChem: 294641
- ChEMBL: CHEMBL1231101
- CAS: 42228-92-2
- MetaboLights: MTBLC74545
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- K Maeda, Y Nakajima, T Motoyama, Y Kitou, T Kosaki, T Saito, T Nishiuchi, K Kanamaru, H Osada, T Kobayashi, M Kimura. Effects of acivicin on growth, mycotoxin production and virulence of phytopathogenic fungi.
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The Biochemical journal.
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Cellular microbiology.
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World journal of gastroenterology.
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Hepatology (Baltimore, Md.).
2002 Jan; 35(1):74-81. doi:
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Cancer research.
1994 Nov; 54(22):5925-9. doi:
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Renal physiology and biochemistry.
1994 Nov; 17(6):307-15. doi:
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Xenobiotica; the fate of foreign compounds in biological systems.
1994 Sep; 24(9):909-19. doi:
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The Journal of clinical investigation.
1994 Sep; 94(3):1218-25. doi:
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The Journal of biological chemistry.
1994 Aug; 269(34):21435-9. doi:
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European journal of biochemistry.
1994 Jul; 223(2):617-24. doi:
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Journal of applied toxicology : JAT.
1994 May; 14(3):201-6. doi:
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Transfusion.
1994 May; 34(5):421-6. doi:
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Toxicology letters.
1994 Apr; 71(2):161-8. doi:
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Journal of applied physiology (Bethesda, Md. : 1985).
1994 Mar; 76(3):1279-84. doi:
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Toxicology.
1994 Feb; 86(3):175-86. doi:
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Cell biochemistry and function.
1994 Jan; 12(1):11-9. doi:
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Canadian journal of physiology and pharmacology.
1994 Jan; 72(1):50-6. doi:
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Advances in enzyme regulation.
1994; 34(?):71-89. doi:
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Archives of toxicology.
1994; 68(1):15-23. doi:
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The American journal of physiology.
1993 Dec; 265(6 Pt 1):G1128-34. doi:
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Chemico-biological interactions.
1993 Oct; 89(1):35-47. doi:
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Renal physiology and biochemistry.
1993 Jul; 16(4):203-11. doi:
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Biochemical medicine and metabolic biology.
1993 Jun; 49(3):338-50. doi:
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Toxicology and applied pharmacology.
1993 May; 120(1):1-7. doi:
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The Biochemical journal.
1993 Mar; 290 ( Pt 3)(?):759-64. doi:
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The Journal of pharmacology and experimental therapeutics.
1993 Feb; 264(2):776-82. doi:
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Archives of toxicology.
1993; 67(9):613-21. doi:
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Archives of toxicology.
1993; 67(10):696-705. doi:
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Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine.
1993; 6(3):171-8. doi:
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Toxicology and applied pharmacology.
1992 Dec; 117(2):200-7. doi:
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The American journal of physiology.
1992 May; 262(5 Pt 2):F777-83. doi:
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European journal of pharmacology.
1992 May; 228(1):9-14. doi:
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Toxicology.
1992; 72(1):17-26. doi:
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The Journal of clinical investigation.
1992 Jan; 89(1):109-16. doi:
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